Efficacy of intranasal naloxone compared to other administration routes in prehospital opioid overdose management and beyond: a narrative review by Luigi Venuso, Francesco Ricciardi, Antonio Del Prete, Michele Virgolesi, Gianluca Pucciarelli, Luigi Langella, Teresa Rea

“…These findings emphasize the need for further research on optimizing naloxone dosing for synthetic opioid emergencies. …”
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Insights into salinity effect on growth of the spotted scat (Scatophagus argus): Exploring the optimum salinity for its culture by Maoliang Su, Zhanquan Feng, Youling Zhong, Zhiyin Ye, Junbin Zhang

“…A “U-shaped” relationship between salinity and final weight was revealed through regression analysis, and it was deduced that the optimal salinity for the growth of S. argus juveniles was 17.40 ppt. …”
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Analisis Sistem Pelaksanaan Kelas Ibu Hamil di Puskesmas Malalak dan Biaro Kabupaten Agam by Ayu Nurdiyan, Desmiwarti ., Rizanda Machmud

“…Necessary effort to optimize and expand antenatal class implementation.…”
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Real-world treatment patterns of patients with acute coronary syndrome based on 15-year data by Inga S. Egorova, Natalia N. Vezikova

“…BACKGROUND: About half a million cases of acute coronary syndrome (ACS) are diagnosed in Russia every year. However, despite optimized treatment of patients with ACS, mortality remains high, which dictates the need to analyze the effectiveness of therapeutic measures. …”
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Effects of cassava pellets and enzymes addition on growth performance, meat quality, serum biochemical indices and cecum microbiota of broilers by Dan Yue, Ying Lu, Jin Zhao, Xiaoming He, Junhong Zhu, Jiawei Liang, Weidong Deng

“…The addition of 10 % cassava pellets to the diet improved the growth performance and meat quality of broilers from 1 to 21 days of age and enhanced the microbial composition, providing valuable insights for optimizing broiler diets and improving economic returns.…”
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Petrophysical assessment of the Hammam Faraun, Matulla and Nubia Reservoirs in the Ashrafi Oil Field, Gulf of Suez by Mohammed Amer, Walid M. Mabrouk, Amr M. Eid, Ahmed Metwally

“…This thorough analysis enhances our understanding of the geological framework and serves as a vital resource for optimizing hydrocarbon recovery and guiding exploration initiatives in the Ashrafi Oil Field. …”
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Research on Monitoring Methods for the Appropriate Rice Harvest Period Based on Multispectral Remote Sensing by Chen Cong, Cao Guangqiao, Li Yibai, Liu Dong, Ma Bin, Zhang Jinlong, Li Liang, Hu Jianping

“…The accuracy of the inversion model with different input variables and model methods was evaluated, and the optimal inversion model for rice moisture content and thousand-grain weight was selected, which could be used to determine whether the crop was harvested during the appropriate period. …”
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Grid-Scale Battery Systems for VAR Support in Con Edison Distribution Substations via Bi-Directional Smart Inverters by Mohamed K. Kamaludeen, Yusef Esa, Kirn Zafar, Elihu Nyemah, Ahmed Ali A. Mohamed, Tamer Ibrahim, Simon Odie

“…Various scenarios were examined to ascertain the optimal inductive filter size that balances the BESS’s real and reactive power outputs. …”
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A Localized Model for Branding in the Iranian Dairy Industry by Shaghayegh Sabaghi, Alireza Rousta, Farzad Asayesh

“…Regarding causal conditions, two main categories including marketing mix, mental paradigms of managers, social responsibility, optimal mining, and organizational culture were identified. …”
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Ejaculatory abstinence duration impacts semen parameters: Insights from a retrospective analysis in male infertility on 23,527 analyses by Giorgio Ivan Russo, Maria Giovanna Asmundo, Andrea Cocci, Ali Saber Abdelhameed, Annalisa Liprino, Filippo Giacone, Debora Lombardo, Antonino Guglielmino, Sandrine Chamayou

“…Interestingly, we found a significant trend decrease of motility (A+B) (28.0% vs. 21.0%; p<0.01) and pH (8.1 vs. 7.9; p<0.01) In patients affected by asthenospermia, motility (A+B) dropped significantly from day 1 to day 7 (11.8% vs. 6.1%; p<0.01) and also in patients with teratospermia morphology dropped significantly (2.13% vs. 1.26%; p<0.01).ConclusionThe findings support the use of tailored abstinence guidelines to optimize semen quality based on patient-specific semen profiles, with normospermic men benefiting from longer abstinence durations to increase concentrations, while patients with motility or morphology impairments, may benefit from shorter abstinence periods to mitigate sperm quality declines.…”
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Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A Formulation Study by Zucca G, Vigani B, Valentino C, Ruggeri M, Marchesi N, Pascale A, Giovilli G, Malavasi L, Sandri G, Rossi S

