Impact of HACOR Score on Noninvasive Ventilation Failure in Non-COPD Patients with Acute-on-Chronic Respiratory Failure by Min Ding, Xiaoli Han, Linfu Bai, Shicong Huang, Jun Duan

“…A total of 148 patients were enrolled in the study, 52 with sleep apnea-hypopnea syndrome, 34 with chronic thoracic sequelae, 31 with bronchiectasis, 14 with chest wall deformity, 5 with obesity-hypoventilation syndrome, and 12 with other conditions. …”
Get full text

Identification of Interactive Genetic Loci Linked to Insulin Resistance in Metabolic Syndrome—An Update by Imadeldin Elfaki, Rashid Mir, Mohamed E. Elnageeb, Abdullah Hamadi, Zeyad M. Alharbi, Ruqaiah I. Bedaiwi, Jamsheed Javid, Tariq Alrasheed, Dalal Alatawi, Basmah M. Alrohaf, Mohammed K. Abunab, Turki Ahmed Muqri

“…Metabolic syndrome is a metabolic disorder characterized by hypertension, dyslipidemia, impaired glucose tolerance, and abdominal obesity. Impaired insulin action or insulin resistance initiates metabolic syndrome. …”
Get full text

Unveiling the role of lncRNA ERDR1 in immune cell regulation by Aihua Shu, Xu Tian, Jie Yue, Yuxia Jiang, Yifei Liu

“…Furthermore, Erdr1 has been implicated in the mitigation of several diseases, including acne, wound healing, osteoarthritis, melanoma, gastric cancer, obesity, and autism. Given its complex biological functions and mechanisms, Erdr1 presents itself as a promising biomarker and a potential therapeutic target for a range of immune cell-related disorders.…”
Get full text

Relationship between physical activity during pregnancy and maternal health outcomes: evidence from the MAASTHI cohort study in Bengaluru, India by Yamuna Ana, Floor A. van den Brand, Onno C. P. van Schayck, Giridhara R. Babu

“…In addition, women who engaged in sedentary behavior during pregnancy were 1.07 times more likely to be obese and 4.32 times more likely to have elective cesarean section (C-section) delivery than those who engaged in moderate activity.ConclusionThe study found that physical activity during pregnancy has several beneficial effects on maternal prenatal health outcomes, including a reduced risk of obesity and C-section delivery, lower blood glucose levels, and improved mental health. …”
Get full text

An mHealth Intervention With Financial Incentives to Promote Smoking Cessation and Physical Activity Among Black Adults: Protocol for a Feasibility Randomized Controlled Trial by Adam Alexander, Michael Businelle, Marshall Cheney, Amy Cohn, Lorna McNeill, Kevin Short, Summer Frank-Pearce, David Bradley, Kimberly Estrada, Iván Flores, Jack Fronheiser, Darla Kendzor

“… BackgroundBlack adults in the United States experience disproportionately high rates of tobacco- and obesity-related diseases, driven in part by disparities in smoking cessation and physical activity. …”
Get full text

Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages by Hiroki Yamazaki, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Yusuke Nakatsu, Takako Kikuchi, Sunao Kaneko, Hirotoshi Tanaka, Tomoichiro Asano

“…Sex hormone-binding globulin (SHBG) is a serum protein released mainly by the liver, and a low serum level correlates with a risk for metabolic syndrome including diabetes, obesity, and cardiovascular events. However, the underlying molecular mechanism(s) linking SHBG and metabolic syndrome remains unknown. …”
Get full text

TrkB Receptor Antagonism Enhances Insulin Secretion and Increases Pancreatic Islet Size in Rats Fed a Cafeteria-Style Diet by Jorge Agustín Velasco-Gutierrez, Elena Roces de Alvarez-Buylla, Sergio Montero, Alejandrina Rodríguez-Hernández, Saraí Limón Miranda, Karmina Martínez-Santillan, María del Rosario Álvarez-Valadez, Mónica Lemus, Alejandra Flores-Silva, Adolfo Virgen-Ortiz

“…<b>Conclusions:</b> Under conditions of cafeteria-style diet-induced obesity, the antagonism of the BDNF-trkB pathway had no enhanced effect on the increase in insulin secretion or pancreatic islet size.…”
Get full text

Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma by Kazuhito Oba, Yuko Chiba, Yoko Matsuda, Takeshi Kumakawa, Rie Aoyama, Miho Akahoshi, Seiji Hashimoto, Aya Tachibana, Koichi Toyoshima, Remi Kodera, Kenji Toyoshima, Yoshiaki Tamura, Takashi Nagata, Yuto Yamazaki, Hironobu Sasano, Atsushi Araki

“…A 47-year-old woman with a history of diabetes mellitus (DM) and obesity was admitted to our hospital for glucose control. …”
Get full text

Association Between Allometric Body Shape Indices and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study from NHANES by Zhao S, Pan X

