Rotationplasty with Vascular Reconstruction for Prosthetic Knee Joint Infection by Masahide Fujiki, Shimpei Miyamoto, Fumihiko Nakatani, Akira Kawai, Minoru Sakuraba

“…However, there has been little discussion regarding the optimal vascular management of rotationplasty after infection of prosthetic knee joints because rotationplasty is rarely performed for this indication. …”
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Unveiling the Emerging Role of Xanthine Oxidase in Acute Pancreatitis: Beyond Reactive Oxygen Species by Chenxia Han, Yaling Wu, Juan Rong, Qing Xia, Dan Du

“…There is no doubt that the ROS generated by irreversibly activated XO participates in the local pancreas and multiple organ failure during AP. However, the optimal timing and doses for therapeutic interventions targeting XO in animal studies and the clinic, as well as the additional molecular mechanisms through which XO contributes to disease onset and progression, including metabolic regulation, remain to be elucidated. …”
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Modulation of gut microbiota in targeted cancer therapy: insights on the EGFR/VEGF/KRAS pathways by Li Gong, Shixue Yang, Junli Huang, Yongsheng Li

“…By elucidating the connection between gut microbiota and the EGFR/VEGF/KRAS pathways, this review provides valuable insights for advancing targeted cancer therapy and optimizing treatment outcomes in clinical settings.…”
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C-28 linker length modulates the activity of second-generation HIV-1 maturation inhibitors by K. C. Yuvraj, Aradhana Singh, Sayantani Datta, Ritika Das, Pranjal Raj Saxena, Subash Chapagain, T. J. Nitz, Carl Wild, Ritu Gaur

“…Bevirimat (BVM), a first-in-class MI, displayed sub-optimal efficacy in clinical trials due to presence of SP1:V7A polymorphism in the Gag protein.This polymorphism is inherently present in HIV-1 subtype C and conferred resistance to BVM. …”
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Improvement of Surface Properties of Inconel718 by HVOF Coating with WC-Metal Powder and by Laser Heat Treatment of the Coating by Hui Gon Chun, Tong Yul Cho, Jae Hong Yoon, Gun Hwan Lee

“…High-velocity oxygen-fuel (HVOF) thermal spray coating with WC-metal powder was carried out by using optimal coating process on an Inconel718 surface for improvement of the surface properties, friction, wear, and corrosion resistance. …”
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Power Transformer Health Index Using Cost-Sensitive Learning to Consider the Impact of Misclassification by Junsoo Che, Gihun Park, Jeongsik Oh, Su-Han Pyo, Byeonghyeon An, Taesik Park

“…Within this asset management framework, a key metric that indicates the condition of facilities is the health index. To develop an optimal investment strategy for facility maintenance and management, a method for accurately calculating the health index is essential. …”
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Clinical Outcome of Third-Line Pazopanib in a Patient with Metastatic Renal Cell Carcinoma by Michela Roberto, Maria Bassanelli, Elsa Iannicelli, Silvana Giacinti, Chiara D’Antonio, Anna Maria Aschelter, Paolo Marchetti

“…In a context characterized by different emerging options, with no general consensus on the optimal treatment strategy, the use of pazopanib in pretreated patients could be a suitable choice.…”
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Characterization of evolution of reactive transport parameters during leaching process of sandstone uranium ore by combining porosity and lacunarity by Haiying Fu, Shuai Wang, Deming Tan, Guicheng He, Meng Lian, Zhonghua Zhu, Dexin Ding

“…This research provides valuable insights for optimizing the leaching process in sandstone uranium ore deposits.…”
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THE EFFECT OF SOIL NAILING INCLINATION FOR IMPROVEMENT OF GYPSUM SAND SOIL IN DIFFERENT SLOPES by Mustafa M. Abdalhusein, Yasir M. Al-Badran, Zuhair Abd Hacheem, Rusul H. Almahmodi, Mohammed S. Mahmood, Susan Mutar N. AlMihna

“…Based on these results, nine design tables were developed, providing empirical equations to determine optimal nailing lengths, inclination angles, and slope conditions for effective stabilisation. …”
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Design of a release-free piezo-optomechanical quantum transducer by Paul Burger, Joey Frey, Johan Kolvik, David Hambraeus, Raphaël Van Laer

“…It combines release-free lithium niobate electromechanical crystals with silicon optomechanical crystals on a sapphire substrate, optimizing thermal anchoring and microwave and mechanical coherence. …”
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Biosimilars in Focus: Evaluating Their Role Compared to Adalimumab in Clinical Practice by Dorota Waz, Michał Mazur, Jakub Szarłowicz, Zofia Goliszek, Karolina Łucja Sobek, Wiktoria Tabin-Barczak, Aldona Sokołowska, Klaudia Fikas, Kamil Chwaliszewski, Sebastian Samuła

