Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…Implementation of clinical guidelines can promote improvement of healthcare quality for GERD patients and prevent complications, in particular if terms of treatment will be observed, at active outpatient follow­up for certain groups of patients.…”
Get full text

Polimorfisme Gen Apolipoprotein E Pada Penderita Sindrom Down Trisomi 21 by Malinda Meinapuri

“…Methods : This is a case control study to observe the difference of distribution and frequency of APOE gene allele and genotype in Down Syndrome Trysomi 21 compared to control. …”
Get full text

Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis by Alisha Puri, Anita M. Lloyd, Aminu K. Bello, Marcello Tonelli, Sandra M. Campbell, Karthik Tennankore, Sara N. Davison, Stephanie Thompson

“…Selection Criteria for Studies: Observational studies and randomized trials. Data Extraction: Risk and precision measurements; measurement properties. …”
Get full text

Enhancing reproductive capacity in hybrid Red Tilapia (Oreochromis niloticus ×‎ O. mossambicus) via dietary administration of date palm pollen (Phoenix dactylifera L.)‎ by Nashi K. Alqahtani, Hesham S. Ghazzawy, Roshmon Thomas Mathew, Yousef‎ Ahmed Alkhamis, Rashid Saleh Alngada, Moaheda E.H. Eissa, Sameh A. Abdelnour, Sara F. Ghanem, Layla A. Almutairi, El-Sayed Hemdan Eissa

“…The lowest values for these parameters were observed in the DPP40 group. Lipase activity was significantly improved by DPP dietary inclusion, while amylase activity remained unaffected (P > 0.05). …”
Get full text

Perbedaan Rerata Kadar Profil Lipid pada Preeklampsia dengan Kehamilan Normal pada Etnik Minangkabau by Helen Evelina Siringoringo, Yusrawati ., Eva Chundrayetti Chundrayetti

“…The objective of this study was to find out the difference of lipid profile mean level in preeclampsia and normal pregnancy at Minangkabau Ethnic. This was an observational study with cross-sectional design at  dr. …”
Get full text

Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

“…Meanwhile, Wahlengergia androsacea A.DC exhibited the most significant (p < 0.05) CYP3A4 inhibitory effect at the same concentration in intestinal microsomes. Conclusion: The observed inhibitory effects of certain wild edible plants on P-gp-mediated drug efflux and CYP3A4 drug metabolism indicate potential food/herb-drug interactions challenges for clinical practice. …”
Get full text

Most prevalent jobs of young master’s degree graduates by detailed field of study by Marc Frenette, Tomasz Handler

“…While there are plenty of noteworthy results in the tables, the remainder of this article will simply highlight a few key observations. Readers are invited to examine the results based on their specific interests. …”
Get full text

The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…Eight groups were tested for 28 days in the animal dissection laboratory of the Faculty of Agriculture of Birjand University, observing all ethical considerations. This study aimed to determine the synergistic effect of garlic and turmeric extracts for possible protection against injury induced by aflatoxin B1 (AFB1). …”
Get full text

Comparison of long-term ankle joint function after one-stage and staged microsurgical repair of open achilles tendon defects by Jianjie Mao, Yang Xiang, Hui Chu, GenYang Jin, Guangyan Su, Chang zeng Liu, Feng Zhu

“…In the second stage, 31 patients underwent flexor hallucis longus tendon transfer, and 35 patients underwent peroneus longus muscle tendon transfer with the lateral calcaneal artery. Observations included evaluation of the continuity and healing of the Achilles tendon via colour Doppler ultrasound 3 months postoperatively and assessment of ankle joint function 2 years postoperatively using the American Orthopedic Foot and Ankle Society ankle–hindfoot score (AOFAS) and the Achilles tendon total rupture score (ATRS). …”
Get full text

Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases by Orsolya Anna Simon, Levente Frim, Nelli Farkas, Zoltán Sipos, Nóra Vörhendi, Eszter Boros, Dániel Pálinkás, Brigitta Teutsch, Patrícia Kalló, Vivien Vass, Andrea Szentesi, Roland Hágendorn, Péter Hegyi, Bálint Erőss, Imre Szabó

“…Numerous primary (in-hospital mortality, discharge, need for endoscopic intervention, in-hospital rebleeding, length of hospitalisation, need for emergency surgery, need for endoscopic examination and need for intensive care unit) and secondary (detection of Helicobacter pylori (H. pylori), recognition of cancer as the source of bleeding, need for any kind of transfusion or clotting factor, anticoagulation therapy) outcomes were observed. Descriptive statistical tools were used to summarize our data. …”
Get full text

Algunas aplicaciones recientes de la técnica de radio ocultamiento satelital en el estudio de procesos atmosféricos by Alejandro de la Torre, Pedro Alexander, Pablo Llamedo, Rodrigo Hierro, Horacio Pessano, Andres Odiard

