Voxel-Wise Brain-Wide Functional Connectivity Abnormalities in Patients with Primary Blepharospasm at Rest by Pan Pan, Shubao Wei, Huabing Li, Yangpan Ou, Feng Liu, Wenyan Jiang, Wenmei Li, Yiwu Lei, Yanqing Tang, Wenbin Guo, Shuguang Luo

“…SVM analysis showed that increased GFC values in the right postcentral gyrus/precentral gyrus/paracentral lobule could discriminate patients from controls with optimal accuracy, specificity, and sensitivity of 83.33%, 83.33%, and 83.33%, respectively. …”
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Evaluation of Chest CT Scan as a Screening and Diagnostic Tool in Trauma Patients with Coronavirus Disease 2019 (COVID-19): A Cross-Sectional Study by Hossein Abdolrahimzadeh Fard, Salahaddin Mahmudi-Azer, Sepideh Sefidbakht, Pooya Iranpour, Shahram Bolandparvaz, Hamid Reza Abbasi, Shahram Paydar, Golnar Sabetian, Mohamad Mahdi Mahmoudi, Masoume Zare, Leila Shayan, Maryam Salimi

“…The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. …”
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Electric field-assisted embedding of fiber optic sensors in structural materials for structural health monitoring by Xinchang Zhang, Joshua Daw, Charles Payne, Bibo Zhong, Austin Fleming, Zilong Hua, Jorgen Rufner

“…Samples fabricated under optimal conditions passed helium leak testing, confirming effective interfacial bonding. …”
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Cold-induced metabolic adaptations in the large yellow croaker Larimichthys crocea by Yang Gao, Huirong Lv, Chengzhang Huang, Xiaoyu Qu, Zhangjie Chu, Weiye Li, Xiaolong Yin, Jungyeol Park, Dejun Feng, Junwook Hur

“…Omics data revealed that the ABC transporter, glycolysis and oxidative phosphorylation pathways were downregulated, whereas the citrate cycle pathway was upregulated, suggesting a metabolic adjustment to optimize ATP production and cellular transport mechanisms for efficient energy utilization and metabolic homeostasis. …”
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Spatiotemporal variation and influencing factors of phosphorus in Asia’s longest river based on receptor model and machine learning by Gege Cai, Jiamei Zhang, Wanlu Li, Jiejun Zhang, Yun Liu, Shanshan Xi, Guolian Li, Haibin Li, Xing Chen, Fanhao Song, Fazhi Xie

“…This study provides useful information for optimizing phosphorus pollution management and strategies for eutrophication control in the Yangtze River as well as in other large watersheds.…”
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Application of metagenomic next-generation sequencing (mNGS) to describe the microbial characteristics of diabetic foot ulcers at a tertiary medical center in South China by Hongteng Xie, Zhaohong Chen, Guohua Wu, Pei Wei, Teng Gong, Shun Chen, Zhaorong Xu

“…Conclusion The mNGS method had a higher positive detection rate and identified a broader spectrum of microorganisms in DFUs, thus, mNGS provided a more comprehensive understanding of the microbiome of DFUs to facilitate the development of timely and optimal treatment. Trial registration The study was conducted in accordance with the Declaration of Helsinki and approved by the Ethical Review Committee of the Fujian Medical University Union Hospital (approval number 2021KY054).…”
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A thermo-responsive chitosan-based injectable hydrogel for delivery of curcumin-loaded polycaprolactone microspheres to articular cartilage: in-vitro and in-vivo assessments by Farnoosh Kalantarnia, Sasan Maleki, Amir Shamloo, Kazem Akbarnataj, Sayed Navid Tavoosi

“…While injectable hydrogels have shown potential as a treatment, achieving an optimal balance between bio-compatibility, mechanical properties, and drug delivery remains a challenge. …”
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A Method and Engineering Practice for a Fully Mechanized Caving Coalface to Rapidly Pass Through a Large Fault by Wei Zhang, Feili Yang, Jingyu Chang, Shengxun Zhao, Bin Xu, Jinyong Xiang

