Effect of Transcranial Direct-Current Stimulation and Task-Oriented Training on Electroencephalography-Based Motor Recovery Chronic Stroke: A Randomized Clinical Trial by Maryam Zolghadr, Shohreh Noorizadeh Dehkordi, Javad Sarrafzadeh, Saeed Talebian, Hassan Haddadzade Niri, Marzieh Yassin

“…Due to the inconsistent effects of tDCS on the EEG power spectrum in stroke patients, conventional tDCS administration may require adjustments for optimal application to brain target points. …”
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Oxidative Stress and Risk of Dementia in Older Patients with Depression: A Longitudinal Cohort Study Using Plasma Biomarkers by Yoo-Jin Jang, Min-Ji Kim, Su-Jin Lee, Shinn-Won Lim, Doh-Kwan Kim

“…The log-rank test, using the minimum <i>p</i>-value approach, was applied to determine the optimal cut-off value for significantly associated biomarkers of AD-free survival rates. …”
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«No-reflow» phenomenon and risk factors associated with its development after primary percutaneous coronary interventions in patients with ST elevation myocardial infarction by V.І. Tseluyko, M.M. Doloh, O.A. Leonenko

“…NRP was determined after recanalization of the infarct-associated coronary artery as the absence of optimal myocardial perfusion using MBG (Myocardial Blush Grade, MBG ≤ 2) scale. …”
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Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review. by Maylis Layan, Simon Dellicour, Guy Baele, Simon Cauchemez, Hervé Bourhy

“…Developing a detailed understanding of dog rabies dynamics and the impact of vaccination is essential to optimize existing control strategies and developing new ones. …”
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Genetic trends and common BRCA1/2 pathogenic sequence variants in black African and Indian breast cancer patients presenting at Inkosi Albert Luthuli Central Hospital, KwaZulu-Nata... by M Makhetha, C Aldous, N Chabilal

“…This study highlights unique genetic trends for SA populations and the need for more inclusive targeted tests that are optimal for these populations. …”
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Systematic approach to paired ceramic coatings deposited by oxygen fuel and metal in a tribological application by K.A. Habib, D.L. Cano, Emilo Rayón, J. Serrano-Mira, José V. Abellán-Nebot, I. Cervera

“…In summary, this work analysed the friction and wear properties of four ceramic coatings and their counterpart metallic discs under lubrication conditions using Stribeck curve, to provide an experimental basis for screening optimal materials for the key friction and wear pairs of industrial design and applications. …”
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Psychological and autonomous nervous system features of functional gastric dyspepsia and irritable bowel syndrome, duloxetine treatment efficacy by A. P. Pogromov, G. M. Dyukova, M. L. Leonova

“…Further studies for estimation of optimal dose and duration of treatment are requires.…”
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Left Ventricular End-Systolic Volume Is a Reliable Predictor of New-Onset Heart Failure with Preserved Left Ventricular Ejection Fraction by Marina Kato, Shuichi Kitada, Yu Kawada, Kosuke Nakasuka, Shohei Kikuchi, Yoshihiro Seo, Nobuyuki Ohte

“…According to the receiver-operating characteristic curve analysis for adverse events, log BNP level of 3.23 pg/ml (BNP level: 25.3 pg/ml) and an LVESVI of 24.1 ml/m2 were optimal cutoff values (BNP : AUC : 0.753, p<0.001, LVESVI : AUC : 0.729, p<0.001, respectively). …”
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Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve by Ramona Schmitt, Anke Tscheuschler, Philipp Laschinski, Philipp Discher, Jana Fuchs, Fabian A. Kari

“…This result is important for further studies as it will be essential to specify the location of samples to ensure data comparability regarding the main goals of understanding the pathogenesis of aTAA, optimizing treatments, and establishing a screening method for its potentially deadly complications.…”
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Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation by María del Pilar Diego-Santiago, María Ujué González, Esther María Zamora Sánchez, Nuria Cortes-Carrillo, Carlos Dotti, Francesc Xavier Guix, Sahba Mobini

“…We identified accumulated charge and effective electric field time as novel criteria for determining optimal ES regimes. ES parameters were obtained using electrochemical characterisation and equivalent circuit modelling. …”
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Fortifying plant fortresses: siderophores in defense against Cercospora leaf spot disease in Vigna radiata L. by Anushree Kamath, Abhishek Sharma, Arpit Shukla, Arpit Shukla, Arpit Shukla, Paritosh Parmar, Dhara Patel

“…Field trials are essential to validate these results under natural conditions and optimize their use in agriculture.…”
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High-Performance Photocatalytic Multifunctional Material Based on Bi₄Ti₃O₁₂-Supported Ag and Ti₃C₂T_x for Organic D... by Kexi Zhang, Bingdong Yan, Xiaohong Wang, Yang Cao, Wanjun Hao, Jinchun Tu

