Oligomerization of Fischer-Tropsch Olefins by Radical Initiation Method for Synthesizing Poly Olefin Base Oils by Yash Vijay Kataria, Vera P. Kashparova, Victor А. Klushin, Olga P. Papeta, Roman E. Yakovenko, Ivan N. Zubkov

“…It was determined that when the oligomerization is carried out in polar solvents such as acetone and dichloromethane the yield of product increases by ~2.1 and ~1.7 times, respectively, while at the same time adding a non-polar solvent such as tetrachloromethane to the reaction mixture decreases the product yield by ~2.0 times. The optimal technological parameters for carrying out oligomerization process of synthetic gasoline and diesel fractions were determined: where azobisisobutyronitrile, content 0.5 wt.%., is used as an initiator, acetone as solvent, with reaction temperature of 200 °C, and duration of 12 hrs. under inert atmosphere. …”
Get full text

Neoadjuvant Immunotherapy and De-escalation of Surgery in Locally Advanced Breast Implant-associated Anaplastic Large Cell Lymphoma by Marzia Salgarello, Jaroslaw Krupa, Rebecca Allchin, Simon Pilgrim, Fiona Miall, Arianna Di Napoli, Maurizio Martelli, Giulio Tarantino

“…Due to the complex nature of this disease, a multidisciplinary approach is necessary for optimal management, particularly in locally advanced disease or inoperable patients. …”
Get full text

Stapled End-To-Side Ileocolic Anastomosis in Crohn’s Disease: Old Dog, Reliable Tricks? A Retrospective Two-Center Cohort Study by Volkan Doğru, MD, Jean H. Ashburn, MD, Umut Akova, BS, Alton G. Sutter, MD, Eren Esen, MD, Emily M. Gardner, MD, Andre da Luz Moreira, MD, Arman Erkan, MD, John Kirat, MD, Michael J. Grieco, MD, Feza H. Remzi, MD

“…Yet, despite heterogeneous data from different anastomotic configurations, there remains no clear guidance as to the optimal technique. Methods:. In a retrospective cohort design, patients undergoing ileocolic anastomosis in the setting of Crohn’s disease between 2016 and 2021 at two institutions were identified. …”
Get full text

Design of a novel Cu-Cr-X alloy with high strength and high electrical conductivity based on mechanical learning by Yunqing Zhu, Yicheng Cao, Lijun Peng, Qian Yu, Zhen Yang, Zengde Li, Junsheng Wu, Haofeng Xie

“…The Cu-Cr-Zr-Mg-Ti alloy with superior properties was optimally designed by genetic algorithm from the massive solutions, which the experimental tensile strength and conductivity reached 668 MPa and 71.5 %IACS, respectively. …”
Get full text

Establishment of a prognostic signature and immune infiltration characteristics for uterine corpus endometrial carcinoma based on a disulfidptosis/ferroptosis-associated signature by Yong Huang, Huibin Li, Zhifu Wei, Wanshan He, Bin Chen, Shuang Cheng, Zhifang Zhao, Lv Deng, Lv Deng, Xiaohua Chen, Yu Lin, Yu Lin, Xiaoshan Hong, Xiaoshan Hong

“…Finally, we validated the prognostic gene expression profile in clinical samples.ResultsWe identified five optimal DFRGs that were differentially expressed and associated with the prognosis of uterine corpus endometrial carcinoma (UCEC). …”
Get full text

Recent progress in triboelectric platforms: engineering materials to industrial applications from the perspective of manufacturing by Yoonsang Ra, Minjun Song, Donghan Lee, Sunmin Jang, Yu-seop Kim, Joonmin Chae, Sumin Cho, Dongik Kam, Donghyun Lee, Gibeom Lee, Younghoon Lee, Dongwhi Choi

“…Given its unique strength, which includes a diverse material selection and a simple working mechanism, the triboelectric platform can use a variety of manufacturing technologies and the process can be optimized as needed. Numerous research groups have clearly demonstrated the triboelectric platform’s advantages. …”
Get full text

