Retention strategies for medical doctors in low- and middle-income countries (LMICs): are they effective? A scoping review by Norehan Jinah, Izzuan Khirman Adnan, Pangie Bakit, Ili Abdullah Sharin, Kun Yun Lee

“…Thus, a multifaceted, comprehensive approach is essential in producing sustainable health workforce development that ensures optimal health outcomes, especially for populations in underserved areas. …”
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Candida Bloodstream Infection: Changing Pattern of Occurrence and Antifungal Susceptibility over 10 Years in a Tertiary Care Saudi Hospital by Nawaf Alkharashi, Sameera Aljohani, Laila Layqah, Emad Masuadi, Waleed Baharoon, Hamdan AL-Jahdali, Salim Baharoon

“…Candida has emerged as one of the most important pathogens that cause bloodstream infection (BSI).Understanding the current Candida BSI trends, the dominant species causing disease and the mortality associated with this infection are crucial to optimize therapeutic and prophylaxis measures. Objectives. …”
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Problems and Barriers Related to the Use of AI-Based Clinical Decision Support Systems: Interview Study by Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik, Philipp Heinz, Marianne Tokic, Nina Timmesfeld, Frank Brunkhorst, Jürgen Wasem, Nikola Blase

“…They can be used as a basis for deriving solutions to optimize development, acceptance, and use of AI-based CDSSs. …”
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Experimental research on mechanical and impact properties of ceramsite prepared from secondary aluminum dross and municipal solid waste incineration ash by Wangze He, Yufei Yang, Xinghan Zhu, Jinzhong Yang, Yingjie Sun, Qifei Huang

“…Under these conditions, the optimal composition ratio of ceramsite is Si:Al = 3, and the ideal particle size is 0.5 cm. …”
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Outcome of Newborns with Tracheoesophageal Fistula: An Experience from a Rapidly Developing Country: Room for Improvement by Amal Al-Naimi, Sara G. Hamad, Abdalla Zarroug

“…Tracheoesophageal fistula (TEF) represents one of the most common congenital developmental malformations of the upper digestive tract. The optimal surgical management has several controversies, particularly in rapidly developing countries. …”
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Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity by R. Babu, Manokaran Veeramani, Wallepure Aadinath, Vignesh Muthuvijayan, Shailja Singh, Smita Srivastava

“…Bioprocess principles can be applied to develop sustainable methods for the commercial production of high-quality V. odorata plant biomass.MethodsTo this effect, the in vitro culture conditions of V. odorata were rationally optimized to increase the biomass production up to 21.7 ± 0.8 g DW L−1 in 12 days in shake flasks. …”
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Public Health Messaging on Twitter During the COVID-19 Pandemic: Observational Study by Ashwin Rao, Nazanin Sabri, Siyi Guo, Louiqa Raschid, Kristina Lerman

“…PHEs typically used positive emotional language across all issues (P<.001), expressing optimism and joy. Pseudoexperts often used negative emotions of pessimism and disgust, while limiting positive emotional language to origins and therapeutics (P<.001). …”
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Effects of epidural esketamine versus sufentanil on labor analgesia and postpartum depression: a retrospective cohort study by Kunyue Li, Ziqi Chai, Chunyun Deng, Guoying Niu, Xiaoyuan Geng, Yu Zhang, Yuxia Wang, Tao Wang

“…Further exploration of the optimal regimen and dosage of esketamine for epidural labor analgesia would be necessary.…”
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Optimalisasi Proses Klasifikasi Dengan Menambahkan Semantik Pada Kebutuhan Non-Fungsional Berbasis ISO/IEC 25010 by Lukman Hakim, Choirul Huda

“…Based on the problems in previous studies, it is necessary to optimize by adding semantics to the FSKNN method. The system used to identify NFRs consists of two stages. …”
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Coincidental or Connected: Synchronous Giant Gastric GIST and Malignant Colonic Polyp: A Case Report by Terukumar Chandrasekaran, Lim Li Yi, JJ Mah, RK Sriram, Nik Amin Sahid

“…Due to its rare occurrence and limited literature further GIST with another synchronous tumor must be conducted to help surgeons optimize patient management.…”
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Impact of Improved Sanitation Standard Operating Procedures on Microbial Populations at Three Tree Fruit Packing Facilities by M. Laura Rolon, Marysabel Mendez Acevedo, Priscilla Sinclair, Dumitru Macarisin, Luke F. LaBorde, Jasna Kovac

“…There is a need for the future work to focus on optimizing and validating the standard operating procedures, especially in the areas in which SSOPs were less effective, such as those covered with wax residues.…”
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The effectiveness analysis of traditional and new landscape indexes in indicating flood risk of watersheds from the perspective of source-sink landscapes: A case study of Changsha,... by Lingxuan Zhang, Sheng Jiao, Jie Lu

“…The findings offer an effective ecological approach for stormwater management and provide valuable insights for optimizing landscape spatial patterns. These results have significant implications for enhancing urban disaster resilience and informing planning efforts. …”
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Implementation of multidisciplinary team decisions on the management of complex bone and joint infections: an observational study by Jaap L.J. Hanssen, Henrica M.J. van der Linden, Martha T. van der Beek, Robert J.P. van der Wal, Marco F. Termaat, Mark G.J. de Boer, Henk Scheper

