Patellofemoral Joint Loading During the Performance of the Forward and Side Lunge with Step Height Variations by Rafael Escamilla, Naiquan Zheng, Toran D MacLeod, Rodney Imamura, Kevin E. Wilk, Shangcheng Wang, Irv Rubenstein, Kyle Yamashiro, Glenn S. Fleisig

“…Electromyographic, ground reaction force, and kinematic variables were collected and input into a biomechanical optimization model, and patellofemoral joint force and stress were calculated as a function of knee angle during the lunge descent and ascent and assessed with a repeated measures 2-way ANOVA (p<0.05)…”
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How prepared is Nigeria digital payment for health workers? A landscape analysis by Folashayo Peter Adeniji, David Ayobami Adewole, Segun Bello, Elizabeth Ekirapa, Juliet Aweko, Vincent Michael Kiberu, Charles Opio, Peter Waiswa, Olufunmilayo Ibitola Fawole

“…Abstract Introduction Stakeholders in the health sector have advocated for the optimization of digital payment channels in low-and-middle-income countries in order to improve program outcomes. …”
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The role of homogenization cycles and Poloxamer 188 on the quality of mitochondria isolated for use in mitochondrial transplantation therapy by Ryosuke Takegawa, Kei Hayashida, Atsushi Murao, Yusuke Endo, Cyrus E. Kuschner, Jacob Kazmi, Eriko Nakamura, Ping Wang, Lance B. Becker

“…These strategies offer promising strategies for optimizing MTx protocols. Further refinement of these techniques is necessary for their clinical application in MTx therapy.…”
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Establishment of the first marine mollusk cell line from scallop (Chlamys farreri) trochophore by Zhenkui Qin, Aichang Ji, Meng Yan, Danwen Liu, Xixi Li, Xiaoli Hu, Zhifeng Zhang

“…In the present study, FBS, scallop serum, scallop ovarian extracts, and FeCl3 were added to the L-15 basic medium to develop an optimized culture medium (L15-CFIIIFe) for culturing trochophore larval cells of Chlamys farreri, an important mariculture scallop in China. …”
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A DFT Analysis on Antioxidant and Antiradical Activities from Anthraquinones Isolated from the Cameroonian Flora by Judith Caroline Ngo Nyobe, Laurent Gael Eyia Andiga, Désiré Bikele Mama, Baruch Ateba Amana, Joseph Zobo Mfomo, Toze Flavien Aristide Alfred, Jean Claude Ndom

“…The topological analysis of optimized structures indicates that the strength of the hydrogen bonds formed is situated between 44.205 and 52.001 kJ/mol. …”
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Tacrolimus- and Mycophenolate-Mediated Toxicity: Clinical Considerations and Options in Management of Post-Transplant Patients by Alan D. Kaye, Shivam S. Shah, Coplen D. Johnson, Adalyn S. De Witt, Austin S. Thomassen, Charles P. Daniel, Shahab Ahmadzadeh, Sridhar Tirumala, Kristin Nicole Bembenick, Adam M. Kaye, Sahar Shekoohi

“…This narrative review underscores the importance of personalized medicine and advanced monitoring in optimizing post-transplant care.…”
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Evolutionary Algorithms and Quantum Computing: Recent Advances, Opportunities, and Challenges by Junaid Ur Rehman, Muhammad Shohibul Ulum, Abdurrahman Wachid Shaffar, Amirul Adlil Hakim, Mujirin, Zaid Abdullah, Hayder Al-Hraishawi, Symeon Chatzinotas, Hyundong Shin

“…Additionally, the practical constraints associated with current quantum computers have highlighted a critical need for classical heuristic methods to optimize the tunable parameters of quantum circuits. …”
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Sustained effects of bladder point-of-care ultrasound simulation exercise on nursing students: A prospective cohort study by Tomoyoshi Naito, Akiko Hashizumi, Masako Sakai, Emiko Yamamura, Miho Iwase, Kiyomi Yamada, Masako Watanabe, Nobuo Kimura, Takako Kato, Eiko Fujimoto, Rie Kashihara

“…The OSAUS scores for several subdomains, including image optimization, systematic reviews, image interpretation, test documentation, and medical decision-making, increased significantly. …”
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Formation Characteristics of PCDD/Fs in the Co-combustion and Pyrolysis Process of Coal and Sewage Sludge by Mumin Rao, Xiangbo Zou, Ji Ye, Yunfeng Ma, Tieying Mao, Xiaoqing Lin, Xiaodong Li, Jianhua Yan, Shiwei Qin, Cao Kuang

“…The results paved the way for further optimization on the operation of co-combustion of coal and SS and assist in controlling the PCDD/F emission from co-combustion process.…”
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Artificial Liver Support Systems in Acute Liver Failure and Acute-on-Chronic Liver Failure: Systematic Review and Meta-Analysis by Robert S. Brown, Jr, MD, MPH, Robert A. Fisher, MD, FACS, TACC, Ram M. Subramanian, MD, MBA, Adam Griesemer, MD, Milene Fernandes, PharmD, MSc, William H. Thatcher, MS, Kathryn Stiede, BS, Michael Curtis, PhD

