A Case of Exacerbation of Chronic Pancreatitis Against the Background of COVID-19 Complicated by Pancreaticopleural Fistula with Enzymatic Pleurisy by I. I. Kotov, I. Yu. Kalinina, A. R. Propp, D. A. Sulim

“…The causative agent of COVID-19 has a high affinity for angiotensin-converting enzyme 2 receptors, which are present in large numbers on acinar, ductal, and secretory cells of the pancreas. …”
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Conversion of tropical forests to water buffalo pastures in lower Amazonia: Carbon losses and social carbon costs by J. Boone Kauffman, Fernanda M. Souza, Rodolfo F. Costa, Antonio Elves Barreto da Silva, Tiago O. Ferreira, J. Patrick Megonigal, Rasis Ritonga, Adi Gangga, Nisa Novita, Carla F. O. Pacheco, Angelo Fraga Bernardino

“…Based on the estimated numbers of water buffalo for the southern portion of the LPBR and the time since initial disturbance, the annual GHG emissions from this land use are estimated to be 602,846 Mg CO2e year−1 with an SCC as high as US$111,526,524 million year−1. …”
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Circulating MicroRNAs in Patients with Psoriasis Treated with Anti-IL-23: A Cohort Study by Federico Diotallevi, Giulia Matacchione, Anna Campanati, Elena Marinelli Busilacchi, Nadia Viola, Ilaria Pace, Beatrice Fontana, Roberta Roncarati, Massimiliano Bonafè, Manuela Ferracin, Jacopo Sabbatinelli, Fabiola Olivieri

“…T-regulatory cell (Treg) numbers and pro-inflammatory cytokine levels were also assessed. …”
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Progress in voluntary medical male circumcision for HIV prevention supported by the US President’s Emergency Plan for AIDS Relief through 2017: longitudinal and recent cross-sectio... by Carlos Toledo, Melissa Habel, Stephanie M Davis, Jonas Z Hines, Jonathan M Grund, Renee Ridzon, Brittney Baack, Jonathan Davitte, Anne Thomas, Valerian Kiggundu, Naomi Bock, Paran Pordell, Caroline Cooney, Irum Zaidi

“…Objective This article provides an overview and interpretation of the performance of the US President’s Emergency Plan for AIDS Relief’s (PEPFAR’s) male circumcision programme which has supported the majority of voluntary medical male circumcisions (VMMCs) performed for HIV prevention, from its 2007 inception to 2017, and client characteristics in 2017.Design Longitudinal collection of routine programme data and disaggregations.Setting 14 countries in sub-Saharan Africa with low baseline male circumcision coverage, high HIV prevalence and PEPFAR-supported VMMC programmes.Participants Clients of PEPFAR-supported VMMC programmes directed at males aged 10 years and above.Main outcome measures Numbers of circumcisions performed and disaggregations by age band, result of HIV test offer, procedure technique and follow-up visit attendance.Results PEPFAR supported a total of 15 269 720 circumcisions in 14 countries in Southern and Eastern Africa. …”
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Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions by Paul B. L. George, Florent Rossi, Marc Veillette, Amélia Bélanger Cayouette, Samantha Leclerc, Cindy Dumais, Nathalie Turgeon, Caroline Duchaine

“…Factors positively linked to total numbers of ARGs included human and livestock populations; whereas mean annual precipitation was negatively linked to resistance gene quantities. …”
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PCA and PSO based optimized support vector machine for efficient intrusion detection in internet of things by Mutkule Prasad Raghunath, Shyam Deshmukh, Poonam Chaudhari, Sunil L. Bangare, Kishori Kasat, Mohan Awasthy, Batyrkhan Omarov, Rajesh R. Waghulde

“…The quantity of Internet of Things (IoT) devices is increasing rapidly and exponentially. The surge in numbers is accompanied by a significant escalation in security vulnerabilities. …”
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ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

