Comparison of diet and exercise on cardiometabolic factors in young adults with overweight/obesity: multiomics analysis and gut microbiota prediction, a randomized controlled trial by Zongyu Lin, Tianze Li, Fenglian Huang, Miao Wu, Lewei Zhu, Yueqin Zhou, Ying‐An Ming, Zhijun Lu, Wei Peng, Fei Gao, Yanna Zhu

“…Abstract The optimal strategy for improving cardiometabolic factors (CMFs) in young obese individuals through diet and exercise remains unclear, as do the potential mechanisms. …”
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Hydrometallurgical Recovery of Copper from Computer-Printed Circuit Boards by Abdol Jani Wan Nur Fazlina, Abdul Rani Noor Hidayu, Mohamad Nor Fadilah, Sayed Jamaludin Sharifah Iziuna

“…Acidic leaching with a 1% (w/v) e-waste pulp density resulted in higher Cu extraction from PCB board waste compared to USB jack and capacitor waste. The optimal recovery of Cu achieved was 2207 mg/L after 20 minutes of leaching, using a particle size of 10 mm, at 100°C, 150 rpm, and a pulp density of 1% (w/v). …”
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Characterization and simulation of AlGaN barrier structure effects in normally-off recessed gate AlGaN/GaN MISHEMTs by An-Chen Liu, Hsin-Chu Chen, Po-Tsung Tu, Yan-Lin Chen, Yan-Chieh Chen, Po-Chun Yeh, Chih-I Wu, Shu-Tong Chang, Tsung-Sheng Kao, Hao-Chung Kuo

“…The objective of this study is to optimize the trade-off between threshold voltage (V _TH ) and maximum drain current (I _D,max ) in recessed gate AlGaN/GaN metal insulator semiconductor high electron mobility transistor (MISHEMT) using atomic layer etching (ALE) technology, with technical computer-aided design (TCAD) simulations assisting in the analysis of the underlying mechanisms to demonstrate the high performance and reliability of GaN-based power application. …”
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Differences in physicochemical properties and proteomics analysis of spray- and freeze-dried milk powders from bovine, goat, and horse sources by Shichu Zhou, Xin Zhang, Junyu Zhang, Changjiang Zang, Rongbo Fan, Jun Wang, Tongjun Guo, Rongwei Han, Yongxin Yang

“…These findings contribute to a deeper understanding of the differences in the physicochemical properties and potential biological functions of spray- and freeze-dried milk powders from various sources, which may help in further optimizing specific milk powder processing technologies.…”
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Image Comparison on T2 Qtse Lumbal Examination using Grappa Technique with and without Magnetization Transfer Contrast in Degenerative Disc Disease Case by Karina Sandra Arief Apriliani, Sri Andreani Utomo, Muhaimin, Lailatul Muqmiroh

“…This technique needs to be followed by setting other parameters to produce an optimal image, namely by applying Magnetization Transfer Contrast (MTC). …”
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In vitro study of resveratrol as an antioxidant for boar semen preservation: A systematic review by Ragil Angga Prastiya, Trilas Sardjito, Amung Logam Saputro, Sari Yanti Hayanti, Nining Haryuni, Samira Musa Sasi

“…This study highlights the need for further research to optimize RVT dosage and application methods for different semen preservation techniques.…”
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Numerical exploration and thermal criticality of a dual exothermic reaction with radiative heat loss in co-axial cylinder configurations by R.A Oderinu, S.O. Salawu, A.D. Ohaeghue, S. Alao, E.I. Akinola, J.A. Owolabi

“…Due to their enormous importance, efficient and optimal performance in industrial applications heavily rely on the proper handling, maintenance, and management of reacting systems, particularly exothermic reactions. …”
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Early Detection of Multiwavelength Blazar Variability by Hermann Stolte, Jonas Sinapius, Iftach Sadeh, Elisa Pueschel, Matthias Weidlich, David Berge

“…Together with simultaneous measurements at lower energies, the very-high-energy (VHE) emission observed during blazar flares may be used to probe the population of accelerated particles. However, optimally triggering observations of blazar high states can be challenging. …”
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High Throughput Quantitative Bioanalytical LC/MS/MS Determination of Gemifloxacin in Human Urine by Adnan A. Kadi, Rihab F. Angawi, Mohamed W. Attwa, Hany W. Darwish, Ali Saber Abdelhameed

“…Urine samples were filtered through a Millex-GP, 0.22 μm syringe filter. Optimal chromatographic separation of the analytes was achieved on Zorbax SB-C18 (30 mm × 2 mm i.d., 3.5 μm maintained at ambient temperature). …”
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Taming of trinitromethyl-oxadiazole to access high density and high oxygen balance via a dual modulation strategy by Jinya Zhang, Teng Fei, Jingwei Meng, Jinxiong Cai, Lei Zhang, Siping Pang, Chunlin He

“…In this work, an effective dual modulation strategy involving both molecular isomerization and crystal morphology control was employed to design and optimize trinitromethyl-oxadiazole with improved comprehensive performance. …”
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Unveiling the molecular profile of a prostate carcinoma: implications for personalized medicine by Massimiliano Agostini, Erica Giacobbi, Francesca Servadei, Julia Bishof, Likas Funke, Giuseppe Sica, Valentina Rovella, Marco Carilli, Valerio Iacovelli, Yufang Shi, Jianquan Hou, Eleonora Candi, Gerry Melino, Giulio Cervelli, Manuel Scimeca, Alessandro Mauriello, Pierluigi Bove

