Continuous adductor canal block versus continuous femoral nerve block for postoperative pain in patients undergoing knee arthroplasty: An updated meta-analysis of randomized contro... by Jinyan Gong, Lu Tang, Yuyu Han, Pengcheng Liu, Xue Yu, Fei Wang

“…In addition, there was no significant difference in opioid consumption, knee extension and flexion, timed up and go (TUG) test, or risk of falls between the two groups. …”
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Acute pain pathways: protocol for a prospective cohort study by Christine Lee, Joseph S Ross, Molly Moore Jeffery, Nilay D Shah, David B Page, Nancy Chang, Fernanda Bellolio, Sam Torbati, Jessica D Ritchie, Gregg H Gilbert, Lindsay Emanuel, Mitra Ahadpour, Summer Allen, Richardae Araojo, Laura Ciaccio, Jonathan Fillmore, Patricia Koussis, Heather Lipkind, Celeste Mallama, Tamra Meyer, Megan Moncur, Teryl Nuckols, Michael A Pacanowski, Elektra Papadopoulos, Mat Soukup, Christopher O St. Clair, Stephen Tamang, Douglas W Wallace, Yueqin Zhao, Rebekah Heckmann

“…Introduction Opioid analgesics are often used to treat moderate-to-severe acute non-cancer pain; however, there is little high-quality evidence to guide clinician prescribing. …”
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A Contribution to the Understanding of Pain in Fibromyalgia Based on Cerebrospinal Fluid Investigations by Henning Værøy

“…Chemical changes in the cerebrospinal fluid are of interest and seem to show significant relationships with fibromyalgia, both with respect to opioid peptides and substance P. The nature of these relationships and their possible linkage with neuronal plasticity at the spinal cord level are discussed. …”
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Cocktail of Ropivacaine, Morphine, and Diprospan Reduces Pain and Prolongs Analgesic Effects after Total Knee Arthroplasty: A Prospective Randomized Controlled Trial by Zhenyu Luo, Weinan Zeng, Xi Chen, Qiang Xiao, Anjing Chen, Jiali Chen, Haoyang Wang, Zongke Zhou

“…The primary outcomes were the levels of inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6), pain visual analog scale (VAS) scores, opioid consumption, range of motion (ROM), functional tests, and sleeping quality. …”
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A randomized controlled study of auricular point acupressure to manage chemotherapy-induced neuropathy: Study protocol. by Nada Lukkahatai, Michael V Nguyen, Jingyu Zhang, Yu-Min Cho, Chitchanok Benjasirisan, Heijingzi Monica Jia, Claudia M Campbell, Jennifer Kawi, Hulin Wu, Hongyu Wang, Rupsikha Bora, Johannes Thrul, Constance M Johnson, Thomas J Smith

“…<h4>Objective</h4>Chemotherapy-induced neuropathy (CIN) significantly impacts cancer patients, leading to functional disability, diminished quality of life, and increased healthcare costs amid the ongoing opioid crisis. Auricular point acupressure (APA), a non-invasive and non-pharmacological alternative, has shown potential for alleviating the pain, numbness, and tingling associated with CIN. …”
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The relative risk of fatal poisoning by methadone or buprenorphine within the wider population of England and Wales by Dave Marteau, Rebecca McDonald, Kamlesh Patel

“…Objective To examine the population-wide overdose risk emerging from the prescription of methadone and buprenorphine for opioid substitution treatment in England and Wales.Design Retrospective administrative data study.Setting National databases for England and Wales.Participants/cases Drug-related mortality data were drawn from the Office for National Statistics, and prescription data for methadone and buprenorphine were obtained from the National Health Service for the years 2007–2012. …”
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Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study by Gezahegn Tesfaye Mekonin, Megersa Kelbesa Olika, Mitiku Birhanu Wedajo, Ashanafi Tolasa Badada, Abebe Dukessa Dubiwak, Tajera Tageza Ilala, Mamo Nigatu Gebre

“…The prevalence of emergence delirium was high among older patients who underwent elective surgery. Opioid and anticholinergic premedication, low preoperative hemoglobin, and the presence of postoperative pain were independently associated with the emergence delirium. …”
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The Effect of Intraoperative Methadone Compared to Morphine on Postsurgical Pain: A Meta-Analysis of Randomized Controlled Trials by Mark C. Kendall, Lucas J. Alves, Kristi Pence, Taif Mukhdomi, Daniel Croxford, Gildasio S. De Oliveira

“…The aggregated effect of intraoperative methadone on postoperative opioid consumption did not reveal a significant effect, WMD (95% CI) of −0.51 (−1.79 to 0.76), (P=0.43) IV morphine equivalents. …”
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Alcohol, alcoholism and related consequences by M. V. Mayevskaya

