Organic rare earth feed additive to enhance Penaeus monodon’s muscle quality: A comprehensive insights into texture, amino acid, and fatty acid composition by Jiaoping Yu, Wanqi Wang, Guowei Liao, Zhen Zhang, Yuanyuan Yao, Kaimin Cheng, Jun Hu, Yalin Yang, Zhigang Zhou, Lanfen Fan

“…These results indicate that OREFA not only enhanced growth performance, but also improved muscle quality in P. monodon by optimizing amino acid and fatty acid composition, and promoting the expression of muscle growth-related genes. …”
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Tumor Deposits as an Adverse Prognostic Indicator in Stage III Colon Cancer: A Multicenter Database Study by Jeeyou Kim, MD, Dong Woon Lee, MD, Ji Won Park, MD, PhD, Seung-Bum Ryoo, MD, PhD, Heung-Kwon Oh, MD, PhD, Rumi Shin, MD, PhD, Jin Sun Choi, MD, Min Jung Kim, MD, Sung-Chan Park, MD, Duck-Woo Kim, MD, PhD, Seung Chul Heo, MD, PhD, Sung-Bum Kang, MD, PhD, Seung-Yong Jeong, MD, PhD, Kyu Joo Park, MD, PhD, Jae Hwan Oh, MD, PhD, On Behalf of the Seoul Colorectal Research Group (SECOG)

“…We explored the oncological impact of tumor deposits (TDs) on colon cancer and proposed optimal modifications to the current staging system. …”
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Protocol for Home-Based Solution for Remote Atrial Fibrillation Screening to Prevent Recurrence Stroke (HUA-TUO AF Trial): a randomised controlled trial by Jing Tan, Yan Liang, Yong Liu, Wei Jiang, Duo Huang, Ning Tan, Chung-Wah Siu, Jo Jo Hai, Xiaoyu Huang, Jianfeng Ye, Ji-yan Chen, Chun Ka Wong, Mi Zhou, Li-Xue Yin, Ming-Liang Zuo, Kui Kai Lau, Zhen Lei, Yingqing Feng, Bryan P Yan, Wen-Sheng Yue, Wen-Jun Zhang, Yuk-Ming Lau, Hin-Wai LUI, Koon-Ho Chan, Toi Meng Mok, Weng-Chio Tam, Kun-Chong Tam, Xiuhua Feng, Xiaofei Jiang, Guanming Tan, Mario Alberto Evora

“…Introduction Current international guidelines recommend ECG monitoring after an ischaemic stroke to detect atrial fibrillation (AF) in order to prevent stroke recurrence. However, optimal strategies to detect AF and the downstream management to prevent stroke recurrence remain to be established. …”
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Peripheral blood immunoinflammatory biomarkers: prospective predictors of postoperative long-term survival and chronic postsurgical pain in breast cancer by Baoli Li, Li Che, Huixian Li, Fangdi Min, Bolun Ai, Linxin Wu, Taihang Wang, Peixin Tan, Bingbing Fu, Jiashuo Yang, Yi Fang, Hui Zheng, Tao Yan

“…This study examined the predictive value of immunoinflammatory biomarkers for both long-term survival and CPSP.MethodsData on the clinicopathological characteristics and perioperative peripheral blood immunoinflammatory biomarkers of 80 patients who underwent breast cancer surgery were retrospectively collected. Optimal cut-off values for preoperative immunoinflammatory biomarkers, including the preoperative systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), neutrophil-to-lymphocyte ratio (NLR), and pan-immune-inflammation value (PIV), were established via receiver operating characteristic (ROC) curves. …”
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The state of combined thoracoabdominal triple-organ transplantation in the United States by Emily G. Dunbar, BS, Ye In Christopher Kwon, BA, Matthew Ambrosio, MS, Inna F. Tchoukina, MD, Keyur B. Shah, MD, David A. Bruno, MD, Walker A. Julliard, MD, Josue Chery, MD, Vigneshwar Kasirajan, MD, Zubair A. Hashmi, MD

“…A careful, multidisciplinary approach to patient selection and management remains paramount in optimizing outcomes for high-risk patients undergoing TOTs.…”
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Turning the Surface Electronic Effect Over Core‐Shell CoS2─FexCo1‐xS2 Nanooctahedra Toward Electrochemical Water Splitting in the Alkaline Medium by Lian‐Ming Lyu, Yu‐Chung Chang, Han‐Jung Li, Pei‐En Wang, Ruei‐Hung Juang, Ming‐Yen Lu, Cheng‐Shiuan Li, Chun‐Hong Kuo

