M6a demethylase FTO regulates the oxidative stress, mitochondrial biogenesis of cardiomyocytes and PGC-1a stability in myocardial ischemia-reperfusion injury by Qiong Jiang, Xuehai Chen, Kezeng Gong, Zhe Xu, Lianglong Chen, Feilong Zhang

“…RT–PCR and Western blot were used to investigate the expression of the fat mass and obesity-associated (FTO) gene. Electrocardiogram, echocardiography, triphenyltetrazolium chloride (TTC) staining and hematoxylin-eosin (HE) staining were used to assess the model and the effect of FTO overexpression. …”
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Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB by Jeanne Durendale Chiadak, Tatjana Arsenijevic, Kevin Verstrepen, Françoise Gregoire, Nargis Bolaky, Valérie Delforge, Véronique Flamand, Jason Perret, Christine Delporte

“…In an obese state, Toll-like receptor-4 (TLR-4) upregulates proinflammatory adipokines secretion including monocyte chemotactic protein-1 (MCP-1) in adipose tissue. …”
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Prevalence of overweight misperception and weight control behaviors among normal weight adolescents in the United States by Kathleen S. Talamayan, Andrew E. Springer, Steven H. Kelder, Emmanuel C. Gorospe, Karen A. Joye

“…These data suggest that obesity prevention programs should address weight misperceptions and the harmful effects of unhealthy weight control methods even among normal weight adolescents.…”
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Cardiometabolic risk factors in the Swedish Werlabs cohort based on self-initiated health screening: cohort profile by Peter Ueda, Kerstin Brismar, Anna Norhammar, Daniel Peter Andersson, Hannah Coudé Adam, Omid Hajimirsadeghi, Lovisa Krantz, Nadia Bandstein Forsberg

“…The most common self-reported chronic disease was hypertension (4.5%), followed by cardiovascular disease (0.9%) and 12.6% reported values of obesity. The prevalence was 2.1% for diabetes, 1.2% for kidney disease (including an estimated glomerular filtration rate of <60 mL/min/1.73 m2), 57.8% for a low-density lipoprotein cholesterol level of >3.0 mmol/L and 4.1% for anaemia (haemoglobin <120 g/L and <130 g/L for women and men, respectively). …”
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The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography by Anne B. Gregory, Kendra K. Lester, Deborah M. Gregory, Laurie K. Twells, William K. Midodzi, Neil J. Pearce

“…Background and Aim. Obesity is associated with an increased risk of cardiovascular disease and may be associated with more severe coronary artery disease (CAD); however, the relationship between body mass index [BMI (kg/m2)] and CAD severity is uncertain and debatable. …”
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Prevalence, Risk Factors, and Fetomaternal Outcomes of Gestational Diabetes Mellitus in Kuwait: A Cross-Sectional Study by Zainab Groof, Ghadeer Garashi, Hamid Husain, Shaikhah Owayed, Shaima AlBader, Hawra’a Mouhsen, Anwar Mohammad, Ali H. Ziyab

“…Due to the lack of knowledge on GDM and the fact that diabetes and obesity are high in Kuwait, this study sought to estimate the prevalence of GDM and determine its risk factors and outcomes. …”
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Caffeic Acid Phenethyl Ester Regulates PPAR’s Levels in Stem Cells-Derived Adipocytes by Luca Vanella, Daniele Tibullo, Justyna Godos, Francesca Romana Pluchinotta, Claudia Di Giacomo, Valeria Sorrenti, Rosaria Acquaviva, Alessandra Russo, Giovanni Li Volti, Ignazio Barbagallo

“…Hypertrophic obesity inhibits activation of peroxisome proliferators-activated receptor gamma (PPARγ), considered the key mediator of the fully differentiated and insulin sensitive adipocyte phenotype. …”
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Prevalence and associated factors of diabetes among adult populations of Hawassa town, southern Ethiopia: A community based cross-sectional study. by Getu Kassa Belete, Hlupheka Lawrence Sithole

“…This presents an opportunity to mitigate diabetes risk through public health measures, including avoiding khat chewing, promoting healthy diets, managing overweight and obesity, implementing community-based screening, enhancing health literacy, and integrating health information into daily life.…”
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Implications of parental lifestyle changes and education level on adolescent offspring weight: a population based cohort study - The HUNT Study, Norway by Erik R Sund, Kirsti Kvaløy, Turid Lingaas Holmen, Marit Naess

“…Objective Obesity tends to cluster in families reflecting both common genetics and shared lifestyle patterns within the family environment. …”
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Orthodontic interventions as a management option for children with residual obstructive sleep apnea: a cohort study protocol by Carlos Flores-Mir, Nathalia Carolina Fernandes Fagundes, Arnaldo Perez-Garcia, Daniel Graf, Giseon Heo

