Antioxidant, Physiochemical, and Sensory Properties of Functional Marshmallow Produced from Honey, Strawberry Concentrates, and Hibiscus Extract by Maher M. Al-Dabbas, Etaf G. Abu Samaan, Sehar Iqbal, Hani J. Hamad, Rawan Al-Jaloudi, Mohammad Shahein, Bha’a Aldin Al-Nawasrah, Abdalrahman Al-Zabt, Doa`a Al-Refaie, Nisreen Shehadeh, Mahmoud Abughoush

“…This study, therefore, aimed to develop optimal formulations for functional marshmallow candy using honey, aqueous hibiscus extract, cow’s milk, and strawberry concentrates with partial replacement of table sugar and glucose syrup. …”
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Pharmacokinetics and pharmacodynamics of ciprofol after continuous infusion in elderly patients by Xiaowen Guo, Yang Qiao, Sijie Yin, Fengqin Luo, Lingmei Yi, Jiajia Chen, Man Lu

“…For elderly patients undergoing gastrointestinal tumor surgery, an optimal maintenance dose of 0.8 mg/kg/h is recommended. …”
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Analysis of the Spatial Pattern of Military River Defense on the Ming Great Wall: A Case Study of the Shanxi Section of the Yellow River by Tianlian WANG, Zhe LI

“…The spatial arrangement of river defence, represented by the Yellow River defence, embodies the ancient practice of adapting to local conditions, optimizing resource utilization, and transforming challenges into the guide of construction. …”
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Impact of Population-Based Screening for Diabetes and Prediabetes Among 67-Year-Olds Using Point-of-Care HbA1c on Healthcare Ultilisation, Results from the VISP Cohort by Andersen JW, Høgh A, Lindholt JS, Søgaard R, Støvring H, Yderstræde KB, Sandbæk A, Dahl M

“…These findings highlight the potential for screening to enhance disease management and underscore the need for strategies to optimize healthcare resource use following screening, especially for individuals without DM.Trial Registration: NCT03395509.Keywords: epidemiology, medication, general practice, Denmark, diabetes…”
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Early Postoperative Safety of Total Hip Arthroplasty in Systemic Lupus Erythematosus Patients by YANG Xingdong, YU Muyang, XU Yiming, ZHU Wei, HU Mingwei, WENG Xisheng, FENG Bin

“…To ensure the safety of THA surgery for patients with SLE, it is important to optimize the patient's condition and achieve stabilization prior to surgery. …”
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Clinical novel exploration of intractable fever in stroke rehabilitation: a single-center cross-sectional retrospective study by Huang Jingjie, Wu Bangqi, Qin Peng, Zhang Ziyi, Cheng Yupei, Wang Chaoran, Chen Yuyan, Bai Jing

“…Additionally, the study seeks to identify potential risk factors contributing to the development of intractable fever, aiming to guide clinical management and optimize treatment strategies for stroke-related fever. …”
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Episiotomies and obstetric anal sphincter injuries following a restrictive episiotomy policy in France: An analysis of the 2010, 2016, and 2021 National Perinatal Surveys. by Raphaele Houlbracq, Camille Le Ray, Béatrice Blondel, Nathalie Lelong, Anne Alice Chantry, Thomas Desplanches, ENP2021 Study Group

“…Further research is needed to predict the optimal rate of episiotomy for instrumental deliveries. …”
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Is intense exercise bad for your mind? Subjective, behavioral and physiological responses to a cognitive effort to failure by Darías Holgado, Ludovic Leubaz, Paolo Ruggeri, Guillermo Borragan, Antonio Luque-Casado, Tristan Bekinschtein, Daniel Sanabria, Nicolas Place

“…Discussion/Conclusion In conclusion, our study did not find evidence that short intense physical exercise negatively affected negatively the duration participants could sustain an adequate (or optimal) cognitive effort. However, it offers valuable insights into the dynamic nature of psychological and subjective states during such tasks. …”
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Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils by Yixiang Jiang, Ning Wang, Jingyi Liu, Haoran Ren, Wenkang Jiang, Yanting Lei, Xidan Fu, Miao Hao, Xiujuan Lang, Yumei Liu, Xijun Liu, Rui Li, Hulun Li

“…Abstract Background Stem cells utilized for ischemic stroke treatment often display unstable homing capabilities and diminished activity in vivo, limiting their neuroprotective efficacy. Furthermore, the optimal delivery route for stem cells remains undetermined. …”
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Effects of Mixing Ratio and Lactic Acid Bacteria Preparation on the Quality of Whole-Plant Quinoa and Whole-Plant Corn or Stevia Powder Mixed Silage by Chao He, Qian Li, Huaidong Xiao, Xuchun Sun, Zepeng Gao, Yuan Cai, Shengguo Zhao