“…Songfeng Zhao,1,2 Xin Pan1,2 1Department of Endocrinology, The First People’s Hospital of Xiaoshan District, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Endocrinology, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Xin Pan, Department of Endocrinology, The First People’s Hospital of Xiaoshan District, No. 199 South Shixin Road, Xiaoshan District, Hangzhou, Zhejiang, People’s Republic of China, Tel +86-0571-83807971, Email 344132702@qq.comBackground: Osteoporosis is a common health concern in postmenopausal women. Obesity, commonly assessed using body mass index (BMI), may have a protective effect on osteoporosis in postmenopausal women. …”
Get full text

Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis by Cristina Gonzalez-Martin, Silvia Grande Morais, Sonia Pertega-Diaz, Teresa Seoane-Pillado, Vanesa Balboa-Barreiro, Raquel Veiga-Seijo

“…The most prevalent risk factors were overweight and obesity, followed by smoking and hypertension. The prevalence of patients with moderate/high cardiovascular risk varies according to the score used, the levels of concordance being the scores of Framingham and Dorica.…”
Get full text

Global, regional, and national burdens of type 1 and type 2 diabetes mellitus in adolescents from 1990 to 2021, with forecasts to 2030: a systematic analysis of the global burden o... by Xing Chen, Luying Zhang, Wen Chen

“…Moreover, more efforts are needed to control climate change and obesity to reduce the adolescent diabetes burden.…”
Get full text

Serum Fibroblast Growth Factor 21 Levels Are Positively Associated with Metabolic Syndrome in Patients with Type 2 Diabetes by Ruo-Yao Gao, Bang-Gee Hsu, Du-An Wu, Jia-Sian Hou, Ming-Chun Chen

“…Serum FGF21 levels were significantly higher in obesity and type 2 diabetes mellitus (T2DM) populations. …”
Get full text

Reducing personal protective equipment waste in the emergency department of a large regional hospital: codesign informed by system science by Mike Forrester, Rebecca Patrick, Steven Allender, Jaithri Ananthapavan, Urvi Thanekar, Hasini Gunasiri, Minoo Naebe, Maryam Naebe

Get full text

Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease by Emmanouil Nychas, Andrea Marfil-Sánchez, Xiuqiang Chen, Mohammad Mirhakkak, Huating Li, Weiping Jia, Aimin Xu, Henrik Bjørn Nielsen, Max Nieuwdorp, Rohit Loomba, Yueqiong Ni, Gianni Panagiotou

“…Results Here, we collected public metagenomic data and integrated the taxonomy profiles with in silico generated community metabolic outputs, and detailed clinical data, of 1206 Chinese subjects w/wo metabolic diseases, including NAFLD (obese and lean), obesity, T2D, hypertension, and atherosclerosis. …”
Get full text

Prevalence of non-alcoholic fatty liver disease in out-patients of the Russian Federation: DIREG 2 study results by V. T. Ivashkin, O. M. Drapkina, I. V. Mayev, A. S. Trukhmanov, D. V. Blinov, L. K. Palgova, V. V. Tsukanov, T. I. Ushakova

“…The high prevalence of NANCFLD was revealed in primary or secondary patients admitted healthcare institutions for any reason including those with suspected NAFLD (patients with obesity, type 2 diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, hypercholesterolemia).…”
Get full text

Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study by Reder Rafiq Mohammed Salih, Fadhluddin Nasruddin Shakor, Dalia Ardal Ali, Rafiq Mohammed Salih Rashid

“…In addition, less than 10% of individuals attributed vitamin D shortage to kidney and liver problems, fat malabsorption, obesity, and bariatric surgery. Nevertheless, more than two-thirds (83.3%) of participants defined the positive role of vitamin D in preventing osteoporosis and immune system strengthening (61%). …”
Get full text

Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case–control study by Stefan Teipel, Manas Akmatov, Bernhard Michalowsky, Steffi Riedel-Heller, Jens Bohlken, Jakob Holstiege

“…These included established risk factors, such as depression, hypertension, hearing impairment, nicotine and alcohol abuse, obesity, hypercholesterolaemia, traumatic brain injury, and diabetes. …”
Get full text

Clinical and molecular analyses of isolated central congenital hypothyroidism based on a survey conducted in Japan by Nao Shibata, Chikahiko Numakura, Takashi Hamajima, Kenichi Miyako, Ikuma Fujiwara, Jun Mori, Akihiko Saitoh, Keisuke Nagasaki

“…One and two patients with IGSF1 variant had obesity and intellectual disability, respectively. …”
Get full text

Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro by Xiaoyu Cai, Songxue Wang, Huali Wang, Suwen Liu, Guishan Liu, Huibin Chen, Ji Kang, Hao Wang

“…The molecular mechanism of naringenin in the treatment of obesity were predicted by using network pharmacology. …”
Get full text

The causal relationship of cigarette smoking to metabolic disease risk and the possible mediating role of gut microbiota by Jingda Zhang, Lin Hou, Shanxiang Lei, Yan Li, Guogang Xu

“…Results: The phenomenon that a causal relationship between cigarette smoke (249752 individuals) and gut microbiota (7738 individuals), diabetes (406831 individuals), NAFLD (377998 individuals), hypercholesterolaemia (463010 individuals), and obesity (463010 individuals) was observed using UVMR. …”
Get full text