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341
Biomarkers of inflammation and colorectal cancer risk
Published 2025-02-01“…In terms of screening, non-invasive methods like fecal occult blood tests (FOBTs) are widely used, and combining biomarkers with iFOBT shows potential. Multi-omics techniques, including genomics and microbiomics, offer new avenues for CRC diagnosis. …”
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342
High antimony resistance strain Enterobacter sp. Z1 mediates biomineralization of antimony trioxide
Published 2025-01-01“…Z1 produced antimony trioxide (Sb2O3) via biomineralization during cultivation. Omics analysis revealed the upregulation of pyruvate metabolism and accumulation of DL-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) in the presence of Sb(III).Using pyruvate as the sole carbon source in a chemically defined medium significantly enhanced Sb(III) biomineralization ratio from 20.8 % to 90.4 % compared with that using R2A medium. …”
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343
Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles
Published 2025-01-01“…NP coronas alter cell associations in a disease-dependent manner, induce differential co-stimulatory and co-inhibitory molecule expression, and influence cytokine release. Integrated multi-omics analysis of proteomics, lipidomics, metabolomics, and cytokine datasets highlight a set of differentially enriched TLR4 ligands that correlate with dynamic NP corona-mediated immune activation. …”
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344
Soil Alveolata diversity in the undisturbed steppe and wheat agrocenoses under different tillage
Published 2023-11-01“…The ITS-metabarcoding technique was used for the first time in the research of ciliates diversity; further studies, embracing diverse aspects of soil ciliates by combining -omics methodology with the traditional one, are needed to get a better insight on the ecological roles of the main ciliate taxa in the complex soil system.…”
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345
Tissue-resident immune cells: from defining characteristics to roles in diseases
Published 2025-01-01“…The advancement of tissue-resolution technologies, such as single-cell sequencing and spatiotemporal omics, provides deeper insights into the cell morphology, characteristic markers, and dynamic transcriptional profiles of TRICs. …”
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346
A review on bioremediation by microbial immobilization-an effective alternative for wastewater treatment
Published 2024-10-01“…The potential integration of 'omics' technologies for enhancing and revealing new insights into bioremediation via cell immobilization is also discussed.…”
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347
Machine learning techniques for predicting neurodevelopmental impairments in premature infants: a systematic review
Published 2025-01-01“…Furthermore, the inclusion of omics data as a contemporary approach employed, in other diagnostic contexts is proposed.ConclusionsWe identified limitations and emphasized the significance of employing multimodal data models and explored various alternatives to address the limitations identified in the reviewed studies. …”
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348
Removing limitations surrounding terpenoid biosynthesis by biotechnological techniques in Ferula sp.: A review
Published 2025-03-01“…Recently, via functional genomics, omics technologies, and high-throughput analytical techniques, our understanding about terpenoid biosynthesis and regulation has been deepened, paving the way for the overproduction of target terpenoids. …”
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349
Protocol for correlating the gut microbiome and metabolomics in patients with intracranial aneurysms
Published 2025-03-01“…Finally, we perform combined multi-omics analysis.For complete details on the use and execution of this protocol, please refer to Xu et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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350
Block-Constraint Laplacian-Regularized Low-Rank Representation and Its Application for Cancer Sample Clustering Based on Integrated TCGA Data
Published 2020-01-01“…With the breakthrough of “OMics” technology, many LRR-based methods have been proposed and used to cancer clustering based on gene expression data. …”
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351
Expression and clinical significance of disulfidptosis-related LncRNA in gastric cancer
Published 2024-09-01“…Objective To construct prognostic model of disulfidptosis-related LncRNA (DRLncs) and explore the mechanism of LncRNA-small nucleolar RNA host genes(SNHG4) in promoting the progression of gastric cancer. Methods The multi-omics features of disulfidptosis genes in gastric cancer were first analyzed based on The Cancer Genome Atlas(TCGA) database. …”
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352
Tailoring microbial redox with alternating current for efficient mineralization of refractory organic nitrogen compounds in wastewater
Published 2025-01-01“…AC stimulation enhances biofilm formation and bidirectional electrocatalytic activity, leading to higher biomass and electron utilization efficiency. Multi-omics analysis shows enrichment of functional microbial consortia involved in NB reduction, aromatic compound oxidation, ammonia oxidation, nitrate/nitrite reduction, and electron transfer, with upregulated enzyme gene expression. …”
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353
The technology landscape for detection of DNA methylation in cancer liquid biopsies
Published 2025-12-01“…Lastly, we believe that multi-omics technologies, which can combine diverse types of biomarkers, will most likely become more important in future clinical applications. …”
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354
SLC2A5 Correlated with Immune Infiltration: A Candidate Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma
Published 2021-01-01“…Finally, we used the LinkedOmics database to evaluate the SLC2A5-related coexpression and functional networks in LUAD and to investigate their role in tumor immunity. …”
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355
Roles of fermented plant-, dairy- and meat-based foods in the modulation of allergic responses
Published 2023-05-01Get full text
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356
Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in Rafflesiaceae
Published 2025-01-01“…In this study, we use homology-based in silico approaches to characterize micro-RNAs (miRNAs) expressed by Sapria himalayana and Rafflesia cantleyi from published omics data. Derived from secondary structures or hairpins, miRNAs are small regulators of gene expression. …”
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357
Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach
Published 2017-01-01“…Metabolomics is an emerging “omics” technology in systems biology study which integrated in process of discovering drug from natural products. …”
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A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment
Published 2024-11-01“…Investigators further highlighted the importance of omics technologies in understanding the regulation and biosynthesis of SMs, which offers an understanding of novel applications in drug discovery and sustainable agriculture. …”
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