Stress distribution in endodontically treated external cervical resorption lesions restored with MTA and biodentine – A finite element analysis by Mudita Manaktala, Sonali Taneja, Vidhi Kiran Bhalla

“…Further research is necessary to validate these findings and optimize treatment protocols for ECR.…”
Get full text

Development and validation of a nomogram for predicting cough variant asthma diagnosis by Jiao Min, Xiaomiao Tang, Di Zhang, Jin Yang, Fei Li, Wei Lei

“…The nomogram demonstrated good discrimination (AUC = 0.829) and calibration, with a sensitivity of 75.3% and specificity of 77.6% at the optimal cutoff. The C-index was 0.920, indicating excellent model performance. …”
Get full text

Early Intervention for Children With Developmental Disabilities and Their Families via Telehealth: Systematic Review by Yoomi Shin, Eun Ju Park, Anna Lee

“… BackgroundEarly intervention during the first 3 years of life is crucial for children with developmental disabilities to optimize developmental outcomes. However, access to such services is often limited by geographical distance and resource constraints. …”
Get full text

Generative spatial artificial intelligence for sustainable smart cities: A pioneering large flow model for urban digital twin by Jeffrey Huang, Simon Elias Bibri, Paul Keel

“…These transformative tools provide advanced capabilities to analyze complex urban systems, optimize resource management, and enable evidence-based decision-making. …”
Get full text

Dietary practice and associated factors among lactating mothers in Dangila District in the Awi Zone Amhara region Ethiopia, 2022: a cross-sectional study by Sileshi Mulatu, Getasew Mulatu, Azeb Gedif

“…Key stakeholders, including the Ministry of Health (MOH), Regional Health Bureaus (RHB), and health professionals, must work together to alleviate food insecurity, promote optimal family planning, and educate mothers on proper nutrition. …”
Get full text

Research on pipeline-type power frequency electromagnetic heating system and multi-layer winding based power regulation method by Feng Zhou, Longyun Liu, Zixuan Wang, Xin Tong, Yanping Liu

“…To further enhance the economic efficiency of the heating device, the magnetic induction strength of the core with different hollow sizes is investigated. From this, the optimal hollow radius of the core structure was determined, achieving a saving ratio of approximately 36.52 %. …”
Get full text

Exploring the Pathophysiology, Diagnosis, and Treatment Options of Multiple Sclerosis by Simone Lorenzut, Ilaria Del Negro, Giada Pauletto, Lorenzo Verriello, Leopoldo Spadea, Carlo Salati, Mutali Musa, Caterina Gagliano, Marco Zeppieri

“…Improving long-term outcomes for MS patients and optimizing disease treatment may be possible by utilizing immunology, genetics, and neuroimaging developments. …”
Get full text

Influence of quartz types on mechanical parameters in the early silurian Longmaxi shale, Sichuan Basin by Qin Zhang, Feng Liang, Qun Zhao, Wen Liu, Weiliang Kong, Wanli Gao, Xinyu Zhang, Guangyin Cai, Tianquan Qu, Zhen Qiu

“…When the quartz content falls between 52% and 85%, the ratio of DQ to BQ is optimal for fracture development coinciding with high BI values, which are most conducive to fracturing stimulation.…”
Get full text

Analytic and clinical validity of thyroid nodule mutational profiling using droplet digital polymerase chain reaction by Vincent L. Biron, Ashlee Matkin, Morris Kostiuk, Jordana Williams, David W. Cote, Jeffrey Harris, Hadi Seikaly, Daniel A. O’Connell

“…In addition to clinical protocol, an additional FNAB was obtained for ddPCR. Optimized ddPCR probes were used to detect mutations including HRASG12 V, HRASQ61K, HRASQ61R, NRASQ61R, NRASQ61K and BRAFV600E. …”
Get full text

Effect of perioperative esketamine use on emergency delirium in children undergoing tonsillectomy and adenoidectomy: a systematic review and meta-analysis of randomized controlled... by Junfeng Liu, Jinming Liu, Hong Sun, Xue Cheng, Chunhui Wang, Daoyun Lei, Chao Han

“…We also found that the use of esketamine reduced the length of stay in the post-anesthetic care unit (PACU) but had no effect on the time to extubation.ConclusionPerioperative use of esketamine could significantly reduce the incidence of ED in children undergoing tonsillectomy and adenoidectomy. However, the optimal dose and timing of esketamine administration for preventing ED remains to be explored.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?…”
Get full text

Effects of kelp phlorotannins on the growth, immunity, intestinal health and disease resistance against Vibrio splendidus of sea cucumber Apostichopus japonicus by Zhikai Zhang, Yan Chi, Yongheng Du, Feng Li, Ning Ma, Song Qin

