CLINICAL CARE PATHWAY AND MANAGEMENT OF MAJOR BLEEDING ASSOCIATED WITH NON-VITAMIN K ANTAGONIST ORAL ANTICOAGULANTS: A MODIFIED DELPHI CONSENSUS FROM SAUDI ARABIA AND UAE by Abdulrahman Al Raizah, Fakhr Alayoubi, Galal Hassan Abdelnaby, Hazzaa Alzahrani, Majid Farraj Bakheet, Mohammed A Alskaini, Rasha Buhumaid, Sameer Al Awadhi, Sara Nooruddin Kazim, Thiagarajan Jaiganesh, Zohair Al Asiri

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Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency by Boonchai Boonyawat, Tim Phetthong, Nithipun Suksumek, Chanchai Traivaree

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Host genetics and gut microbiota influence lipid metabolism and inflammation: potential implications for ALS pathophysiology in SOD1G93A mice by Elena Niccolai, Leandro Di Gloria, Maria Chiara Trolese, Paola Fabbrizio, Simone Baldi, Giulia Nannini, Cassandra Margotta, Claudia Nastasi, Matteo Ramazzotti, Gianluca Bartolucci, Caterina Bendotti, Giovanni Nardo, Amedeo Amedei

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Advancing precision medicine: the transformative role of artificial intelligence in immunogenomics, radiomics, and pathomics for biomarker discovery and immunotherapy optimization by Luchen Chang, Jiamei Liu, Jialin Zhu, Shuyue Guo, Yao Wang, Zhiwei Zhou, Xi Wei

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Long-term Prospective Comparative Analysis of Ototoxic and Survival Outcomes of Sequential Boost and Simultaneous Integrated Boost of Volumetric Modulated Arc Therapy for Head-Neck... by Nidhin Das, Sri Harsha Kombathula, Vidhu Sharma, Puneet Pareek, Kapil Soni, Amit Goyal

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Ultrasound outcomes and surgical parameters of the double-layer purse-string uterine closure technique in cesarean delivery: a systematic review and meta-analysis of randomized tri... by Mahsan Nabighadim, Maryam Vaezi, Mahsa Maghalian, Mojgan Mirghafourvand

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Adjuvant Therapy after Esophagectomy for Esophageal Cancer: Who Needs It?: Multi-institution Worldwide Observational Study by Siva Raja, MD, PhD, Thomas W. Rice, MD, Min Lu, PhD, Marie E. Semple, MPH, Andrew J. Toth, MS, Eugene H. Blackstone, MD, Sudish C. Murthy, MD, PhD, Usman Ahmad, MD, Michael McNamara, MD, Hemant Ishwaran, PhD, for the Worldwide Esophageal Cancer Collaboration Investigators

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Construction and function validation of inducible immortalized gene integration vectors by YUE Wei, YANG Yue, QIAN Baohua, LI Yanxin, GU Haihui

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USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression by Shaoxuan Cheng, Zhiyuan Qiu, Ziyi Zhang, Yuxuan Li, Yue Zhu, Yuxin Zhou, Yinghui Yang, Yaowen Zhang, Dian Yang, Yingqiu Zhang, Han Liu, Zhaoxia Dai, Shu-Lan Sun, Shuyan Liu

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Early Changes in [18F]FDG Uptake as a Readout for PI3K/Akt/mTOR Targeted Drugs in HER-2-Positive Cancer Xenografts by Yanina Dockx, Christel Vangestel, Tim Van den Wyngaert, Manon Huizing, Sven De Bruycker, Patrick Pauwels, Steven Staelens, Sigrid Stroobants

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Polygenic height prediction for the Han Chinese in Taiwan by Chih-Hao Chang, Che-Yu Chou, Timothy G. Raben, Shih-Ann Chen, Yuh-Jyh Jong, Jeng-Yih Wu, Shun-Fa Yang, Hsiang-Cheng Chen, Yen-Lin Chen, Ming Chen, Gwo-Chin Ma, Chih-Yang Huang, Tso-Fu Wang, Sing-Lian Lee, Chen-Fang Hung, See-Tong Pang, Erik Widen, Yao-Ming Chang, Erh-Chan Yeh, Chun-Yu Wei, Chien-Hsiun Chen, Stephen D. H. Hsu, Pui-Yan Kwok