“…The findings will be presented at national and international meetings and conferences and published in peer-reviewed journals.Trial registration numbers NCT02308982, EudraCT201400299735 and ISRCTN15791925; Pre-results.…”
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The emergence of DNAM-1 as the facilitator of NK cell-mediated killing in ovarian cancer by Rachel Pounds, Rachel Pounds, Wayne Croft, Hayden Pearce, Tasnia Hossain, Kavita Singh, Janos Balega, David N. Jeevan, Sudha Sundar, Sudha Sundar, Sean Kehoe, Jason Yap, Jason Yap, Paul Moss, Jianmin Zuo

“…In contrast, NK cell numbers in primary tumour and metastasis were substantially reduced, with downregulation of activatory receptors together with elevated PD-1 expression. scRNA-Seq identified 5 NK cell subpopulations along with increased exhausted and immature NK cells within tumour tissue compared to normal tissue. …”
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A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway by Pengdi Yang, Meiling Fan, Ying Chen, Dan Yang, Lu Zhai, Baoyu Fu, Lili Zhang, Yanping Wang, Rui Ma, Liwei Sun

“…Protein expression levels in the PINK1/Parkin pathway were assessed, and molecular docking and PINK1 mutant analyses were conducted to identify potential targets.Results Ginsenoside Rg1 significantly mitigated ovarian reserve decline, enhancing offspring quantity and quality, increasing the levels of ecdysteroids, preventing ovarian atrophy, and elevating germline stem cell numbers in aged Drosophila. Ginsenoside Rg1 improved superoxide dismutase, catalase activity, and gene expression while reducing reactive oxygen species levels. …”
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A national cross-sectional study on latent profile analysis of occupational fatigue among Chinese nurses in the early post-COVID-19 era by Qiuyang He, Qiuyang He, Jianhua Ren, Jianhua Ren, Guoyu Wang, Guoyu Wang, Yonghong Wang, Yonghong Wang

“…The escalation in patient numbers and the high incidence of infections among healthcare workers have intensified occupational fatigue. …”
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Randomized controlled trial of cognitive behavioral therapy versus health education for sleep disturbance and fatigue following stroke and traumatic brain injury by Lucy Ymer, Adam McKay, Dana Wong, Kate Frencham, Natalie Grima, Monique Roper, Sylvia Nguyen, Jade Murray, Gershon Spitz, Jennie Ponsford

“…ANZCTR Trial registration numbers: 1261700087830; 12617000879369 …”
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A Resource-Efficient Multi-Entropy Fusion Method and Its Application for EEG-Based Emotion Recognition by Jiawen Li, Guanyuan Feng, Chen Ling, Ximing Ren, Xin Liu, Shuang Zhang, Leijun Wang, Yanmei Chen, Xianxian Zeng, Rongjun Chen

“…Experiments were conducted using the DEAP dataset, aiming to find a suitable scheme regarding similarity measures, time windows, and input numbers of channel data. The results reveal that DTW yields the best performance in similarity measures with a 5 s window. …”
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Efficacy of Fat Supplements with Different Unsaturated/Saturated FA Ratios Undergoing First Postpartum Ovulation in Lactating Anovulatory Goats by Caroline P. Silva, César C. L. Fernandes, Juliana P. M. Alves, Camila M. Cavalcanti, Felipe B. B. Oliveira, Alfredo J. H. Conde, Diana Celia S. N. Pinheiro, Darcio I. A. Teixeira, Anibal C. Rego, Davide Rondina

