Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…Recent advances in virtual reality technology may offer promising solutions, although the optimal approach to enhance social participation among stroke survivors is yet to be determined. …”
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Diagnostic efficacy of dual-energy CT virtual non-calcium technique in the diagnosis of bone marrow edema of sacroiliac joints in ankylosing spondylitis by Hongyue Lu, Zhi Li, Ziheng Liang, Yuqi Liu

“…Based on the receiver operating characteristic curve analysis, the area under the curve for the iliac and sacral surfaces were 0.90 and 0.89, respectively. The optimal CT cutoff values were − 57.4 Hu and − 56.8 Hu, with corresponding sensitivities of 92.5% and 86.4% and specificities of 90.7% and 87.8%. …”
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Impact of regionalisation and case-volume on neonatal and perinatal mortality: an umbrella review by Jochen Schmitt, Stefanie Deckert, Mario Rüdiger, Felix Walther, Denise Bianca Küster, Anja Bieber, Jürgen Malzahn

“…In the long term, an international, uniformly conceived and defined perinatal database could help to provide evidence-based recommendations on optimal strategies to regionalise perinatal care.PROSPERO registration number CRD42018094835.…”
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Voriconazole Pharmacokinetics Administered at 4 mg/kg IM and IV in Nursehound Sharks (<i>Scyliorhinus stellaris</i>) Under Human Care by Daniela Cañizares-Cooz, Daniel García-Párraga, Sonia Rubio-Langre, Teresa Encinas, Pablo Morón-Elorza

“…Moreover, further research on the susceptibility of fungal pathogens affecting elasmobranchs is needed to establish an optimal dosing regimen for IM voriconazole in the treatment of mycosis in sharks.…”
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Effects of poultry by-product meal and complete replacement of fish oil with alternative oils on growth performance and gut health of rainbow trout (Oncorhynchus mykiss): a FEEDNET... by Imam Hasan, Simona Rimoldi, Biagina Chiofalo, Marianna Oteri, Micaela Antonini, Rosangela Armone, Violeta Kalemi, Laura Gasco, Genciana Terova

“…Conclusions The FEEDNETICS™ application enhances our ability to optimize feeding strategies and improve production efficiency in the aquaculture industry. …”
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Comparative evaluation of various DNA extraction methods and analysis of DNA degradation levels in commercially marketed Chestnut rose juices and beverages by Yongchao Ren, Yunlong Ma, Yanqi Li, Yun Song, WeiWei Zhao, Xuncai Huang, Danmin Yu, Jian Li, Zuogang Xu, Wenjun Zhao

“…This study aimed to optimize and compare four DNA extraction methods for Chestnut rose juices and beverages. …”
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Configurable Multi-Layer Perceptron-Based Soft Sensors on Embedded Field Programmable Gate Arrays: Targeting Diverse Deployment Goals in Fluid Flow Estimation by Tianheng Ling, Chao Qian, Theodor Mario Klann, Julian Hoever, Lukas Einhaus, Gregor Schiele

“…These results confirm the workflow’s ability to identify optimal FPGA accelerators tailored to specific deployment requirements, achieving a balanced trade-off between precision, inference latency, and energy efficiency.…”
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Agent-Based Adaptive Dynamic Round Robin (AADRR) Scheduling Algorithm by Zafar Iqbal Khan, Muzafar Khan, Syed Nasir Mehmood Shah

“…To validate the effectiveness of the AADRR algorithm, we performed a comparative performance analysis with twelve other algorithms, including five traditional CPU scheduling algorithms and seven advanced job scheduling techniques, demonstrating optimal performance results. In our experiments, synthetic workload traces were generated using the Monte Carlo probability distribution method, which is scientifically recommended for creating diverse workload traces. …”
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Design and Development of a Web‐Based Registry for Outpatient Rehabilitation: A Delphi Multi‐Disciplinary, Expert Consensus Study by Seyyedeh Fatemeh Mousavi Baigi, Masoumeh Sarbaz, Davood Sobhani‐Rad, Salman Nazary‐Moghadam, Javad Heravian Shandiz, Kosar Ghaddaripouri, Reyhane Norouzi Aval, Khalil Kimiafar

“…The registry was intended to enhance assessment, guide optimal care, and provide value‐based and evidence‐based rehabilitation management for patients. …”
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Unveiling new therapeutic horizons in rheumatoid arthritis: an In-depth exploration of circular RNAs derived from plasma exosomes by Guoqing Li, Hongyi Chen, Jiacheng Shen, Yimin Ding, Jingqiong Chen, Yongbin Zhang, Mingrui Tang, Nan Xu, Yuxuan Fang