Prospective Evaluation of Unprocessed Core Needle Biopsy DNA and RNA Yield from Lung, Liver, and Kidney Tumors: Implications for Cancer Genomics by Mikhail T. Silk, Nina Mikkilineni, Tarik C. Silk, Emily C. Zabor, Irina Ostrovnaya, Ari A. Hakimi, James J. Hsieh, Etay Ziv, Natasha Rekhtman, Stephen B. Solomon, Jeremy C. Durack

“…Since non-formalin-fixed DNA is advantageous for molecular studies, workflows that optimize core needle biopsy yield for molecular characterization should be explored.…”
Get full text

Polymorphic variants of the <i>hOGG1, APEX1, XPD, SOD2</i>, and <i>CAT</i> genes involved in DNA repair processes and antioxidant defense and their association with breast cancer r... by А. А. Timofeeva, V. I. Minina, A. V. Torgunakova, О. А. Soboleva, R. А. Тitov, Ya. А. Zakharova, M. L. Bakanova, А. N. Glushkov

“…Using MDR analysis, the most optimal statistically significant 3-locus model of gene-gene interactions in the development of luminal B Her2-negative subtype breast cancer was found. …”
Get full text

Machine learning model and nomogram to predict the risk of heart failure hospitalization in peritoneal dialysis patients by Liping Xu, Fang Cao, Lian Wang, Weihua Liu, Meizhu Gao, Li Zhang, Fuyuan Hong, Miao Lin

“…The performance was validated using fivefold cross-validation. The optimal ML algorithm was used to construct the models to predictive the risk of the HF and all-cause mortality. …”
Get full text

Multiple Dimensions Define Thresholds for Population Resilience of the Eastern Oyster, Crassostrea virginica by Megan K. La Peyre, Hongqing Wang, Shaye E. Sable, Wei Wu, Bin Li, Devin Comba, Carlos Perez, Melanie Bates, Lauren M. Swam

“…These conditions are defined by a minimum, maximum, and optimal ranges of single and combined factors. Forays into environmental conditions outside the minimum or maximum tolerance of a species (i.e., thresholds) are predicted to have large effects on a species' population and may help predict population resilience in the face of changing conditions. …”
Get full text

Recommendations of the Russian Gastroenterological Association on Clinical Use of High-Resolution Manometry in Diagnosis of Esophageal Disorders by V. T. Ivashkin, I. V. Mayev, A. S. Trukhmanov, O. A. Storonova, S. A. Abdulkhakov, D. N. Andreev, D. S. Bordin, E. R. Valitova, I. L. Klyaritskaya, V. V. Krivoy, Yu. A. Kucheryavyi, T. L. Lapina, S. V. Morozov, O. A. Sablin, E. V. Semenikhina, Yu. P. Uspenskiy, A. A. Sheptulin

“…It enables a medical professional to obtain evidence that may critically affect the choice of optimal patient care strategy and effective treatment. …”
Get full text

Can Caffeine Be an Effective Ergogenic Aid in Combat Sports? A Comprehensive Review by Marcin Komorowski, Michał Janiszewski, Aleksandra Pelczarska, Rafal Kaczorowski, Tomasz Forenc, Jaromir Hunia, Julia Górny, Jonasz Jurek, Alicja Kapciak

“…Aim of Study: The primary aim of this study is to analyze the effects of caffeine on performance in combat sports, considering various factors such as optimal dosage, timing, and the impact of habitual caffeine consumption. …”
Get full text

Can “LITE” Procedure Combined With a Short Course Antibiotic Treatment Be Effective in Treating the Chronic PJI?—A Prospective Randomized Controlled Trial by Yang Chen, Haiqi Ding, Qijin Wang, Zida Huang, Chaofan Zhang, Wenbo Li, Yansheng Lin, Yufeng Guo, Xinyu Fang, Wenming Zhang

“…ABSTRACT Objective The prevailing treatment for chronic periprosthetic joint infection (PJI) is a two‐stage exchange, yet the optimal duration of antibiotic therapy following this procedure remains a topic of debate. …”
Get full text