“…Reasons for non-implementation were disagreement by the treating surgeon with the MDT regarding the optimal treatment (n = 24, 23%), patient preference for a different treatment (n = 19, 18%), new clinical information not yet available during the MDT meeting that made the physician change management (n = 17, 16%) or unknown (n = 45, 43%). …”
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Blood Pressure in relation to 24-Hour Urinary Sodium and Potassium Excretion in a Uruguayan Population Sample by Paula Moliterno, Ramón Álvarez-Vaz, Matias Pécora, Leonella Luzardo, Luciana Borgarello, Alicia Olascoaga, Carmen Marino, Oscar Noboa, Jan A. Staessen, José Boggia

“…Many public health policies in Latin America target an optimized sodium and potassium intake. The aims of this study were to assess the sodium and potassium intake using 24-hour urinary analysis and to study their association with blood pressure in a Uruguayan population cohort using cluster analysis. …”
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Annual change in the distribution and landscape health of mangrove ecosystems in China from 2016 to 2023 with Sentinel imagery by Yuchao Sun, Mingzhen Ye, Bin Ai, Zhenlin Lai, Jun Zhao, Zhuokai Jian, Xinyan Qi

“…The research shows that compared to the combination model of PSPNet and DeepLabV3 with Resnet, the U-net+ResNet34 model gave the most optimal results in identifying mangroves. In addition, the F1-score of the model reached 0.843 when validated with the samples collected from the national mangrove dataset. …”
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Comparison of HCG Trigger versus Dual Trigger in Improving Pregnancy Outcomes in Patients with Different Ovarian Responses: A Retrospective Study by Ke Xu, Jinrong Wang, Shuangshuang Yang, Zhenjing Wang, Ning Hou, Mei Sun

“…Our objective was to evaluate the pregnancy outcomes in IVF-ET patients across different ovarian response groups, exploring the efficacy of the dual-trigger and single-trigger regimens to provide valuable insights for optimizing clinical strategies in the context of IVF-ET. …”
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Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer by Angelica Nogueira Rodrigues, Andreza Karine de Barros Almeida Souto, Diocésio Alves Pinto de Andrade, Larissa Müller Gomes, Sandra Satie Koide, Renata de Godoy e Silva, Bruno Batista de Souza, Juliana Doblas Massaro, Andréia Cristina de Melo, Andrea Morais Borges, Camila Giro, Carlos Augusto Vasconcelos de Andrade, Cesar Martins da Costa, Daniel Luiz Gimenes, Eduardo Caminha Bandeira de Mello, Fernanda Cesar de Oliveira, Frederico Müller de Toledo Lima, Gabriel Lima Lopes, Gustavo de Oliveira Bretas, Gustavo Guerra Jacob, Herika Lucia da Costa Silva, Juliana Ferrari Notaro, Lara Ladislau Alves, Marcos Veloso Moitinho, Mirian Cristina da Silva, Roberto Abramoff, Thais Amaral da Cunha Rauber, Rodrigo Dienstmann, Fernanda Christtanini Koyama

“…In this scenario, access to a validated diagnostic HRD test can optimize treatment selection and increase the effectiveness of the intervention.ObjectiveTo technically validate an in-house next-generation sequencing (NGS)-based HRD test, QIAseq Custom Panel (QIAGEN), by comparing it with the reference assay, MyChoice CDx® Plus HRD (Myriad Genetics), which is used in routine care.MethodsThis is a prospective cohort study conducted at the Oncoclínicas Precision Medicine (OCPM) laboratory using samples from patients with advanced or relapsed platinum-sensitive ovarian cancer eligible for HRD testing in a diagnostic clinical setting at Oncoclínicas and Co. …”
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Pharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> in Canine Cl... by Syed Al Jawad Sayem, Ga-Yeong Lee, Muhammad Aleem Abbas, Seung-Chun Park, Seung-Jin Lee

“…High-dose amoxicillin therapy is recommended to achieve optimal therapeutic outcomes for resistant SA, while slightly adjusted dosing can manage <i>S. pseudintermedius</i> infections. …”
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Green analysis of illicit drugs on banknote dust by Teresa Cecchi, Arianna Giuliani, Carlo Catini

“…A UHPLCHRMS system with ethanol as the organic modifier was used to develop and optimize the chromatographic method; a stable isotope labelled internal standard for each analyte was used to compensate matrix effects and possible losses. …”
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Alternative approaches for monitoring and evaluation of lymphatic filariasis following mass drug treatment with ivermectin, diethylcarbamazine and albendazole in East New Britain P... by Krufinta Bun, Benedict Mode, Melinda Susapu, Joyceline Salo, Catherine Bjerum, Michael Payne, Daniel Tisch, Makoto Sekihara, Emanuele Giorgi, Gary J Weil, Peter U Fischer, Leanne Robinson, Moses Laman, Christopher L King

“…Whether two rounds of MDA are necessary or sufficient and the optimal sampling strategies and endpoints for stopping MDA remain undefined.…”
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