Antithrombotic Therapy Duration after Patent Foramen Ovale Closure for Stroke Prevention: Impact on Long-Term Outcome by Joelle Kefer, Karlien Carbonez, Sophie Pierard, François-Pierre Mouthuy, Andre Peeters, Cedric Hermans, Catherine Lambert, Christophe DeMeester, Thierry Sluysmans, Agnes Pasquet

“…Background. The optimal duration of antithrombotic therapy (ATT) after patent foramen ovale (PFO) closure remains under debate. …”
Get full text

Effects of Light Spectra on Nutritional Composition in Juvenile Sinonovacula constricta (Lamarck 1818) and Transcriptomic Analysis by Mengqi Zhang, Fei Kong, Deshui Chen, Xiaojun Yan, Zhaoshou Ran, Jilin Xu

“…Overall, our study recommends cultivating juvenile S. constricta under yellow light to optimize their growth and nutritional value. Further research could delve deeper into the molecular mechanisms underlying the effects of different light spectra on S. constricta to enhance our understanding of how light influences aquaculture practices and the nutritional quality of seafood products.…”
Get full text

The impact of sleep interventions combined with enhanced nutritional support on sleep quality, nutritional status, pain management, psychological well-being, and quality of life in... by Gang Wang, Shengjie Pan

“…These findings underscore the value of integrating multifaceted interventions into standard postoperative care to optimize recovery trajectories and overall well-being.…”
Get full text

Fuzzy Logic Recommender Model for Housing by Emanuel G. Munoz, Jaime Meza, Sebastian Ventura

“…Euclidean distance is employed in order to measure the similarity between user preferences and housing characteristics, after which the search time is optimized by utilizing metaheuristic methods, of which the bat algorithm provides the best performance in terms of time. …”
Get full text

Stem Cell–Based Therapies via Different Administration Route for Stroke: A Meta-analysis of Comparative Studies by Gabriella Jeanne Mulia, Novelia Anna, John Chung-Che Wu, Hon-Ping Ma, Yung-Hsiao Chiang, Ju-Chi Ou, Kai-Yun Chen

“…Further research is required to standardize treatment protocols, optimize cell types and doses, and address patient-specific factors to integrate stem cell therapies into routine clinical practice.…”
Get full text

Three-Dimensional Inversion of Borehole-Surface Resistivity Method Based on the Unstructured Finite Element by Zhi Wang, Sinan Fang

“…The quasi-Newton method with limited memory (L_BFGS) is used to optimize the objective function in the inversion calculation, and a double-loop recursive method is used to solve the normal equation obtained at each iteration in order to avoid computing and storing the sensitivity matrix explicitly and reduce the amount of calculation. …”
Get full text

The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes by Christoph Beyersdorf, Max Prost, Melanie Elisabeth Röckner, Uwe Martin Maus, Cornelius Jacobs, Max Joseph Scheyerer

“…Thus, prioritizing interventions aimed at preventing progressive sintering and restoring sagittal balance is paramount in optimizing treatment outcomes for affected individuals.…”
Get full text

Hypoglycaemia due to insulin therapy for the management of hyperkalaemia in hospitalised adults: A scoping review. by Mogamat-Yazied Chothia, Toby Humphrey, Anel Schoonees, Usuf Mohamed Ebrahim Chikte, Mogamat Razeen Davids

“…Future randomised trials should focus on identifying the optimal regimen of insulin therapy to mitigate the risk of hypoglycaemia.…”
Get full text

Design and Test of a Cone Dielectric Elastomer Actuator Driving Hopping Robot by Yunguang Luan, Huaming Wang, Ling Zhou, Haichao Song

“…However, they are often limited by their low output power, which can make their integration into dynamic systems like hopping robots particularly challenging. This research optimizes the performance by introducing a cone DEA with a novel type of semi-diamond preload mechanism. …”
Get full text

Optimasi Jaringan 4G LTE pada Jalur Tol Cikopo Palimanan dengan Menggunakan Metode Physical Tuning by Hajiar Yuliana, Muhammad Reza Hidayat, Ade Sena Permana, Nivika Tiffany Somantri, Ni Ketut Hariyawati Dharmi

“…Namun, teknologi 4G ini memiliki beberapa kendala yang menyebabkan kecepatan jaringan menjadi optimasi jaringan untuk memperbaiki kualitas jaringan agar dapat dipakai dengan optimal. Pada penelitian ini dilakukan proses optimasi untuk memperbaiki kondisi level sinyal Reference Signals Received Power (RSRP) di Jalur Tol Cikopo-Palimanan (Cipali). …”
Get full text

