U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults by Chuanwei Zhao, Xiaochun Zhang, Xu Zhang, Bo Zhao, Yane Yang, Mu Lin, Wenli Qiao, Zeyao Hu, Haijie Yang

“…Further longitudinal studies are required to validate these findings and determine optimal lipid management strategies for osteoporosis prevention.…”
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Carbon Budget Assessment and Influencing Factors for Forest Enterprises in the Key State-Owned Forest Area of the Greater Khingan Range, Northeast China by Hui Wang, Wenshu Lin, Jinzhuo Wu, Zhaoping Luan

“…Influencing factors are identified through correlation analysis and the optimal parameter geographical detector (OPGD), while their spatial-temporal variations and causal relationships are analyzed using the geographical and temporal weighted regression model (GTWR) and structural equation modeling (SEM). …”
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A Rapid and Nondestructive Quality Detection Approach for Yongchuan Xiuya Tea Based on NIRS and siPLS-ANN Method by Ying Zhang, Jie Wang, Xiuhong Wu, Rui Chang, Hongyu Luo, Juan Yang, Quan Wu, Ze Xu, Yingfu Zhong

“…Through preprocessing the spectral data and employing the synergy interval partial least squares (siPLS) method to identify characteristic spectral regions, principal component analysis (PCA) is applied, followed by the development of a Jordan–Elman artificial neural network prediction model (ANN) for tea quality assessment. The optimal spectral preprocessing approach identified in this study is a combination of multiplicative scatter correction and second derivative processing. …”
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Factors influencing breast milk donation to a human milk bank in Iran: implications for policymakers and planners by Leila Doshmangir, Maryam Naghshi, Kamal Gholipour, Ayat Ahmadi, Hosein Azizi, Vladimir Sergeevich Gordeev

“…Abstract Background The World Health Organization (WHO) actively promotes breastfeeding as the optimal source of nourishment for infants and young children. …”
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Use of Multiple Doses of Intravenous Infusion of Umbilical Cord-Mesenchymal Stem Cells for the Treatment of Adult Patients with Severe COVID-19-Related Acute Respiratory Distress S... by Po-Ren Hsueh, Sung-Jung Ho, Po-Chuen Hsieh, I-Min Liu, Shio-Shin Jean

“…In Taiwan, few adult patients with severe COVID-19-induced ARDS receiving compassionate adjuvant treatment consisting of either a single dose (1–10 × 106 cells/kg body weight (kg BW)) or three doses (5 × 106 cells/kg BW in each dose) of IVF-UC-MSCs had good outcomes. However, the optimal dosage and rounds of IVF-UC-MSCs administration for the treatment of severe COVID-19 patients with ARDS are undetermined. …”
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Deep-TEMNet: A Hybrid U-Net–2D LSTM Network for Efficient and Accurate 2.5D Transient Electromagnetic Forward Modeling by Zhijie Qu, Yuan Gao, Kang Xing, Xiaojuan Zhang

“…The U-Net component enables high-resolution spatial feature extraction, while the 2D LSTM module enhances temporal modeling by processing spatial sequences in two dimensions, thereby optimizing the representation of electromagnetic field dynamics over time. …”
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Effect of Biofloc Culture on the Daily Rhythmicity of the Activity and Expression of Digestive Enzymes in Tilapia, Oreochromis niloticus by María del Carmen Monroy-Dosta, Daniel Becerril-Cortés, Juan Pablo Lazo, Arturo Mena-López, Pilar Negrete-Redondo, Eliasid Nogueda-Torres, Carmen Navarro-Guillén, José Antonio Mata-Sotres

“…These findings should be considered when establishing new optimized culture protocols.…”
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The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development by Pralay Mukhopadhyay, Hesham A. Abdullah, Joanna B. Opalinska, Prani Paka, Eric Richards, Katja Weisel, Suzanne Trudel, Maria-Victoria Mateos, Meletios Athanasios Dimopoulos, Sagar Lonial

“…Protocol amendments reflecting DREAMM-3 learnings could also be implemented prospectively on the combinations trials to optimize the follow-up duration and mitigate risk. …”
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Efficacy of high-dose steroids versus low-dose steroids in the treatment of immune checkpoint inhibitor-associated myocarditis: a case series and systematic review by Xiuyue Man, Hong Wang, Chen Chen, Xiaofeng Cong, Lemeng Sun, Xueru Sun, Chen Chen, Jing Zhang, Lei Yang

“…This intervention rapidly lowers myocardial injury biomarkers (cTnI/T, CK, NT-proBNP) while minimizing the risk of biomarker rebound, thus optimizing clinical management. Notably, it significantly reduces the incidence of major adverse cardiovascular events (MACE), thereby enhancing patient prognosis. …”
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An X-Linked Hyper-IgM Patient Followed Successfully for 23 Years without Hematopoietic Stem Cell Transplantation by Necil Kutukculer, Neslihan Edeer Karaca, Guzide Aksu, Ayca Aykut, Erhan Pariltay, Ozgur Cogulu

