Utilizing ATLS® Trauma Management Protocols: The Gold Standard for Safe and Effective Care. by Agron Dogjani, Edvin Selmani, Edmond Zaimi, Kastriot Haxhirexha, Petrit Biberaj, Basri Lenjani, Kastriot Subashi, Ilir Hasmuca, Erjona Zogaj, Amarildo Blloshmi, Klevis Doci

“…Through multidisciplinary collaboration and continuous training, healthcare teams are equipped to deliver coordinated and efficient care, optimizing patient outcomes. In conclusion, using ATLS trauma management protocols represents more than a guideline; it embodies a commitment to excellence in patient care. …”
Get full text

Current virtual reality-based rehabilitation interventions in neuro-developmental disorders at developmental ages by Micaela Capobianco, Concetto Puzzo, Concetto Puzzo, Concetto Puzzo, Chiara Di Matteo, Alberto Costa, Alberto Costa, Walter Adriani, Walter Adriani, Walter Adriani

“…Specifically, in individuals with ADHD, VR showed benefits in attention and executive function, with optimal results when combined with pharmacological treatments. …”
Get full text

Prevalence and natural development of thoracolumbar kyphosis in achondroplasia: A systematic review and meta-analysis by Chady Omara, Rania A. Mekary, Carmen L.A. Vleggeert-Lankamp

“…There is however no consensus on the optimal treatment, due to limited data on diagnostic criteria, the natural development and the prevalence of TLK. …”
Get full text

Design and fabrication of {111}-textured nanotwinned silver coating for enhancing surface wear resistance of depleted uranium by Kunming Yang, Xiaobo Wang, Shengfa Zhu, Yawen Zhao, Qingdong Xu, Yiyun Wei, Chao Lu, Zhiyuan Wen, Tongxiang Fan, Mingyu Gong, Anyi Yin, Wenhua Luo

“…Microstructural characterizations showed that at the optimized bias voltage of −400 V, the sputter-deposited Ag coating exhibited {111}-oriented texture with high-density nanoscale twins and also well-bonded Ag/DU interface with an UO2 interlayer, thus endowing the Ag coating highly stable wear resistance with low mass wear rate of ∼1.37 × 10−7 g/(N·s). …”
Get full text

Anchored and epoxied ferrocement strips for improving flexural performance of two-way reinforced concrete slabs by Galal Elsamak, Mohamed Ghalla, Moataz Badawi, Abdullah Albogami, Taher A. Tawfik, Ramy I. Shahin

“…By replacing a portion of the slab's concrete cover with ferrocement strips, this method aims to enhance the load-carrying capacity, ductility, and crack resistance of the slabs while optimizing material usage and minimizing additional weight. …”
Get full text

Visible-Light-Driven Degradation of Chloramphenicol Using CeO₂ Nanoparticles Prepared by a Supercritical CO₂ Route: A Proof of Concept by Maria Chiara Iannaco, Antonietta Mancuso, Stefania Mottola, Andrea Pipolo, Vincenzo Vaiano, Iolanda De Marco

“…Furthermore, the impact of catalyst dosage and chloramphenicol concentration was investigated. Under optimal reaction conditions (25 mg L⁻¹ chloramphenicol and 2.25 g L⁻¹ catalyst dosage), a degradation efficiency of 64% was achieved. …”
Get full text

Coseismic deformation and seismogenic structure of the 2024 Hualien Earthquake measured by InSAR and GNSS by Jiangtao Qiu, Lingyun Ji, Liangyu Zhu, Yongsheng Li, Chuanjin Liu, Qiang Zhao

“…The fault geometry parameters, obtained through the inversion of an elastic half-space homogeneous model, indicated an optimal fault strike of 196°, a dip angle of 30.9°, and an average strike-slip of 0.4 ​m and dip-slip of −2.6 ​m. …”
Get full text

Polysaccharide-based biomaterials for regenerative therapy in intervertebral disc degeneration by Xin Wang, Yixue Huang, Yilin Yang, Xin Tian, Yesheng Jin, Weimin Jiang, Hanliang He, Yong Xu, Yijie Liu

“…This review delineates the potential of various polysaccharides during the fabrication of hydrogels and scaffolds for disc regeneration, guiding and inspiring future research to focus on optimizing these materials for clinical translation for IVDD repair and regeneration.…”
Get full text

Synergistic effects of CO2 sequestration on mechanical, microstructural, and environmental performance in carbonated MgO-based ECC by Zihao Song, Rui Chen, Tianyu Wang, Haoliang Wu

“…The study concludes that increasing MgO content enhances both the sustainability and mechanical resilience of carbonated MgO-based ECC, though optimal dosing is necessary to balance strength gains with dimensional stability. …”
Get full text

Anterior Knee Pain and Knee Functional Scores Following Common Approaches to Tibial Shaft Fractures by Sarthak Parikh, DO, Laurel Marsh, BS, Mateao Anderson, BS, Jeremy Scott, DO, Amar Patel, DO, Christopher Hendrix, MD, Keivan Abtahi, DO

