Expression of Leptin Receptor and Effects of Leptin on Papillary Thyroid Carcinoma Cells by Marilena Celano, Valentina Maggisano, Saverio Massimo Lepore, Marialuisa Sponziello, Valeria Pecce, Antonella Verrienti, Cosimo Durante, Marianna Maranghi, Piernatale Lucia, Stefania Bulotta, Giuseppe Damante, Diego Russo

“…Background. Obesity has been hypothesized to contribute to the aggressiveness of thyroid cancer through the production of abnormal levels of serum adipokines. …”
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Pre-diagnostic risk factors for brain cancer incidence and survival: insights from the Golestan Cohort Study by Parisa Rezanejad-Asl, Peyvand Parhizkar Roudsari, Negar Rezaei, Maryam Sharafkhah, Gholamreza Roshandel, Hossein Poustchi, Sadaf Sepanlou, Reza Malekzadeh

“…In the multiple model, Turkmen ethnicity (Hazard Ratio = 0.42 (0.23–0.76)), urban residence (HR = 0.46 (0.25–0.84)), overweight or obesity (HR = 0.48 (0.25–0.93)), and history of animal contact (HR = 0.43 (0.19–0.96)) were associated with a better survival. …”
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Clinicopathological characteristics and survival outcomes of women aged ≤45 and >45 years with endometrial adenocarcinoma in tertiary referral hospital: a 21-year cohort study by Tarinee Manchana, Pinyada Panyavaranant, Juthamas Rattanachaipipat

“…Among the population, 188 patients (16.9%) were ≤45 years old and 926 patients (83.1%) were >45 years old.Outcome measures The primary outcome measures were disease-free survival (DFS) and overall survival (OS) at 5, 10 and 15 years, with an analysis of survival rates based on patient age groups and prognostic factors.Results Younger patients (≤45 years) displayed significantly higher rates of obesity, nulliparity and polycystic ovary syndrome (PCOS), as well as favourable pathological characteristics such as well-differentiated tumours and lower rates of myometrial invasion. …”
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Targeted microbiome metabolomics reveals flaxseed oil supplementation regulated the gut microbiota and farnesoid X receptor pathway in high-fat diet mice by Chen Yang, Zhenxia Xu, Qingde Huang, Xu Wang, Fenghong Huang, Qianchun Deng

“…Flaxseed oil (FSO) rich in n-3 polyunsaturated fatty acids (PUFAs) can protect against obesity and insulin resistance, but the underlying mechanism is unknown. …”
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Healthcare utilization and related costs among older people seeking primary care due to back pain: findings from the BACE-N cohort study by Danielle van der Windt, Milada Cvancarova Småstuen, Kjersti Storheim, Margreth Grotle, Zinajda Zolic-Karlsson, Ørjan Nesse Vigdal, Rikke Munk Killingmo, Lise Kretz

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Early Left Ventricular Systolic and Diastolic Dysfunction in Patients with Newly Diagnosed Obstructive Sleep Apnoea and Normal Left Ventricular Ejection Fraction by Lisulov Popovic Danica, Mirjana Krotin, Marija Zdravkovic, Ivan Soldatovic, Darko Zdravkovic, Milica Brajkovic, Vera Gardijan, Jelena Saric, Ruzica Pokrajac, Dragan Lovic, Predrag Stevanovic, Milina Tancic Gajic, Miodrag Vukcevic

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Interaction effect between vitamin D and gestational diabetes mellitus in the second trimester by MA Ziwen, DING Xiaoying, CHU Liming, ZHANG Yan, ZHANG Aifeng, ZHU Yanjun, WANG Xun, XIE Zhenyu

“…Serum 25(OH)D was non-linearly correlated with the risk of GDM in an inverted J-shape, and there was an interaction effect of advanced age, pre-pregnancy obesity and vitamin D deficiency on the risk of GDM.ConclusionVitamin D is non-linearly associated with the risk of GDM. …”
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Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses by Ye Ma, Fang Wu, Zeming Yu, Lu Yang

“…Furthermore, it was determined that the causal associations between these lipidome profiles and FRDs were independent of BMI, obesity, diabetes, smoking, alcohol use, physical activity, inflammation, depression, waist-hip ratio, vitamin D, dehydroepiandrosterone sulphate, sex hormone binding globulin, and testosterone levels. …”
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International expert consensus on micronutrient supplement use during the early life course by Irene Cetin, Roland Devlieger, Erika Isolauri, Rima Obeid, Francesca Parisi, Stefan Pilz, Lenie van Rossem, Maternal Nutrition Delphi Study Group, Régine Steegers-Theunissen

“…There was also consensus that supplement use advice should be tailored for people following vegan/vegetarian diets, restricted diets due to food intolerances, obesity, polycystic ovary syndrome, diabetes mellitus, and previous nutrition-related pregnancy complications. …”
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Association between serum uric acid levels and left ventricular hypertrophy based on electrocardiographic findings: a sex-specific analysis across cardiometabolic diseases by Anwar Ahmed Salim, Shin Kawasoe, Takuro Kubozono, Satoko Ojima, Satoshi Yamaguchi, Koji Higuchi, Yoshiyuki Ikeda, Hironori Miyahara, Koichi Tokushige, Mitsuru Ohishi

“…Furthermore, UA was associated with LVH in individuals without obesity, dyslipidemia, reduced kidney function, and diabetes in both sexes. …”
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Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis by Bin You, Bin You, Bin You, Bin You, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen

