A Retrospective Claims-Based Study Evaluating Clinical and Economic Burden Among Patients With Moderate to Severe Osteoarthritis Pain in the United States by Patricia B. Schepman, Sheena Thakkar, Rebecca L. Robinson, Craig G. Beck, Deepa Malhotra, Birol Emir, Ryan N. Hansen

“…Assessing such longitudinal changes may be useful to patients and healthcare providers for tracking disease progression, informing treatment options, and employing strategies to optimize patient outcomes. **Objectives:** To characterize treatment patterns, HCRU, and costs over time in patients with moderate to severe (MTS) OA pain in the United States. …”
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Racial/ethnic differences in mental health treatment received among people with comorbid cardiometabolic and depressive symptomology: National Health and Nutrition Examination Surv... by Tyra Dark, Rachel Harris, Desiree Burns, Jacob Chernicky, Laura Reid-Marks, George Rust

“…Therefore, to achieve favorable health outcomes, policy should be implemented to optimize clinical treatment by addressing aspects of both conditions in an integrated approach and may need to be culturally tailored to be effective.…”
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Accelerating editorial processes in scientific journals: Leveraging AI for rapid manuscript review by Luca Fiorillo, Vini Mehta

“…AI automates routine tasks and accelerates decision-making processes, optimizing operations and data analysis. This paper discusses the emergence of AI chat assistants in various sectors, focusing on models like GPT-3, Watson Assistant, Dialogflow, Alexa, Siri, Cortana, and Google Bard. …”
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Effects of marble waste on shear strength and pullout resistance of sand reinforced with Glass Fiber-Reinforced Polymer (GFRP) bars by Shabir Hussain, Irshad Ahmad, Fasih Ahmed Khan, Waqas Ahmad, Beenish Jehan Khan

“…Therefore, GFRP bars embedded in optimized MWS mixtures are proposed as a sustainable and eco-friendly soil-reinforcement method, which is also helpful in reducing the depletion of natural resources and promoting a circular economy.…”
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USING DIGITAL BUSINESS SIMULATORS IN ECONOMIC AND MANAGERIAL DEVELOPMENT OF MASTER’S IN INFORMATION TECHNOLOGIES by Dmytro S. Antoniuk, Oleg M. Spirin, Tetiana A. Vakaliuk

“…The group showed learning progress toward conventional optimality in the simulated concepts. Used digital education resources provided acceptable ease of use and satisfying functionality of the analysis tools. …”
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Correlation between invasive and noninvasive oxygen indices in critically ill COVID patients with ARDS: A retrospective analysis by Arin Choudhury, Meena Singh, Amandeep Jaswal, Saurav Mitra Mustafi, Santvana Kohli

“…The area under the ROC curve of the S/F ratio was 0.720 (95% confidence interval [CI] 0.637–0.804) for mild ARDS. The optimal S/F threshold was found to be ≤411% (sensitivity and specificity 65% and 80%, respectively). …”
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Implementation and Tuning of Momentum-Based Controller for Standing Balance in a Lower-Limb Exoskeleton With Paraplegic User by A. Vallinas Prieto, A. Q. L. Keemink, E. H. F. van Asseldonk, H. van der Kooij

“…We first investigate how gain tuning of the center of mass tracking control law, part of a multi-objective optimal controller, affects balancing performance. …”
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Multiangle Correlation Feature Extraction and Disease Prediction Model Construction for Patients With Post-Stroke Dysarthria by Ting Zhu, Shufei Duan, Huizhi Liang, Fujiang Li, Wei Zhang

“…Principal Component Analysis and Variance Inflation Factor were employed to optimize GRA-DBN model. Both proposed models achieved a high prediction accuracy, with an adjusted R2 value of 0.85 for GRA-DBN and 0.92 for optimised model. …”
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Analisis Pelaksanaan Family Development Session Bidang Sanitasi Program Keluarga Harapan di Kecamatan Lengayang by Dona Idola, Hafni Bachtiar, Abdiana Abdiana

“…Berdasarkan hasil penelitian disimpulkan jika pelaksanaan FDS sanitasi di Kecamatan Lengayang Pesisir Selatan belum berjalan optimal. Untuk itu perlu peningkatan komitmen dari pendamping untuk benar-benar melaksanakan FDS sesuai petunjuk, dan melakukan advokasi ke pemerintah kabupaten agar bisa mengeluarkan kebijakan khusus FDS Sanitasi.…”
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Cow urine as an organic nutrient source for hydroponic vegetable production by I Putu Sujana, Luh Putu Yuni Widyastuti, Ni Kadek Ema Sustia Dewi

“…The regression showed that the optimal concentration of cow bio urine might be higher than the present levels.…”
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Evaluation of Carboxymethyl Cellulose/Gelatin Hydrogel-Based Dressing Containing Cefdinir for Wound Healing Promotion in Animal Model by Zahra Soleimani, Hadi Baharifar, Najmeh Najmoddin, Kamyar Khoshnevisan

