A multifunctional mesoporous silica drug delivery nanosystem that ameliorates tumor hypoxia and increases radiotherapy efficacy by Yanhong Chu, LiFeng Wang, Yaohua Ke, Xiaoyu Feng, Wenmei Rao, Wei Ren, Kai Xin, Yan Wang, Lixia Yu, Baorui Liu, Qin Liu

“…Abstract Radiotherapy (RT) is a widely used treatment with strong therapeutic effects, but overcoming challenges related to hypoxia-induced tumor resistance and ineffective antitumor immune responses is crucial for optimal outcomes. In this study, we developed a versatile nanosystem using mesoporous silica nanoparticles (MSNs), R837, and a small quantity of manganese peroxide (Mn/ZnO2). …”
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Integrated Spectral Sensitivity as Physics-Based Figure of Merit for Spectral Transducers in Optical Sensing by Felix L. McCluskey, Anne van Klinken, Andrea Fiore

“…In reality, however, different transducers achieve optimal performance with different types of readout. …”
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Deep learning in defects detection of PV modules: A review by Katleho Masita, Ali Hasan, Thokozani Shongwe, Hasan Abu Hilal

“…Identifying defects in photovoltaic (PV) modules is essential for ensuring optimal performance and prolonging their operational lifespan. …”
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Cytochrome P450 monooxygenase-mediated eicosanoid pathway: A potential mechanistic linkage between dietary fatty acid consumption and colon cancer risk by Weicang Wang, Jianan Zhang, Guodong Zhang

“…Animal experiments showed that excessive LA intake increased azoxymethane-induced colon tumorigenesis, however, the impact of excessive LA on colon cancer in human is not conclusive, making it difficult to make dietary recommendations for optimal intake of LA. Understanding the molecular mechanisms of LA on colon tumorigenesis could help to clarify its health effect, and facilitate development of mechanism-based strategies for preventing colon cancer. …”
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A Gradual Approach for Multimodel Journey Planning: A Case Study in Izmir, Turkey by Feriştah Dalkılıç, Yunus Doğan, Derya Birant, Recep Alp Kut, Reyat Yılmaz

“…The algorithm utilizes the techniques of efficient algorithms including round based public transit optimized router, transit node routing, and contraction hierarchies on transportation graph. …”
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Knowledge, Awareness, and Attitudes about Research Ethics among Dental Faculty in the Middle East: A Pilot Study by Hadir F. El-Dessouky, Amr M. Abdel-Aziz, Chadi Ibrahim, Malini Moni, Reham Abul Fadl, Henry Silverman

“…Finally, some faculty held attitudes regarding certain research ethics practices that were not optimal. Conclusions. We conclude that among the dental faculties participating in our study, there is broad-based acceptance of RECs and training in research ethics, while there are knowledge gaps in research ethics. …”
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Effects of Mulberry Pomace Addition and Transglutaminase Treatment on the Quality of Pasta Enriched with Antioxidants and Dietary Fiber by Thi Minh Ngoc Ta, Chi Hieu Hoang, Thao Mi Nguyen, Thi Thu Tra Tran, Nu Minh Nguyet Ton, Le Van Viet Man

“…The cooking loss increased with the substitution level of mulberry pomace while the optimal cooking time, swelling index and water absorption index decreased. …”
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Design Considerations for Sub-1-V 1T1C FeRAM Memory Circuits by Mohammad Adnaan, Sou-Chi Chang, Hai Li, Yu-Ching Liao, Ian A. Young, Azad Naeemi

“…We identify the critical aspects of the ferroelectric memory array performance, such as the effect of plateline driver and bitline capacitances, and provide recommendations to further optimize the performance of such low operating voltage ferroelectric memory circuits.…”
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Domain Alignment Dynamic Spectral and Spatial Feature Fusion for Hyperspectral Change Detection by Xuexiang Qin, Yuxiang Zhang, Yanni Dong

“…First, DADSSFF uses the main network to optimize the alignment of the mean (first-order statistics) and correlation (variance, second-order statistics) of the bitemporal images, coordinating features across both levels to alleviate the issue of inconsistent feature distribution. …”
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Study on load reduction and vibration control strategies for semi-submersible offshore wind turbines by Dongxiao Bai, Bing Wang, Yinsheng Li, Wancheng Wang

