Dynamic selectout and voting-based federated learning for enhanced medical image analysis by Saeed Iqbal, Adnan N Qureshi, Musaed Alhussein, Khursheed Aurangzeb, Atif Mahmood, Saaidal Razalli Bin Azzuhri

“…In certain situations, traditional FL techniques like FedProx and federated averaging, which depend on data size to weight contributions, might not be the optimal choice. In order to improve parameter aggregation and client selection unpredictability and increase the model’s adaptability to imbalanced and heterogeneous datasets, our proposed FedVoteNet model introduces SelectOut techniques based on voting methodology. …”
Get full text

Twenty-four weeks of combined training in different environments, aquatic and land, in the type 2 diabetes management (Aquatic and Land Exercise for Diabetes -ALED): protocol of a... by Larissa dos Santos Leonel, Ingrid Alessandra Victoria Wolin, Angélica Danielevicz, Mabel Diesel, Marina Isolde Constantini, João Batista de Oliveira Junior, Allana Andrade Souza, Thaís Reichert, João Gabriel Silveira-Rodrigues, Danusa Dias Soares, Marcelo Fernando Ronsoni, Simone Van De Sande Lee, Alex Rafacho, Guilherme Fleury Fina Speretta, Karla Siqueira Lottermann, Josefina Bertoli, Alexandre Pastoris Muller, Aline Mendes Gerage, Cíntia de La Rocha Freitas, Rodrigo Sudatti Delevatti

“…Moreover, this could support the development of intervention strategies to optimize the T2D management. Trial registration Brazilian Clinical Trial Registry (ReBEC) RBR-10fwqmfy. …”
Get full text

Nonlinear water stress response functions can improve the performance of the DSSAT-CERES-Wheat model under water deficit conditions by Ning Yao, Yingnan Wei, Kunhao Jiang, Jian Liu, Yi Li, Hui Ran, Tehseen Javed, Hao Feng, Qiang Yu, Jianqiang He

“…This study assesses the performance of modified water stress response functions stepwise. Optimal parameters for these functions were identified, with the smallest RMAE and RRMSE observed at specific parameter values for different curve types. …”
Get full text

Tracheostomy Practice in the Italian Intensive Care Units: A Point-Prevalence Survey by Raffaele Merola, Maria Vargas, Filippo Sanfilippo, Marco Vergano, Giovanni Mistraletti, Luigi Vetrugno, Gennaro De Pascale, Elena Giovanna Bignami, Giuseppe Servillo, Denise Battaglini

“…The high prevalence and notable complication rates emphasize the urgent need for standardized clinical protocols aimed at optimizing patient outcomes and minimizing adverse events. …”
Get full text

Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial by Jordan M. Cloyd, MD, Rakhsha Khatri, BA, Angela Sarna, BS, Lena Stevens, PhD, Victor Heh, PhD, Mary Dillhoff, MD, Alex Kim, MD, Timothy M. Pawlik, MD, PhD, MPH, Aslam Ejaz, MD, Sharla Wells-Di Gregorio, PhD, Erin Scott, MD, Sachin S. Kale, MD

“…Given the unique and complex care needs of this patient population, additional research is needed to optimize supportive care strategies.…”
Get full text

Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa by W M Simmonds, Y Awuku, C Barrett, M Brand, K Davidson, D Epstein, E Fredericks, S Gabriel, S Grobler, C Gounden, L Katsidzira, V J Louw, V Naidoo, C Noel, E Ogutu, N Ramonate, N Seabi, M Setshedi, J Van Zyl, G Watermeyer, C Kassianides

“…Integration of the recommendations is intended to promote optimal evaluation and management of patients with ID, regardless of the presence of anaemia. …”
Get full text

Saline water concentration determines the reduction pathway for oat phosphorus absorption by Tong Liu, Lihua Xia, Xinliang Dong, Jintao Wang, Xiaojing Liu, Hongyong Sun, Yunying Fang

“…This study reveals the effects of saline water irrigation on soil and crop phosphorus availability, providing valuable insights for optimizing saline water use and enhancing phosphorus availability in agricultural systems.…”
Get full text

Estimation of chlorophyll-a in uncrewed aircraft systems imagery using autonomous surface vessel data with machine learning algorithms and feature selection techniques by Mohammad Shakiul Islam, Padmanava Dash, Abduselam M. Nur, Hafez Ahmad, Rajendra M. Panda, Jessica S. Wolfe, Gray Turnage, Lee Hathcock, Gary D. Chesser, Jr, Robert J. Moorhead

“…Two feature selection techniques—Sequential Backward Floating Selection and Exhaustive Feature Selection—were employed to identify the optimal subset of variables. These techniques reduced the original d-dimensional feature space to a k-dimensional space by iteratively evaluating all possible feature combinations and selecting those that achieved the highest R2 scores for each ML algorithm. …”
Get full text

Insights in biomarkers complexity and routine clinical practice for the diagnosis of thyroid nodules and cancer by Maria de Lurdes Godinho de Matos, Mafalda Pinto, Ana Gonçalves, Sule Canberk, Maria João Martins Bugalho, Paula Soares

“…More studies with larger series are needed to optimize their use in routine practice. Additionally, the improvement of new techniques, such as liquid biopsy and/or artificial intelligence, may be the future for a better understanding of molecular biomarkers in thyroid nodular disease.…”
Get full text

Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Future studies should focus on elucidating the precise molecular mechanisms, optimal dosing strategies, and potential synergistic effects of CLO with other therapeutic agents.…”
Get full text

