Approach to shoulder instability: a randomized, controlled trial by Julien Caron, MD FRCSC, Kellen Walsh, MD FRCSC, Tinghua Zhang, MSc, Rashed AlAhmed, MBChB MSc FRCSC, Peter B. MacDonald, MD FRCSC, Cristina Bassi, MD, J Whitcomb Pollock, MD FRCSC MSc, Katie McIlquham, BSc, Peter Lapner, MD FRCSC

“…The instability severity index Score (ISI score) is a point-based algorithm that may be used to assist clinicians in selecting the optimal treatment approach, but its efficacy compared with a traditional treatment algorithm has not been previously validated. …”
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Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for... by Anna Ugalde, Richard W. Tothill, Stephen Quinn, Hui-Li Wong, Owen Prall, Catherine Mitchell, Nilmini Wickramasinghe, Clare Fedele, Natalie Richards, Elizabeth Todio, Cindy Bryant, Louisa G. Collins, Sarah McLean, Hyun Soo Ko, Tim Akhurst, Christopher Steer, Bo Gao, Mark Wong, Chloe Georgiou, Narayan Karanth, Anna Kuchel, Louise Nott, Shamsudheen Padinharakam, Mark Shackleton, Ian M. Collins, Madhu Singh, Rachel Wong, Zee Wan Wong, Alexis Butler, Tharani Sivakumaran, Penelope Schofield, Linda Mileshkin

“…This trial aims to implement and evaluate an optimal model of care for people presenting with MUO to reduce time to diagnosis, improve patient experiences and reduce healthcare costs. …”
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Bayesian network for predicting mandibular third molar extraction difficulty by Tian Meng, Zhiyong Zhang, Xiao Zhang, Chao Zhang

“…By integrating these patient-specific risk factors across the entire surgical process, this model could be used during preoperative planning to identify high-risk cases and to optimize resource allocation; during intraoperative management to tailor surgical techniques; and during postoperative follow-up to establish targeted follow-up protocols for high-risk patients. …”
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Validation of insurance claims data on aetiology, surgical type and prosthesis for isolated valve surgery: a retrospective observational surgery by Shao-Wei Chen, Victor Chien-Chia Wu, Pao-Hsien Chu, An-Hsun Chou, Chun-Yu Chen, Feng-Cheng Chang, Yi‐Hsin Chan, Chia-Pin Lin, Yu-Ting Cheng, Bo-Cheng Hou, Jo-Ting Huang

“…This study provides a potentially optimal framework for future research on valve diseases and surgeries using claims databases.…”
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Effects of Different Molasses Levels and Slow-Release Urea Combinations on Growth Performance, Serum Biochemistry, Rumen Fermentation, and Microflora of Holstein Fattening Bulls by Zhiyuan Xu, Shuaihong Li, Fangzhou Yu, Yinghao Huang, Tao Xie, Hanbing Bian, Longfei Lv, Yapeng Hu, Ruoran Tao, Caiyun Fan, Sijia Liu, Jianbo Cheng

“…In conclusion, the MMU was effective in improving the growth performance of fattening cows, optimizing rumen fermentation, reducing cost, and increasing profit, which is a nutritional strategy with great application value.…”
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The efficacy and safety of first-line monotherapies in primary therapy of invasive aspergillosis: a systematic review by Yan Chen, Yan Chen, Jiaojiao Zhao, Jiaojiao Zhao, Yifei Wang, Yifei Wang, Long Ge, Long Ge, Joey Sum-wing Kwong, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Shuimei Sun, Songsong Tan, Xiaoqing Lin, Rui He, Wenyi Zheng, Xiaosi Li, Jiaxing Zhang

“…Furthermore, the risk of AEs and SAEs was comparable for the three triazoles, but the risk of SAEs was significantly higher for D-AmB than others.ConclusionThe efficacy and safety of triazoles are more favorable than D-AmB in the primary therapy of IA, with ISA being the optimal choice.Systematic Review RegistrationPROSPERO CRD42023407632.…”
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Rapid and noninvasive assessment of adductor muscle performance through shell-closing strength of Zhikong scallop Chlamys farreri by Xiangyi Zeng, Zujing Yang, Mingyi Sui, Zhi Liu, Qiang Xing, Liping Hu, Liming Jiang, Zhenmin Bao, Xiaoting Huang

“…In this study, a rapid and noninvasive method was developed to quantify SCS with four indicators including total force (TF), time of shell closing (TSC), average force (AF), and maximum force (MF) using a self-developed force gauge device. The optimal measurement time and distance for SCS were three minutes and 0.75 cm, respectively. …”
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Humic acid improves water retention, maize growth, water use efficiency and economic benefits in coastal saline-alkali soils by Ge Li, Yuyang Shan, Weibo Nie, Yan Sun, Lijun Su, Weiyi Mu, Zhi Qu, Ting Yang

“…Furthermore, the function analysis of WUE and ∆NP identified the optimal HA application rates as 193.5 kg ha−1 and 182.3 kg ha−1, respectively. …”
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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