“…Abstract Independent pitch control (IPC) is a crucial technology for enhancing the performance of wind turbines, optimizing the power output, and reducing the loads by managing each blade. …”
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Distribution changes of Ormosia microphylla under different climatic scenarios by Pan Huang, Yaqin Xiao, Yurong Sun, Huihua Huang, Zhiwei Gong, Yingfang Zhu

“…Here distribution data of O. microphylla and environmental data with an optimized MaxEnt maximum entropy model were used to predict potentially suitable areas under current and future climate scenarios. …”
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Review of Progress on Printing Techniques Towards Commercialization of Perovskite Solar Cells by Mai Ali Alharbi, Shubhranshu Bhandari, Tapas Mallick

“…Future research should focus on optimizing printing techniques to improve the stability and scalability of PSCs. …”
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Influence of interlayer dwell time on microstructure and mechanical properties additively manufactured 316L stainless steel by laser directed energy deposition by Zhaoqiang Chen, Ziyu Zhang, Yuying Yang, Guangchun Xiao, Mingdong Yi, Tingting Zhou, Chonghai Xu

“…These findings underscore the importance of optimizing the laser interlayer residence time to improve the overall performance of 316L stainless steel parts.…”
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Temporal-Spatial Traffic Flow Prediction Model Based on Prompt Learning by Siteng Cai, Gang Liu, Jing He, Yulun Du, Zhichao Si, Yunhao Jiang

“…The model presents efficient learning performance that reaches optimal state in a short period of time, reduces the impact of distribution shifts, and can be adapted to spatiotemporal traffic flow data under varying spatiotemporal contexts.…”
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Mesenchymal Stem Cells in Renal Fibrosis: The Flame of Cytotherapy by Quan Zhuang, Ruoyu Ma, Yanshuang Yin, Tianhao Lan, Meng Yu, Yingzi Ming

“…Yet, the current method of treating renal fibrosis is fairly limited, including angiotensin-converting enzyme inhibition, angiotensin receptor blockade, optimal blood pressure control, and sodium bicarbonate for metabolic acidosis. …”
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Evaluation of Tumor Viability for Primary and Bone Metastases in Metastatic Castration-Resistant Prostate Cancer Using Whole-Body Magnetic Resonance Imaging by Hiromichi Iwamura, Yasuhiro Kaiho, Jun Ito, Go Anan, Nozomi Satani, Tomonori Matsuura, Ryo Tamura, Kazuhiro Murakami, Kaneki Koyama, Makoto Sato

“…The use of WB-MRI to detect viable disease lesions may enable us to design optimal treatment strategies for patients with metastatic castration-resistant prostate cancer.…”
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Electromigration Techniques in the Analysis of Selected Cosmetic Ingredients: A Review by Joanna Kończyk, Magdalena Myga-Nowak, Rajmund Michalski, Katarzyna Janoszka

“…A well-chosen technique and optimized analytical conditions ensure high sensitivity, repeatability, and resolution, achieving detection limits that meet legal requirements. …”
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Achieving simultaneous improvement of bendability and deep drawability of Al–Mg–Si alloy via intermediate annealing by Xin Zhan, Jianguo Tang, Xiaofen Tan, Mingan Chen, Wenhui Liu, Lingyong Cao, Lingying Ye, Xini Yuan, Gaohui Cao, Yong Zhang, Xiyan Hu, Xiaoguang Zhao

“…These results suggest that achieving both high bendability and deep drawability in Al–Mg–Si alloy is feasible by optimizing IA temperature. This study provides an experimental basis for the possibility of broader applications of Al–Mg–Si alloys in the automotive industry.…”
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Muscle Satellite Cells: Exploring the Basic Biology to Rule Them by Camila F. Almeida, Stephanie A. Fernandes, Antonio F. Ribeiro Junior, Oswaldo Keith Okamoto, Mariz Vainzof

“…Every phase of satellite cell activity is highly regulated and orchestrated by many molecules and signaling pathways; the elucidation of players and mechanisms involved in satellite cell biology is of extreme importance, being the first step to expose the crucial points that could be modulated to extract the optimal response from these cells in therapeutic strategies. …”
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Yttrium-doped NiMo-MoO2 heterostructure electrocatalysts for hydrogen production from alkaline seawater by Shujie Liu, Zhiguo Zhang, Kamran Dastafkan, Yan Shen, Chuan Zhao, Mingkui Wang

“…Introducing yttrium into the NiMo/MoO2 heterostructure induces lattice expansion and optimizes the d-band center of NiMo alloy component, enhancing water dissociation and H* desorption. …”
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