Prospective Evaluation of Results of Surgical Treatment of Patients with Idiopathic Macular Hole by Phacovitrectomy and Combined Cataract and Vitrectomy Surgery by Kinga Tochman-Kanty, Monika Jasielska, Jerzy Mackiewicz

“…At subsequent check-ups, the subjects underwent a complete ophthalmological examination, which included: best corrected distance visual acuity and best corrected near visual acuity, assessment of the anterior and posterior segments, in a slit lamp, measurement of retinal sensitivity in the macula using microperimetry, the Amsler test and optical coherence tomography examination of the macula. …”
Get full text

State-of-the-art of loading and unloading tests for glaucoma: potentialities and informative value by O.S. Myakonkaya, A.S. Sarkisyan, A.V. Seleznev, A.V. Kuroyedov, I.R. Gazizova

“…Petersburg, Russian Federation</b> </p> <p> <i>Prevention of blindness and low vision resulting fr om the progression of glaucomatous optic neuropathy (GON) depends mainly on the early diagnosis of glaucoma. …”
Get full text

Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity by Yang Wang, Jianguo Xu, Wanchun You, Haitao Shen, Xiang Li, Zhengquan Yu, Haiying Li, Gang Chen

“…The SAH rat model was induced by infusing autologous blood into the optic chiasma pool and treating the rats with lentivirus-negative control 1 (LV-NC1), lentivirus-Rufy3 shRNA (LV-shRNA), lentivirus-negative control 2 (LV-NC2), lentivirus-Rufy3 (LV-Rufy3), or 8-pCPT-2′-O-Me-cAMP (8p-CPT) (Rap1 agonist). …”
Get full text

Structure-Function Relationship between Cluster Mean Defect and Sector Peripapillary Retinal Nerve Fiber Layer Thickness in Primary Open Angle Glaucoma by Jing Han, Wenjiu Yang, Dabo Wang, Haiqing Bai

“…To determine the structure–function relationship between cluster mean defect (MD) offered by standard automated perimetry and corresponding sector peripapillary retinal nerve fiber layer thickness (pRNFLT) measured with optical coherence tomography (OCT) in primary open angle glaucoma (POAG). …”
Get full text

Screening and Identification of Cold-Tolerant Phosphorus and Potassium Solubilizing Bacteria and Their Growth-Promoting Effects on Soybean in Cold Regions by Hao Yan, Tianyi Wang, Haocheng Wang, Nan Sun, Xuebing Wang, Xingbo Zhao, Zhongbao Yao, Hao Tian, Shengjie Chen, Songyan Tang, Chenyang Li

“…The OD₆₀₀ value (optical density of 600 nm) on the 10th day was 0.61. …”
Get full text

Glaucoma Detection and Feature Identification via GPT-4V Fundus Image Analysis by Jalil Jalili, PhD, Anuwat Jiravarnsirikul, MD, Christopher Bowd, PhD, Benton Chuter, MD, Akram Belghith, PhD, Michael H. Goldbaum, MD, Sally L. Baxter, MD, Robert N. Weinreb, MD, Linda M. Zangwill, PhD, Mark Christopher, PhD

“…Methods: Preprocessing ensured each image was centered on the optic disc. GPT-4's vision-preview model (GPT-4V) assessed each image for various glaucoma-related criteria: image quality, image gradability, cup-to-disc ratio, peripapillary atrophy, disc hemorrhages, rim thinning (by quadrant and clock hour), glaucoma status, and estimated probability of glaucoma. …”
Get full text

Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration by Ping-Wu Zhang, Zi-He Wan, Weifeng Li, Abhishek Vats, Kunal Mehta, Laura Fan, Lingli Zhou, Sean Li, Gloria Li, Casey J. Keuthan, Cynthia Berlinicke, Cheng Qian, Noriko Esumi, Elia J Duh, Donald J. Zack

“…Retinal structure and function were evaluated by spectral-domain optical coherence tomography (SD-OCT) and electroretinography (ERG). …”
Get full text

Prospective Analysis of Confocal Laser Endomicroscopy for Assessment of the Resection Bed for Bladder Tumor by Ben-Max de Ruiter, Jan E. Freund, C. Dilara Savci-Heijink, Jons W. van Hattum, Marinka J. Remmelink, Theo M. de Reijke, Joyce Baard, Guido M. Kamphuis, D. Martijn de Bruin, Jorg R. Oddens

“…Confocal laser endomicroscopy (CLE), a probe-based optical technique for real-time microscopic evaluation, has shown promising accuracy for grading of UCB. …”
Get full text

