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Key oncogenes and candidate drugs for hepatitis-B-driven hepatocellular carcinoma progression
Published 2025-02-01Get full text
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Oncogene-tumor suppressor gene feedback interactions and their control
Published 2015-07-01Subjects: Get full text
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Helicobacter pylori Oncogenicity: Mechanism, Prevention, and Risk Factors
Published 2020-01-01Get full text
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Roles of Oncogenic Long Non-coding RNAs in Cancer Development
Published 2018-12-01Subjects: Get full text
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Oncogenic processes: a neglected parameter in the evolutionary ecology of animals
Published 2024-11-01Get full text
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Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use
Published 2025-01-01Get full text
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Epigenetic and epitranscriptomic regulation during oncogenic γ-herpesvirus infection
Published 2025-01-01“…The resultant reprogramming can lead to activation of oncogenes, silencing of tumor suppressor genes, and evasion of the immune response, which ultimately contributes to the oncogenic potential of these viruses. …”
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Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors
Published 2014-01-01“…The oncogenic transcription factor FOXM1 is one of the key regulators of tumorigenesis. …”
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Oncogenic mutant KRAS inhibition through oxidation at cysteine 118
Published 2025-02-01Subjects: Get full text
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Radiogenomics and machine learning predict oncogenic signaling pathways in glioblastoma
Published 2025-01-01“…Conclusion We present a novel approach for the non-invasive prediction of deregulation in oncogenic signaling pathways in glioblastoma (GBM) by integrating radiogenomic data with machine learning models. …”
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The Role of the PAX8/PPARγ Fusion Oncogene in Thyroid Cancer
Published 2008-01-01“…The PAX8/PPARγ fusion gene appears to be an oncogene. It is most often expressed in follicular carcinomas and exerts a dominant-negative effect on wild-type PPARγ, and stimulates transcription of PAX8-responsive promoters. …”
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Oncogenic PIK3CA corrupts growth factor signaling specificity
Published 2024-12-01“…Using this framework, we found that the PIK3CA H1047R oncogene was not a simple, constitutive activator of the pathway as often presented. …”
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S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling
Published 2017-01-01Get full text
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The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction
Published 2017-01-01“…The loss of oncogene addiction in SCN-adapted LSC has a consequence of crucial practical relevance: the refractoriness to inhibitors of the biological activity of oncogenic protein due to the lack of their molecular target. …”
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Viral mimicry evasion: a new role for oncogenic KRAS mutations
Published 2025-02-01“…In a recent study, Zhou and colleagues identify KRAS, a frequently mutated oncogene, as a negative regulator of dsRNA and viral mimicry in an ICI‐resistant colorectal cancer model. …”
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Impact of R-loops on oncogene-induced replication stress in cancer cells
Published 2023-09-01Subjects: Get full text
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Oncogenic RIT1 mutations confer ferroptosis vulnerability in lung adenocarcinoma
Published 2025-02-01Subjects: Get full text
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