Identification of mitophagy-related biomarkers and immune infiltration in polycystic ovarian syndrome by bioinformatic study by Hongjuan Ye, Xicheng Wang, Zhiying He

“…GRN and NAPA were validated to be significantly different in oocytes and granulosa cells between primary and secondary follicles, respectively. …”
Get full text

The piRNA protein Asz1 is essential for germ cell and gonad development in zebrafish and exhibits differential necessities in distinct types of germ granules. by Adam Ahmad, Yoel Bogoch, Gal Shvaizer, Noga Guler, Karine Levy, Yaniv M Elkouby

“…Germline development requires distinct types of germ granules, which contains RNA-protein (RNP) complexes, including germ plasm in embryos, piRNA granules in gonadal germ cells, and the Balbiani body (Bb) in oocytes. However, the regulation of RNP assemblies in zebrafish germline development are still poorly understood. …”
Get full text

How do lifestyle and environmental factors influence the sperm epigenome? Effects on sperm fertilising ability, embryo development, and offspring health by Ayazhan Akhatova, Celine Jones, Kevin Coward, Marc Yeste

“…DNA methylation is correlated with alterations in sperm quality and the ability to fertilise oocytes, possibly via a differentially regulated MAKP81IP3 signalling pathway. …”
Get full text

Gengnianchun Recipe Protects Ovarian Reserve of Rats Treated by 4-Vinylcyclohexene Diepoxide via the AKT Pathway by Fangui Zhao, Wenjun Wang

“…Diminished ovarian reserve (DOR) refers to a decrease in the number and quality of oocytes. Western treatment of DOR does not improve the ovarian reserve fundamentally, and the effect is limited. …”
Get full text

The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

“…The main outcome measures were, firstly, to follow up plasma levels of interleukin (IL) 1beta, IL2, IL4, IL5, IL6, IL8, IL10, IL17, interferon gamma, tumor necrosis factor-alpha (TNFα), transforming growth factor-beta (TGFβ), regulated upon activation normal T-cell expressed and secreted (RANTES), stromal cell-derived factor 1 alpha (SDF1α), and decidual granulocyte-macrophage colony-stimulating factor (GM-CSF) during the three trimesters of pregnancy during the three trimesters of pregnancy; secondly, to evaluate if the cytokine and chemokine pattern of ED pregnant women differs from that of those with autologous oocytes and, thirdly, to assess if women with preeclampsia show different cytokine and chemokine profile throughout pregnancy versus women with uneventful pregnancies. …”
Get full text

Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries by Yi-Ping Zhong, Ying Ying, Hai-Tao Wu, Can-Quan Zhou, Yan-Wen Xu, Qiong Wang, Jie Li, Xiao-Ting Shen, Jin Li

“…The ovulatory PCO and PCOS patients showed similar levels of E2 on the human chorionic gonadotropin treatment day and numbers of oocytes, which were both significantly higher than those of the NO patients. …”
Get full text

Generation of live mice from haploid ESCs with germline-DMR deletions or switch by Yongjian Ma, Meng Yan, Zhenfei Xie, Hongling Zhang, Zhoujie Li, Yuanyuan Li, Suming Yang, Meiling Zhang, Wen Li, Jinsong Li

“…Moreover, embryos reconstructed by injection of AG-haESCs with hypomethylated H19-DMR into oocytes with H19-DMR deletion develop into live mice sustaining inverted allelic gene expression. …”
Get full text

CRISPR/Cas9-editing of PRNP in Alpine goats by Aurélie Allais-Bonnet, Christophe Richard, Marjolaine André, Valérie Gelin, Marie-Christine Deloche, Aurore Lamadon, Gwendoline Morin, Béatrice Mandon-Pépin, Eugénie Canon, Dominique Thépot, Johann Laubier, Katayoun Moazami-Goudarzi, Ludivine Laffont, Olivier Dubois, Thierry Fassier, Patrice Congar, Olivier Lasserre, Tiphaine Aguirre-Lavin, Jean-Luc Vilotte, Eric Pailhoux

