FEATURES OF THE MODEL OF A SPECIALIZED GEOSPATIAL DATABASE FOR VISUALIZING INDICATORS OF HUMAN SOCIO-ECONOMIC SECURITY IN WARTIME CONDITIONS by Zakharii S. Varnalii, Oleksii P. Fedchenko, Ihor V. Pampukha, Ihor V. Tolok

“…They enable the analysis of situations, the prediction of event developments, and the formulation of optimal action strategies. Modern geographic information systems, particularly ArcGIS, offer a full range of tools for collecting, organizing, and analyzing geographic data that characterize socio-economic aspects of development at local and global levels. …”
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Clinical Outcome Discrimination in Pediatric ARDS by Chest Radiograph Severity Scoring by Yu-Chun Yan, Wen-Han Hao, Feng-Sen Bai, Shuang Liu, Dong Qu, Xin-Yu Yuan

“…The ROC curve and survival curve were established, and the optimal cutoff score for discrimination prognosis was set. …”
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Evaluation of mucosal adjuvants to chitosan-nanoparticle-based oral subunit vaccine for controlling salmonellosis in broilers by Raksha Suresh, Shekoni Olaitan Comfort, Sara Dolatyabi, Jennifer Schrock, Mithilesh Singh, Gourapura J. Renukaradhya

“…Our data reaffirmed the potent adjuvanticity of both of these adjuvants and identified their optimal dose when entrapped in mChitosan-NP to potentiate the immunogenicity and efficacy of orally delivered mChitosan (OMP+FLA)/FLA-NP vaccine. …”
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Effect on Physical and Mechanical Properties of Conventional Glass Ionomer Luting Cements by Incorporation of All-Ceramic Additives: An In Vitro Study by Runki Saran, Nagraj P. Upadhya, Kishore Ginjupalli, Arul Amalan, Bharath Rao, Saurabh Kumar

“…Conclusion. 10% concentration of the two all-ceramic powders can be regarded as the optimal concentration for enhancing the glass ionomer luting cements’ strength. …”
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Development and Evaluation of selective nitroxanthone Derivatives: A promising compound for Targeting MCF-7 breast cancer cells by Pavithren Devakrishnan, Nadiah Mad Nasir, Johnson Stanslas, Muhammad Alif M. Latif, Ahmad Zaidi Ismail, Fatin Farhana Baharuddin

“…Molecular docking analysis showed that compound 1 binds more efficiently to the target enzyme aromatase compared to other derivatives, likely due to its optimal number of nitro groups, orientations, and polarizabilities. …”
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Strategies for enhancing home-based cardiac rehabilitation self-management for patients with coronary heart disease: a qualitative study by Zhen Yang, Xutong Zheng, Yu Gao, Chunqi Zhang, Aiping Wang

“…This provides theoretical support for optimizing intervention measures and promotes the effective delivery and application of self-management strategies in practice. …”
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Comparative analysis of volume growth processes of Masson pine and Chinese fir forests in different regions of southern China by YuHui Chen, Zongzheng Chai

“…Tailored management practices that align with local climatic and environmental conditions are recommended to optimize growth and ensure sustainable management and development of P. massoniana and C. lanceolata forests.…”
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Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT) by Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa

“…PDT involves the administration of photoactive substances called photosensitizers (PS) that selectively accumulate in cancer cells and are subsequently excited/activated by irradiation with light at wavelengths of optimal absorbance. Activated PS leads to the generation of singlet oxygen and other reactive oxygen species (ROS), promoting cancer cell death. 5-aminolevulinic acid (5-ALA) is a naturally occurring PS precursor, which is metabolically converted to the PS, protoporphyrin IX (PPIX). …”
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Dosage of joint mobilisation for the management of rotator cuff-related shoulder pain: protocol for a scoping review by Steve Tumilty, Daniel C Ribeiro, Sizhong Wang, Cathy M Chapple, Dusty Quinn

“…Mapping and summarising the reported type and dosage of joint mobilisations for patients with rotator cuff-related shoulder pain from previous studies will provide a foundation for further optimal selection of type and dosage of joint mobilisations for treating patients with rotator cuff-related shoulder pain. …”
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Unlocking faba bean (Vicia faba L.) potential: How cattle manure and fertilizer boost yields in Kaffa Zone, South-Western Ethiopia by Isreal Zewide, Asrat Ademe

“…This study aimed to optimize faba bean (Vicia faba L.) productivity in Adiyo, southwest Ethiopia, by evaluating the influence of cattle manure (CAM) and blended nitrogen phosphrous sulfur and boron (NPSB) fertilizer rates during the 2023 crop season. …”
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Second-line systemic treatment for metastatic colorectal cancer: A systematic review and Bayesian network meta-analysis based on RCT. by Chengyu Sun, Enguo Fan, Luqiao Huang, Zhengguo Zhang

