Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates by Jersley D. Chirawurah, Felix Ansah, Samuel Blankson, Bridget Adikah, Silas Nkansah Yeboah, Lucas Amenga-Etego, Gordon A. Awandare, Yaw Aniweh

“…This study aimed to assess the potency of gossypol against six laboratory strains and twenty-one clinical isolates of P. falciparum using optimized growth inhibition assays. Additionally, parasites with reduced susceptibility to gossypol were selected using the P. falciparum Dd2 background (Dd2_3.5 µM) and tested for cross-resistance to chloroquine, dihydroartemisinin (DHA), and three Malaria box compounds (MMV006087, MMV085203, and MMV008956). …”
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Robot Dynamic Path Planning Based on Prioritized Experience Replay and LSTM Network by Hongqi Li, Peisi Zhong, Li Liu, Xiao Wang, Mei Liu, Jie Yuan

“…First, Prioritized Experience Replay (PER) is utilized to prioritize experience data and optimize storage and sampling operations through the SumTree structure, rather than the conventional experience queue. …”
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Collision Milling of Oil Shale Ash as Constituent Pretreatment in Concrete 3D Printing by Lucija Hanžič, Mateja Štefančič, Katarina Šter, Vesna Zalar Serjun, Māris Šinka, Alise Sapata, Genādijs Šahmenko, Evaldas Šerelis, Baiba Migliniece, Lidija Korat Bensa

“…However, milling bottom ash may unlock its potential as an SCM, with the optimal milling frequency being ~100 Hz.…”
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Combining Passive Infrared and Microwave Satellite Observations to Investigate Cloud Microphysical Properties: A Review by Mariassunta Viggiano, Domenico Cimini, Maria Pia De Natale, Francesco Di Paola, Donatello Gallucci, Salvatore Larosa, Davide Marro, Saverio Teodosio Nilo, Filomena Romano

“…The use of synergy is often invoked to optimize the exploitation of the available information, but it is rarely implemented. …”
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Improved Reception of In-Body Signals by Means of a Wearable Multi-Antenna System by Thijs Castel, Patrick Van Torre, Emmeric Tanghe, Sam Agneessens, Günter Vermeeren, Wout Joseph, Hendrik Rogier

“…In this paper, we implement a reliable 3.5 Mbps wearable textile multi-antenna system suitable for integration into a jacket worn by a patient, and evaluate its potential to improve the In-to-Out Body wireless link reliability by means of spatial receive diversity in a standardized measurement setup. We derive the optimal distribution and the minimum number of on-body antennas required to ensure signal levels that are large enough for real-time wireless endoscopy-capsule applications, at varying positions and orientations of the implant in the human body.…”
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Experimental and Constitutive Model Study on Dynamic Mechanical Behavior of Metal Rubber under High-Speed Impact Loading by Youchun Zou, Chao Xiong, Junhui Yin, Kaibo Cui, Xiujie Zhu, Huiyong Deng, Shijun Song

“…The dynamic stress-strain curve of metal rubber is divided into three stages: elastic stage, plastic stage, and failure stage. The optimal energy absorption efficiency is greater than 0.5, and the maximum value can reach 0.9. …”
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Advances in the application of digital technology in orthodontic monitoring by WANG Qi, LUO Ting, LU Wei, ZHAO Tingting, HE Hong, HUA Fang

“…It aims to provide insights for researchers and clinicians to enhance the application of digital technology in orthodontics, improve treatment outcomes, and optimize patient experience. The digitization of diagnostic data and the visualization of dental models make chair-side follow-up monitoring more convenient, accurate, and efficient. …”
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Review of Spot Electricity Price Prediction Studies Based on Machine Learning Methods by JIA Heping, GUO Yuchen, MA Qianxin, YANG Zhenglin, ZHENG Yaxian, ZENG Dan, LIU Dunnan

“…In the context of developing a unified national electricity market， the development of a spot market helps promote the sharing and optimal allocation of electricity resources on a larger scale. …”
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Massive Subchorionic Thrombohematoma (Breus’ Mole) Associated with Fetal Growth Restriction, Oligohydramnios, and Intrauterine Fetal Death by Miyuki Miyagi, Tadatsugu Kinjo, Keiko Mekaru, Hayase Nitta, Hitoshi Masamoto, Yoichi Aoki

“…Magnetic resonance imaging can be optimal for diagnosing MST when ultrasound diagnosis is difficult.…”
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Dual functional hydrogel of osteoclastic-inhibition and osteogenic-stimulation for osteoporotic bone defect regeneration by Lei Yu, Wentao Wang, Chang Lv, Qian Chen, Peng Yang, Zhenrong Qi, Haomiao Yu, Ruiqi Cao, Wenhao Li, Yi Qin, Gaoran Ge, Peilai Liu, Lixin Zhu, Houyi Sun, Dechun Geng, Liang Zhang

“…This dual-action system synergistically regulates osteoblast and osteoclast activity, optimizing the pathological microenvironment of osteoporosis and facilitating the repair of osteoporotic bone defects. …”
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Detection of c-erbB-2 mRNAs Using Dig-Labelled Oligonucleotide Probe with in situ Hybridisation in Human Breast Carcinoma: Comparison with Immunohistochemical Results by Melek Öztürk, Sema Bolkent, Selma Yilmazer, Gültekin Kaner, Hilal Ünal