“…Genome editors were injected under the zona pellucida prior to the electroporation of 565 Alpine goat embryos/oocytes. A total of 122 two-cell-stage embryos were transferred to 46 hormonally synchronized recipient goats. …”
Get full text

Mapping of Minimal Motifs of B-Cell Epitopes on Human Zona Pellucida Glycoprotein-3 by Wan-Xiang Xu, Ya-Ping He, Jian Wang, Hai-Ping Tang, Hui-Juan Shi, Xiao-Xi Sun, Chao-Neng Ji, Shao-Hua Gu, Yi Xie

“…Furthermore, the antigenicity of two peptides for hZP3172–187 and hZP3301–315 and specificity of the antibody response to these peptides were also evaluated, which produced high-titer antibodies in immunized animals that were capable of reacting to ZP on human oocytes, r-hZP3b177–348 protein, as well as r-hZP3172–190, r-hZP3303–310, and r-hZP3313–320 epitope peptides fused with truncated GST188 protein.…”
Get full text

Sperm DNA fragmentation index: limited effectiveness on predicting embryo quality in assisted reproduction technology treatments by Huan Jiang, Xiaolu Xia, Ying Luo, Haiyan Pan, Shihao Qu, Jianying Xu

“…Male factors (age, BMI, DFI, infertility duration, sperm parameters) and female parameters (age, BMI, AMH, retrieved oocytes) were evaluated. We also assessed embryological parameters like fertilization rate, cleavage rate, and blastocyst quality. …”
Get full text

The Effect of Maternal Body Mass Index on in Vitro Fertilization-Intracytoplasmic Sperm Injection Treatment: A Prospective Comparative Study by Zeynep Ozturk Inal, Hasan Ali Inal

“…In addition, the numbers of oocytes retrieved (groups 1 vs 3, p=0.011), metaphase II (groups 1 vs 3, p=0.017) and 2 pronucleus (groups 1 vs 3, p=0.010 and groups 2 vs 3, p=0.010), and the rates of clinical pregnancy (40.1% vs 33.2% vs 23.8%, respectively), live births (33.6% vs 23.7% vs 13.9%, respectively), and miscarriages (17.7% vs 28.6% vs 44.7%, respectively) were also different between the groups (p<0.05). …”
Get full text

Risk factors associated with pregnancy loss after single euploid blastocysts transfer by Xiaohui Dong, Juanzi Shi, Xiaohua Liu, Danmeng Liu, Wei Li, Xiaoli Zhao, Xia Xue

“…Compared to the live birth group, the PL group had lower E2 levels (2376.03 ± 1553.25 vs 3412.88 ± 2116.47, P=0.007), higher LH levels (2.66 ± 2.47 vs 1.96 ± 1.52, P=0.023) on trigger day of fresh cycle, fewer retrieved oocytes (10.08 ± 5.01 vs 12.77 ± 7.20, P=0.044), higher female BMI (23.26 ± 3.27 vs 22.05 ± 2.69, P=0.016), higher proportion of maternal smokers (50% vs 20.51%, P&lt;0.001), and more day 6 blastocyst transfers ((38.89% vs14.53, P=0.001). …”
Get full text

Nomogram to predict cumulative live birth rate following in vitro fertilization/intracytoplasmic sperm injection cycles in patients with endometriosis by Linling Zhu, Tongtong Lin, Xinyun Yang, Dan Zhang

“…Higher numbers of fertilized oocytes and high-quality embryos were associated with an increased likelihood of CLB. …”
Get full text

Synapsis and recombination of autosomes and sex chromosomes in two terns (Sternidae, Charadriiformes, Aves) by A. P. Lisachov, L. P. Malinovskaya, A. V. Druzyaka, P. M. Borodin, A. A. Torgasheva

“…We used immunolocalization of SYCP3, the protein of the lateral element of the synaptonemal complex (SC), centromere proteins and the mismatch-repair protein MLH1, which is associated with the recombination nodules, at the synaptonemal complex spreads of prophase oocytes of two tern species, black tern (Chlidonias niger) and common tern (Sterna hirundo). …”
Get full text