“…The algal and linseed groups showed lower feed intake (<i>p</i> < 0.001) and higher (<i>p</i> < 0.001) triglyceride levels/follicle numbers, respectively. After estrus induction, no differences were observed in estrus response; however, the linseed group showed more and larger growing follicles (<i>p</i> = 0.016 and <i>p</i> < 0.01), a higher ovulation rate (<i>p</i> < 0.05), a larger CL area (<i>p</i> < 0.05), and higher progesterone levels (<i>p</i> < 0.001). …”
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Nomograms Predicting Survival, Recurrence and Beneficiary Identification of Adjuvant Chemotherapy in Treatment-naïve Patients with Rectal Cancer who Underwent Upfront Curative Rese... by Yukihide Kanemitsu, MD, Tomofumi Uotani, MD, Shunsuke Tsukamoto, PhD, Hideki Ueno, PhD, Megumi Ishiguro, PhD, Soichiro Ishihara, PhD, Koji Komori, PhD, Kenichi Sugihara, PhD, Study Group for Nomogram of the Japanese Society for Cancer of the Colon and Rectum

“…In the training cohort, age predicted survival, venous invasion predicted recurrence, and sex, tumor location, histological type, preoperative carcinoembryonic antigen, invasion depth, lymphatic invasion, positive radial margin, and numbers of metastatic nodes and examined nodes predicted both. …”
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Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019 by Saeid Safiri, Jessica A. Grieger, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Asra Fazlollahi, Mark J. M. Sullman, Nahid Karamzad, Fikrettin Sahin, Kuljit Singh, Gary S. Collins, Ali-Asghar Kolahi

“…The burden was reported in terms of numbers, proportions, and age-standardised rates per 100,000, accompanied by corresponding 95% uncertainty intervals (UIs). …”
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Information Security and Artificial Intelligence&#x2013;Assisted Diagnosis in an Internet of Medical Thing System (IoMTS) by Pi-Yun Chen, Yu-Cheng Cheng, Zi-Heng Zhong, Feng-Zhou Zhang, Neng-Sheng Pai, Chien-Ming Li, Chia-Hung Lin

“…For a symmetric cryptography scheme, this study proposed a key generator combining a chaotic map and Bell inequality and generating unordered numbers and unrepeated 256 secret keys in the key space. …”
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The pet trade of native species outside of their natural distributions within Australia is a biosecurity risk by Adam Toomes, Oliver C. Stringham, Stephanie Moncayo, Katherine G. W. Hill, Jacob Maher, Freyja Watters, Sebastian Chekunov, Pablo García‐Díaz, Lewis Mitchell, Joshua V. Ross, Phillip Cassey

“…Our results indicate that the “domestic non‐native” trade is widespread in Australia and that, if captive pets escape or are released into the wild in sufficient numbers, there is a risk of establishment for most of these species. …”
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Antibiotic-mediated dysbiosis leads to activation of inflammatory pathways by Jemma J. Taitz, Jemma J. Taitz, Jian Tan, Jian Tan, Duan Ni, Duan Ni, Camille Potier-Villette, Camille Potier-Villette, Georges Grau, Georges Grau, Ralph Nanan, Ralph Nanan, Ralph Nanan, Laurence Macia, Laurence Macia, Laurence Macia

“…The MLNs and spleen showed changes only to DC numbers. Splenocytes from antibiotic-treated mice stimulated ex vivo exhibited increased production of TNF. …”
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Enriched environment rescues bisphenol A induced anxiety-like behavior and cognitive impairment by modulating synaptic plasticity by Jiong Li, Guangyin Yu, Laijian Wang, Wenjun Zhang, Wenya Ke, Yifei Li, Danlei Liu, Keman Xie, Yuanyuan Xu, Caihui Cha, Guoqing Guo, Jifeng Zhang

“…Furthermore, exposure to BPA led to a decrease in both the density and maturity of dendritic spines, as well as a reduction in neurite length and branch numbers. PSD-95, GluA1, and NR2A expression were down-regulated, and excitatory synaptic transmission was decreased. …”
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Implementing a workplace participatory approach to support working caregivers in balancing their work, private life and informal care: results of a process evaluation by Eline E. Vos, Simone R. de Bruin, Allard J. van der Beek, Denise J.M. Smit, Karin I. Proper

“…Abstract Background Many organizations are faced with growing numbers of employees who combine their jobs with informal caregiving responsibilities. …”
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