Opioids in Chronic Noncancer Pain: More Faces from the Crowd by C Peter N Watson

“…BACKGROUND: The use of opioids for chronic noncancer pain (CNCP) remains very controversial. …”
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Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis by Konstantinos A. Kontoangelos, Anastasios V. Kouzoupis, Panagiotis P. Ferentinos, Ioannis D. Xynos, Nikolaos V. Sipsas, George N. Papadimitriou

“…After chronic treatment with opioids, we administered pregabalin at a dose of 300 mg as an analgesic agent while opioids were discontinued. …”
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The Analgesic Effect of Morphine on Peripheral Opioid Receptors: An Experimental Research by Jafal Nader-Mugurel, Stoleru Smaranda, Zugravu Aurelian, Orban Carmen, Popescu Mihai, Marin Ruxandra Cristina, Fulga Ion-Gigel

“…Opioids represent one of the key pillars in postoperative pain management, but their use has been associated with a variety of serious side effects. …”
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Opioid Prescription Patterns for Discharged Patients from the Emergency Department by Justin Yanuck, Jonathan B. Lee, Soheil Saadat, Jila Rouhi, Ghadi Ghanem, Bharath Chakravarthy, Shalini Shah

“…Context. Opioid prescriptions from the emergency department (ED) have gradually increased over the last 20 years. …”
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Opioid Prescribing Trends by Croatian Dentists - Is there a Reason for Concern? by Lara Vranić, Krešimir Bašić, Ivana Šutej

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Opioid Dependent and Pregnant: What Are the Best Options for Mothers and Neonates? by Annemarie Unger, Verena Metz, Gabriele Fischer

“…Pregnancy in opioid-dependent women is a major public health issue. …”
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A Comprehensive Analysis of Fibromyalgia and the Role of the Endogenous Opioid System by Mario García-Domínguez

“…One explanation for the emergence of disrupted pain modulation in individuals with fibromyalgia is a significant reduction in opioid receptor activity or an imbalance in the levels of endogenous opioid peptides. …”
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Influence of opioid peptides on human neutrophil apoptosis and activation in vitro by Zofia Sulowska, Ewa Majewska, Katarzyna Krawczyk, Magdalena Klink, Henryk Tchórzewski

“…Background: It has been shown that cells of the immune system release opioid peptides and possess receptors for them. The concentrations of opioid peptides in the peripheral circulation rapidly increase during inflammation and acute stress response.…”
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Health information-seeking on Reddit, by people who use opioids by Margaret Sullivan, Jonah Hancock, George Shaw, Chaoqun Ni

“…People who use opioids need more information on harm reduction strategies, and especially safely administering and withdrawing from them.…”
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Chronic Use of Opioids for Nonmalignant pain: A Prospective Study by Perry N Fuchs, Ann Gamsa

“…OBJECTIVE: To assess the effects of long term opioid therapy on pain, mood, and social and leisure activities in patients with chronic nonmalignant pain.…”
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Disparities in Opioid Use Disorder Treatment Admissions in the United States by Peter J. Mallow, Michael Mercado, Michael Topmiller

“…**Objectives:** The Cincinnati region has been at the epicenter of the nation’s unfolding opioid epidemic. The objectives of this study were twofold: (1) to compare the Cincinnati region to the United States in length of time to obtain treatment and planned medication-assisted therapy for the treatment for opioid use disorder (OUD); and (2) to assess racial disparities within the Cincinnati region in wait time and type of treatment. …”
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Serotonin circuits act cooperatively with pathophysiology of opioid use disorder by Arakawa Hiroyuki, Ozawa Akihiko

Subjects: “…Opioid receptors…”
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Naming the sites of the opioid crisis in Boston: a political issue by Elsa Vivant

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Effects of Gabapentin on Pain and Opioid Consumption after Abdominal Hysterectomy by Fatemeh Frouzanfard, Mohammed Reza Fazel, Azadeh Abolhasani, Esmaeil Fakharian, Golmabas Mousavi, Alireza Moravveji

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Buprenorphine for Chronic Pain: A Safer Alternative to Traditional Opioids by Suhani Dalal, Ahish Chitneni, Amnon A. Berger, Vwaire Orhurhu, Bilal Dar, Bennett Kramer, Anvinh Nguyen, John Pruit, Charles Halsted, Alan D. Kaye, Jamal Hasoon

“…Buprenorphine is a partial mu-opioid agonist which is commonly utilized to treat patients with opioid-use disorders. …”
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Association between different modalities of opioid use disorder-related care delivery and opioid use disorder-related patient outcomes: A retrospective cohort study by Nahiyan Bin Noor, George Pro, Mahip Acharya, Hari Eswaran, Corey J. Hayes

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Hospital and physician-based mental healthcare during 12 months of opioid agonist treatment for opioid use disorder: Exploring costs and factors associated with acute care. by Tea Rosic, Glenda Babe, Myanca Rodrigues, Brittany B Dennis, Richard Perez, Claire de Oliveira, Andrew Worster, Lehana Thabane, Zainab Samaan

“…<h4>Background</h4>Individuals with opioid use disorder (OUD) have a high prevalence of co-occurring mental health disorders; however, there exists little information on mental health service use for this population. …”
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Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study protocol by A Eden Evins, Ellie Grossman, Julia Jashinski, Aurora Quaye, Corinne Cather, Kevin Potter, David A Schoenfeld, Jodi M Gilman

“…Introduction Chronic, non-cancer pain impacts approximately 50 million adults in the USA (20%), approximately 25% of whom receive chronic prescription opioids for pain despite limited empirical efficacy data and strong dose-related risk for opioid use disorder and opioid overdose. …”
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Is It Still Prohibited to Perform Spinal Anesthesia in Patients with Advanced Heart Disease? by Maryam Vosoughian, Shide Dabir, Faramarz Mosaffa

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Pain catastrophizing is associated with high-dose opioids in patients with cancer pain by Simon van Rysewyk, Melanie Lovell, Paul Glare

“…At referral, most patients were on strong opioids, with many on high doses (>100 mg oral morphine equivalents (OME) per day). …”
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