“…Based on the growth and survival after challenge, the optimal dietary concentration of phlorotannins was 0.8 g kg−1 for sea cucumber.…”
Get full text

Examining the Leverage Effect, Dynamic Conditional Correlation, and Volatility Spillover Among Selected Indices of the Tehran Stock Exchange: Evidence from the ARMA-DCC-GJR-GARCH M... by Gholamhosein Golarzi, Seyed Ramin Abolfazli

“…Hence, based on the results revealing the presence of leverage effect, dynamic conditional correlation, and volatility contagion, investors and portfolio managers can use these findings to mitigate risks and optimize their portfolios.…”
Get full text

Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction by Yize Sun, Yize Sun, Haibin Zhao, Zheyi Wang

“…The purpose of this study is to determine the ingredients of PCF, further to probe the underlying mechanism for MI with depression.MethodsThe compounds of PCF were qualitatively identified by LC-MS/MS. The optimal dosage for lavage with the PCF solution in rats was determined to be 1 mL/100 g/day for a duration of 5 days. …”
Get full text

The analysis of factors influencing patient choice of healthcare providers between tertiary hospitals and community clinics by Silin Wu, Silin Wu, Zhaoxia Lei, Tinglian Liu, Lan Chen, Yang Qin

“…The tiered healthcare delivery system aims to optimize resource allocation and strengthen primary care, yet patient preferences for tertiary hospitals hinder its effective implementation. …”
Get full text

A recurrent YOLOv8-based framework for event-based object detection by Diego A. Silva, Kamilya Smagulova, Ahmed Elsheikh, Mohammed E. Fouda, Ahmed M. Eltawil

“…ReYOLOv8 incorporates a low-latency, memory-efficient method for encoding event data called Volume of Ternary Event Images (VTEI) and introduces a novel data augmentation technique based on Random Polarity Suppression (RPS) optimized for event-based sensors and tailored to leverage the unique attributes of event data. …”
Get full text

Development of a metabolome-based respiratory infection prognostic during COVID-19 arrival by John I. Robinson, Laura R. Marks, Andrew L. Hinton, Jane A. O'Halloran, Charles W. Goss, Peter J. Mucha, Jeffrey P. Henderson

“…ABSTRACT In a new respiratory virus pandemic, optimizing allocation of scarce medical resources becomes an urgent challenge. …”
Get full text

Influence of Drying Methods on the Morphological Features, Microstructural Properties, and Antioxidant Performance of <i>Floccularia luteovirens</i>: A Metabolomic Analysis by Mengjun Xiao, Tao Wang, Chuyu Tang, Min He, Xiaojian Pu, Tingjing Zhao, Yuling Li

“…This research clarifies how different drying techniques impact the metabolites or metabolic pathways of <i>F. luteovirens</i>, identifying the mechanisms that influence its quality and providing a reference for optimizing its processing and storage.…”
Get full text

Association of workforce participation with depression among US older adults: results from NHANES 2005–2018 by Zhenyu Sun, Yi Wang, Xi Chen, Dongfu Qian

“…Conclusions Regular daytime working was positively related to decreased depression risk among US older adults, and the suggested optimal working hours were 25 to 35 per week. Policymakers should appreciate the potential value of moderate workforce participation to mental health among older adults.…”
Get full text

Micro-Electro Nanofibrous Dressings Based on PVDF-AgNPs as Wound Healing Materials to Promote Healing in Active Areas by Liu T, Xie F, Geng L, He R, Sun M, Ni T, Xu P, Xing C, Peng Y, Chen K, Fang Y

“…By designing a micro-electro-Nanofiber dressing composed of piezoelectric polyvinylidene fluoride (PVDF) integrated with antimicrobial silver nanoparticles (AgNPs), this research aims to address the dual challenges of promoting effective wound healing and maintaining joint mobility.Methods: Herein, we developed a novel micro-electro-Nanofiber dressing using electrospinning technology, incorporating polyvinylidene fluoride (PVDF) with silver nanoparticles (AgNPs). The optimized PVDF-AgNPs Nanofiber dressings exhibited strong piezoelectric effects suitable for joint wounds.Results: In vitro experiments demonstrated that the dressing effectively promoted fibroblast migration and collagen synthesis. …”
Get full text

A global review of national guidelines of post‐exposure prophylaxis for the prevention of HIV by Marcus Maisano, Daniel Tran, Virginia Macdonald, Rachel C. Baggaley, Nathan Ford, Cheryl C. Johnson, Ying Zhang, Jason J. Ong

“…There are opportunities for countries to update and optimize guidance to consider ways to improve the accessibility of PEP. …”
Get full text