“…Enhanced TDM and patient-centered strategies are essential for optimizing outcomes and maximizing their adoption in clinical practice. …”
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Simultaneous Determination of Benzene and Toluene in Pesticide Emulsifiable Concentrate by Headspace GC-MS by Lidong Cao, Hua Jiang, Jing Yang, Li Fan, Fengmin Li, Qiliang Huang

“…A nonpolar fused silica Rtx-5 capillary column (30 m×0.20 mm i.d. and 0.25 μm film thickness) with temperature programming was used. Under optimized headspace conditions, equilibration temperature of 120°C, equilibration time of 5 min, and sample size of 50 μL, the regression of the peak area ratios of benzene and toluene to IS on the concentrations of analytes fitted a linear relationship well at the concentration levels ranging from 3.2 g/L to 16.0 g/L. …”
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Comparison of the Heat Transfer Efficiency of Selected Counterflow Air-to-Air Heat Exchangers Under Unbalanced Flow Conditions by Kazimierz Kaminski, Pawel Znaczko, Ewa Kardas-Cinal, Norbert Chamier-Gliszczynski, Krzysztof Koscielny, Krzysztof Cur

“…These findings contribute to a better understanding of how real-world ventilation imbalances affect heat exchanger performance, offering insights to optimize energy efficiency in ventilation systems.…”
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Effect of Frying Combined with Roasting on the Quality of Roasted Green Tea by ZHANG Rongxiang, DU Yaru, ZHANG De, DONG Zhijie, NI Dejiang, ZHENG Shibing, YU Zhi

“…The roller frying parameters were optimized using principal component analysis (PCA). …”
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Coordinated allocation of distributed generation, soft open points and energy storage systems in unbalanced distribution networks considering flexibility deficiency risk by Jie Wang, Xiaochao Fan, Lijun Xu, Ruijing Shi, Weiqing Wang

“…Optimizing the location and capacity of flexible resources is critical. …”
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EFFECT OF PLATELET RICH FIBRIN AND MESENCHYMAL STEM CELL ON MYOBLAST AND FIBROBLASTS RATIO IN RABBIT MUSCLE DEFECT by Dwikora Novembri Utomo, Mohammad Zaim Chilmi, Angga Fiandana

“…This is due to slow healing process and outcome has not been optimal because it produces scar tissue. Purpose: To evaluate effect of platelet rich fibrin and allogenic mesenchymal stem cell on muscle regeneration through comparation of myoblast and fibroblast ratio. …”
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Career Perspectives for Pediatric Orthopaedic Trainees and Early Practitioners: A Panel Discussion by Jeffrey B. Peck, MD, William Cutchen, MD, Lee Haruno, MPH, Dustin Greenhill, MD, Karen Bovid, MD, Brandon Ramo, MD

“…Key Concepts: (1) When selecting a fellowship, it is valuable to understand one's learning style and to consider family needs. (2) After discovering what positions may be available, match each potential position's professional and personal opportunities with your needs. (3) Your initial practice will evolve to your ideal professional endpoint over years of effort and development. (4) The optimal work-life relationship is possible with good communication with your partner/family and with a good team of supporting healthcare staff around you. (5) Regular attendance at the POSNA annual meeting and involvement in committee work can be a resource and provide tremendous professional satisfaction.…”
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Modeling of the Radiation Doses during Dismantling of RBMK-1500 Reactor Pressurized Tanks from Emergency Core Cooling System by A. Simonis, P. Poskas, A. Sirvydas, D. Grigaliuniene

“…In order to select the optimal personnel radiation safety, the modeling has been performed by the means of computer code “VISIPLAN 3D ALARA Planning tool” developed by SCK CEN (Belgium). …”
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Image Quality Inprovement for Small Vessel in Diabetic Foot Arteriography Using Dual-energy Computed Tomography by Yikai ZANG, Jing LI, Xiuliang LU, Cheng YAN

“…Methods: A total of 30 patients with diabetes were enrolled prospectively between January and November 2022 in the radiology department of our hospital, where DECT was acquired immediately after the CT angiography (routine CTA group) of the lower extremity.The optimal virtual monochromatic images (DECT group) were derived from the DECT data. …”
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Effectiveness of ethanol extract of Morinda citrifolia L. as an anti-inflammatory: A preclinical study by Mega Hayati, Ali Napiah Nasution, Ermi Girsang, Adek Amansyah, Fioni

“…The aims of this research to evaluate the anti-inflammatory effects and optimal dosing of ethanol extract of noni fruit in reducing paw edema and improving histopathological conditions in male rats induced with Complete Freund's Adjuvant (CFA). …”
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