“…Introduction Emergency department (ED)-initiated palliative care has been shown to improve patient-centred outcomes in older adults with serious, life-limiting illnesses. However, the optimal modality for providing such interventions is unknown. …”
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Identifying joint association between body fat distribution with high blood pressure among 7 ∼ 17 years using the BKMR model: findings from a cross-sectional study in China by Manman Chen, Xijie Wang, Yanhui Li, Di Gao, Ying Ma, Tao Ma, Yi Zhang, Li Chen, Jieyu Liu, Qi Ma, Mengjie Cui, Xinxin Wang, Tongjun Guo, Wen Yuan, Yanhui Dong, Jun Ma

“…We recommend that children of different sexes and weight statuses be provided with body-part-specific exercise recommendations for optimal chronic disease prevention and control benefits.…”
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Progress in phase field research of dead lithium in lithium batteries by Jing LIU, Huiyi CHEN, Huiyu LIU, Shu LI

“…These factors can regulate the deposition form of lithium to a certain extent and slow down or avoid the formation of lithium dendrites and dead lithium. By optimizing these factors, researchers can better control the deposition morphology of lithium, alleviating or even avoiding the formation of lithium dendrites and dead lithium. …”
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Improving Patient Outcomes in mTBI: The Role of Integrated Nursing Interventions in the Emergency Department by Feng T, Zhao P, Wang J, Du X, Ai M, Yang J, Li J

“…These interventions, which include early assessment, timely intervention, patient education, and collaborative care, are essential for optimizing TBI management. The high predictive value of these interventions further underscores their importance in emergency care. …”
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Urinary human papillomavirus DNA as an indicator of gynaecological infection in young women in Schistosoma and HIV endemic South Africa by P. Pillay, H. N. Galappaththi-Arachchige, M. Taylor, B. Roald, B. Roald, E. F. Kjetland, E. F. Kjetland

“…There was no statistical association between urinary schistosomiasis and HPV or with any atypia.ConclusionUrine has the potential of being optimized as an alternative and possibly more acceptable sample for HPV detection among young adolescent populations at risk in comparison to CVL samples. …”
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Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, follo... by G. Menardi, A. Castellino, C. Castellino, M. E. Bersia, E. Grande, G. Fraternali, M. Massaia, C. Fruttero

“…It underscores the value of anakinra as a potential corticosteroid-sparing therapy for immune effector cell-associated neurotoxicity syndrome and raises the need for further research to optimize the management of immune effector cell-associated hematotoxicity and associated complications. …”
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Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…Conclusion Our meta-analysis suggests that PEDD is a potentially effective and safe intervention for SI. Optimizing antibiotic discontinuation and postoperative care strategies may contribute to reducing reoperation rate. …”
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Enhancing healthcare utilization and reducing preventable hospitalizations: exploring the healthcare-seeking propensity of patients with non-communicable diseases in Rural China by Yanqiu Hou, Wenyu Li, Shangai Li, Linxuan Chen, Jiayu An, Shan Lu

“…Abstract Objective Understanding healthcare-seeking propensity is crucial for optimizing healthcare utilization, especially for patients with chronic conditions like hypertension or diabetes, given their substantial burden on healthcare systems globally. …”
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Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow by Liao X, Liu H, Li Y, Zhang W, Dai Q, Wei H, Zhou J, Xie X, Zhou H

“…These findings offer vital guidance for optimizing personalized treatment of IBD, emphasizing the importance of carefully managing the timing and dosage of α-MSH for its effective clinical application.Keywords: IBD, α-MSH, hematopoietic stem cells, neutrophils, inflammation…”
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A detector based on a multiscale fusion pyramid focus network for catenary support components by Xinyu ZHU, Haorui CUI, Yang SONG

“…The separable residual pyramid aggregation module (SRPAM) was designed to optimize multi-scale feature extraction, expand the receptive field, and address multi-scale issues in CSC detection. …”
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Controlled bottom-up synthesis and characterization of crystalline and amorphous lead(II) coordination polymers: Sonochemical methods, structure–property relationship, and photocat... by Saeedeh Ebad Sichani, Mohammad Jaafar Soltanianfard, Alison Zamanpour, Payam Hayati, Jan Janczak, Zahed Karimi-Jaberi

“…Calculation of the band gap of synthesized polymers was conducted using the Tauc diagram (based on the DRS results). During optimal conditions of C0 = 0.6 mg L1, pH = 7, and irradiation time = 60 min, the maximum photodegradation efficiencies of methylene blue (MB) were observed for 1a and 2b_2. …”
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Pendekatan Bayes-HDSS dalam Menentukan Status Pantauan Gizi Balita by Riki Hisbullah, Muhammad Siddik Hasibuan

“…Bayes is used to diagnose disease and AHP and TOPSIS will be used to rank diseases in humans, including nutrition in children where until now the world's biggest problem is how to overcome malnutrition experienced by toddlers including stunting problems, where toddler growth  is not optimal. By using an Expert System and HDSS (namely AHP and TOPSIS) it is forbidden to calculate criteria that are symptoms in children, to produce a sequence of children who are the focus of monitoring. …”
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