“…Se pondrá especial énfasis sobre las regiones montañosas de la cordillera de los Andes a latitudes medias y de la península antártica, para lo cual se analizarán individualmente eventos de RO de interés, a partir de las excepcionales características observables de OIG en dicha región. Dicho análisis será complementado con simulaciones numéricas con el modelo de mesoescala WRF, versión 3.2. y con perfiles de T de RO disponibles en las regiones de interés. …”
Get full text

Forest fire hazard assessment based on forest typology by Volodymyr P. Voron, Andriy D. Kuzyk, Sergiy V. Ivashyniuta, Yilia R. Tsipan

“…The greatest representation of fire-prone species was observed in dry pine forests (A1), where out of 11 species, 8 have a high inflammability. …”
Get full text

Le voisinage entre hommes, forêt et les chimpanzés : point de vue depuis le territoire des villageois, à l’extérieur du Parc National de Kibale by Sarah Bortolamiol, Marianne Cohen, Andrew Seguya, Richard Dumez, Sabrina Krief

“…Nous avons combiné des entretiens semi-directifs et des observations participantes (N = 42 villageois et agriculteurs, gestionnaires, employés des usines de thé) avec des relevés floristiques en lisière de forêt (N = 8 transects soit 32 relevés situés entre 0 et 150 mètres de part et d’autre de la lisière de la forêt – janvier à avril 2013) dans un Système d’Information Géographique (SIG) pour spatialiser les rapports entre les hommes que nous avons interrogés et les chimpanzés que nous étudions. …”
Get full text

Prevalence and Antimicrobial Susceptibility of Bacterial Uropathogens Isolated from Pediatric Patients at Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia by Yamirot Merga Duffa, Kumera Terfa Kitila, Dereje Mamuye Gebretsadik, Adane Bitew

“…Multidrug resistance to two or more drugs was observed in 73.7% of the bacterial isolates. Conclusion. …”
Get full text

Designing a security-oriented leadership model of Mazandaran University of Medical Sciences by Saeid Miladigorji, Mohammad Hassan Shakki, Mojtaba Rezaei Rad

“…Based on the presented model, the central category, along with causal factors, has been observed to be effective in the security-oriented leadership model of Mazandaran University of Medical Sciences. …”
Get full text

Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis by Roberto Buonaiuto, Aldo Caltavituro, Margherita Tafuro, Alessandra Longobardi, Giuliana Pavone, Pierluigi De Santis, Roberta Caputo, Carmine De Angelis, Lucia Del Mastro, Fabio Puglisi, Mario Giuliano, Grazia Arpino, Martina Pagliuca, Michelino De Laurentiis

“…Interestingly, a numerically higher rate of treatment-related hematological toxicity was observed in Asian patients, although no significant interethnic difference was found in the relative risk of these events. …”
Get full text

The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Conclusions: Our study found that taVNS treatment did not induce adverse cardiovascular effects, such as bradycardia or QT prolongation, supporting its development as a safe immunomodulatory treatment approach for SAH patients. The observed acute increase in heart rate after taVNS treatment may serve as a biomarker for SAH patients who could derive greater benefit from this treatment. …”
Get full text

Implementing a nurse-enabled, integrated, shared-care model involving specialists and general practitioners in early breast cancer post-treatment follow-up (EMINENT): a single-cent... by Raymond J. Chan, Fiona Crawford-Williams, Chad Yixian Han, Lee Jones, Alexandre Chan, Daniel McKavanagh, Marissa Ryan, Christine Carrington, Rebecca L. Packer, Megan Crichton, Nicolas H. Hart, Emma McKinnell, Melissa Gosper, Juanita Ryan, Bethany Crowe, Ria Joseph, Carolyn Ee, Jane Lee, Steven M. McPhail, Katharine Cuff, Laisa Teleni, Jon Emery

“…No differences were observed between groups for health-related quality of life and the other effectiveness outcomes measures listed above at all timepoints (P > 0.05 for all). …”
Get full text

Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections by Emily Lydon, Christina M. Osborne, Brandie D. Wagner, Lilliam Ambroggio, J. Kirk Harris, Ron Reeder, Todd C. Carpenter, Aline B. Maddux, Matthew K. Leroue, Nadir Yehya, Joseph L. DeRisi, Mark W. Hall, Athena F. Zuppa, Joseph Carcillo, Kathleen Meert, Anil Sapru, Murray M. Pollack, Patrick McQuillen, Daniel A. Notterman, Charles R. Langelier, Peter M. Mourani

“…In bacterial coinfection, we observed increases in the TNF-stimulated protein TSG-6, as well as CRP, and interferon-related proteins. …”
Get full text

Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts by Kelley Weinfurtner, David Tischfield, George McClung, Jennifer Crainic, John Gordan, Jing Jiao, Emma E. Furth, Wuyan Li, Erena Tuzneen Supan, Gregory J. Nadolski, Stephen J. Hunt, David E. Kaplan, Terence P.F. Gade

“…No differences were observed in tumor engraftment or growth latency in subcutaneous tumors, but orthotopic tumors required implantation at 2 rather than 4 weeks post-humanization for successful engraftment. …”
Get full text