“…Subgroup analyses did not reveal statistically significant interactions by age, sex, or obesity status, although associations appeared stronger in younger adolescents.ConclusionElevated blood manganese and selenium levels are associated with a higher prevalence of hepatic steatosis in adolescents. …”
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The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages by Hui juan Zhu, Su juan Li, Hui Pan, Naishi Li, Dian xi Zhang, Lin jie Wang, Hong bo Yang, Qinyong Wu, Feng ying Gong

“…In conclusion, kisspeptin levels were firstly found to be notably changed in pubertal stages and nutritional status in Chinese children and adolescents with a significant sexual dimorphism. Obese/overweight girls had higher kisspeptin levels, and there was a positive correlation between kisspeptin and FSH and LH and obesity-related parameters in all boys and girls.…”
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Effects of a high-fat diet on the lipid profile of oocytes in mice by E. Yu. Brusentsev, E. A. Chuyko, K. A. Okotrub, T. N. Igonina, I. N. Rozhkova, D. S. Ragaeva, S. V. Ranneva, V. A. Naprimerov, S. Ya. Amstislavsky

“…There are evidences that obese women exhibit a detrimental oocyte quality. …”
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Association between Metformin and a Lower Risk of Age-Related Macular Degeneration in Patients with Type 2 Diabetes by Yu-Yen Chen, Ying-Cheng Shen, Yun-Ju Lai, Chun-Yuan Wang, Keng-Hung Lin, Shih-Chao Feng, Chiao-Ying Liang, Li-Chen Wei, Pesus Chou

“…Confounders included for adjustment were age, sex, and comorbidities (hypertension, hyperlipidemia, coronary artery disease, obesity, diabetic retinopathy, chronic kidney disease, and insulin treatment). …”
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The Transcultural Diabetes Nutrition Algorithm: A Canadian Perspective by Réjeanne Gougeon, John L. Sievenpiper, David Jenkins, Jean-François Yale, Rhonda Bell, Jean-Pierre Després, Thomas P. P. Ransom, Kathryn Camelon, John Dupre, Cyril Kendall, Refaat A. Hegazi, Albert Marchetti, Osama Hamdy, Jeffrey I. Mechanick

“…The Canadian version of tDNA supports and targets behavioural changes to improve nutritional quality and to promote regular daily physical activity consistent with Canadian Diabetes Association CPG, as well as channelling the concomitant management of obesity, hypertension, dyslipidemia, and dysglycaemia in primary care. …”
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Social inequalities in the use of online food delivery services and associations with weight status: cross-sectional analysis of survey and consumer data by Jean Adams, Martin White, Frank de Vocht, Emma Boyland, Steven Cummins, Laura Cornelsen, Amy Yau, Thomas Burgoine, Cherry Law, Alexandra Irene Kalbus

“…While takeaway food delivery app use was positively associated with living with obesity (relative risk ratio 1.84, 95% CI 1.20 to 2.82), use of online grocery delivery services was not.Discussion Findings indicate that use of online food delivery services is patterned by markers of social position and weight status, which may lead to dietary inequalities. …”
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Cardiac CT reveals high prevalence of coronary artery disease in esophageal cancer eligible for radiotherapy by Akinori Takada, Satoshi Nakamura, Yutaka Toyomasu, Takamitsu Mase, Tomoko Kawamura, Suguru Araki, Yoshitaka Suzuki, Masaki Ohi, Hajime Sakuma, Yoshihito Nomoto, Kakuya Kitagawa

“…Specifically, esophageal cancer and heart disease share common risk factors, such as smoking and obesity. Radiation therapy (RT) for esophageal cancer is associated with elevated cardiac radiation exposure. …”
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Clustering of non-communicable disease risk factors among school teachers: A cross-sectional study in Kerala, India by Mini GK, Sangeeth KS, Anand Marthanda Pillai, Sarma PS, Thankappan KR

“…Results: The main risk factors were physical inactivity (76.4 %) and overweight/obesity (68.8 %). Current tobacco use was reported by 5 % of men, while 13.4 % of men and 2.6 % of women reported alcohol use. …”
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The synergistic role of gut microbiota and RNA in metabolic diseases: mechanisms and therapeutic insights by Zhuo Huang, Zhuo Huang, Qinyan Yao, Qinyan Yao, Shuang Ma, Shuang Ma, Jinjie Zhou, Jinjie Zhou, Xiaoxuan Wang, Xiaoxuan Wang, Qingguo Meng, Qingguo Meng, Yaxin Liu, Yaxin Liu, Zihan Yu, Zihan Yu, Xin Chen, Xin Chen

“…Dysbiosis of the gut microbiota has been linked to metabolic disorders such as type 2 diabetes, obesity, metabolic-associated fatty liver disease (MAFLD) and metabolic heart disease. …”
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Prediction of implant failure risk due to periprosthetic femoral fracture after primary elective total hip arthroplasty: a simplified and validated model based on 154,519 total hip... by M. A. Alagha, Justin Cobb, Alexander D. Liddle, Henrik Malchau, Ola Rolfson, Maziar Mohaddes

“…Predictive factors for revision and reoperation were identified, with patient features such as increasing age, higher American Society of Anesthesiologists grade (> III), and World Health Organization obesity classes II to III associated with elevated risks. …”
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