“…Despite no significant pooled effects of NBAL/BAL devices, the available evidence calls for further research and development of extracorporeal liver support systems, with larger RCTs and optimization of patient selection, perfusion durability, and treatment protocols.…”
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Efficacy and Safety Assessment of Antifungal Prophylaxis with Posaconazole Using Therapeutic Drug Monitoring in Pediatric Patients with Oncohematological Disorders—A Single-Centre... by Karolina Liszka, Paweł Marschollek, Dawid Przystupski, Jowita Frączkiewicz, Monika Mielcarek-Siedziuk, Igor Olejnik, Zuzanna Gamrot, Natalia Haze, Agnieszka Kwella, Paulina Zalewska, Matylda Resztak, Marek Ussowicz, Krzysztof Kałwak

“…Conclusions: TDM allows the identification of patients receiving non-optimal treatment and offers an opportunity to improve the efficacy and safety of the therapy. …”
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Analysis of Radio Science Data from the KaT Instrument of the 3GM Experiment During JUICE’s Early Cruise Phase by Paolo Cappuccio, Andrea Sesta, Mauro Di Benedetto, Daniele Durante, Umberto De Filippis, Ivan di Stefano, Luciano Iess, Ruaraidh Mackenzie, Bernard Godard

“…The radiometric data were fitted using both NASA’s Mission Analysis, Operations, and Navigation Toolkit Environment (MONTE) and ESA’s General Orbit Determination and Optimization Toolkit (GODOT) software. The comparison of the orbital solutions showed an excellent agreement. …”
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Concurrent Panniculectomy With Abdominal Wall Reconstruction: A Propensity-scored Matched Study of Quality Improvement Outcomes by Alexis M. Holland, MD, William R. Lorenz, MD, Matthew N. Marturano, MD, Rose K. Hollingsworth, BA, Gregory T. Scarola, MS, Brittany S. Mead, MD, B. Todd Heniford, MD, Vedra A. Augenstein, MD

“…Despite patient complexity, outcomes of CP-AWR improved with implementation of evidence-based-practice changes in preoperative optimization, intraoperative technique, and postoperative care. …”
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Design of Conformal Cooling of an Additively Printed Aluminium Die-Casting Mold Component by J. Sviželová, L. Socha, A. Mohamed, M. Pinta, K. Koza, T. Sellner, K. Gryc, M. Dvořák, M. Roh

“…Shape modifications were made by topology optimization to reduce the volume of the insert and achieve material savings. 3D printing was chosen as the production technology due to the wider possibilities regarding the variability of the shape of the internal cooling channels. …”
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Cellular heterogeneity and cytokine signatures in acute myeloid leukemia: A novel prognostic model by Jinxia Cao, Bin Hu, Tianqi Li, Dan Fang, ling Jiang, Jun Wang

“…Our findings represent a pivotal step toward the realization of personalized medicine in the management of AML, offering new avenues for research and treatment optimization in this challenging disease landscape.…”
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Simulation and experimental study on olive drop injury by Weike Lan, Haotian Mu, Di Xin, Shijia Pan, Yuncai Yan, Wen Gao, Zijie Niu, Dongyan Zhang, Jun Zhang, Yongjie Cui

“…In this study, vibration harvesting drop tests and finite element simulations were performed on the olive variety ''Leccio'' to optimize the collision parameters to evaluate and predict the damage level and damage resistance of olives. …”
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Effects of Ni content on the microstructure and properties of laser powder bed fusion-processed Fe–18Cr–XNi alloys by Yongchao Lu, Xiaoqun Li, Yazhou He, Yaqing Hou, Fafa Li, Yao Lu, Hao Zhang, Lanting Zhang, Hong Wang, Hang Su

“…This work provides a fundamental reference for composition tuning and performance optimization of widely used 300-series alloys in LPBF research.…”
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Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis by Kou Y, Tian Y, Ha Y, Wang S, Sun X, Lv S, Luo B, Yang Y, Qin L

“…Pairwise correlation analysis further revealed interactions among these variables.Conclusion: The RF model exhibited robust predictive power for sepsis in leukemia patients, providing clinicians with a valuable tool for early risk assessment and the optimization of treatment strategies.Keywords: leukemia, sepsis, prediction model, biomarkers, machine learning…”
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Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence by Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

“…Results In this work, we discovered that lipid nanoparticle (LNP) can infiltrate and deliver FGF18 mRNA deeper in the cartilage than proteins. After mRNA UTR optimization and chemical modification, the expression of FGF18 can last up to 6 days in the cartilage. …”
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Proof of concept of fully automated adaptive workflow for head and neck radiotherapy treatments with a conventional linear accelerator by Gaia Muti, Marco M. J. Felisi, Angelo F. Monti, Chiara Carsana, Roberto Pellegrini, Edoardo Salmeri, Mauro Palazzi, Paola E. Colombo

“…IntroductionThe objective of this study is to evaluate the performance of an automatic workflow for head-and-neck (H&amp;N) radiotherapy using a multi-atlas based auto-contouring software and an a-priori multicriteria plan optimization algorithm and implement an adaptive online approach with CBCT images. …”
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