Immune Microenvironment in Colorectal Cancer: A New Hallmark to Change Old Paradigms by Luis de la Cruz-Merino, Fernando Henao Carrasco, David Vicente Baz, Esteban Nogales Fernández, Juan José Reina Zoilo, Manuel Codes Manuel de Villena, Enrique Grande Pulido

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Secondary Hemophagocytic Syndrome: The Importance of Clinical Suspicion by Cristina Oliveira, Sérgio Chacim, Isabel Ferreira, Nelson Domingues, José Mário Mariz

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The Use of Etoposide, Ara-Cytarabine, and Melphalan (EAM) Conditioning Chemotherapy in Autologous Stem Cell Transplantation (ASCT) for a Patient with Relapsed Hodgkin’s Lymphoma by Eko A. Pangarsa, Ridho M. Naibaho, Vina Yunarvika, Budi Setiawan, Damai Santosa, Catharina Suharti

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A Case Delayed Hemorrhage from the Stump of the Superior Rectal Artery after Abdominoperineal Resection of the Rectum by Yuichi Sanada, Kenichi Nonaka, Takao Takahashi, Yoshihiro Tanaka, Shinji Osada, Kazuhiro Yoshida

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Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma by Nieves Gascón, Héctor Pérez-Montero, Sandra Guardado, Rafael D’Ambrosi, María Ángeles Cabeza, José Fermín Pérez-Regadera

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Mayor Erythropoietic Response after Deferasirox Treatment in a Transfusion-Dependent Anemic Patient with Primary Myelofibrosis by Del Corso Lisette, Balleari Enrico, Arboscello Eleonora, Ghio Riccardo, Mencoboni Manlio, Racchi Omar

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Tumor metabolic regulators: key drivers of metabolic reprogramming and the promising targets in cancer therapy by Kun Huang, Ying Han, Yihong Chen, Hong Shen, Shan Zeng, Changjing Cai

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Modern Prospection for Hepatic Arterial Infusion Chemotherapy in Malignancies with Liver Metastases by Yi-Hsin Liang, Yu-Yun Shao, Jia-Yi Chen, Po-Chin Liang, Ann-Lii Cheng, Zhong-Zhe Lin

“…Malignancy with liver metastasis plays an important role in daily oncology practice, especially for primary cancers of the gastrointestinal tract and hepatopancreatobiliary system. …”
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Solid Predominant Histology and High Podoplanin Expression in Cancer-Associated Fibroblast Predict Primary Resistance to Osimertinib in EGFR-Mutated Lung Adenocarcinoma by Yuji Uehara, MD, Hiroki Izumi, MD, PhD, Tetsuro Taki, MD, PhD, Tetsuya Sakai, MD, PhD, Hibiki Udagawa, MD, PhD, Eri Sugiyama, MD, PhD, Shigeki Umemura, MD, PhD, Yoshitaka Zenke, MD, PhD, Shingo Matsumoto, MD, PhD, Kiyotaka Yoh, MD, PhD, Shoko Kubota, MD, PhD, Keiju Aokage, MD, PhD, Naoya Sakamoto, MD, PhD, Shingo Sakashita, MD, PhD, Motohiro Kojima, MD, PhD, Michiko Nagamine, MD, PhD, Yukio Hosomi, MD, PhD, Masahiro Tsuboi, MD, PhD, Koichi Goto, MD, PhD, Genichiro Ishii, MD, PhD

“…We also investigated HGF mRNA expression levels, using The Cancer Genome Atlas Program and Singapore Oncology Data Portal cohorts. Results: The study included 93 patients. …”
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INTRAPERITONEAL AEROSOL CHEMOTHERAPY UNDER PRESSURE (IACUP) – AN INNOVATIVE METHOD OF TREATMENT OF PATIENTS WITH PERITONEAL CARCINOMATOSIS by A. D. Kaprin, V. M. Khomyakov, A. B. Ryabov, L. V. Bolotina, A. V. Ivanov, A. B. Utkina, V. V. Cheremisov, I. V. Kolobaev, A. V. Chaika, D. D. Sobolev, L. A. Koroleva

