Pear Juice Clarification Using Polygalacturonase from Beauveria bassiana : Effects on Rheological, Antioxidant and Quality Properties by Ayodeji Emmanuel Amobonye, Prashant Bhagwat, Faith Matiza Ruzengwe, Suren Singh, Santhosh Pillai

“…In this study, pear juice was effectively clarified using partially purified polygalacturonase from an entomopathogenic fungal endophyte Beauveria bassiana SAN01. The optimization of the juice clarification process led to 137% improvement in clarification compared to control, under optimal conditions of 39.37 U/mL enzyme load, 36.87°C temperature and 2.75 h treatment time. …”
Get full text

Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy by Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi, Francesco Saccoliti

“…Besides highlighting new potential drug targets, PAL can provide valuable information on efficacy and liabilities of small molecules at the molecular level, which could be exploited to greatly facilitate the rational optimization of compounds in terms of potency and safety. …”
Get full text

Ecosystem services value for water provisioning in the Shule River Basin of northwestern China: Spatial and temporal evolution and drivers from 2000 to 2022 by Peng Shi, Dongmei Zhou, Jing Jiang, Jing Ma, Xiaoyan Zhu, Jun Zhang, Zihe Li, Qinghan Dong

“…This provides an important reference for the optimization of ecosystem services in the basin and the scientific allocation of water resources. …”
Get full text

Solar‐Driven Hydrogen Peroxide Production via BiVO4‐Based Photocatalysts by Hui Ling Tan, Casandra Hui Teng Chai, Jerry Zhi Xiong Heng, Quyen Vu Thi, Xuelian Wu, Yun Hau Ng, Enyi Ye

“…An overview of fundamental principles, performance assessment methodologies, photocatalyst and photoelectrode development, and optimization of reaction conditions is provided. While diverse strategies, such as heterojunction, doping, crystal facet engineering, cocatalyst loading, and surface passivation, have proven effective in enhancing H2O2 generation, this review offers insights into their similar and distinct implementations within the PS and PEC systems. …”
Get full text

Unlocking the link: predicting cardiovascular disease risk with a focus on airflow obstruction using machine learning by Xiyu Cao, Jianli Ma, Xiaoyi He, Yufei Liu, Yang Yang, Yaqi Wang, Chuantao Zhang

“…For the general population, the XGBoost model was selected as the optimal model for predicting CVD risk (AUC = 0.7508, AP = 0.3186). …”
Get full text

BSG-WSL: BackScatter-guided weakly supervised learning for water mapping in SAR images by Kai Wang, Zhongle Ren, Biao Hou, Weibin Li, Licheng Jiao

“…Then, a morphological pseudo-label optimization algorithm is designed to employ CAMs to generate high-quality pseudo-labels. …”
Get full text

Policy instrument terms in patriotic health campaign documents issued by Chinese national government agencies from 1952 to 2023: a quantitative textual analysis by Yuanyuan LA, He ZHU, Qiqi WANG, Hongyan YAO, Xiaoyun LIANG

“…ObjectiveTo analyze the historical development and policy structure of China′s Patriotic Health Campaign policy, in order to provide theoretical, methodological and empirical references for the optimization of relevant policies. MethodsWe collected documents relevant to the Patriotic Health Campaign issued by Chinese national government agencies from 1952 to 2023 from relevant government portals, such as the State Council and the National Health Commission, as well as from Peking University′s Fabao and Legal Star databases. …”
Get full text

多层组合回转筛的动力学仿真分析 Dynamic simulation analysis of multilayer combined rotary screen by 张野，张超，张昊晨，刘海芃，高涛 ZHANG Ye, ZHANG Chao,ZHANG Haochen, LIU Haipeng, GAO Tao

“…To provide a reference for the body design optimization and operational debugging of multilayer combined rotary screen,the dynamic model of large-yield multilayer combined rotary screen was theoretically analyzed, the motion equation and dynamic parameters of the screen body were derived, then the dynamic modeling simulation was carried out through virtual prototyping technology. …”
Get full text

A Systematic Review of Maternal and Child Health Policies in Addressing Stunting: Trends and Challenges by Pratiwi Ramlan, Phill Sukri, Muh. Tang Abdullah, Muhammad Akmal Ibrahim, Jamaluddin Ahmad, Khaeriyad Adri

“…Implementing regulatory frameworks that mandate intersectoral collaboration between health, education, and agriculture sectors can enhance policy coherence and resource optimization. Furthermore, adopting performance-based incentives for local health agencies may encourage more effective policy implementation and service delivery.…”
Get full text

Sintering temperature dependence of microstructure evolution and compression performance of a novel circular Al honeycomb fabricated via powder sintering by Zhigang Xu, Enpeng Guo, Dayong Shen, Zhi Yang, Chong Xie, Jian Peng, Qiang Shen, Chuanbin Wang

“…The honeycomb sintered at 600 °C, in general, exhibited the optimal mechanical properties, with a plateau stress of 63.2 MPa. …”
Get full text

Comparative study on perovskite solar cells using P_ZnO, Al_ZnO and In_ZnO as ETMs by SCAPS-1D by Meriem Kerara, Abdelkrim Naas, Khalid Reggab

