Optimum design of wind turbine foundation according to rebar detailing by Italo Linhares Salomão, Placido Rogério Pinheiro, Napoleão Vieira Nepomuceno, Gabriel Xavier Santiago Marinho, Matheus Martins Palmela Bastos de Oliveira, Joel J.P.C. Rodrigues, Bruno Ricardo de Almeida

“…The proposed model consists of three phases: the first involves a non-linear regression to obtain an equation that represents the bending moments at any point in the foundation; the second applies a linear quadratic model to choose the ideal layout of the calculation sections; and the third uses a binary integer linear model to determine the ideal diameter of the bars and their consequent positioning. This search for optimality must comply with the restrictions imposed by normative criteria, including maximum bar lengths and rebar lap splices, maintaining good constructability based on standardisation. …”
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Exogenous Melatonin Boosts Heat Tolerance in <i>Rosa hybrida</i> via <i>RhCOMT1</i> Modulation by Chenyang Li, Zhiyin Ding, Zipeng Cai, Yongying Ruan, Peitao Lü, Yang Liu

“…Here, we observed that <i>R. hybrida</i> in vitro plantlets supplemented with melatonin in the culture medium exhibited higher chlorophyll content, relative ion leakage, and fresh weight after 12 d of high-temperature treatment; the optimal concentration was established at 5 mg/L. Using molecular and biochemical techniques, we explored the roles of a melatonin synthase gene <i>RhCOMT1</i>, which expression was influenced by heat stress and melatonin. …”
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Leveraging LLMs and wearables to provide personalized recommendations for enhancing student well-being and academic performance through a proof of concept by Arfan Ahmed, Sarah Aziz, Alaa Abd-alrazaq, Rawan AlSaad, Javaid Sheikh

“…Abstract Traditional one-size-fits-all recommendations for student well-being and academic success may not be optimal. Personalized recommendations based on individual data hold promise. …”
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Experience of diagnosis and surgical treatment of cardiac myxomas by R.M. Vitovskyi, V.V. Isaіenko, A.R. Vitovskyi, O.A. Pishchurin, V.V. Grabarchuk, O.V. Satmari

“…Conclusions. The issues of optimal tactics for patients with CM consist of urgent diagnosis and surgical intervention, which ensures the effectiveness of treatment of CM, which is confirmed by the data of long-term results. …”
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Association between guidelines and medical practitioners’ perception of best management for patients attending with an apparently uncomplicated acute sore throat: a cross-sectional... by Alastair D Hay, Mark H Ebell, Ronny Gunnarsson, Pär-Daniel Sundvall, Katarina Hedin, Hannelore Wächtler, Naveen Manchal, Lynne Reid, Stefan Malmberg, Sean Hawkey

“…Objective To investigate the relationship between guidelines and the medical practitioners’ perception of optimal care for patients attending with an apparently uncomplicated acute sore throat in five countries (Australia, Germany, Sweden, UK and USA).Design International cross-sectional survey.Setting Primary healthcare (PHC).Participants Medical practitioners working in PHC.Main outcome measures ORs for: (A) perception of throat swabs as important, (B) perception of blood tests (C reactive protein, B-ESR and B-leucocytes) as important and (C) antibiotic prescriptions if no pathogenic bacteria isolated on throat swab.Results Guidelines differed significantly; those recommending throat swabs (Sweden and USA) were associated with practitioners perceiving them as important. …”
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Feature selection enhances peptide binding predictions for TCR-specific interactions by Hamid Teimouri, Hamid Teimouri, Zahra S. Ghoreyshi, Zahra S. Ghoreyshi, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Jason T. George, Jason T. George, Jason T. George, Jason T. George

“…A broad range of physicochemical properties, including amino acid composition, dipeptide composition, and tripeptide features, were integrated into the machine learning-based feature selection framework to identify key properties contributing to binding affinity.ResultsOur analysis reveals that leveraging optimized feature subsets not only simplifies the model complexity but also enhances predictive performance, enabling more precise identification of TCR peptide interactions. …”
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The Effects of Destemming/Crushing and Pressing Conditions in Rosé Wine Production by Lorenzo Guerrini, Ferdinando Corti, Giulia Angeloni, Piernicola Masella, Agnese Spadi, Luca Calamai, Alessandro Parenti

“…This represents a useful tool to optimize grape processing according to the company’s commercial priorities.…”
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99mTc-labeled benzenesulfonamide derivative-entrapped gold citrate nanoparticles as an auspicious tumour targeting by Adli A. Selim, Tamer M. Sakr, Basma M. Essa, Galal H. Sayed, Kurls E. Anwer

“…The nano-platform was successfully produced with good stability, optimal particle size (9 nm diameter for AuNPs), and high radiochemical purity for [99mTc]Tc-compound 3 (88.31 ± 2.14%). …”
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Performance of twisted tape absorber-based photovoltaic thermal systems in clockwise and counterclockwise configurations by Abdalrahman M.O. Al-Karboly, Adnan Ibrahim, Anas Al-Tarabsheh, Anwer B. Al-Aasam, Ali H.A. Al-Waeli, Ahmad Fazlizan, Kamaruzzaman Sopian

“…These findings advance the understanding of PVT system performance and open new avenues for optimizing renewable energy technologies, making this research a valuable contribution to the field.…”
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Multiband Planar Inverted-F Antenna with Independent Operating Bands Control for Mobile Handset Applications by Mustapha El Halaoui, Abdelmoumen Kaabal, Hassan Asselman, Saida Ahyoud, Adel Asselman