“…Catalyzed by the CoS2, Fe0.25Co0.75S2, and Fe0.9Co1.0S2 {111} surfaces, the results of alkaline OER and HER indicated the Fe0.9Co1.0S2 the most superior activities by virtue of the optimized Fe─Co electronic effect. From the predictions by density functional theory (DFT) calculations in reaction thermodynamics, the energy barriers in OER and HER both follow the order of Fe0.9Co0.1S2(111) < Fe0.25Co0.75S2(111) < CoS2(111). …”
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A new pathogen pattern of acute respiratory tract infections in primary care after COVID-19 pandemic: a multi-center study in southern China by Heng Zhang, Deqi Meng, Hao Huang, Longhao Feng, Yushao Li, Yong Jiang, Ling Wang, Ruoyu Deng, Yuchun Sun, Binqin Chen, Fuzhao Liao, Yumei Wu, Huancai Zheng, Junling Ding, Maokun Chen, Cui Zeng, Wanting Zhao, Meng Hou, Yinyan Li, Zhishen Li, Haibo Xia, Kai Yang, Lingwei Wang

“…The microbiological evidences can optimize the precision diagnosis and treatment of ARTIs in primary care with limited resources.…”
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MOMENT registry: Patients with advanced non-small-cell lung cancer harboring MET exon 14 skipping treated with systemic therapy by Michael Thomas, Petros Christopoulos, Wade T Iams, Julien Mazieres, Alexis B Cortot, Nir Peled, Gabriele Minuti, Egbert F Smit, Francois Audhuy, Karin Berghoff, S Peter Eggleton, Frank Fries, Maike Hildenbrand, Peter Liu, Seyed Hamidreza Mahmoudpour, Christoph Menzel, Dina Oksen

“…Discussion/conclusion: The MOMENT registry collects comprehensive, high-quality real-world data from patients with METex14 skipping advanced NSCLC receiving systemic anticancer treatment in a routine clinical setting, to enable future studies informing regulatory decisions and optimal care for this rare population.…”

Candidate SNP-markers altering TBP binding affinity for promoters of the Y-linked genes CDY2A, SHOX, and ZFY are lowering many indexes of reproductive potential in men by M. P. Ponomarenko, E. B. Sharypova, I. A. Drachkova, L. K. Savinkova, I. V. Chadaeva, D. A. Rasskazov, P. M. Ponomarenko, L. V. Osadchuk, A. V. Osadchuk

“…Reproductive potential is the most important conditional indicator reflecting the ability of individuals in a population to reproduce, survive and develop under optimal environmental conditions. As for humans, the concept of reproductive potential can include the level of the individual’s mental and physical state, which allows them to reproduce healthy offspring when they reach social and physical maturity. …”
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Phase Transitions and Structural Evolution of Manganese Ores During High-Temperature Treatment by Ruslan Z. Safarov, Yerlan A. Baikenov, Assemgul K. Zhandildenova, Eldar E. Kopishev, Ruslan M. Kamatov, Jumat B. Kargin, H. Sanchez Cornejo, Crispin H. W. Barnes, Luis De Los Santos Valladares

“…These findings provide quantitative insights into optimizing manganese oxide phases for industrial applications, such as catalysts and pigments, and emphasize the impact of thermal treatment on phase stability and structural properties. …”
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A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024 by Saijilafu, Saijilafu, Ling-Chen Ye, Huanyi Li, Haokun Li, Xinyi Lin, Kehui Hu, Zekai Huang, Chimedragchaa Chimedtseren, Linjun Fang, Saijilahu, Ren-Jie Xu

“…Building on this analysis, the clinical application of CST regeneration should be optimized through interdisciplinary collaboration, enabling the exploration and validation of a variety of therapeutic approaches, including the use of neurotrophic factors, stem cell therapies, biomaterials, and electrical stimulation. …”
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Impact of gut microbial diversity on egg production performance in chickens by Liping Wu, Tao Zhang, Zhihua Luo, Huiyuan Xiao, Di Wang, Cailong Wu, Xinyan Fang, Jiawei Li, Jing Zhou, Junjie Miao, Hongli Tan, Yanan Wang, Qing Liu, Jianhua Huang

“…This research not only advances our understanding of avian gut microbiology but also has practical implications for optimizing poultry farming practices and enhancing economic outcomes.…”
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Characteristics of the smallest brucellaphage with strong lytic ability by Hongbaiyu Liu, Hongbaiyu Liu, Youhong Zhong, Zhihong Zhang, Kehong Xu, Kehong Xu, Chunpeng Mao, Chunpeng Mao, Qiuju Yang, Lihua Yang, Binbin Yu, Ying Long, Ying Long, Xinyu Qin, Xinyu Qin, Liyuan Shi, Sheng Chang, Yuanying Shen, Peng Wang