“…The membership function analysis showed that the quality of mixed silage of WPQ with SP was better, and the optimal addition amount of SP was 0.6%. The results of Max and Mix on the quality improvement test of WPQ with WPC mixed silage showed that the two lactic acid bacteria formulations increased CP and AA content, and reduced NH₃-N/TN; pH was significantly lower than the control group (<i>p</i> < 0.01), and LA was significantly higher than the control group (<i>p</i> < 0.01). …”
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EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer by Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

“…We also evaluated and optimized a potential treatment strategy targeting NAT10. …”
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How to estimate the probability of a live birth after one or more complete IVF cycles? the development of a novel model in a single-center by Xiangyi Kong, Zhiqiang Liu, Chunyu Huang, Xiuyu Hu, Meilan Mo, Hongzhan Zhang, Yong Zeng

“…In the first to fifth FET cycle, the optimal estimate and conservative estimate CLBRs were 59.95%, 65.41%, 66.35%, 66.58%, 66.61% and 56.81%, 60.84%, 61.50%, 61.66%, 61.68%, respectively. …”
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Role of 18F-PSMA-1007 PET/CT-derived quantitative volumetric tumor parameters in cytoreductive radical prostatectomy selection for patients with low-volume metastatic hormone-sensi... by Junjie Fan, Ke Xu, Zhangdong Jiang, Chaosheng Gan, Hao Song, Guoqiang Gao, Guojing Wang, Qiyuan Kang, Liang Luo, Zhuonan Wang, Dalin He, XiaoYi Duan, Kaijie Wu

“…Results Among 122 patients, 37 (30.32%) underwent systemic therapy plus cRP. The median and optimal cutoff values of the whole-body PSMA-TV were 71.68 cm3 (41.28–157.41 cm3) and 78.57 cm3, respectively. …”
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Management control for quality in a hospitality business using ARP curves and the multivariate geometric indicator - Control de gestión para la calidad en una empresa hotelera con... by Tomás José Fontalvo Herrera, Juan José Tous Ferrigno, Fabio Mejía Zambrano

“…It introduces ARP operational curves and the multivariate geometric capacity indicator as tools to evaluate and optimize performance. Results: the premium and standard service lines achieved the highest Sigma Z levels, consistently exceeding 5. …”
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Biosynthesis and activity of Zn-MnO nanocomposite in vitro with molecular docking studies against multidrug resistance bacteria and inflammatory activators by Samy Selim, Tarek M. Abdelghany, Mohammed S. Almuhayawi, Mohammed K. Nagshabandi, Muyassar K. Tarabulsi, Mohammed Yagoub Mohammed Elamir, Asmaa A. Alharbi, Soad K. Al Jaouni

“…Extensive molecular docking studies were performed to identify the optimal location for manganese oxide and zinc oxide nanoclusters binding to MRSA. …”
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Effects on Soil Aggregates and Organic Carbon Under a Triple-Cropping System in the Middle Reaches of the Yangtze River by Binjuan Yang, Qin Liu, Ning Liu, Yao Huang, Guoqin Huang

“…In conclusion, in the triple-cropping area of paddy fields in the middle reaches of the Yangtze River, the milkvetch–early rice–sweet potato||late soybean and rape–early rice–sweet potato||late soybean models are conducive to the optimal management of the soil carbon pool and carbon sequestration. …”
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Effectiveness of artificial diet enriched by spinach extract on molting stimulation to produce soft shell crab by Siti Aslamyah, Yushinta Fujaya

“…This is apparently the effect of spinach extract as a stimulant molting, where performance can be optimized with a complete and balance nutrient composition. …”
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Hormonal induction of gonad maturation in female tinfoil barb fish (Barbonymus schwanenfeldii) using spawnprim hormone by Amalia Sutriana, Ahmad Baihaqi, Iwan Hasri, Nurliana, Hafizuddin Hafizuddin

“…Statistical analysis showed that the induction of spawnprim hormone on tinfoil barb broodstocks significantly affect (P<0.05) broodstock weight gain, egg diameter, and fecundity. The optimal dose of spawnprim hormone for tinfoil barb was 0.6 ml/kg body weight, with the average broodstock weight gain, egg diameter, and fecundity were 0.011 kg, 1.55 mm, and 102.15 eggs, respectively. …”
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Assessment of Lower Limb Muscle Volume Using 3D Ultrasonography: Validity and Reliability Compared to MRI by Paul Ritsche, Romina Ledergerber, Michele Pansini, Francesco Santini, Oliver Faude

“…Calibration refinements, including reduced probe pressure and optimized sweep protocols, are underway to improve accuracy. …”
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The Financial Implications of Pancreatic Surgery: The Hospital Is the Big Winner, Not the Surgeon! by Nitzan Zohar, MD, Avinoam Nevler, MD, Sean P. Maher, Matthew C. Rosenthal, Florence Williams, Wilbur B. Bowne, MD, FACS, Charles J. Yeo, MD, FACS, Harish Lavu, MD, FACS

“…High-volume pancreatic surgery centers require a significant investment in expertise, time, and resources to achieve optimal patient outcomes. A detailed understanding of the economics of major pancreatic surgery is limited among many clinicians and hospital administrators. …”
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