Berberine alleviates enterotoxigenic Escherichia coli-induced intestinal mucosal barrier function damage in a piglet model by modulation of the intestinal microbiome by Min Du, Xinran Liu, Xu Ji, Yue Wang, Xiaodan Liu, Chunfang Zhao, Chunfang Zhao, Erhui Jin, Erhui Jin, Youfang Gu, Youfang Gu, Hongyu Wang, Feng Zhang, Feng Zhang

“…Furthermore, berberine increased the optical density of mucin 2 and the mucin 2, P-glycoprotein, and CYP3A4 mRNA expression levels (P &lt; 0.05). …”
Get full text

Surgical treatment of small- and medium-sized primary macular holes with preservation of the internal limiting membrane in the papillomacular nerve fiber bundle area by N.M. Shilov, A.V. Tereshchenko, E.V. Erokhina, S.V. Novikov, A.A. Lugovaya, A.G. Kurguzova

“…The preservation of the foveolar part of the ILM and its fragment in the projection of the PMB resulted in a high functional outcome, as evidenced by BCVA (20/25 at 12 months after surgery) and microperimetry, which showed an increase in retinal light sensitivity and disappearance of the absolute scotoma in the central fovea in all patients in the postoperative period. Spectral optical coherence tomography showed multiple defects of the inner retinal layers in the perifovea of varying severity, corresponding to the area of ILM peeling and not involving the papillomacular area. …”
Get full text

Development of a new nanobiotechnology method for the differential diagnosis of ocular adnexal tumors by S.V. Saakyan, D.A. Skladnev, A.P. Alekseeva, O.V. Beznos, V.V. Sorokin

“…Obtaining the most significant changes in the optical density of the reaction mixture with biogenic nanoparticles required 10 to 20 min, although the first changes were documented starting from the 5th minute of the reduction reaction. …”
Get full text

Self‐Boosting Programmable Release of Multiple Therapeutic Agents by Activatable Heterodimeric Prodrug‐Enzyme Assembly for Antitumor Therapy by Shanshan Jiang, Bhaskar Gurram, Junfei Zhu, Shan Lei, Yifan Zhang, Ting He, Oya Tagit, Hui Fang, Peng Huang, Jing Lin

Get full text

Effects of Electroacupuncture Preconditioning at Baihui and Zusanli Acupoints on the Expression of Inflammatory Factors in Brain and Intestines of Rats with Cerebral Ischemia/Reper... by ZHANG Jiyao, TANG Qiang, ZHU Luwen

“…Before surgery for one day, after reperfusion for 12 h and after reperfusion for 1,3,7 days, the grip tester was used to measure the forelimb grasping strength; after reperfusion for 7 days, ELISA methods was used to determine the content of IL-17A and IL-10 in serum, Western blot method was used to detect the expression of IL-17A and IL-10 protein in ischemic cortex and colon tissue, immunohistochemistry method was used to calculate the average optical density (AOD) value of IL-17A and IL-10 in ischemic cortex and colon tissue, and HE staining method was used to observe the pathological change of ischemic cortex.Results① Forelimb grasping strength: compared with the S-con group, the forelimb grasping strength of rats in the M-con group after reperfusion for 12 h, 1 d, 3 d, 7 d was decreased significantly (<italic>P</italic>&lt;0.05); compared with the M-con group, the forelimb grasping strength of rats in the EP group was increased significantly (<italic>P</italic>&lt;0.05). ② Content of IL-17A and IL-10 in serum: after reperfusion for 7 days , compared with the S-con group, the content of serum IL-17A and IL-10 of rats in the M-con group were significantly increased (<italic>P</italic>&lt;0.05); compared with the M-con group, the content of serum IL-17A in the EP group were significantly decreased (<italic>P</italic>&lt;0.05), and IL-10 in the EP group were significantly increased (<italic>P</italic>&lt;0.05). ③ Expression of IL-17A and IL-10 protein: after reperfusion for 7 days, compared with the S-con group, the expression of IL-17A and IL-10 protein in ischemic cortex and colon tissue in the M-con group were significantly increased (<italic>P</italic>&lt;0.05); compared with the M-con group, the expression of IL-17A in the EP group was significantly decreased (<italic>P</italic>&lt;0.05), and the expression of IL-10 protein in the EP group was significantly increased (<italic>P</italic>&lt;0.05). ④ AOD value of IL-17A and IL-10: after reperfusion for 7 days, compared with the S-con group, the AOD value of IL-17A and IL-10 in ischemic cortex and colon tissue in the M-con group were significantly increased (<italic>P</italic>&lt;0.05); compared with the M-con group, the AOD value of IL-17A in the EP group was significantly decreased (<italic>P</italic>&lt;0.05), the AOD value of IL-10 in the EP group was significantly increased (<italic>P</italic>&lt;0.05). ⑤ Pathological change of ischemic cortex: after reperfusion for 7 days, compared with the M-con group, the pathological change of ischemic cortex in EP group was significantly decreased (<italic>P</italic>&lt;0.05).ConclusionElectroacupuncture preconditioning at Baihui and Zusanli acupoints can reduce the pathological damage degree of the ischemic cortex and intestinal-central inflammation, improve neurobehavioral function, which may be related to brain-gut protection.…”
Get full text