Enhancing patient education on the role of tibial osteotomy in the management of knee osteoarthritis using a customized ChatGPT: a readability and quality assessment by Stephen Fahy, Stephan Oehme, Danko Dan Milinkovic, Benjamin Bartek

“…Two ChatGPT-4 models were compared: a native version and a fine-tuned model (“The Knee Guide”) optimized for readability and source citation through Instruction-Based Fine-Tuning (IBFT) and Reinforcement Learning from Human Feedback (RLHF). …”
Get full text

Multispecies fisheries management of the Sultanate of Oman using bioeconomic model by Sachinandan Dutta, Majid Al Harthy, Saud M. Al Jufaili, Ibtisam Al Abri

“…Rastrelliger kanagurta exhibited the highest growth rate (r = 0.260), with similar catchability coefficients (q) between R. kanagurta (2.18E-05) and S. commerson (2.93E-05), and T. albacares (8.48E-06) and S. longiceps (8.41E-06). Optimal fishing effort was calculated using the catch per unit effort (CPUE) hypothesis. …”
Get full text

Three-Dimensional Printable Magnetic Hydrogels with Adjustable Stiffness and Adhesion for Magnetic Actuation and Magnetic Hyperthermia Applications by Xueting Xuan, Yi Li, Xing Xu, Zhouyi Pan, Yu Li, Yonghao Luo, Li Sun

“…Furthermore, the integration of Fe₃O₄ nanoparticles and nanoclay into the AM precursor optimizes the rheological properties and ensures high printability, enabling the fabrication of complex, high-fidelity structures through extrusion-based 3D printing. …”
Get full text

Study on the Analgesic Efficacy of Femoral Nerve Block for Post-Hip Arthroscopy Pain by Mengwen Xue, Li Zhang, Ruiping Bai, Rui An, Jiarui Li, Xin Shen

“…Therefore, we designed this study to investigate the analgesic efficacy and optimal drug concentrations of FNB after hip arthroscopy. …”
Get full text

The regular effects of concurrent aerobic and resistance exercise on global cognition in healthy elderly populations: A systematic review with meta-analysis of randomized trials by Liang Ding, Lijie Lou, Mingyang Zhang, Xing Zhang

“…Future research should investigate optimal training combinations and sequences to maximize cognitive benefits.…”
Get full text

Boundary layer flow of a non-Newtonian fluid over an exponentially stretching sheet with the presence of a heat source/sink by Vinod Y．, K.R. Raghunatha, Suma Nagendrappa Nagappanavar, Nodira Nazarova, Manish Gupta, Sangamesh

“…It bridges the gap between theoretical fluid dynamics and practical heat transfer applications, providing insights for optimizing systems involving Casson fluids under thermal effects.…”
Get full text

Potentiation of Doxorubicin Cytotoxicity Utilizing Clarithromycin Loaded-PEGylated Liposomes by Islam Alfreahat MS, Hamdi Nsairat PhD, Ibrahim Deeb Aldeeb PhD, Ali Al-Samydai PhD, Walhan Alshaer PhD

“…Results The CAM/DOX-PEGylated liposomes exhibited optimal average particle size (238 ± 26.7 nm), PDI (0.29 ± 0.107), and zeta potential (−20.9 ± 2.17 mV). …”
Get full text

Prevention and Control of Losses of Gaseous Nitrogen Compounds in Livestock Operations: A Review by A.A. Jongebreur, G.J. Monteny

“…As N2O is an intermediate product of complex biochemical processes of nitrification and denitrification, optimal conditions are the key issues in N2O reduction strategies. …”
Get full text

New Technology of Functional Bakery Products by Olga L. Ladnova, Svetlana Ya. Koryachkina, Vladimir P. Koryachkin, Larisa S. Bolshakova

“…The high-protein raw materials increased the protein content in bread by 41.9–46.4%, compared to the control sample, which equaled 33.1–34.2% of the recommended daily intake per 100 g of bread. The optimal ratio of wholemeal high-protein pea flour and wheat gluten was 20/80 for the San Cipriano samples and 30/70 for the Vega variety.…”
Get full text

Liposomal Formulations: A Recent Update by Surendra S. Agrawal, Vrinda Baliga, Vaishali Y. Londhe

“…Drug encapsulation can be optimized by creating lipid compositions that match a drug’s charge and hydrophobicity. …”
Get full text