“…The omics profiling integrating hypoxia, ROS and the anti-cancer immune response, optimizes therapeutic strategies and advances personalized care for prostate cancer patients. …”
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Subthalamic Nucleus Deep Brain Stimulation in Early Stage Parkinson’s Disease Is Not Associated with Increased Body Mass Index by Sarah H. Millan, Mallory L. Hacker, Maxim Turchan, Anna L. Molinari, Amanda D. Currie, David Charles

“…Subjects were randomized to DBS plus optimal drug therapy (DBS+ODT; n=15) or ODT (n=14) and followed for 24 months. …”
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Early-life enrichment in American mink (Neogale vison): Enrichment of the perinatal environment improves maternal nest building and reduces stereotypic behaviour by Gabrielle B Clark, María Díez-León, Rebecca K Meagher

“…Further, these materials may not produce optimal nest structures for the rearing of kits. In the present study, we provided extra, relatively high-quality nest-building materials and a chewable sisal rope enrichment for mink dams in the perinatal period (a group enriched at whelping; EW). …”
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Digitalisation to zero-waste: the interplay of open eco-innovation and the circular economy in agricultural enterprises by Wutthiya Aekthanate Srisathan, Wongsatorn Worrakittikul, Kanokon Rattanapon, Thippayarat Hongto, Apichai Phrommasakha Na Sakhonnakon, Phaninee Naruetharadhol

“…However, established firms demonstrate strengths in optimizing existing process for sustainability. The findings highlight the critical role of innovative digital practices in promoting sustainable ecosystems and addressing the urgent need for near-zero-waste strategies in agriculture. …”
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Evidence-based Algorithms for Free Deep Inferior Epigastric Perforator Flap Salvage in Autologous Breast Reconstruction by Anna R. Todd, MD, PhD, FRCSC, Mawaddah Alrajraji, MD, Kathryn Sawa, MD, Joan E. Lipa, MD, MSc, Laura Snell, MD, MSc

“…The first algorithm outlines perioperative management strategies to optimize patient care and prompt return to the OR. …”
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Insights into hydraulic conductivity, mechanical properties, and microstructure of fly ash-modified clay anti-seepage layer to red mud leachate by Yibo Zhang, Yujie Ding, Yulong Wang, Yue Yu, Qian Chen, Zheng Wu

“…It also enhances the liners' ability to adsorb heavy metal ions and increases their mechanical strength, especially cohesion, with optimal performance at a 9 % fly ash content. The study further reveals that pozzolanic reactions in the alkaline environment of red mud lead to the formation of cementitious gel binders (C-S-H, C-A-H), which reduce pore sizes and create a denser, more impermeable structure. …”
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Identification of reproductive performance in Bali-polled bulls using computer-assisted semen analysis and plasma seminal proteomics by Athhar Manabi Diansyah, Sanstoso Santoso, Herdis Herdis, Muhammad Yusuf, Tri Puji Priyatno, Tulus Maulana, Abdul Latief Toleng, Muhammad Ihsan Andi Dagong, Syahruddin Said, Hikmayani Iskandar, Aeni Nurlatifah, Puji Lestari, Lukman Affandy, Abdullah Baharun

“…Background and Aim: Bali-polled bulls, known for their favorable traits, require advanced reproductive performance analysis to optimize breeding programs. This study aimed to evaluate sperm kinematics and seminal plasma proteomic profiles as biomarkers for sperm motility and fertility in Bali-polled bulls. …”
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Rating pome fruit quality traits using deep learning and image processing by Nhan H. Nguyen, Joseph Michaud, Rene Mogollon, Huiting Zhang, Heidi Hargarten, Rachel Leisso, Carolina A. Torres, Loren Honaas, Stephen Ficklin

“…Abstract Quality assessment of pome fruits (i.e. apples and pears) is used not only for determining the optimal harvest time but also for the progression of fruit‐quality attributes during storage. …”
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The influence of macroscopic pedestrian structures on train boarding efficiency by Rabia I. Kodapanakkal, Caspar A.S. Pouw, Antal Haans, Jaap Ham, Gunter Bombaerts, Alessandro Corbetta, Andrej Dameski, Andreas Spahn, Federico Toschi

“…Although people generally adhere to this norm, the way it is executed may not be optimal for deboarding efficiency. We investigate how waiting boarders form a deboarding channel (a corridor where deboarders exit the train) and how this channel in turn influences the efficiency of deboarding. …”
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Synthesis and application of optical silver nanoparticles capped carbon dots as dual-mode sensors for trivalent chromium ions in dietary supplements by Ratchadaporn Seedad, Pornpimol Prayongpan, Wutthikrai Busayaporn, Kriangsak Songsrirote

“…The nanocomposite showed maximum absorption wavelength at 406.0 nm, while emission wavelength appeared at 526.0 nm when excited at 406.0 nm. Optimal conditions for the Ag@CDs activity on Cr3+ ion detection were at pH 6, volume ratio between Ag@CDs and Cr3+ ion of 1.0:4.0, and reaction time of 20 min. …”
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