Expression and Function of the Homeostatic Molecule Del-1 in Endothelial Cells and the Periodontal Tissue by Jieun Shin, Kavita B. Hosur, Kalyani Pyaram, Ravi Jotwani, Shuang Liang, Triantafyllos Chavakis, George Hajishengallis

“…The reciprocal regulation between Del-1 and inflammation may contribute to optimally balance the protective and the potentially harmful effects of inflammatory cell recruitment.…”
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Study on the Vibration Propagation Law and Stress Distribution Characteristics in Double-Arch Tunnels During Blasting by Xiaofei Sun, Ying Su, Dunwen Liu, Yu Tang, Pei Zhang, Jishuang Hu, Xianghao Sun

“…The difference in vibration strength across different tunnel parts provides a basis for optimizing the structure. It helps strengthen the parts susceptible to vibration during the design stage of the multi-arch tunnel, improving the tunnel’s safety and stability.…”
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Assessment of Roof Tilt and Building Azimuth for Off-Grid Photovoltaic Power for Buildings in Metropolitan Lagos, Nigeria by Olaleye SALU, Ibikunle Ogundari, Samuel ANIH, John-Felix AKINBAMI

“…A five tier rooftop generation template of 245 MWp was consequently developed. Optimal roof tilt and building azimuth angles for the systems were estimated to be 5o and 180o respectively though combinations of azimuth and tilt angles not exceeding 30o tilt and 90o azimuth gave acceptable yields. …”
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Survival after Abdominoperineal and Sphincter-Preserving Resection in Nonmetastatic Rectal Cancer: A Population-Based Time-Trend and Propensity Score-Matched SEER Analysis by Rene Warschkow, Sabrina M. Ebinger, Walter Brunner, Bruno M. Schmied, Lukas Marti

“…APR was associated with an increased risk of cancer-specific mortality after unadjusted analysis (HR = 1.61, 95% CI: 1.28–2.03, P<0.01) and multivariable adjustment (HR = 1.39, 95% CI: 1.10–1.76, P<0.01). After optimal adjustment of highly biased patient characteristics by propensity-score matching, APR was not identified as a risk factor for cancer-specific mortality (HR = 0.85, 95% CI: 0.56–1.29, P=0.456). …”
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Design and study of valveless piezoelectric pump with streamlined chamber fishtail-type bluff body by Xiaochao Tian, Zhenming Wang, Kai Yang, Yang Bai, Yingyu Dai, Defeng Niu, Zhicheng Zhong

“…The fishtail-type bluff body is optimized with parameters, and the maximum output flow rate of the designed piezoelectric pump is 44.18 ml/min when the height is 2 mm. …”
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Modelling the Isotope composition of groundwater using hydrochemical properties in eastern Saudi Arabia: Implementation of innovative data intelligence techniques by Mohammed Benaafi, Waleed M. Hamanah, Ebrahim Al-Wajih

“…The optimum model for δ¹ ⁸O (O_M1) was achieved with R² of 0.9858, MAE of 0.0440, and Pearson correlation of 0.9941. for δ²H the optimal model (H_M1) was achieved with R² of 0.9317, MAE of 0.5334, and Pearson correlation of 0.9658. …”
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Impact of stock market indices and raw material prices on the yield movements of Caterpillar company securities by Petrović Nevena, Novićević-Čečević Bojana, Krstajić Goran

“…Such predictions contribute to a better understanding of the characteristics that enable optimal aggregation of information and efficient price determination. …”
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Surface topography modulates initial platelet adhesion to titanium substrata by Cecilia Yan Guo, Raymond Mo, Hugh Kim

“…The modification of surface topography is a widely-employed strategy for optimizing tissue integration with dental implants. …”
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Effect of ionic strength and mixing ratio on complex coacervation of soy protein isolate/Flammulina velutipes polysaccharide by Junmiao Zhang, Hengjun Du, Ning Ma, Lei Zhong, Gaoxing Ma, Fei Pei, Hui Chen, Qiuhui Hu

“…SPI/FVP coacervates exhibited solid-like properties and presented the strongest storage modulus at CNaCl = 50 mmol/L. The optimal pH, SPI/FVP ratio and NaCl concentration of complex coacervation were collected, and the coacervates demonstrated a valuable application potential to protect and deliver bioactives and food ingredients.…”
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Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi by Divyapriya Karthikeyan, Sanjit Kumar, NS Jayaprakash

“…Both compounds underwent toxicity prediction and ADMET analysis, showing favorable drug-like properties, with compound 1615 emerging as the most promising inhibitor due to its optimal electronic energy and minimal chemical potential. …”
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Inferior vena cava ultrasound in acute decompensated heart failure: design rationale of the CAVA‐ADHF‐DZHK10 trial by Alexander Jobs, Reinhard Vonthein, Inke R. König, Jane Schäfer, Matthias Nauck, Svenja Haag, Carlo Federico Fichera, Thomas Stiermaier, Jakob Ledwoch, Alisa Schneider, Miroslava Valentova, Stephan vonHaehling, Stefan Störk, Dirk Westermann, Tobias Lenz, Natalie Arnold, Frank Edelmann, Philipp Seppelt, Stephan Felix, Matthias Lutz, Felix Hedwig, Martin Borggrefe, Clemens Scherer, Steffen Desch, Holger Thiele