“…We discovered that the addition of Ag and Ti₃C₂T_x effectively optimized the visible light absorption characteristics of BTO, reduced the electron transfer resistance, and increased the carrier concentration, thus significantly improving the photocatalytic performance of composite material, thereby markedly improving the composite’s photocatalytic performance and its efficacy in photochemical sensing and photodegradation. …”
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Enhanced CyGNSS Soil Moisture Retrieval Validated by In-Situ Data in Argentina&#x0027;s Pampas by Javier Arellana, Francisco Grings, Mariano Franco

“…We observe that both the in-situ measurements of <inline-formula><tex-math notation="LaTeX">$\varepsilon _{1}$</tex-math></inline-formula> and the reflectivity reported by CyGNSS align with the optimal values obtained from the fit, resulting in a 73&#x0025; reduction in root mean square error when compared to the traditional approach. …”
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Participant Compliance With Ecological Momentary Assessment in Movement Behavior Research Among Adolescents and Emerging Adults: Systematic Review by Shirlene Wang, Chih-Hsiang Yang, Denver Brown, Alan Cheng, Matthew Y W Kwan

“…Findings also highlight the need for greater consistency in reporting and more specificity when explaining procedures to understand how EMA compliance could be optimized in studies examining physical activity and sedentary time among youth. …”
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Evolving racial/ethnic disparities in AML survival in the novel therapy era by Xin Wang, Phyllis A. Gimotty, Andrew H. Matthews, Ronac Mamtani, Selina M. Luger, Elizabeth O. Hexner, Daria V. Babushok, Shannon R. McCurdy, Noelle V. Frey, Ximena Jordan Bruno, Saar Gill, Mary Ellen Martin, Vikram R. Paralkar, Ivan Maillard, David L. Porter, Alison W. Loren, Alexander E. Perl, Keith W. Pratz, Kelly D. Getz, Catherine Lai

“…Additional studies are needed to elucidate factors contributing to these observed survival differences and to inform strategies to optimize outcomes for all patients with AML.…”
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Verifying the Usefulness of Pulmonary Blood Flow Studies in the Correction of Pulmonary Atresia and Ventricular Septal Defect with Major Aortopulmonary Collateral Arteries by Zirou Huang, Fan Cao, Rongjun Zou, Minghui Zou, Weidan Chen, Wenlei Li, Guodong Huang, Li Ma, Xinxin Chen

“…The maximum Youden’s index was 0.713, which corresponded to an optimal mean pulmonary artery pressure cutoff value of 24.5 mmHg. …”
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Image-based robotic (ROSA® knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty by Henriëtte M. Eijking, Isobel M. Dorling, Emil H. van Haaren, Roel Hendrickx, Thijs Nijenhuis, Martijn G.M. Schotanus, Lee Bouwman, Jasper Most, Bert Boonen

“…Relatively high rates of dissatisfactory results after total knee arthroplasty (TKA), as reported by approximately 20% of patients, may be caused by sub-optimal knee alignment and balancing. While mechanical alignment has traditionally been the goal, patient-specific alignment strategies are gaining interest. …”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…This knowledge may help to optimize the combination of the selected IMQ dose with e.g. chemotherapy or radiotherapy to elicit synergistic effect in cancer treatment. …”
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Evolution of Treatment Outcomes and Prognostic Factors in Esophageal Cancer Surgery: A Retrospective Analysis of 1500 Consecutive Esophagostomies by Yasue Kimura, MD, PhD, Eiji Oki, MD, PhD, Tomonori Nakanoko, MD, PhD, Qingjiang Hu, MD, PhD, Keita Natsugoe, MD, Sho Nanbara, MD, PhD, Ryota Nakanishi, MD, PhD, Yuichiro Nakashima, MD, PhD, Mitsuhiko Ota, MD, PhD, Tomoharu Yoshizumi, MD, PhD

“…These findings will help optimize esophageal cancer management and improve patient outcomes.…”
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Study of interfacial bonding properties and shrinkage deformation of cement-alkali activated gradient-structured composite in complex environments with temperature-humidity changes by Xinzhe Li, Ganyou Jiang, Naishuang Wang, Yisong Wei, Zheng Chen, Zheng Chen, Jing Li, Jing Li, Ben Chen, Ben Chen, Jiamin Yu, Jiamin Yu

“…This study provides some references for the optimal design of the early shrinkage-deformation properties and mechanical properties of gradient-structured composites under extreme environments as well as the assessment of service life.…”
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