“…The PIFA occupies a small volume of 51 × 14 × 7.2 mm3 and is placed on the top portion of mobile phone. The optimized PIFA is worked in the 790 MHz band (737–831 MHz), the 1870 MHz band (1794–1977 MHz), the 2550 MHz band (2507–2615 MHz), and the 3400 MHz band (3341–3545 MHz), to cover LTE700, LTE800, DCS1800, PCS1900, LTE1800, LTE1900, LTE2500, and WIMAX3400 bands. …”
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Costs analysis of integrating group interpersonal therapy into HIV care services in Senegal by Yao Abounan, Jérôme Wittwer, Judicaël Malick Tine, Ibrahima Ndiaye, Salaheddine Ziadeh, Sophie Desmonde, Hélène Font, Helen Verdeli, Ndeye Fatou Ngom, Nathalie de Rekeneire, Antoine Jaquet, Moussa Seydi, Charlotte Bernard, the IeDEA West Africa Cohort Collaboration

“…This preliminary work should enable policymakers to identify the optimal resources to be mobilized to implement and ensure the sustainability of this therapy in HIV at a country-level program.…”
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Exploring adherence in patients with advanced breast cancer: focus on CDK4/6 inhibitors by Baković Matea, Bago Martina, Benić Lucija, Krajinović Magdalena, Silovski Tajana, Plavetić Natalija Dedić, Turković Lu, Sertić Miranda, Hadžiabdić Maja Ortner

“…Treatment adherence is crucial for optimal outcomes in advanced breast cancer, but can be challenging due to various factors, i.e. patients’ attitudes and behavior upon diagnosis, and complex therapies with high adverse effect rates. …”
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Real-world pharmacovigilance study of drug-induced autoimmune hepatitis from the FAERS database by Bu-kun Zhu, Si-ying Chen, Xiang Li, Shu-yun Huang, Zhan-yang Luo, Wei Zhang

“…This study provides evidence-based insights into implicated drugs, aiming to optimize clinical management and mitigate risks.…”
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Knowledge Distillation-Enhanced Behavior Transformer for Decision-Making of Autonomous Driving by Rui Zhao, Yuze Fan, Yun Li, Dong Zhang, Fei Gao, Zhenhai Gao, Zhengcai Yang

“…On one hand, RL’s policy networks often lack sufficient reasoning ability to make optimal decisions in highly complex and stochastic environments. …”
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Therapeutic potential of bisphosphonates - review of medical indications, mechanism of action, interactions and adverse effects by Agnieszka Mikosińska, Mateusz Litwin, Jakub Parys, Patrycja Kałuziak, Aleksandra Witek, Martyna Kaźmierczak, Stanisław Jesionek, Marta Jajczak, Maciej Mossakowski

“…This review provides healthcare professionals with evidence-based, scientifically validated information on bisphosphonates, while also identifying critical areas for further investigation to optimize their safety and efficacy, ultimately improving patient outcomes and quality of life. …”
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Advancements in photovoltaic efficiency: The role of fluorine-doped CZTS in homojunction solar cells by Milad Yousefizad, Zohreh Golshan Bafghi, Amirmohammad Shahriyari, Andia Javanmardi, Naser Hakimi Raad, Ashraf Ahmadi Shadmehri, Siavosh Samoodi, Negin Manavizadeh, Ali Moafi

“…The efficiency of the solar cell is optimized considering the thickness of the p-CZTS layer, which saturates at 21.8 % beyond 5 μm thickness. …”
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QbD-Driven preparation, characterization, and pharmacokinetic investigation of daidzein-l oaded nano-cargos of hydroxyapatite by Namrata Gautam, Debopriya Dutta, Saurabh Mittal, Perwez Alam, Nasr A. Emad, Mohamed H. Al-Sabri, Suraj Pal Verma, Sushama Talegaonkar

“…The developed nanoparticles were optimized by "Design-Expert" software and underwent comprehensives in-vitro and in-vivo characterizations. …”
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Regional Boundary Control of Traffic Network Based on MFD and FR-PID by Xin Yang, Juncheng Chen, Mantun Yan, Zhao He, Ziyan Qin, Jiandong Zhao

“…The results show that the control effect of the proposed method is better than that of the traditional method, and the regional average accumulative vehicle number, regional average completed volume, regional accumulative delays, and total vehicle travel time are optimized by 28.21%, 41.19%, 27.06%, and 32.73%, respectively. …”
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Theta transcranial alternating current stimulation over the prefrontal cortex enhances theta power and working memory performance by Ranjan Debnath, Osama Elyamany, Osama Elyamany, Jona Ruben Iffland, Jonas Rauh, Michael Siebert, Elisa Andraes, Gregor Leicht, Christoph Mulert, Christoph Mulert

“…Furthermore, the results suggest that 5 Hz tACS enhances response speed by elevating task-related activity in the prefrontal cortex to an optimal level for task performance.ConclusionIn summary, the findings highlight the potential of tACS as a technique for modulating specific brain oscillations, with implications for research and therapeutic interventions.…”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2003 by Denis E O’donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy D Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Francois Maltais, Jeremy Road

“…The main goal of the Canadian Thoracic Society (CTS) Evidence-Based Guidelines is to optimize early diagnosis, prevention and management of COPD in Canada. …”
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