An AI recognition method for children's clinical operative pain by skin potential (SP) signal by Mingxuan Huang, Cangcang Fu, Linbo Chui, Jiadong He, Xiaozhi Wang, Jikui Luo, Bin Wu, Yonggang Chen, Shaohua Hu, Jihua Zhu, Yubo Li

“…Then, we applied wavelet transform (WT) to capture the time-frequency characteristics of the signals and extract energy features and created a feature set comprising 30 features and selected 10 most relevant ones using the “SelectKBest” function.We compared six algorithms, optimized their parameters, and evaluated the stability and fitting performance of each algorithm. …”
Get full text

Development, in vitro and ex vivo characterization of lamotrigine-loaded bovine serum albumin nanoparticles using QbD approach by Maryana Salamah, Bence Sipos, Zsuzsanna Schelz, István Zupkó, Ágnes Kiricsi, Ágnes Szalenkó-Tőkés, László Rovó, Gábor Katona, György Tibor Balogh, Ildikó Csóka

“…The present study aimed to prepare and optimize lamotrigine-loaded bovine serum albumin nanoparticles (LAM-NP) using the Quality by Design (QbD) approach and to investigate both the in vitro and ex vivo effects of different cross-linking agents glutaraldehyde (GLUT), glucose (GLUC) and 1-(3-dimethylaminutesopropyl)-3-ethylcarbodiimide hydrochloride (EDC) on intranasal applicability. …”
Get full text

Epidemiology and Treatment Patterns of Fistulizing Crohn’s Disease in a Large, Real-World Australasian Cohort by Jack McNamara, William Wilson, Joseph L. Pipicella, Simon Ghaly, Jakob Begun, Ian C. Lawrance, Richard Gearry, Jane M. Andrews, Susan J. Connor

“…Conclusion: People with fCD used more health-care resources, making this an important area for further research into care gaps to improve outcomes and optimal treatment approaches.…”
Get full text

Adaptation of an additively manufactured reactor concept for catalytic methanation with in-situ tar co-reforming of biogenic syngas by Jakob Müller, Alexander Feldner, Simon Markthaler, Peter Treiber, Jürgen Karl

“…ADDmeth3.1 uses a dedicated internal channel structure that serves as a counter-current heat exchanger for the feed gas, whereas ADDmeth3.2 is optimized to fill the triangular footprint of a scalable reactor module as best as possible. …”
Get full text

Technical Proficiency Analysis in Table Tennis: A Comparative Study Between Advanced and Intermediate Players by Benny Aprial, Denny Setyawan, George Danut Mocanu, Candra Brema Tarigan, Ghulam Mustafa, John Michael D. Aquino, Bilal Azmi Sarıtaş

“…Biomechanical analysis showed advanced players maintained more optimal arm angles (110.5° vs 95.8°) and faster bat swing speeds (17.8 m/s vs 12.4 m/s). …”
Get full text

Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis by Yajuan Li, Huilan Wei, Xiaoting Dai, Lijing Zhang, Liangjie Liu, Xiaomei Chen, Tian Liu, Ya Shu, Yaxin Yang, Shi Wang, Zhenmin Bao, Lingling Zhang

“…The dwarf surfclam (Mulinia lateralis) is considered an optimal bivalve model due to its relatively short generation time and ease of breeding in laboratory settings. …”
Get full text

Diversity of frontier processes in Amazonian subnational jurisdictions: Frontier metrics reveal major patterns of human–nature interactions by Guido Briceño, Julie Betbeder, Agnès Bégué, Guillaume Cornu, David Katz-Asprilla, Marie-Gabrielle Piketty, Solen Le Clech, Vinicius Silgueiro, Hélène Dessard, Lilian Blanc

“…The weighted k-means approach was linked to nine metrics covering the period 1990–2021 in three subnational jurisdictions of the Brazilian and Colombian Amazon: 1. baseline forest, 2. percentage forest loss, 3. remaining forest, 4. speed of forest loss, 5. active deforestation, 6. percentage forest degradation, 7. speed of forest degradation, 8. active degradation, and 9. percentage regrowth. Four optimal archetypes were chosen using k-means classification: a. consolidated frontier, b. vulnerable frontier, c. past gradual frontier and d. rampant frontier. …”
Get full text