“…Transmission electron microscopy revealed that Y17 was composed of an icosahedral head (48.1 ± 2 nm) and a short tail (10.8 ± 1 nm), making it the smallest brucellaphage described so far. The optimal multiplicity of infection (MOI) for phage Y17 is 0.001, with a burst size of ~187 PFU/cell, the largest value reported for any brucellaphage, and it has a relatively short latent period. …”
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Prophylactic phage administration provides a time window for delayed treatment of vancomycin-resistant Enterococcus faecalis in a murine bacteremia model by Wei-Xiao Wang, Jiao-Yang Yu, Xiu-Zhen Chen, Xiu-Zhen Chen, Shi-Yong Fu, Hui Li, Peng-Cheng Yi, Yun-Yao Ren, Shuang-Lin Gu, Jing-Han Gao, Jing Fan, Yan-Mei Sun, Jie Feng, Shi-Wei Wang, Wei Chen, Wei Chen

“…However, critical gaps remain regarding optimal dosing, therapeutic design, and treatment timing for phage therapy targeting VRE-induced bacteremia.MethodsThe biological and genomic characteristics of a novel lytic phage specific to VRE were investigated. …”
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Safety and efficacy of oral edible bird’s nest supplementation: Anti-inflammatory and immunomodulatory benefits for Arabian race stallions during exercise by Khalid Obaid AL-Khaldi, Khalid Hamed Al-Ruzaiqi, Abdul Salam Babji, Seng Joe Lim, Mohammed Babatunde Sadiq, Nurhusien Yimer

“…Further studies should explore long-term effects and molecular mechanisms to optimize its use in equine sports.…”
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Salt tolerance evaluation and key salt-tolerant traits at germination stage of upland cotton by Mengjie An, Xinhui Huang, Yilei Long, Yin Wang, Yanping Tan, Zhen Qin, Xiantao Ai, Yan Wang

“…Therefore, in this study, 16 cotton samples with geographical representation were randomly selected from 308 cotton germplasms to determine the optimal 200 mmol·L-1 NaCl in cotton germination experiments. …”
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Computational identification of promising genetic markers associated with molecular mechanisms of reduced rice resistance to <i>Rhizoctonia solani</i> under excess nitrogen fertili... by E. A. Antropova, A. R. Volyanskaya, A. V. Adamovskaya, P. S. Demenkov, I. V. Yatsyk, T. V. Ivanisenko, Y. L. Orlov, Ch. Haoyu, M. Chen, V. A. Ivanisenko

“…This study opens prospects for developing innovative strategies in rice breeding aimed at optimizing the balance between yield and disease resistance in modern agrotechnical conditions.…”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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Construction of a Compound Model to Enhance the Accuracy of Hepatic Fat Fraction Estimation with Quantitative Ultrasound by Zsély Boglárka, Zita Zsombor, Aladár D. Rónaszéki, Anna Egresi, Róbert Stollmayer, Marco Himsel, Viktor Bérczi, Ildikó Kalina, Klára Werling, Gabriella Győri, Pál Maurovich-Horvat, Anikó Folhoffer, Krisztina Hagymási, Pál Novák Kaposi

“…We searched a QUS parameter grid to find the optimal thresholds (AC ≥ 0.84 dB/cm/MHz, BSC-D ≥ 105), above which switching from a linear (r = 0.752, ICC = 0.715) to a nonlinear multivariable (r = 0.719, ICC = 0.641) model could improve the overall fit (r = 0.775, ICC = 0.718). …”
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Healthy food prescription incentive programme for adults with type 2 diabetes who are experiencing food insecurity: protocol for a randomised controlled trial, modelling and implem... by Colleen Norris, Tyler Williamson, Richard Oster, Dana Lee Olstad, Laura White, David J T Campbell, Sharlette Dunn, Kim D Raine, Mary L'Abbé, Richard Lewanczuk, Lorraine L Lipscombe, Eldon Spackman, Reed Beall, Kienan Williams, Sara Scott, Gabrielle L Zimmermann, Kerry A McBrien, Kieran J D Steer, Catherine B Chan, Sheila Tyminski, Seth Berkowitz, Alun L Edwards, Terry Saunders-Smith, Saania Tariq, Naomi Popeski, Sara Nejatinamini, Aruba Naser, Carlota Basualdo-Hammond, Petra O’Connell, Judy Seidel, Jason Cabaj

“…Introduction The high cost of many healthy foods poses a challenge to maintaining optimal blood glucose levels for adults with type 2 diabetes mellitus who are experiencing food insecurity, leading to diabetes complications and excess acute care usage and costs. …”
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