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26761
Limits of the Turkish Model Applicability in the Middle East Countries after the Arab Awakening: The Case of Egypt
Published 2020-11-01“…The author emphasizes that initially this model was aimed at identifying the optimal balance between religious and secular principles in public life. …”
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26762
The Association of Arterial Pulse Wave Velocity with Internal Carotid Artery Blood Flow in Healthy Subjects: A Pilot Study
Published 2024-07-01“…The lack of correlation between cfPWV and ICA blood flow parameters suggests that the ICA may dilate as a compensatory mechanism to mitigate the effects of increased arterial stiffness, ensuring optimal cerebral blood flow in healthy individuals.…”
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26763
Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics
Published 2025-06-01“…A dataset of 76 antiviral drugs was prepared and optimized for analysis. Through the application of network pharmacology, gene ontology, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, this study identified Human Epidermal Growth Factor Receptor 2 (HER2) and Poly [ADP ribose] polymerase 1(PARP-1) as key targets involved in the molecular pathways associated with breast cancer. …”
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26764
Bimatoprost Intracameral Implant (Durysta®): A New Era in Glaucoma Management Through Sustained-Release Innovation
Published 2025-01-01“…However, repeat administrations are associated with adverse effects such as endothelial cell loss, highlighting the need for optimized re-dosing schedules. Future research should explore its use in advanced glaucomas, cost-effectiveness, and combination with other IOP-lowering treatments. …”
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26765
Parental wellbeing, parenting, and child mental health in families with young children in Arghakhanchi, Nepal
Published 2025-01-01“…Conclusion The results partially support the mediational model that Nepali parents’ well-being (especially in mental health symptoms, social support, and perception of family’s social class domains) is associated with less optimal parenting and, in turn, greater child mental health problems and lower social competence. …”
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26766
Equity of human resource allocation in centers for disease control and prevention in China based on agglomeration degree
Published 2025-01-01“…Objective: To evaluate the equity of human resource allocation in centers for disease control and prevention (CDCs) in China, so as to provide insights into optimizing human resource and promoting the high-quality development of CDCs. …”
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26767
Female Sex as a Thromboembolic Risk Factor in the Era of Nonvitamin K Antagonist Oral Anticoagulants
Published 2020-01-01“…Interestingly, NOACs seem to normalize the differences between males and females both in terms of safety and efficacy, whereas residual higher stroke risk and systemic embolism persist in AF women treated with vitamin K antagonist anticoagulants VKA with optimal time in therapeutic range. Based on the CHA2DS2-VASc score, NOACs represent the preferred choice in NVAF patients. …”
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26768
Sociodemographic characteristics, occupational characteristics, motivational factors, and job satisfaction among primary health service practitioners
Published 2025-02-01“…Establishing scientific and reasonable research on the incentive mechanism at grassroots medical institutions can help stabilize the team, enhance staff satisfaction and work performance, and optimize human resource utilization.…”
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26769
The volatilome – investigation of volatile organic metabolites (VOM) as potential tumor markers in patients with head and neck squamous cell carcinoma (HNSCC)
Published 2018-07-01“…At first, the procedure was optimized in respect to the extraction parameters. …”
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26770
A EVALUASI KONDISI GEDUNG GEREJA DI JAKARTA BARAT DENGAN METODE CONDITION SURVEY PROTOCOL (CSP) 1
Published 2025-01-01“…Hal ini disebabkan oleh faktor cuaca, kualitas material, usia bangunan, perencanaan pemeliharaan yang belum optimal dan faktor biaya yang menjadi kendala bagi gereja yang jemaatnya sedikit. …”
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26771
Evaluation of Drug Use Pattern in Emergency Department of Dilchora Referral Hospital, Dire Dawa, Ethiopia
Published 2020-01-01“…The findings of this study revealed that the drug utilization pattern was not optimal in accordance with the standard values of WHO prescribing indicators. …”
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26772
Daratumumab for autoimmune diseases: a systematic review
Published 2023-12-01“…Adverse events were reported in 45% of patients including application-associated reaction (20%), infection (19%) and hypogammaglobulinaemia (33%).Conclusion Targeting CD38 via daratumumab is a new promising therapeutic option in therapy refractory autoimmune diseases. Efficacy as well as optimal therapeutic regimen and management or prevention of adverse events require further investigation. …”
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26773
Systemic reviews and meta-analysis of the use of midodrine in hepatorenal syndrome
Published 2024-09-01“…However, significant, well-designed clinical trials are needed to determine optimal dosage, duration, and pharmacological side effects. …”
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26774
Development of prognostic models for HER2-positive metastatic breast cancer in females: a retrospective population-based study
Published 2024-12-01“…Stratification was evaluated using Kaplan–Meier curves and log-rank tests based on optimal total score cut-off values. We published web-based versions of these nomograms for clinical use. …”
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26775
The Epidemiology, Burden, Risk Factors, Presentations, and Challenges of Evaluating and Managing Patients with Pulmonary Hypertension in Nigeria – A Short Review
Published 2024-12-01“…The current clinical management typically focuses on symptom management and optimizing supportive care. The challenges encountered in the management of pulmonary hypersensitivity pneumonitis in Nigeria include limited access to specialized health-care facilities, lack of awareness among health-care professionals and the general population, inadequate diagnostic tools and resources, and financial constraints. …”
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26776
Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria
Published 2025-01-01“…A treosulfan/fludarabine-based regimen is recommended; however, there is no consensus on optimal drug selection.…”
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26777
Effects of Homogeneous Doping on Electron–Phonon Coupling in SrTiO<sub>3</sub>
Published 2025-01-01“…In spite of the strong implications these reports have on specifying the pairing glue, they have not proved sufficient in explaining the magnitude of the optimal doping. This motivated us to apply density functional theory to Nb-doped STO to analyze how the phonon band structures and the electron–phonon coupling evolve with doping. …”
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26778
Effectiveness of post-harvest treatments for Manzanilla table olives and the suitability of Hojiblanca as a substitute for mechanical harvesting
Published 2025-03-01“…This study highlights the importance of PHFT and cultivar selection in optimizing quality and consumer satisfaction in mechanically harvested table olive production.…”
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26779
CD73/adenosine dynamics in treatment-induced pneumonitis: balancing efficacy with risks of adverse events in combined radio-immunotherapies
Published 2025-01-01“…By understanding these dynamics, we aim to inform future strategies for optimizing radio-immunotherapy regimens, ensuring effective cancer control while preserving pulmonary integrity and patient quality of life.…”
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26780
Validity and Reliability of Dynamic and Functional Balance Tests in People Aged 19-54: A Systematic Review
Published 2024-04-01“…This review equips healthcare professionals with valuable insights into optimal balance assessment methods for the healthy, 19 to 54 aged population…”
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