Progress Analysis and Development Prospects of Soil Ecological and Environmental Effects of Interlayer Construction by JIA Zhenjiang, WU Yangyang, LI Wangcheng, MA Dongxiang, CHEN Jihong, GAO Susu, NIU Xiaoxiao, XU Tianyuan

“…This also includes developing and integrating cost-effective and practical interlayer laying technology and supporting equipment, as well as screening and optimizing key technologies and operational parameters for interlayer construction suitable for various climate conditions, soil textures, crop layouts, and farmland management methods. …”
Get full text

Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Eff... by Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

“…Inactivated multidrug-resistant RT (RT1.14opt-in) was N-terminally fused to the signal providing secretion of NS1 protein of TBEV (Ld) generating optimized inactivated Ld-carrying enzyme RT1.14oil. …”
Get full text

Neutrophil to Lymphocyte Ratio as a Predictor of Adverse Outcome in Patients with Decompensated Liver Cirrhosis by Valeriy D. Lunkov, Marina V. Maevskaya, Ekaterina K. Tsvetaeva, Ana G. Mendez, Maria S. Zharkova, Petr E. Tkachenko, Vladimir T. Ivashkin

“…Correlation analysis, univariate and multivariable analysis were provided to find factors statistically significantly associated with lethal outcome and SIRS. The optimal cut-off levels for the NLR associated with adverse outcome were determined.Results. …”
Get full text

Epigallocatechin-3-gallate inhibits the collagen accumulation of oral submucous fibrosis induced by arecoline by Ge Gao, Ge Gao, Caipeng Lin, Caipeng Lin, Ruibo Li, Xi Xie, Hai-Bin Luo, Hai-Bin Luo

“…However, the research on OSF regarding EGCG is relatively limited.PurposeWe aimed to investigate the potential therapeutic effect of EGCG against OSF using an arecoline (ARE) -induced rat model and primary rat oral fibroblasts.MethodsPrimary rat oral mucosal fibroblasts (ROMF) were isolated and identified. Optimal ARE concentrations were established using the Cell Counting Kit-8. …”
Get full text

Synchronization and Channel Estimation Design for Multi-Stream MIMO System in Sub-Terahertz Channel Model by Chung-Lun Tu, Chen-Yuan Tseng, Wei-Che Lee, Kang-Lun Chiu, Pei-Yun Tsai, Shyh-Jye Jou

“…At the architectural level, a shared optimized Golay correlator reduces hardware usage by 23%, efficiently handling multiple correlation lengths in a single design. …”
Get full text

Effect of continuous theta burst stimulation on the glymphatic system, brain network and cognitive function in patients with cerebral small vessel disease by Pei Dai, Hui-xian Yu, Zhao-xia Wang, Si-hao Liu, Chang-bin Liu, Guang-qing Xu

“…The Digital Span Test-backward (DST-backward) scores were significantly higher in the cTBS group than those in the control.ConclusionApplying cTBS to the DLPFC in CSVD may enhance the efficiency of brain glymphatic clearance, optimize network connectivity and improve cognitive function to a certain extent.…”
Get full text

Microstructure Evolution and Mechanical Properties of B₄C-Reinforced TC11 + xFe Composites Fabricated by HIP by Shenwei Qian, Nan Wang, Feng Chen, Yangyang Sun, Jiong Zhao, Hui Chang, Liang Feng, Lian Zhou

“…However, the addition of 2 wt% Fe at the same B₄C level (2 wt% B₄C + 2 wt% Fe-reinforced composites) resulted in a significant increase in hardness by 37.5% and 15.2% in compressive strengths of TMC and can be attributed to the solid solution strengthening effect and higher dislocation density provided by the addition of Fe. In addition, the optimal overall properties can be achieved by strictly regulating the addition ratio of 2 wt% Fe and 1 wt% B₄C, allowing for a compressive strength of 2301 MPa while still maintaining a compressive strain of 24.6%.…”
Get full text

Organizational factors impacting the implementation of a digital mental health tool in Alberta's mental health care of youth and young adults by Marianne Barker, Julia Hews-Girard, Karina Pinston, Sarah Daniel, Lauren Volcko, Lia Norman, Emilie Bassi, Katherine Bright, Ian Hickie, Frank Iorfino, Haley LaMonica, Karen Moskovic, Melanie Fersovitch, Jessica Bradley, Leanne Stamp, Jason Gondziola, David Johnson, Gina Dimitropoulos

“…Facilitators included positive attitudes towards using dMH to optimize clinical practices by empowering youth and improving continuity of care, transitions in care, and quality of care, as well as workplace culture and leadership. …”
Get full text

Comparison of the Effects of Sugammadex Recommended Dose (2 mg/kg) and Fixed Dose of 200 mg on the Reversal of Moderate Neuromuscular Block and Recovery Profile in Adult Patients by Ji-Yoon Jung, Sung-Ae Cho, Woojin Kwon, Hongwook Kim, Tae-Yun Sung

“…<i>Background and Objectives</i>: Neuromuscular blocking agents are essential to ensure optimal surgical conditions during general anesthesia. …”
Get full text

Enhancing immunotherapy efficacy with synergistic low-dose radiation in metastatic melanoma: current insights and prospects by Zahid Rafiq, Mingyo Kang, Hampartsoum B. Barsoumian, Gohar S. Manzar, Yun Hu, Carola Leuschner, Ailing Huang, Fatemeh Masrorpour, Weiqin Lu, Nahum Puebla-Osorio, James W. Welsh

“…Furthermore, we explore the challenges associated with LDRT’s integration into combination therapies, addressing crucial factors such as optimal dosage, fractionation, treatment frequency, and synergy with other pharmacological agents. …”
Get full text