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Global, regional and national burdens of cardiovascular disease attributable to secondhand smoke from 1990–2019: an age-period-cohort analysis by Hong Jiang, Xiang-Bin Pan, Xiaofei Li, Shouzheng Wang, Zeye Liu, Peijian Wei, Fengwen Zhang, Wen-Bin Ou-yang

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Immunogenicity in humans of a transdermal multipeptide melanoma vaccine administered with or without a TLR7 agonist by Craig L Slingluff, Gina R Petroni, Walter C Olson, Kimberly A Chianese-bullock, Donna Deacon, Mark Smolkin, William W Grosh, Max O Meneveau, Kevin T Lynch, Elise P Salerno, Elizabeth Woodson, James W Patterson

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The Role of Dectin-1-Akt-RNF146 Pathway in β-Glucan Induced Immune Trained State of Monocyte in Sepsis by Guo C, Xu P, Luo W, Zhang J, Sun X, Hoang H, Ma D, Wu D, Zhong J, Miao C

“…Chenyue Guo,1,* Peiyao Xu,1,* Wenchen Luo,1,* Jinlin Zhang,1,* Xingfeng Sun,2 Harry Hoang,3 Duan Ma,4 Dehua Wu,5 Jing Zhong,1 Changhong Miao1 1Department of Anesthesiology, Zhongshan Hospital Fudan University, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, People’s Republic of China; 2Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of China; 3Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; 4Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, Collaborative Innovation Center of Genetics and Development, Institute of Biomedical Sciences, School of Basic Medical Sciences, Fudan University, Shanghai, People’s Republic of China; 5Department of Anesthesiology, Shanghai Songjiang District Central Hospital, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Changhong Miao; Jing Zhong, Email ziteng1934@aliyun.com; jzhong12@fudan.edu.cnBackground: Sepsis is regarded as a dysregulated immune response to infections. …”
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The clinical impact of conventional therapies for adults and adolescents suffering from eosinophilic esophagitis, a type 2 inflammatory chronic disease, and their economic conseque... by Giorgio Walter Canonica, MD, Gherardo Mazziotti, MD, PhD, Alessandro Repici, MD, Massimiliano Povero, PhD, Luca Castello, MSc, Lorenzo Pradelli, MD, Miryana Dobreva, MSc, Francesca Fanelli, MSc, Jean Pierre Saab, MD, Edoardo Vincenzo Savarino, MD, PhD

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Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients by Kai Bartkowiak, Parinaz Mossahebi Mohammadi, Paula Nissen, Stefan Werner, David Agorku, Antje Andreas, Maria Geffken, Sven Peine, Karl Verpoort, Thomas M. Deutsch, Laura L. Michel, Andreas Schneeweiss, Verena Thewes, Andreas Trumpp, Olaf Hardt, Volkmar Müller, Sabine Riethdorf, Hartmut Schlüter, Klaus Pantel

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Biosynthesis of Lysosomally Escaped Apoptotic Bodies Inhibits Inflammasome Synthesis in Macrophages by Jiayi Mao, Wenzheng Xia, Yanglin Wu, Minxiong Li, Yun Zhao, Peisong Zhai, Yuguang Zhang, Tao Zan, Wenguo Cui, Xiaoming Sun

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Network Meta-Analysis and Trial Sequential Analysis of Randomised Controlled Trials Comparing Robotic, Laparoscopic, and Open Pancreatoduodenectomy by Nejo Joseph, MBChB, Chris Varghese, MBChB, James Lucocq, MBChB, Matthew J. McGuinness, MBChB, Samuel Tingle, MBChB, Giovanni Marchegiani, PhD, Kjetil Soreide, PhD, Mohammed Abu-Hilal, Jas Samra, Marc Besselink, PhD, Steve White, Sanjay Pandanaboyana, FRCS

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PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53 by Yongli Fan, Yuqin Li, Xia Luo, Shiqi Xiang, Jia Hu, Jingchun Zhan, Weilong Chang, Rui Deng, Xianwen Ran, Yize Zhang, Yudie Cai, Weiwei Zhu, Huifen Wang, Zhibo Liu, Di Wang

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Integrative analysis of cuproptosis-related lncRNAs: Unveiling prognostic significance, immune microenvironment, and copper-induced mechanisms in prostate cancer by Haitao Zhong, Yiming Lai, Wenhao Ouyang, Yunfang Yu, Yongxin Wu, Xinxin He, Lexiang Zeng, Xueen Qiu, Peixian Chen, Lingfeng Li, Jie Zhou, Tianlong Luo, Hai Huang

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