“…Further large, prospective trials are needed to clarify optimal approaches for tibial shaft fractures. Level of Evidence:. …”
Get full text

Bioaugmented design and functional evaluation of low damage implantable array electrodes by Ling Wang, Chenrui Zhang, Zhiyan Hao, Siqi Yao, Luge Bai, Joaquim Miguel Oliveira, Pan Wang, Kun Zhang, Chen Zhang, Jiankang He, Rui L. Reis, Dichen Li

“…In addition, the design, materials, and performance of the developed electrode was optimized through a combination of numerical simulations and physio-chemical characterizations. …”
Get full text

Toward improving precision and complexity of transformer-based cost-sensitive learning models for plant disease detection by Manh-Tuan Do, Manh-Hung Ha, Duc-Chinh Nguyen, Oscal Tzyh-Chiang Chen, Oscal Tzyh-Chiang Chen

“…The proposed model combined with transformer-based long-term dependency modeling and convolution-based visual feature extraction to improve object detection performance. To optimize a model to a lightweight version, we integrated the proposed transformer model with the Ghost module. …”
Get full text

Bread wheat callusogenesis and organogenesis using mature embryos as explants by G. R. Gumerova, A. A. Galimova, B. R. Kuluev

“…With this in view, the regeneration potential of two spring (‘Saratovskaya 55’ and ‘Sigma’) and three winter (‘Tanya’, ‘Fisht’ and ‘Pamyat’) cultivars of bread wheat was assessed, and optimal conditions were identified for callus induction and organogenesis using mature embryos.   …”
Get full text

First molecules to reactivate RASG12V GTPase activity by Aneta Wlodarczyk, Cezary Treda, Marcin Pacholczyk, Adrianna Rutkowska, Marta Wegierska, Amelia Kierasinska-Kalka, Katarzyna Wasiak, Damian Ciunowicz, Dagmara Grot, Pawel Glowacki, Ewelina Stoczynska-Fidelus, Piotr Rieske

“…Methods The compounds were initially identified through virtual screening, and their optimal binding conformation in the RAS SW-II pocket was determined using the flexible docking technique. …”
Get full text

Automatic Grape Cluster Detection Combining YOLO Model and Remote Sensing Imagery by Ana María Codes-Alcaraz, Nicola Furnitto, Giuseppe Sottosanti, Sabina Failla, Herminia Puerto, Carmen Rocamora-Osorio, Pedro Freire-García, Juan Miguel Ramírez-Cuesta

“…Yield estimation from these technologies is essential for optimizing resource allocation, improving harvest logistics, and supporting decision-making for sustainable vineyard management. …”
Get full text

Search for surrogate markers to predict end stage kidney disease in long term lithium users by M. J. van der Aa, A. A. Bonenkamp, U. M. H. Klumpers, R. W. Kupka, T. Nijenhuis, A. P. M. Kerckhoffs

“…In this narrative review the aim is to determine the optimal surrogate endpoint for ESKD in long-term lithium users in a scientific context. …”
Get full text

Elevated Serum Total Bilirubin Level Is Associated with Poor Outcomes in Pediatric Patients with Sepsis-Associated Liver Injury by Yun Cui, Yijun Shan, Rongxin Chen, Chunxia Wang, Yucai Zhang

“…Furthermore, the area under the receiver-operating characteristic (ROC) curve (AUC) for TBIL was 0.736 (95% confidence interval (CI): 0.614–0.858, P=0.001), in which the optimal cut-off value was 64.5 μmol/L. The combined index named “TBIL” and “TBA” showed an AUC of 0.745 (0.626–0.865) for predicting the prognosis in patients with SALI. …”
Get full text

Vacuum-Assisted Closure and Muscle Flap as An Alternative Modality for Infected Wound After Orif of Tibial Fracture: Case Report by OK Ilham Abdullah Irsyam, Saraswati Hastika, Hendra Hendra, Andrew Budiartha Budisantoso, Tesar Akbar Nugraha

“…Conclusion: Debridement with muscle flap and application of VAC in the deep infected wound of open reduction and internal fixation was found to be successful methods in minimizing complications and obtaining an optimal outcome. This finding was associated with accompanying morbidities or a good wound healing process.…”
Get full text

Impact of Different Sugar Syrups on the Development of the Fat Body in Worker Bees (<i>Apis mellifera macedonica</i>) by Svilen B. Lazarov, Petya M. Veleva, Atanas Z. Atanasov, Ivaylo S. Hristakov, Zlatko Puškadija

“…These findings provide practical guidance for beekeepers to optimize feeding strategies and support resilient bee colonies.…”
Get full text

Lower vicine content reduces the reproductive yield performance in faba bean (Vicia faba L.) by Sadhan Debnath, Mayank Rai, Wricha Tyagi, Sujan Majumder, Ng. Tombisana Meetei

“…Therefore, complete elimination of vicine or development of near-zero vicine faba bean could drastically reduce the yield potential of the crop, hence one has to be very cautious and follow efficient selection strategies while optimizing lower concentration of vicine for development of low vicine varieties. …”
Get full text