“…For the In_ZnO ETL, this optimization was accomplished at 300K working temperature. …”
Get full text

Prediction of Groundwater Level Based on the Integration of Electromagnetic Induction, Satellite Data, and Artificial Intelligent by Fei Wang, Lili Han, Lulu Liu, Yang Wei, Xian Guo

“…Fortunately, soil salinity and soil moisture may provide an optimized solution for GWL prediction based on the application of apparent conductivity (ECa, mS/m) using electromagnetic induction (EMI). …”
Get full text

LC-MS-Based Global Metabolic Profiles of Alternative Blood Specimens Collected by Microsampling by Marlene N. Thaitumu, Daniel Marques De Sá e Silva, Philippine Louail, Johannes Rainer, Glykeria Avgerinou, Anatoli Petridou, Vassilis Mougios, Georgios Theodoridis, Helen Gika

“…An extraction solvent optimization study was first performed on the three devices before the main study, which compared the global metabolic profiles of the four extracts (three BµS devices and plasma). …”
Get full text

Pinglu Canal Construction and Its Impact on Wildlife Habitat Connectivity: A Multi-Species Network Analysis and Ecological Restoration Strategy by Yuan Cao, Kai Su, Yongfa You, Xuebing Jiang, Chuang Li, Junjie Chen

“…Through complex network analysis, we assess habitat connectivity before and after the canal’s construction, as well as after implementing habitat optimization strategies. The results indicate that, following the completion of the Pinglu Canal, the wildlife habitat area decreased by 516.47 square kilometers, accounting for 5.79% of the total area, and the number of wildlife migration corridors decreased from 279 to 223, with a total decline of 56. …”
Get full text

A holistic exploration of porous asphalt mixtures: From durability and permeability to low-temperature and functional properties by Yue Zhou, Zhiqiang Cheng, Xiaoguang Zheng, Tao Wang, Xiaoliang Wu, Xiaoxiao Yu, Shengjia Xie

“…The study concludes by proposing improvement measures and optimization suggestions for porous asphalt mixtures, providing valuable references for future research and applications. …”
Get full text

Deep-Learning-Driven Insights into Nitrogen Leaching for Sustainable Land Use and Agricultural Practices by Caixia Hu, Jie Li, Yaxu Pang, Lan Luo, Fang Liu, Wenhao Wu, Yan Xu, Houyu Li, Bingcang Tan, Guilong Zhang

“…However, the performance improved significantly after integrating the four models with Bayesian optimization (all models had R² > 0.56), which realized quantitative prediction capabilities for nitrate leaching loss concentrations. …”
Get full text

Colorectal cancer detection with enhanced precision using a hybrid supervised and unsupervised learning approach by Akella S. Narasimha Raju, K. Venkatesh, Ranjith Kumar Gatla, Eswara Prasad Konakalla, Marwa M. Eid, Nataliia Titova, Sherif S. M. Ghoneim, Ramy N. R. Ghaly

“…A good balance between performance and generalization shall be done by hyperparameter optimization-heavy learning rates; dropout rates and overfitting shall be suppressed effectively. …”
Get full text

Aptamer-Conjugated Multi-Quantum Dot-Embedded Silica Nanoparticles for Lateral Flow Immunoassay by Kwanghee Yoo, Hye-Seong Cho, Jaehi Kim, Minsup Shin, Jun-Sik Chu, Sohyeon Jang, Han-Joo Bae, Heung Su Jung, Homan Kang, Bong-Hyun Jun

“…In this study, we prepared QD²@PEG@Aptamer, an aptamer conjugated with QD² using succinimidyl-[(N-maleimidopropionamido)-hexaethyleneglycol]ester, which is 130 times brighter than single QDs, for detecting carbohydrate antigen (CA) 19-9 through LFIA. For LFIA optimization, we determined the optimal conditions as a 1.0:2.0 × 10⁻² ratio of polyethylene glycol (PEG) to aptamer by adjusting the amounts of PEG and aptamer, phosphate-buffered saline containing 0.5% Tween^® 20 as a developing solution, and 0.15 μg NPs by setting the NP weight during development. …”
Get full text

Quantitative Analysis of Energy Storage Demand in Northeast China Using Gaussian Mixture Clustering Model by Yiwen Yao, Yu Shi, Jing Wang, Zifang Zhang, Xin Xu, Xinhong Wang, Dingheng Wang, Zilai Ou, Zhe Ma

“…This paper analyzes power supply data from Northeast China and models the stochastic characteristics of new energy generation. A joint optimization model for energy storage and thermal power is developed to optimize power allocation for peak shaving and frequency regulation at minimal cost. …”
Get full text

Clinical application of third-generation dual-source CT-based dynamic imaging reconstruction for pulmonary embolism imaging by Kai Liao, Biao Ye, Xi Li, Wei Liu, Tongtong Jia, Zongbao Han, Ziyi Liang, Yongli Duan, Xiaoli Sun, Jianmei Zhang, Rengui Wang, Jiao Gong

“…Abstract Background To evaluate the clinical diagnostic value of third-generation dual-source CT for pulmonary embolism, focusing on the optimization of dual-source CT scanning with dynamic reconstruction in acute pulmonary embolism (PE) and various imaging manifestations. …”
Get full text