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Perioperative pembrolizumab in early-stage non-small cell lung cancer (NSCLC): safety, efficacy, and exploratory biomarker analysis by Jeff Clarke, Xiaofei Wang, Thomas Stinchcombe, Scott J Antonia, Jeffrey Crawford, Neal Ready, Konstantin H Dragnev, Lin Gu, Cameron Wood, James M Isaacs, Liliana Lyniv, Kent Weinhold, Jacob M Kaufman, Eziafa I Oduah, Betty C Tong, Dennis Wigle

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Effect of primary tumor volume on survival of concurrent chemoradiotherapy in stage IV non‐small cell lung cancer by Xiaxia Chen, Wei Zhang, Lan Luo, Shimei Fu, Dongdong Cao, Shengfa Su, Qingsong Li, Wengang Yang, Yichao Geng, Bing Lu, Weiwei Ouyang

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A meta-analysis of the value of indocyanine green fluorescence imaging in guiding surgical resection of primary and metastatic liver cancer by Dali Xiong, Jiaran Li, Li Li, Fuhao Xu, Tao Hu, He Zhu, Xiaohui Xu, Yawen Sun, Shuanghu Yuan

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Commentary: Sodium levels and immunotherapy efficacy in mRCC patients with bone metastases: sub analysis of the Meet-Uro 15 study by Martina Catalano, Sara Elena Rebuzzi, Giuseppe Fornarini, Giandomenico Roviello

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The Oxidative Stress Response Gene P66SHC and the Tumor Suppressor Gene P53 Induce Mitochondrial Dna Damages by Mirella Trinei, Marco Giorgio, Sara Barozzi, Pier Giuseppe Pelicci

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Multiple Intraosseous Calvarial Hemangiomas Mimicking Metastasis from Renal Cell Carcinoma by Rohit Malde, Tim Moss, George Malcolm, Tim Whittlestone, Amit Bahl

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MODERN TREATMENT OF METASTATIC MELANOMA: FROM STANDARDS TO AN INDIVIDUALIZED APPROACH IN REAL CLINICAL PRACTICE by N. V. Zhukova, R. V. Orlova, N. Yu. Antimonik, S. I. Kutukova, N. P. Belyak, N. V. Popova, S. P. Erdniev

“…Petersburg Regional Clinical Hospital “City Clinical Oncology Clinic” in the treatment of patients with metastatic melanoma under the conditions of real clinical practice with the preparation of ipilimumab as part of the expanded access program from February 2014 to March 2017. …”
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Fusobacterium nucleatum promotes colorectal cancer liver metastasis via miR-5692a/IL-8 axis by inducing epithelial-mesenchymal transition by Yulong Yu, Han Yin, Bili Wu, Weiheng Zhao, Yuan Wang, Aifeina Aili, Mu Yang, Qianqian Yu, Xianglin Yuan

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Adjuvant treatments for locally advanced differentiated thyroid cancer: a nationwide survey in Japan by Terufumi Kawamoto, Koichi Yasuda, Yoshinori Ito, Sadamoto Zenda, Katsuyuki Sakanaka, Naoto Shikama, Naoki Nakamura, Takashi Mizowaki

“…A survey on treatment selection criteria for hypothetical locally advanced DTC was administered to representative thyroid surgeons of facilities participating in the Japan Clinical Oncology Group Radiation Therapy Study Group. Of the 43 invited facilities, surgeons from 39 (91%) completed the survey. …”
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Effect of diabetes mellitus on levels of insulin-like growth factors and their carrier proteins in Guerin’s carcinoma and it’s perifocal tissue in rats by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, N. D. Cheryarina, P. S. Kachesova, L. A. Nemashkalova

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