Impact of Bone Marrow Aspirate Tregs on the Response Rate of Younger Newly Diagnosed Acute Myeloid Leukemia Patients by Mario Delia, Paola Carluccio, Anna Mestice, Claudia Brunetti, Francesco Albano, Giorgina Specchia

“…We studied 23 AML young patients, all treated with standard induction chemotherapy: OR (complete remission (CR) + CR incomplete (CRi)) was documented in 10 of 23 patients (44%); there were two partial responder patients. The optimal dBMA Treg cut-off value for predicting response to treatment (≥21/μL) was obtained by ROC curve analysis. …”
Get full text

Project “BUSSARD” − a holistic development of high-efficiency solar cells covering innovative front-end, metallization and interconnection approaches by Lorenz Andreas, Schube Jörg, Nikitina Veronika, Mack Sebastian, Schweigert Sebastian, Buddgard Jonas, Albrecht Jonas, Pospischil Maximilian, Kraft Achim, Wolf Andreas, Hermle Martin, Clement Florian

“…In this study we focus on multi-nozzle parallel dispensing, a technology that was developed as an alternative to standard screen-printing metallization and is used for the metallization of TOPCon solar cells for the first time. By optimizing the fabrication process at Fraunhofer ISE, we realize TOPCon solar cells (156.75 mm × 156.75 mm) with a champion conversion efficiency of up to ηmax = 24.2% (independently confirmed by Fraunhofer ISE CalLab PVCells). …”
Get full text

Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis by Gabriel Romero Liguori, Qihui Zhou, Tácia Tavares Aquinas Liguori, Guilherme Garcia Barros, Philipp Till Kühn, Luiz Felipe Pinho Moreira, Patrick van Rijn, Martin C. Harmsen

“…Progenitor cells cultured on biomaterials with optimal physical-topographical properties respond with alignment and differentiation. …”
Get full text

A fishy gut feeling – current knowledge on gut microbiota in teleosts by Ingvill Tolas, Ingvill Tolas, Zhigang Zhou, Zhen Zhang, Zhen Zhang, Tsegay Teame, Tsegay Teame, Rolf Erik Olsen, Einar Ringø, Ivar Rønnestad

“…Despite recent advances, further research is needed to elucidate species-specific mechanisms underlying GM-host interactions, the ecological implications of GM diversity, and its applications in aquaculture to optimize fish health and performance.…”
Get full text

Estimating population attributable risk fraction of determinants of pediatric obesity by Maryam Yazdi, Ibrahim Abdollahpour, Mostafa Qorbani, Saba Karimi, Mohammad Esmail Motlagh, Majid Khademian, Roya Kelishadi

“…These findings may provide insights for planning and optimizing future obesity intervention endeavors.…”
Get full text

Non-Destructive Early Detection of Drosophila Suzukii Infestation in Sweet Cherries (c.v. <i>Sweet Heart</i>) Based on Innovative Management of Spectrophotometric Multilinear Corre... by Giuseppe Altieri, Mahdi Rashvand Avaei, Attilio Matera, Francesco Genovese, Vincenzo Verrastro, Naouel Admane, Orkhan Mammadov, Sabina Laveglia, Giovanni Carlo Di Renzo

“…The external cross-validation set was initially set to 20% of the overall available samples and subsequently increased to 50% in the final selected optimal model. The identified procedure of management of regression algorithms allowed the selection of a very performant and robust model using the partial least squares regression algorithm: its false negative rate and false positive rate, after 500 Monte Carlo runs, were 0.004% +/− 0.003 and 0.02% +/− 0.01, respectively, and, in addition, the 50% of samples were used for the external cross-validation set.…”
Get full text

Insulator–metal transition in VO2 film on sapphire studied by broadband dielectric spectroscopy by Arsenii A. Gavdush, Vladislav A. Zhelnov, Kirill B. Dolganov, Alexander A. Bogutskii, Sergey V. Garnov, Maria G. Burdanova, Dmitry S. Ponomarev, Qiwu Shi, Kirill I. Zaytsev, Gennadii A. Komandin

“…Finally, we estimate somewhat optimal thickness and temperature of the $$\hbox {VO}_2$$ film in metallic phase for the THz optoelectronic applications. …”
Get full text

Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing by Youliang Shen, Yuelei Wang, Yidan Xu, Jie Wang, Chuqiang Yin, Zengshuai Han, Feng Shen, Ting Wang

“…Hes1 overexpression and animal models were constructed to study its role in UCMSCs differentiation and rotator cuff injury repair. CTGF was the optimal factor for inducing the differentiation of UCMSCs into tendon cells. …”
Get full text

Adenoviral Vector-Based Vaccine Expressing Hemagglutinin Stem Region with Autophagy-Inducing Peptide Confers Cross-Protection Against Group 1 and 2 Influenza A Viruses by Wen-Chien Wang, Ekramy E. Sayedahmed, Marwa Alhashimi, Ahmed Elkashif, Vivek Gairola, Muralimanohara S. T. Murala, Suryaprakash Sambhara, Suresh K. Mittal

“…The goal was to identify the optimal combination for enhanced immune responses and cross-protection. …”
Get full text

Myo-inositol increases respiratory burst, cellular proliferation, and phagocytosis of cultured leukocytes from Nile tilapia by Edgar Junio Damasceno Rodrigues, Pedro Luiz Pucci Figueiredo de Carvalho, Vitor Fernandes Silva, Delbert M. Gatlin, III, Margarida Maria Barros

“…Based on the results of all measured responses, 900 mg l-1 of MI was considered the optimal supplementation level for stimulating immunological functions of cultured Nile tilapia leukocytes. …”
Get full text