“…<h4>Background</h4>The optimal second-line systemic treatment for metastatic colorectal cancer (mCRC) is inconclusive.…”
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U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults by Chuanwei Zhao, Xiaochun Zhang, Xu Zhang, Bo Zhao, Yane Yang, Mu Lin, Wenli Qiao, Zeyao Hu, Haijie Yang

“…Further longitudinal studies are required to validate these findings and determine optimal lipid management strategies for osteoporosis prevention.…”
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Interfacial and mass transport phenomena in the tri-ethylene glycol-methane system at process conditions of natural gas dehydration by Stanley Ibeh, Philip Jaeger

“…Abstract Understanding the phase and interphase behavior at equilibrium and during the mass transfer between two adjacent fluid phases is relevant for optimizing and designing efficient separation processes. …”
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Carbon Budget Assessment and Influencing Factors for Forest Enterprises in the Key State-Owned Forest Area of the Greater Khingan Range, Northeast China by Hui Wang, Wenshu Lin, Jinzhuo Wu, Zhaoping Luan

“…Influencing factors are identified through correlation analysis and the optimal parameter geographical detector (OPGD), while their spatial-temporal variations and causal relationships are analyzed using the geographical and temporal weighted regression model (GTWR) and structural equation modeling (SEM). …”
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A Rapid and Nondestructive Quality Detection Approach for Yongchuan Xiuya Tea Based on NIRS and siPLS-ANN Method by Ying Zhang, Jie Wang, Xiuhong Wu, Rui Chang, Hongyu Luo, Juan Yang, Quan Wu, Ze Xu, Yingfu Zhong

“…Through preprocessing the spectral data and employing the synergy interval partial least squares (siPLS) method to identify characteristic spectral regions, principal component analysis (PCA) is applied, followed by the development of a Jordan–Elman artificial neural network prediction model (ANN) for tea quality assessment. The optimal spectral preprocessing approach identified in this study is a combination of multiplicative scatter correction and second derivative processing. …”
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Factors influencing breast milk donation to a human milk bank in Iran: implications for policymakers and planners by Leila Doshmangir, Maryam Naghshi, Kamal Gholipour, Ayat Ahmadi, Hosein Azizi, Vladimir Sergeevich Gordeev

“…Abstract Background The World Health Organization (WHO) actively promotes breastfeeding as the optimal source of nourishment for infants and young children. …”
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Use of Multiple Doses of Intravenous Infusion of Umbilical Cord-Mesenchymal Stem Cells for the Treatment of Adult Patients with Severe COVID-19-Related Acute Respiratory Distress S... by Po-Ren Hsueh, Sung-Jung Ho, Po-Chuen Hsieh, I-Min Liu, Shio-Shin Jean

“…In Taiwan, few adult patients with severe COVID-19-induced ARDS receiving compassionate adjuvant treatment consisting of either a single dose (1–10 × 106 cells/kg body weight (kg BW)) or three doses (5 × 106 cells/kg BW in each dose) of IVF-UC-MSCs had good outcomes. However, the optimal dosage and rounds of IVF-UC-MSCs administration for the treatment of severe COVID-19 patients with ARDS are undetermined. …”
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Deep-TEMNet: A Hybrid U-Net–2D LSTM Network for Efficient and Accurate 2.5D Transient Electromagnetic Forward Modeling by Zhijie Qu, Yuan Gao, Kang Xing, Xiaojuan Zhang

“…The U-Net component enables high-resolution spatial feature extraction, while the 2D LSTM module enhances temporal modeling by processing spatial sequences in two dimensions, thereby optimizing the representation of electromagnetic field dynamics over time. …”
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Effect of Biofloc Culture on the Daily Rhythmicity of the Activity and Expression of Digestive Enzymes in Tilapia, Oreochromis niloticus by María del Carmen Monroy-Dosta, Daniel Becerril-Cortés, Juan Pablo Lazo, Arturo Mena-López, Pilar Negrete-Redondo, Eliasid Nogueda-Torres, Carmen Navarro-Guillén, José Antonio Mata-Sotres

“…These findings should be considered when establishing new optimized culture protocols.…”
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The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development by Pralay Mukhopadhyay, Hesham A. Abdullah, Joanna B. Opalinska, Prani Paka, Eric Richards, Katja Weisel, Suzanne Trudel, Maria-Victoria Mateos, Meletios Athanasios Dimopoulos, Sagar Lonial

“…Protocol amendments reflecting DREAMM-3 learnings could also be implemented prospectively on the combinations trials to optimize the follow-up duration and mitigate risk. …”
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