Sero-epidemiological Study of Toxoplasma gondii among Pregnant Women in Akre City by Hogir Mohammed Shukri Saadi, Ahmed Jumaa Ahmed

“…Many previous studies were suggested this pathogen transmits by ingesting of undercooked or raw meat contaminated with the oocytes of this parasite. The study aimed to show the seroreactivity of Toxoplasma gondii antibodies among pregnant women and to evaluate association of studied risk factors with infected cases. …”
Get full text

Factors Influencing the Pregnancy Outcome of Intrauterine Insemination and Follow-Up Treatment by Xuan Huang, Qin Sun, Xu Tang, Meiling Li, Cheng Zhou, Xi Cheng, Bing Yao, Li Chen

“…However, there were no differences between the pregnant group and the non-pregnant group amongst the female and male age, BMI, hormones on baseline and day of human chorionic gonadotrophin, number of ovulated oocytes, sperm parameters before and after wash, treatment protocols and the timing of IUI (P > 0.05). …”
Get full text

Cohort profile: Anhui Maternal–Child Health Study in China by Yunxia Cao, Ruoling Chen, Weiju Zhou, Xiaofeng Xu, Xiaoqing Peng, Jiaqian Yin, Chunmei Liang, Ranjit Khutan, Fang-Biao Tao

“…Details of their children’s health are documented through a questionnaire focusing on developmental status and anthropometry measurement.Findings to date Until April 2021, AMCHS had recruited 2042 couples in the study. 111 women withdrew from the study and 19 failed to retrieve oocytes. Among the 1475 confirmed pregnancies, 146 had miscarriages or terminated their pregnancies, 9 had stillbirths and 263 were ongoing pregnancies. …”
Get full text

Comparison of live birth rate and fetal outcomes between fresh embryo and frozen-thawed embryo transfers: a prospective study by Seyedeh Farinaz Fattahpour, Parvin Hakimi, Fatemeh Tabatabaei, Mahsa Hejazad, Maryam Amoozadeh, Leila Sadeghi, Negin Rezaie, Razih Vejdani, Hosein Azizi

“…The number of retrieved oocytes was significantly higher in frozen ET compared to fresh ET (P = 0.001). …”
Get full text

The Assessment of Different Dietary Selenium Resources on Reproductive Performance, Spawning Indicators, and Larval Production of Red Tilapia (Oreochromis mossambicus × O. niloticu... by Mohammed A. E. Naiel, El-Sayed H. Eissa, Yasmin M. Abd El-Aziz, Saadea Saadony, Heba E. Abd Elnabi, Salah El-Sayed Sakr

“…The fish group fed NPSe alone or mixed with Na2SeO3 had a well-developed stroma structure, many mature vitellogenic and postvitellogenic oocytes, and a remarkable intensity of mature spermatozoa in the testis. …”
Get full text

Optimal dietary vitamin E level facilitates ovarian development of female largemouth bass (Micropterus salmoides) broodstock by Qiuyu Gao, Qiao Feng, Dong Zhou, Zhili Ding, Changle Qi, Youqin Kong, Qiyou Xu

“…Meanwhile, it was observed that a predominant number of ovarian cells in fish fed 209.31 and 437.77 mg/kg of vitamin E had advanced to maturation, primarily consisting of mature oocytes at stage IV and V. Dietary vitamin E supplementation significantly upregulated the expression of genes involving vitamin E transfer, ovarian development, and hormone, including alpha-tocopherol transfer protein, luteinizing hormone, follicle-stimulating hormone, vitellogenin receptor (vgr), vitellogenin (vg), 17-beta-hydroxysteroid dehydrogenase (17β-hsd), cyclin-dependent kinase 2 (cdk2), and cytochrome P450 family 17 (cyp-17), with the highest expression levels detected in the 209.31 mg/kg group (P < 0.05). …”
Get full text