“…Based on the occurrence characteristics of the F₆ fault (maximum throw: 13.5 m) in the #3_up1101 fully mechanized caving coalface at Gaozhuang Coal Mine, two different solutions allowing the coalface to pass through this fault were proposed, and the solution of pre-driven roadways with rock pillars was optimally determined. The main implementation steps of the method include designing the layout parameters of the pre-driven roadways, determining the width for rock pillars between the adjacent pre-driven roadways, construction of pre-driven roadways by smooth wall blasting, and controlling the surrounding rock deformation of the pre-driven roadways. …”
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Rapid and simple detection of Candida albicans using closed dumbbell-mediated isothermal amplification by Yanli Zhang, Xuhan Chen, Yeling Zhong, Fei Guo, Guifang Ouyang, Rui Mao

“…All primers were selected and evaluated by real-time fluorescence monitoring and endpoint visual judgement indicated by hydroxy naphthol blue (HNB). Optimal primers and accelerate primers (out primers and loop primers) were designed and selected after confirmation of the fundamental CDA primers to achieve more efficient CDA reaction for C. albicans detection (CA-OL-CDA).ResultsAfter establishment of the assay, 9 non-Candida albicans strains, including 3 Candida species were tested to negative by adopting the established CA-OL-CDA assay, indicated high specificity. …”
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Development and design validation of a novel network meta-analysis presentation tool for multiple outcomes: a qualitative descriptive study by Lehana Thabane, Jason W Busse, Behnam Sadeghirad, Gordon H Guyatt, Mohit Bhandari, Romina Brignardello-Petersen, Fernando Kenji Nampo, Carlos A Cuello-Garcia, Raveendhara R Bannuru, Mark R Phillips, Yu Jia Guo, Sofia Bzovsky

“…Objective The Grades of Recommendations, Assessment, Development and Evaluation working group recently developed an innovative approach to interpreting results from network meta-analyses (NMA) through minimally and partially contextualised methods; however, the optimal method for presenting results for multiple outcomes using this approach remains uncertain. …”
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Factors Determining the Removal Efficiency of Procion MX in Waters Using Titanate Nanotubes Catalyzed by UV Irradiation by Vo Nguyen Xuan Que, Tran Tien Khoi, Nguyen Thi Thuy, Ta Thi Minh Dung, Dao Thi Thanh Binh, Nguyen Nhat Huy

“…Particularly, the PMX degradation using titanate nanotubes was optimized under the UV-A intensity of 100 W/m2. The dye was degraded by more than 95% at the TNTs concentration of 75 mg/L and pH 8.0 after 90 min. …”
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Combining a Standardized Growth Class Assessment, UAV Sensor Data, GIS Processing, and Machine Learning Classification to Derive a Correlation with the Vigour and Canopy Volume of... by Ronald P. Dillner, Maria A. Wimmer, Matthias Porten, Thomas Udelhoven, Rebecca Retzlaff

“…Model overall performance metrics were optimized with grid search-based hyperparameter tuning and repeated-k-fold-cross-validation. …”
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Correlation between carbapenem susceptibility in Pseudomonas aeruginosa and modified antibiotic heterogeneity index: a multicenter observational study using a surveillance platform by Keisuke Sawada, Takaaki Kato, Shuji Kono, Hiromi Kaneko, Hayato Nakano, Shinobu Inada, Tatsuya Isogawa, Tadahiro Shimizu, Namiko Takahashi, Haruki Takano, Hiroaki Chiba, Makoto Sugimoto, Ryo Inose, Yuichi Muraki, Hideki Araoka

“…However, a significant correlation was observed between carbapenem susceptibility and the mAHI (r = 0.261, P = .02), which also demonstrated a higher predictive accuracy for high susceptibility rates than that of the AHI (area under the curve: 0.75 vs 0.58, p < .01). The optimal mAHI cutoff value for predicting 90% susceptibility was 0.765, with a sensitivity of 67.7% and specificity of 76.5%. …”
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Estimation of Abbreviated Cyclosporine A Area under the Concentration-Time Curve in Allogenic Stem Cell Transplantation after Oral Administration by Hanene ELjebari, Nadia Ben Fradj, Issam Salouage, Emna Gaies, Sameh Trabelsi, Nadia Jebabli, Mohamed Lakhal, Tarek Ben Othman, Anis Kouz