“…The skin serves as a critical barrier against external pathogens, and its wound healing is a complex biological process that requires careful management to ensure optimal tissue regeneration. Hydrogels, a class of hydrophilic polymers, have emerged as promising materials for wound dressings due to their biocompatibility, biodegradability, and ability to create a moist wound environment conducive to cell proliferation and migration. …”
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Inadequate soft tissue coverage and bone loss/comminution are the typical risk factors of surgical site infection in open fractures of the hand: A nomogram prediction model. by Tianyang Jia, Jinglan He, Cunliang Miao, Yubin Long, Qi Dong, Jialiang Guo, Wei Chen, Zhiyong Hou

“…Hosmer-Lemeshow (H-L) test revealed optimal consistency between the probability of prediction model and the actual probability (training group: X2 = 5.706, P = 0.680; test group: X2 = 3.886, P = 0.867). …”
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Prediction of Insulin Resistance and Impaired Fasting Glucose Based on Sex Hormone-Binding Globulin (SHBG) Levels in Polycystic Ovary Syndrome by Aleksandra Biernacka-Bartnik, Piotr Kocełak, Aleksander Jerzy Owczarek, Piotr Choręza, Monika Puzianowska-Kuźnicka, Leszek Markuszewski, Paweł Madej, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…IFG and IR assessed based on HOMA-IR values > 2.0 were found in 19.5% and 47.8% of the study group, respectively. Empirical optimal cutoff values for SHBG levels were ≤41.5 nmol/L typical for IR (AUC 0.711, sensitivity 61.1%, specificity 71.6%, positive predictive value (PPV) 70.7%, and negative predictive value (NPV) 62.1%). …”
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Maternal and Fetal Outcomes in Women with Diabetes in Pregnancy Treated before and after the Introduction of a Standardized Multidisciplinary Management Protocol by Maddalena Morlando, Fabiana Savoia, Anna Conte, Antonio Schiattarella, Marco La Verde, Michela Petrizzo, Mauro Carpentieri, Carlo Capristo, Katherine Esposito, Nicola Colacurci

“…Currently, there is no consensus on the optimal management strategies for the follow-up and the timing of delivery of pregnancies affected by gestational and pregestational diabetes, with different international guidelines suggesting different management options. …”
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Reference intervals of inhibin B in Chinese children on chemiluminescence analyzer by Bin Zhou, Jinjun Luo, Xiang Dai, Xuelian He, Hui Yao

“…Compared to the boys, girls had lower median concentrations and variability in INHB across all four age groups. The optimal models for the effect of age on INHB were cubic (R2 = 0.440 for boys and R2 = 0.198 for girls). …”
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Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy by Fangzhou He, Jiuhui Xu, Fanwei Zeng, Boyang Wang, Yi Yang, Jie Xu, Xin Sun, Tingting Ren, Xiaodong Tang

“…Methods Since novel immunotherapies may address this need, we performed an integrative analysis involving single-cell RNA sequencing, cell function experiments, and humanized models to dissect the immunoregulatory interactions in EwS and identify strategies for optimizing immunotherapeutic efficacy. Results EwS is infiltrated by immunosuppressive myeloid populations, T and B lymphocytes, and natural killer cells. …”
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Pre-operative Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios as Predictors of Morbidity and Mortality in Diabetic Foot Infection Amputation Patients by Joseph Paulo Sales, Emiliano Tablante

“…Based on Youden’s index, the optimal cutoff points of neutrophil-lymphocyte and platelet-lymphocyte ratios were 7.27 and 32.40, respectively. …”
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Level measurement, regional variations, and the dynamic evolution of active aging in China—analysis based on CHARLS tracking data by Jiru Guo, Xiaoli Zhang, Xiaoli Zhang, Longyin Chen, Hong Yang

“…While the eastern region exhibits uneven development, the central and western regions have generally had more balanced growth.DiscussionTo improve the level of active aging among older adult individuals in China, policymakers should continuously optimize policies and pay more attention to the economic status and social participation of the older adult. …”
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Promoting Immortalized Adipose-Derived Stem Cell Transdifferentiation and Proliferation into Neuronal-Like Cells through Consecutive 525 nm and 825 nm Photobiomodulation by Madeleen Jansen van Rensburg, Anine Crous, Heidi Abrahamse

“…Research has shown that this process may be optimized by the introduction of laser irradiation in the form of photobiomodulation (PBM) to cells. …”
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Power flow and power quality improvement of a residential-industrial microgrid using 72-pulse inverter-based UIPC by Mahyar Abasi, Ali Nahavandi, Javad Ebrahimi, Gevork B. Gharehpetian

“…The design presented in this work was modeled and implemented in MATLAB software, and the results of different test scenarios validated the optimal performance of the suggested design.…”
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