Novel Drug Delivery Particles Can Provide Dual Effects on Cancer “Theranostics” in Boron Neutron Capture Therapy by Abdul Basith Fithroni, Haruki Inoue, Shengli Zhou, Taufik Fatwa Nur Hakim, Takashi Tada, Minoru Suzuki, Yoshinori Sakurai, Manabu Ishimoto, Naoyuki Yamada, Rani Sauriasari, Wolfgang A. G. Sauerwein, Kazunori Watanabe, Takashi Ohtsuki, Eiji Matsuura

“…Here we present in vivo and ex vivo studies with human pancreatic cancer (AsPC-1) cells to find therapeutically optimal formulas and the appropriate treatment conditions for these particles. …”
Get full text

Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…Functional assays, including glucose tolerance tests and insulin tolerance tests, were optimized for individual axolotls. To assess pancreatic gene function, Pdx1 mutants were generated using CRISPR/Cas9-mediated gene editing, and their effects on pancreatic morphology, endocrine cell populations, and glucose homeostasis were analyzed.ResultsThe axolotl pancreas contains all known pancreatic cell types and develops from dorsal and ventral buds. …”
Get full text

Relationship between obesity indicators and hypertension–diabetes comorbidity among adults: a population study from Central China by Li Li, Ling Li, Ying Wang, Wenwen Wu, Xiaodong Tan, Fen Yang, Jinru Yang, Yifan Wu, Donghan Sun, Ziling Ni, Yaofei Xie

“…Females should focus on maintaining an optimal WHtR earlier.…”
Get full text

Antithrombotic therapy for a case report of acute myocardial infarction after laparoscopic radical cystectomy by Zilong Wang, Zilong Wang, Zilong Wang, Zilong Wang, Huisheng Yuan, Junhao Chu, Shishuai Duan, Zhihui Zhang, Changze Song, Muwen Wang

“…Therefore, the necessity and optimal strategy for anticoagulation therapy in patients with acute myocardial infarction following radical cystectomy remains a subject of ongoing debate. …”
Get full text

Preparation of oat galactolipid and anti-liver cancer effects of oat galactolipid–modified curcumin-loaded liver targeting vesicle by Huiying Ren, Nuo Chen, Yanqing Liu, Meimei Wu, Meimei Wu, Meimei Wu, Jingsong Yan, Jingsong Yan, Jingsong Yan, Mingxiang Chang, Mingxiang Chang, Mingxiang Chang, Hanmin Li, Hanmin Li, Hanmin Li

“…The morphology of the GCLTV was spherical, with an average particle size of 64.47 nm and average potential of −19.73 mV. The optimal proportion of galactolipids in the GCLTVs was selected as 30%. …”
Get full text

Application of metagenomic next-generation sequencing in the diagnosis of post-stroke infections: a case series study using multiple sample types by Xiaopu Chen, Yong Liang, Wei Yang, Wenzhen He, Zhiqiang Xing, Shunxian Li, Shaoyu Cai, Jiping Fu, Xiaotang Peng, Manli Chen, Jiaming Wu

“…Future research should focus on optimizing mNGS protocols, integration it with convertional diagnostic tools, and evaluating its cost-effectiveness and clinical impact through larger, multicentric studies.…”
Get full text

How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach by Qian Bai, Qian Bai, Lieyu Huang, Yan Guo, Xin Xu, Zhouyixin Zhang, Yuan Wang, Hao Chen, Ying Bian, Ying Bian

“…On the other side, the ratio of older population, the sex ratio and the Nitrogen Oxides emission volume had positive impacts on technical efficiency with variations in coefficient magnitude across different geographic areas.ConclusionThe efficiency of specialized public health facilities has not achieved the optimal status, particularly in terms of the pure technical efficiency. …”
Get full text

Blood-based prognostic scores and early dynamics under immunotherapy to select patients with metastatic solid tumors for continuing immune check-point inhibition: a prospective lon... by Javier García-Corbacho, Alberto Indacochea, Iván Victoria, Débora Moreno, Laura Angelats, Azucena E. González Navarro, Laura Mezquita, Fara Brasó-Maristany, Patricia Galván, Begoña Mellado, Nuria Viñolas, Tamara Sauri, Miquel Nogué, Barbara Adamo, Joan Maurel, Estela Pineda, Lydia Gaba, Oscar Reig, Neus Basté, Esther Sanfeliu, Manel Juan, Aleix Prat, Francesco Schettini

“…Abstract Introduction Immune check-point inhibitors (ICI) were a major breakthrough in cancer care, but optimal patient selection remains elusive in most tumors. …”
Get full text

Biochar Application and Mowing Independently and Interactively Influence Soil Enzyme Activity and Carbon Sequestration in Karst and Red Soils in Southern China by Wenjia Luo, Daniel F. Petticord, Shiwen Zhu, Shaowu Zhu, Yuanlong Wu, Xun Yi, Xinyue Wang, Yili Guo, Xuxin Song

“…This study highlights biochar as an effective tool for enhancing SOC stability in karst grasslands, particularly in acidic soils, and suggests that integrating biochar into mowing regimes may optimize carbon sequestration while reducing fire risk. …”
Get full text

Physiological and productivity responses of Tahiti acid lime grafted onto dwarfing rootstocks under different planting and mulching practices by Ana Júlia Borim de Souza, Mariângela Cristofani-Yaly, Patrícia Marluci da Conceição, Fernando Trevizan Devite, Marinês Bastianel, Paulo Vitor Sanches Romero, Pedro Henrique Barrio Padilha, Fernando Alves de Azevedo

“…This study highlights the importance of selecting appropriate scion-rootstock combinations and adopting sustainable management practices to improve resilience to environmental stress and optimize fruit yield and quality.…”
Get full text