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    Causal Association Between Skin Microbiota and Malignant Melanoma: Genetic Insights From Mendelian Randomization by Li X, Wu S, Pan Y, Wu Z, Du Z, Xie W, Zhou Q

    Published 2025-01-01
    “…Xianglong Li,1 Shuang Wu,2 Yujie Pan,3 Ziyan Wu,3 Zhong Du,1 Wanying Xie,1 Qingyu Zhou1 1Department of Medical and Radiation Oncology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Critical Care, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 3School of Medicine, Yichun University, Yichun, People’s Republic of ChinaCorrespondence: Qingyu Zhou, Email zqy17@foxmail.comBackground: Malignant melanoma (MM) is an extremely aggressive type of skin cancer that represents a major risk to human health. …”
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    Impact of the SARS-CoV-2/COVID-19 pandemic on the patient journeys of those with a newly diagnosed paediatric brain tumour in the UK: a qualitative study by Rachel Isba, Donald MacArthur, Liz Brewster, Ibrahim Jalloh, John-Paul Kilday, Kalsoom Akhter, Roland Casson, G A Amos Burke

    Published 2025-01-01
    “…Objectives To explore the impact of the SARS-CoV-2/COVID-19 pandemic on the diagnosis, management and patient journey for children and young people with a newly diagnosed brain tumour in the UK.Design Exploratory qualitative study focused on patient journeys from multiple perspectives, conducted as part of a wider mixed-methods study.Setting Three paediatric oncology tertiary centres in the UK.Participants 10 children and young people with brain tumours (n=6 females, n=4 males), 20 caregivers (n=16 females, n=4 males) and 16 stakeholders (specialist nurses, consultant neurosurgeons and oncologists, and representatives from brain tumour charities) were interviewed between January 2022 and June 2023.Results The paper incorporates multiple perspectives, including those of children and young people, parents/caregivers, clinical staff and charity representatives, to explore the patient journey. …”
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