“…When caring for patients with life-limiting diseases, improving survival and optimizing quality of life are the primary goals. For patients with X-linked hyper-IgM syndrome (XHIGM), the treatment modality has to be decided for a particular patient regarding hematopoietic stem cell transplantation or intravenous immunoglobulin replacement therapy with P. jiroveci prophylaxis. …”
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The Life Mission Theory III. Theory of Talent by Soren Ventegodt, Niels Jorgen Andersen, Joav Merrick

“…Thus, self-actualisation is a result of a person fully expressing and realizing his core talent.The theory of talent states that a core talent can be expressed optimally when a human being takes possession of a three-dimensional space with the axis of purpose, power and gender, as we have a threefold need: 1-Acknowledging our core talent (our purpose of life) and intending it 2-Understanding our potential powers and manifesting them 3-Accepting our human form including our sex and expressing itThe first dimension is spiritual, the next dimension is mental, emotional and physical, and the third dimension is bodily and sexual. …”
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Removal of Ammonium from Aqueous Solutions Using Zeolite Synthesized from Electrolytic Manganese Residue by Changxin Li, Yuan Yu, Qingwu Zhang, Hong Zhong, Shuai Wang

“…Maximum ammonium uptake capacity was achieved at pH value 8.0, EMRZ dosage 0.2 g/100 mL, contact time 100 min, initial ammonium concentration 200 mg/L, and temperature 35°C. Under optimized conditions, ammonium uptake capacity onto EMRZ was up to 27.89 mg/g. …”
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Developing a Predictive Tool for Hospital Discharge Disposition of Patients Poststroke with 30-Day Readmission Validation by Jin Cho, Krystal Place, Rebecca Salstrand, Monireh Rahmat, Misagh Mansouri, Nancy Fell, Mina Sartipi

“…Early prediction of discharge destination can optimize poststroke care and improve outcomes. Previous attempts to predict discharge disposition outcome after stroke have limited clinical validations. …”
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Effects of different doses of skt-b vibrio probiotic bacteria addition on survival and growth rate of tiger shrimp (Penaeus monodon) larva by . Widanarni, M.A. Lidaenni, Dinamella Wahjuningrum

“…Hasil penelitian menunjukkan bahwa dosis optimal untuk larva udang windu adalah 104 CFU/ml dengan nilai kelangsungan hidup 94,67%. …”
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Health-related quality of life after prosthodontic rehabilitation in patients with COVID-19-associated mucormycosis: A systematic review by Gunjan Chouksey, Rupali Choure, Kritika Singhal

“…Health-related quality of life (HRQOL) measures an individual’s ability to function optimally in various aspects of life and their subjective sense of well-being across the physical, mental, and social dimensions of health. …”
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Biochemistry of the Thrombin-Like TLBpic and Its Purification from Bothrops pictus “Jergon de la Costa” (Reptilia: Viperidae) by Victor Ludgardo Álvarez Tohalino, Hugo Guillermo Jiménez Pacheco, Juan Raúl Jesús Zumaran Farfán, Pavel Kewin Delgado Sarmiento, Paulino Rodolfo Zegarra Panca

“…The main characteristic of our protocol is the speed, and the high recovery of the fraction with optimal terms gave result of evidence in the SDS-PAGE gel. …”
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Association of bud and anther morphology with developmental stages of the male gametophyte of melon (Cucumis melo L.) by M. L. Nguyen, T.N.B.T. Huyen, D. M. Trinh, A. V. Voronina

“…To successfully apply this technique in a new culture, one has to optimize many of its elements: f irst, f ind the biological markers for selecting the f lower buds containing the microspores of certain development stages. …”
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Isolation, characterization and liposome-loaded encapsulation of a novel virulent Salmonella phage vB-SeS-01 by Yuhang Luo, Jacques Mahillon, Lin Sun, Ziqiong You, Xiaomin Hu

“…Among the nine vB-SeS-01 liposome-carrying formulations, the one encapsulated with PC:Chol:T80:SA = 9:1:2:0.5 without sonication displayed the optimal features. This formulation carried up to 1011 PFU/mL, with an encapsulation rate of 80%, an average size of 172.8 nm, and a polydispersity index (PDI) of 0.087. …”
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Health Benefits in a Cohort of Children 6 Months After Tonsil Surgery in Relation to the Perioperative Period: An Observational Prospective Cohort Study by Lundeberg Stefan, Elisabeth Ericsson

“…Pain management needs to be optimized to improve recovery.…”
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Sustainable human resource management practices in organizational performance: The mediating impacts of knowledge management and work engagement by Shatha Abu-Mahfouz, Mutia Sobihah Abd Halim, Ayu Suriawaty Bahkia, Noryati Alias, Ph.D. in Management, Abdul Malek Tambi

“…IMPLICATIONS: Overall, employee cooperation proved essential to optimize organizational performance, specifically during their engagement in sustainable HRM practices and knowledge management. …”
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