“…N3 (0.5 mg/mL; lCH=1.5:1; pH = 5) and N9 (0.5 mg/mL; lCH=1:1; pH = 5) showed optimal characteristics, including small size (< 350 nm) and positive zeta potential, facilitating cellular uptake. …”
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Pengembangan Aplikasi Sistem Penilaian Praktik Pengalaman Lapangan pada Fakultas Ilmu Komputer Universitas Brawijaya Berbasis Web by Rizky Tri Sulistyo, Faizatul Amalia, Tri Afirianto

“…So it is necessary to optimize the management in the FEP assessment system with a web-based FEP assessment system application solution that can be accessed from any browser. …”
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Verbal paired associates learning lateralizes left hippocampal sclerosis in temporal lobe epilepsy by Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Angela R. Jackman, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby

“…PAL Hard Pairs and all RAVLT indices displayed acceptable discriminatory ability (AUC > 0.70) in classifying left‐sided HS (unilateral left or bilateral HS), with RAVLT delayed recall the strongest predictor (AUC = 0.87; PAL Hard Pairs Learning and Delay = 0.80 and 0.83, respectively). Optimal cutoff scores for left‐sided HS classification were generated. …”
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Spatiotemporal analysis of oil palm land clearing by M.K. Rosyidy, E. Frimawaty

“…The most significant increase occurred in 2016-2017, around 38,889 hectares.CONCLUSION: This study demonstrates that using Landsat 8 imagery combined with GIS approaches provides the optimal method for an in-depth analysis of land cover changes related to oil palm expansion and land clearing that occur on a broader spatial scale and temporal in Jambi Province. …”
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Randomised controlled trial of topical kanuka honey for the treatment of rosacea by James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Janwillem Kocks, Mark Holliday, Andrew Corin, Colin Helm, Davitt Sheahan, Barney Montgomery, Judith Riley, Anna Hunt, Christopher Tofield

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Integrating urban building information modeling and circular economy framework for green sustainability by N. Andriyani, P. Suprobo, T.J.W. Adi, W.A.N. Aspar, A.D. Jatmiko, A.D. Santoso

“…Autodesk Revit streamlines waste estimation and inventory of reusable, repairable, refurbished, and recyclable waste, thereby optimizing waste management planning with improved effectiveness and efficiency. …”
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Combination of reverse shock index and simplified motor score as a strong discriminator of trauma outcomes by Meng-Yu Wu, Giou-Teng Yiang, Ding-Kuo Chien, Sy-Jou Chen, Chi-Ming Chu, Jui-Yuan Chung, Hon-Ping Ma, Mau-Roung Lin

“…In patients with mixed and isolated brain injuries, rSI-sMS accurately discriminated the four clinical outcomes, similar to rSI-GCS. The optimal cutoff value of rSI-sMS had a discriminant ability of 85.0, 78.6, 75.2, and 81.0% for in-hospital mortality, ICU admissions, ICU stay ≥14 days, and hospital stays of ≥30 days, respectively.Conclusions Compared with the shock index, modified shock index, and rSI-GCSM, rSI-sMS is a more accurate field triage scoring system for discriminating in-hospital mortality, ICU admissions, prolonged ICU stay, and prolonged hospital stays in patients with trauma.…”
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Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This would suggest that education and self-management skills should be seen as an integral component of asthma management and should be incorporated in structured patient care to achieve optimal asthma control.…”
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Influence of Extra-Articular Augmentation on Clinical Outcomes and Survival in Patients Undergoing Anterior Cruciate Ligament Reconstruction: A Pseudorandomized Study by Antonio Maestro, Nicolás Rodríguez, Iván Pipa, Carmen Toyos, Lucía Lanuza, Filipe Machado, César Castaño, Santiago Maestro

“…Our objective is to compare the results of these techniques, with a primary focus on assessing knee stability and graft survival, to provide evidence for optimizing surgical approaches, particularly for athletes and physically active individuals. …”
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The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection by Qingqing Chen, Haohao Wu, Xinwei Guo, Ke Gu, Wenjie Wang, Xiaochen Chen, Shengjun Ji, Hui Yang, Jiahao Zhu

“…Based on the patient data, the receiver operating characteristic (ROC) optimal cutoff value of ∆SII was 127.7 for OS prediction. …”
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