“…Additionally, the association of residual OSA and two comorbidities, obesity and asthma, will be investigated through assessing blood, urine and saliva metabolites. …”
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Plasma Concentrations of Benzylpenicillin and Cloxacillin in Infective Endocarditis—With Special Reference to Delayed Hypersensitivity Reactions by Malin Hägglund, Ulrika Snygg-Martin, Lars Olaison, Michael Stofkoper, Bert Ove Larsson, Magnus Brink

“…TDM might be useful in situations where concentrations are hard to predict, such as severe obesity or kidney failure. Additionally, we found no indication that high plasma concentrations are related to the prevalence of DHR.…”
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Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes by Jiajing Yin, Liping Gu, Yufan Wang, Nengguang Fan, Yuhang Ma, Yongde Peng

“…Obesity-induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. …”
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Diabetic Macular Edema Treatment with Bevacizumab Does Not Depend on the Retinal Nonperfusion Presence by Bogumiła Sędziak-Marcinek, Sławomir Teper, Elżbieta Chełmecka, Adam Wylęgała, Mateusz Marcinek, Mateusz Bas, Edward Wylęgała

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Morphophysiological alterations caused by insertional mutagenesis of contactin 5 (Cntn5) gene in transgenic mice by A. V. Smirnov, N. A. Feofanova, G. V. Kontsevaya, M. V. Anisimova, I. I. Kovrigin, I. A. Serova, M. P. Moshkin, L. A. Gerlinskaya, N. R. Battulin

“…Publications exist that imply that some polymorphisms in the Cntn5 gene are associated with obesity and arterial hypertension in humans. We evaluated core parameters of lipid metabolism and heart activity in mice homozygous and heterozygous for Cntn5 mutation using wild- type animals as control. …”
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Adverse childhood experiences and perceived body size across the life course: a longitudinal study using data from the Canadian Longitudinal Study on Aging (CLSA) by Jean-Eric Tarride, Laura N Anderson, Lauren Griffith, Andrea Gonzalez, Vanessa De Rubeis

“…ACEs are associated with trajectories that are characterised by obesity incidence in both early and later life.…”
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Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo by Marjan Nokhbehsaim, Anna Damanaki, Andressa Vilas Boas Nogueira, Sigrun Eick, Svenja Memmert, Xiaoyan Zhou, Shanika Nanayakkara, Werner Götz, Joni Augusto Cirelli, Andreas Jäger, James Deschner

“…Ghrelin plays a major role in obesity-related diseases which have been shown to be associated with periodontitis. …”
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DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations by Jason Sheng Li, Karen Riggins, Li Yang, Chaorong Chen, Patricia Castro, Wedad Alfarkh, Neda Zarrin-Khameh, Michael E. Scheurer, Chad J. Creighton, Benjamin Musher, Wei Li, Lanlan Shen

“…Top genes differentially methylated between these cohorts included the obesity-protective MFAP2 gene as well as cancer risk susceptibility genes APOL3 and RNASEL. …”
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Cannabinoid Receptor 1 Gene Polymorphisms and Nonalcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and in Healthy Controls by Justyna Kuliczkowska Plaksej, Lukasz Laczmanski, Andrzej Milewicz, A. Lenarcik-Kabza, Anna Trzmiel-Bira, Urszula Zaleska-Dorobisz, Felicja Lwow, Lidia Hirnle

“…Polymorphism of the cannabinoid receptor 1 gene (CNR1) may be responsible for individual susceptibility to obesity and related conditions. Objective. To determine the role of genetic variants of CNR1 in the etiopathology of NAFLD in women with PCOS. …”
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Effect of light fasting diet therapy on lipid metabolism and sex hormone levels in patients with polycystic ovary syndrome combined with infertility by Xiaomei Jiang, Yongfeng Wang, Hong Tang, Jin Ma, Heyue Li

“…Furthermore, TC, TG, and LDL-C levels were significantly reduced in the intervention group compared to the control group (p < .05).Conclusion Light fasting diet therapy, especially with flaxseed powder, improves obesity, lipid, and glucose metabolism disorders in PCOS patients with infertility. …”
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Characterization of Stroke Patients in an Intensive Care Unit by Marianela Planes Fajardo, Georgia Díaz-Perera Fernández, Maylín Isabel Alonso Martínez, Aurora Calzada Fajardo

“…<br /> <strong>Results:</strong> the mean age of the patients was 59.4 years. 20 % were obese, a history of smoking was present in 73.3 % and type 2 diabetes mellitus in 70 %. …”
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