“…Opioid receptors are involved in development of alcohol-induced dependency. …”
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Health care utilization patterns of patients enrolled in an interdisciplinary program for back pain by Sara Davin, Psy.D., MPH, Brittany Lapin, PhD., MPH, Belinda Udeh, PhD, Sarah Rispinto, PhD, Nicolas R. Thompson, MS, Ryan Honomichl, PhD, Andre Machado, MD, Irene L. Katzan, MD

“…Healthcare utilization categories included outpatient resources, specialist visits, imaging, pain interventional procedures, and acute care utilization. Opioid use was also extracted based on inpatient and outpatient orders, as well as days on opioids within 2 weeks following an emergency department visit or hospitalization. …”
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Comparison of Transcutaneous Electrical Nerve Stimulation and Parasternal Block for Postoperative Pain Management after Cardiac Surgery by Nilgun Kavrut Ozturk, Elif Dogan Baki, Ali Sait Kavakli, Ayca Sultan Sahin, Raif Umut Ayoglu, Arzu Karaveli, Mustafa Emmiler, Kerem Inanoglu, Bilge Karsli

“…Parasternal block and transcutaneous electrical nerve stimulation (TENS) have been demonstrated to produce effective analgesia and reduce postoperative opioid requirements in patients undergoing cardiac surgery. …”
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Costoclavicular block as a diaphragm-sparing nerve block for shoulder surgery: a randomized controlled trial by Youngin Lee, Seunguk Bang, Jihyun Chung, Min Suk Chae, Jungwon Shin

“…Diaphragmatic excursion, pulmonary function test results, opioid consumption, and pain scores were evaluated. …”
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Robotic Assistance in Unicompartmental Knee Arthroplasty Results in Superior Early Functional Recovery and Is More Likely to Meet Patient Expectations by Meredith P. Crizer, Amer Haffar, Andrew Battenberg, Mikayla McGrath, Ryan Sutton, Jess H. Lonner

“…No differences were reported with respect to postoperative opioid usage p=0.320, reoperations p=1.00, and complications p=0.628. …”
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Efficacy and safety of perioperative analgesia in PENG block for children undergoing hip surgery with developmental dysplasia: study protocol for a randomized, double-blinded, non-... by Mingzhe Xu, Yi He, Zhi Li, Bin Du

“…Perioperative analgesia, usually based on high opioid dosages, is frequently used in these patients. …”
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Potential improvement in spatial accessibility of methadone treatment with integration into other outpatient substance use disorder treatment programs, New York City, 2024. by Marcus A Bachhuber, Chinazo O Cunningham, Ashly E Jordan

“…<h4>Background</h4>Methadone is an effective treatment for opioid use disorder; however, its provision in the US is limited to federally-regulated opioid treatment programs (OTP). …”
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Efficacy of Acupuncture Combined with Patient-Controlled Analgesia in the Treatment of Acute Pain after Back Surgery: A Meta-Analysis by Daling Deng, Feng Xu, Yafeng Wang, Lulin Ma, Tianhao Zhang, Wenjing Zhao, Xiangdong Chen

“…Acupuncture + PCA decreased the use of opioids after surgery compared to sham acupuncture + PCA (SMD = −0.35, 95% CI = ‒0.63 to ‒0.07, P=0.01) or control group (SMD = ‒0.82, 95% CI = ‒1.03 to ‒0.61, P<0.01). …”
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Study on the Analgesic Efficacy of Femoral Nerve Block for Post-Hip Arthroscopy Pain by Mengwen Xue, Li Zhang, Ruiping Bai, Rui An, Jiarui Li, Xin Shen

“…The IAI group had greater intraoperative opioid consumption and more side effects. Conclusions Compared with IAI anesthesia, FNB can better alleviate post-hip arthroscopy pain and reduce opioid consumption. …”
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An Interactive Pain Application (MServ) Improves Postoperative Pain Management by Richard Gordon-Williams, Andreia Trigo, Paul Bassett, Amanda Williams, Stephen Cone, Martin Lees, Brigitta Brandner

“…Most patients have moderate or severe pain after surgery. Opioids are the cornerstone of treating severe pain after surgery but cause problems when continued long after discharge. …”
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Impact of Exercise on Tramadol-Conditioned Place Preference by Haneen Amawi, Alaa M. Hammad, Aseel Abdullah Ibrahim, Nosyba Alsbih, Frank Scott Hall, Fawaz Alasmari, Bahaa Al-Trad

“…Background: Tramadol (TRA) is an opioid that is used to manage moderate to severe pain. …”
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Postoperative Pain and Opiate Requirement is Increased Following Second-Side Surgery Among Patients Undergoing Staged Total Knee Arthroplasty by Vivek P. Chadayammuri, MD, Shuvalaxmi D. Haselton, MS, Elizabeth Diaz, PA-C, Roger H. Emerson, MD

“…Patients with a history of chronic opioid dependency were excluded. Baseline demographics, primary outcome measures, including visual analog scale (VAS) pain scores, perioperative opioid utilization (MME/day), and surgical satisfaction were evaluated. …”
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