“…Diagnostic performance evaluated via receiver operating characteristic (ROC) curves using pROC for area under the curve (AUC). Optimal LASSO model with 4 circRNAs determined, with AUC > 0.6 for key genes. …”
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Performance of Cementless Hip Arthroplasty Stem Types Based on Consolidated Large Registry Data by Logan E. Finger, MD, Matthew F. Gong, MD, Asher Mirvish, BS, Alexandra S. Gabrielli, MD, Ahmad P. Tafti, PhD, Michael J. O’Malley, MD, Brian A. Klatt, MD, Johannes F. Plate, MD, PhD

“…Background: Improvements in cementless total hip arthroplasty have been directed at optimizing osseointegration of the femoral implant to reduce aseptic loosening rates. …”
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Synergistic effects of Vachellia nilotica-derived zinc oxide nanoparticles and melatonin on drought tolerance in Fragaria × ananassa by Tauseef Anwar, Alia Safdar, Huma Qureshi, Ejaz Hussain Siddiqi, Naimat Ullah, Muhammad Tahir Naseem, Walid Soufan

“…These findings highlight the combined application of ZnO NPs and MT as a promising strategy to enhance growth and stress tolerance in strawberry plants, warranting further research on optimized concentrations, delivery methods, and molecular mechanisms.…”
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Study of the Shock Absorption Effectiveness of Air Cushions by Jacek Roguski, Leszek Jurecki, Ryszard Łyszczek, Krzysztof Cygańczuk

“…In order to ensure an optimal level of safety while minimising the risk of serious injuries to both rescuers and rescued people, it is important to understand the excessive deceleration mechanisms during a fall from a significant height. …”
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Electrochemical Sensors Based on Single-Wall Carbon Nanotubes in Voltammetric Ascorbic Acid Tests by Natalia V. Ivanova, Elizaveta A. Martynova, Anna I. Vershinina, Maksim V. Lomakin, Galina O. Eremeeva, Olesya R. Gordaya, Sergey D. Shandakov

“…The single-wall carbon nanotubes were collected on a nitrocellulose filter in the form of films with transmittances of 10% in the middle of the visible wavelength (550 nm). The method was optimized to involve air annealing at 300–320°C and a treatment with strong inorganic acids, i.e., HCl, HNO3 + H2 SO4 . …”
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Comprehensive Analysis of a Bridged-T Pre-Equalizer Circuit for High-Speed Visible Light Communications by Siti Hajar Ab Aziz, Norhanis Aida Mohd Nor, Suriza Ahmad Zabidi

“…This precise point ensures optimal matching to 50 ? of source and load impedance. …”
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A Critical Appraisal of System-Reported Organ Dose (OD) Versus Manually Calculated Mean Glandular Dose (MGD) in Dubai’s Mammography Services by Kaltham Abdulwahid Mohammad Noor, Norhashimah Mohd Norsuddin, Muhammad Khalis Abdul Karim, Iza Nurzawani Che Isa, Vaidehi Ulaganathan

“…These findings empower practitioners to optimize dose levels, ensuring safer and more effective breast cancer screening protocols.…”
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SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma ce... by Tianci Han, Xiaoqi Guo, Junwei Xie, Wei Tong, Liang Zhang

“…Conclusions Our data deciphered the mechanism of ETV1-mediated M2 macrophage infiltration in the TME of ESCC, which has important implications for the development of novel prognostic and therapeutic targets to optimize current therapies against ESCC.…”
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Short-Term Efficacy of Using a Novel Low-Volume Bone Marrow Aspiration Technique to Treat Knee Osteoarthritis: A Retrospective Cohort Study by Daniel Kuebler, Alexandra Schnee, Lisa Moore, Jason Kouri, Alexis McLaughlin, Robert Hanson, Patrick Kuebler, Ignacio Dallo, Alberto Gobbi

“…Given the various aspiration and concentration methods available for preparing bone marrow, more data are needed to identify the optimal bone marrow harvesting techniques to treat OA. …”
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Effects of exercise dose based on the ACSM recommendations on depression in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials by Yang Fang, Yang Fang, Bai Xiaoling, Li Huan, Li Huan, Guan Yaping, Zhang Binying, Wang Man, Wu Juan, Liu Xinyu

“…ObjectiveTo explore the impact of various exercise doses on depressive symptoms among hemodialysis patients and offer valuable guidance for the selection of optimal exercise doses in clinical practice settings.MethodsA comprehensive systematic review was conducted across four major databases, namely, PubMed, Embase, Web of Science, and Cochrane Library, covering the period from their inception until August 2024. …”
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Spatiotemporal Variation and Driving Factors of Carbon Sequestration Rate in Terrestrial Ecosystems of Ningxia, China by Yi Zhang, Chunxiao Cheng, Zhihui Wang, Hongxin Hai, Lulu Miao

“…Based on ground observation data and multimodal datasets, the optimal machine learning model (EXT) was used to invert a 30 m high-resolution vegetation and soil carbon density dataset for Ningxia from 2000 to 2023. …”
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