“…Abstract Aims Treating patients with acute decompensated heart failure (ADHF) presenting with volume overload is a common task. However, optimal guidance of decongesting therapy and treatment targets are not well defined. …”
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Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair by Penghui Wang, Zaifeng Chen, Ping Li, Abdullah Al Mamun, Shaoxia Ning, Jinjing Zhang, Chonghui Tang, Tianmiao Sun, Jian Xiao, Xiaojie Wei, Fenzan Wu

“…This intervention additionally preserves the integrity of the blood-spinal cord barrier, optimizes the spinal cord microenvironment, reduces glial scarring, promotes axonal regeneration, and enhances motor function recovery in SCI mice. …”
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Synergistic evolution of dual-precipitation and reverted austenite on mechanical properties in 2.4 GPa ultrahigh strength steel by Aijun Li, Yangxin Wang, Xinyu Jin, Jiaxin Liu, Chundong Hu, Han Dong

“…The synergistic interaction of these factors results in various mechanical properties of the steel after different heat treatments, providing new theoretical insights for optimizing the performance of ultrahigh strength steel. …”
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Pulsed Electromagnetic Field-Assisting Reduced Graphene Oxide-Incorporated Nanofibers for Osteogenic Differentiation of Human Dental Pulp Stem Cells by Juo Lee, Sungmin Lee, Iksong Byun, Myung Chul Lee, Jungsil Kim, Hoon Seonwoo

“…All groups demonstrated optimal cell adhesion and viability. RGO-NFs exhibited higher osteogenesis-related protein expression than PCL-only scaffolds, further enhanced by pulsed electromagnetic field (PEMF) application. …”
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Adsorption of Acid Yellow 36 and direct blue 86 dyes to Delonix regia biochar-sulphur by Ahmed Eleryan, Uyiosa Osagie Aigbe, Kingsley Eghonghon Ukhurebor, Mohamed A. Hassaan, Safaa Ragab, Otolorin Adelaja Osibote, Ismail Hossain, Ahmed El Nemr

“…Different characterization investigations using BJH, BET, FTIR, SEM, DSC, TGA, and EDX were utilized in the descriptions of the DRB-S biosorbent. The optimal pH for AY36 dye and DB86 dye adsorption to the DRB-S adsorvbent was at pH 1.5. …”
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Improving H2RG Performance in SPHEREx Brassboard Model by Chi H. Nguyen, Phillip Korngut, C. Darren Dowell, James Bock, Jill Burnham, Samuel Condon, Walter Cook, Grigory Heaton, Howard Hui, Branislav Kecman, Hiromasa Miyasaka, Kenneth Manatt, Hien T. Nguyen, Stephen Padin, Marco Viero

“…The instrument implements HAWAII-2RG (H2RG) detectors and custom-built Video8 electronics with multiple sampling features to optimize the H2RG noise performance, including nonsequential row reads, voltage monitoring, multiple visits to optically dark reference pixels, as well as onboard slope fitting and cosmic-ray removal. …”
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Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome by Bo Hai, Taeko Shigemoto-Kuroda, Qingguo Zhao, Ryang Hwa Lee, Fei Liu

“…To circumvent these issues, we derived MSCs from human iPSCs using an optimized protocol that can be easily scaled up to produce a huge amount of standardized MSCs. …”
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Modified ionosphere delay fitting model with atmosphere uncertainty grids for wide-area real-time positioning by Bobin Cui, Jungang Wang, Pan Li, Jiahuan Hu, Xiang Zuo, Longjiang Tang

“…To address this, we propose a novel ionospheric slant delay fitting model that adaptively selects the optimal reference path within coverage areas, describing differences between the reference propagation path and others through trigonometric functions. …”
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Preparation and Characterization of Electrospun Gelatin Nanofibers for Use as Nonaqueous Electrolyte in Electric Double-Layer Capacitor by Ditpon Kotatha, Masaharu Hirata, Mayuko Ogino, Satoshi Uchida, Masashi Ishikawa, Tetsuya Furuike, Hiroshi Tamura

“…After testing over a range of spinning times, GES electrolytes that were produced at 25 min (GES-25) had a suitable thickness for the assembly of EDLC with the optimized tensile properties and were used to fabricate EDLC test cells with EMImBF4. …”
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Factors associated with maternal mortality in Ica, Peru: A matched case-control study by Jorge Ybaseta-Medina, Marjorie Ybaseta-Soto, Olinda Oscco-Torres, Carmen Aquije-Paredes, Carmen Vera-Cáceres

“…Conclusions The identification of these factors highlights the urgent need to develop comprehensive strategies that optimize access to maternal health services and strengthen education on warning signs. …”
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