A pulsed carbon dioxide laser-induced breakdown analysis for chemical profile of tsunami-affected soil by R. Mitaphonna, N. Idris, M. Ramli, N. Ismail, K. Kurihara, K. Lahna

“…Plasma was produced by concentrating a pulsed carbon dioxide laser beam on the surface samples. An optical multichannel analyzer captures plasma emissions with a spectrograph and photodiode array. …”
Get full text

Alpha-adrenergic receptor agonists in terms of modern views on glaucoma monitoring and treatment by V.P. Erichev, S.Yu. Petrov, A.V. Volzhanin, D.M. Safonova, T.V. Yaremenko, S.A. Kazaryan

“…Brimonidine prevents ganglionic cell death in glaucomatous optic neuropathy. Several in vitro and in vivo studies describe the mechanism of preventing mitochondrial dysfunction and excitotoxic retinal cell damage in ischemia. …”
Get full text

The initial results of using brolucizumab (Beovu®), an angiogenesis inhibitor, for choroidal neovascularization in patients with age-related macular degeneration by N.S. Zhayvoronok, O.V. Kolenko, L.P. Danilova, E.L. Sorokin

“…The dynamic monitoring included optical coherence tomography to assess the localization and area of the neovascular complex, as well as the density and thickness of the new blood vessels (OCT-angiography). …”
Get full text

Gaia-4b and 5b: Radial Velocity Confirmation of Gaia Astrometric Orbital Solutions Reveal a Massive Planet and a Brown Dwarf Orbiting Low-mass Stars by Gudmundur Stefánsson, Suvrath Mahadevan, Joshua N. Winn, Marcus L. Marcussen, Shubham Kanodia, Simon Albrecht, Evan Fitzmaurice, Onė Mikulskytė, Caleb I. Cañas, Juan I. Espinoza-Retamal, Yiri Zwart, Daniel M. Krolikowski, Andrew Hotnisky, Paul Robertson, Jaime A. Alvarado-Montes, Chad F. Bender, Cullen H. Blake, J. R. Callingham, William D. Cochran, Megan Delamer, Scott A. Diddams, Jiayin Dong, Rachel B. Fernandes, Mark R. Giovinazzi, Samuel Halverson, Jessica Libby-Roberts, Sarah E. Logsdon, Michael W. McElwain, Joe P. Ninan, Jayadev Rajagopal, Varghese Reji, Arpita Roy, Christian Schwab, Jason T. Wright

Get full text

Crack of a helicopter main rotor actuator attachment: failure analysis and lessons learned by L. Allegrucci, F. De Paolis, A. Coletta, M. Bernabei

“…Fracture surfaces were examined by optical and electronic microscopy in order to determine the main morphological features and consequently to trace the origin of failure mechanism and causes. …”
Get full text

Clinical and genetic characteristics of a total or partial congenital aniridia by N.V. Sukhanova, V.V. Kadyshev, T.A. Vasilieva, A.V. Marakhonov, L.A. Katargina, S.I. Kutsev, R.A. Zinchenko

“…Partial CA was significantly more prevalent in patients with splice-site mutations (p=0.004996) as compared to other mutation types. Optic nerve hypoplasia (p=0.04779), internal strabismus (p=0.010882), aniridia-associated keratopathy co-occurring with LSCD (p=0.013236) were diagnosed more frequently in patients with nonsense mutations. …”
Get full text

The first experience with brolucizumab for neovascular age-related macular degeneration by A.N. Kulikov, D.S. Maltsev, A.Yu. Malafeeva, S.M. Perminova, V.R. Zhalimova, A.S. Vasiliev, A.A. Kazak

“…</i> </p> <p> <i><b>Keywords</b>: age-related macular degeneration, brolucizumab, optical coherence tomography, anti-VEGF therapy.</i> </p> <p> <i><b>For citation:</b> Kulikov A.N., Maltsev D.S., Malafeeva A.Yu. et al. …”
Get full text