“…The LSS equation with the best predictive performance (bias, precision and number of samples) utilized three sampling concentrations was AUC0–12 h=0.607+1.569×𝐶0.5+2.098×𝐶2+3.603×𝐶4(R2=0.943). Optimal LSSs equations which limited to those utilizing three timed concentrations taken within 4 hours post-dose developed from ASCT recipient's patients yielded a low bias <5% ranged from 1.27% to 2.68% and good precision <15% ranged from 9.60% and 11.02%. …”
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Relapse detection in the Danish surveillance program of patients with clinical stage I seminoma: a nationwide study by Niklas B. Lindahl, Jakob Lauritsen, Thomas Wagner, Gedske Daugaard, Mikkel Bandak

“…Reduction of visits and omission of routine physical examinations can safely be considered for patients with a low risk of relapse, while further research is needed to optimize follow-up and treatment for patients at higher risk of relapse. …”
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Optic Nerve Sheath Diameter in Predicting the Neurological Outcomes of Cardiac Arrest Survivors: A Systematic Review and Meta-analysis by Parisa Jafari Khouzani, Erfan Rahmani, Mehdi Rezaei, Sasan Pohrbagher Benam, Atousa Moghadam Fard, Reza Amani-Beni, Maziar Daneshvar, Faezeh Jalayer Sarnaghy, Naghme Masoomi Goodarzi, Ramila Abedi Azar, Amirhossein Mirbolook, Peyman Bashghareh, Elham Bibak, Babak Goodarzi, Zahra Salarinezhad, Reza Zahedpasha, Marzieh Hajizaman, Negar Pourhossein Rahmani, Azam Darvishi, Alireza Hadizadeh, Fatemeh Zandi, Ashkan Azizi, Armin Naderi, Sepideh Shah Hosseini, Asie Sanjary, Mozhdeh Mohammadi Virsoudi, Habibollah Afshang, Seyedsaber Mirabdali, Navid Fathalian, Pouria Momeni, Mahsan Valizade, Fateme Nozari, Hamed Ghorbani, Sanam Mohammadzadeh, Seyed Kiavash Sajadi, Azam Abdollahi, Mehrdad Farrokhi

“…However, since the cut-off values and methods of ONSD measurement affect its predictive performance, further studies will be required to standardize these factors to achieve optimal predictive parameters. …”
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Cardiac CT reveals high prevalence of coronary artery disease in esophageal cancer eligible for radiotherapy by Akinori Takada, Satoshi Nakamura, Yutaka Toyomasu, Takamitsu Mase, Tomoko Kawamura, Suguru Araki, Yoshitaka Suzuki, Masaki Ohi, Hajime Sakuma, Yoshihito Nomoto, Kakuya Kitagawa

“…Incorporating cardiac CT findings into radiotherapy planning is recommended to optimize patient care. …”
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Estimating and forecasting bitcoin daily prices using ARIMA-GARCH models by Quang Phung Duy, Oanh Nguyen Thi, Phuong Hao Le Thi, Hai Duong Pham Hoang, Khanh Linh Luong, Kim Ngan Nguyen Thi

“…Findings – Using the Box–Jenkins method, various AR and MA lags were tested to determine the most optimal lags. ARIMA (12,1,12) is the most appropriate model obtained from the various models using AIC. …”
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SumGPT: A Multimodal Framework for Radiology Report Summarization to Improve Clinical Performance by Tipu Sultan, Mohammad Abu Tareq Rony, Mohammad Shariful Islam, Samah Alshathri, Walid El-Shafai

“…In the future, this approach could pave the way for applications in other medical domains while further optimizing the model for real-time clinical use.…”
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Age- and Sex-Specific Risks of Major Cardiovascular Complications and All-Cause Mortality Following Elective Hip and Knee Arthroplasty in the Netherlands: A Dutch Hospital Data Reg... by Mark J.R. Smeets, MD, Maaike G.J. Gademan, PhD, Rob G.H.H. Nelissen, MD, PhD, Suzanne C. Cannegieter, MD, PhD, Banne Nemeth, MD, PhD

“…Yet, stratified up-to-date absolute risk estimates, which are needed to optimize prevention, are lacking. Methods: All Dutch patients who had a first primary THA and TKA for osteoarthritis between 2015 and 2021 were included. …”
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