“…In ISH method digoxigenin-labelled oligoprobe was used for the detection of c-erbB-2 mRNAs. We determined optimal condition for the ISH procedure (e.g., probe concentration, digestion, post washing). c-erbB-2 protein overproduction was detected in 11/20 cases with IHC. …”
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Coping with Stress During the COVID-19 Pandemic: Resilience and Mental Health Among Latino Day Laborers by Sylvia A. Ayieko, John Atkinson, Anna Llamas, Maria E. Fernandez-Esquer

“…Resilience, the successful process of growth and adaptation in the face of adversity, stress, or trauma, is crucial for optimal well-being. During the COVID-19 pandemic, Latino day laborers (LDLs) faced multiple stressors, making them vulnerable to poor mental health outcomes. …”
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Data recommendation algorithm of network security event based on knowledge graph by Xianwei ZHU, Wei LIU, Zihao LIU, Zeyu GU

“…To address the difficulty faced by network security operation and maintenance personnel in timely and accurate identification of required data during network security event analysis, a recommendation algorithm based on a knowledge graph for network security events was proposed.The algorithm utilized the network threat framework ATT＆amp;CK to construct an ontology model and establish a network threat knowledge graph based on this model.It extracted relevant security data such as attack techniques, vulnerabilities, and defense measures into interconnected security knowledge within the knowledge graph.Entity data was extracted based on the knowledge graph, and entity vectors were obtained using the TransH algorithm.These entity vectors were then used to calculate data similarity between entities in network threat data.Disposal behaviors were extracted from literature on network security event handling and treated as network security data entities.A disposal behavior matrix was constructed, and the behavior matrix enabled the vector representation of network threat data.The similarity of network threat data entities was calculated based on disposal behaviors.Finally, the similarity between network threat data and threat data under network security event handling behavior was fused to generate a data recommendation list for network security events, which established correlations between network threat domains based on user behavior.Experimental results demonstrate that the algorithm performs optimally when the fusion weight α=7 and the recommended data volume K=5, achieving a recall rate of 62.37% and an accuracy rate of 68.23%.By incorporating disposition behavior similarity in addition to data similarity, the algorithm better represents factual disposition behavior.Compared to other algorithms, this algorithm exhibits significant advantages in recall rate and accuracy, particularly when the recommended data volume is less than 10.…”
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Controlled Signal Technique in VL‐NOMA Communication Under Interference‐Controlled Environment With Intelligent Reflecting Surfaces by C. E. Ngene, Prabhat Thakur, Ghanshyam Singh

“…We observed that the propagated signal improved the BER as per LOS, hence, the NLOS blocker reduced the signal's performance. Furthermore, we optimized the signals to investigate BER, LOS, and NLOS signal performance. …”
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Efficacious removal of mercury metal in food industry sewerage utilizing reduced graphene oxide adsorbent composited with magnetic nanoparticles by Adel Beig Babaei, Arash Dara, Hanieh Sadat Taheri

“…The findings indicated that optimal mercury adsorption occurred at pH 6, with a 100 s contact time, 25 °C, and 0.05 g of adsorbent. …”
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Bring dying at home: What facilitates and hinders home-based end-of-life care for people living with dementia?-A systematic review and meta-ethnography protocol. by Guo Yin, Divya Sivaramakrishnan, Leah Macaden

“…In addition, the results of this review will guide the development and improvement of home-based end-of-life care interventions for people living with dementia, and guide policymakers and practitioners to optimize relevant policies and services.…”
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Machine learning approach for predicting tramp elements in the basic oxygen furnace based on the compiled steel scrap mix by Michael Schäfer, Ulrike Faltings, Björn Glaser

“…Furthermore, an online model was implemented, accessible via a defined synchronous interface, which allows to optimize the use of different scrap types by predicting the chemical content at the end of the basic oxygen furnace process and simulating with new combinations of input material. …”
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Effect of pouring temperature on microstructure and durability of DD419 single crystal superalloy by ZHANG Hui, DING Qiang, LIU Jide

“…The finely dispersed γ′ phase enhances the alloy’s durability under all three test scenarios，with the alloy poured at 1500 ℃ exhibiting optimal durability. At intermediate temperature/high stress condition（1050℃/190 MPa），the γ′ phase is intersected by numerous dislocations, and dispersed γ′ phase may contribute to dislocation pile-ups. …”
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The Use of MSK Ultrasound with Quadriceps Muscle Injury by Robert C Manske, Michael Voight, Chris Wolfe, Phil Page

“…This information is invaluable in ensuring an optimal outcome for any quadriceps muscle and tendon injury. …”
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Impact of thermal variation on the naupliar development of the copepod Apocyclops spartinus (Ruber, 1968) (Copepoda: Cyclopidae), under controlled conditions by Pedro Pablo Alonso Sánchez-Dávila, Ruth Milagros Alejos-Cabrera, Wilmer Gaspar-Reyes, Jhon Dionicio-Acedo

“…In summary, A. spartinus nauplii exhibit potential as a live food source and it is recommended that targeted thermal treatments be employed to extend the time of optimal nauplii size and thereby enhance culture techniques of this species.…”
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