Enhanced Drug Skin Permeation by Azone-Mimicking Ionic Liquids: Effects of Fatty Acids Forming Ionic Liquids by Takeshi Oshizaka, Shunsuke Kodera, Rika Kawakubo, Issei Takeuchi, Kenji Mori, Kenji Sugibayashi

“…In the present study, fatty acids with different carbon numbers (caprylic acid: C8, capric acid: C10, lauric acid: C12, myristic acid: C14, and oleic acid: C18:1) were selected and used with ε-caprolactam to prepare various IL-Azones in the search for a more effective IL-Azone. …”
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Whole-genome association studies of distribution of developmental abnormalities and other breeding-valuable qualitative traits in offspring of the Russian large-white boars by A. A. Traspov, O. V. Kostyunina, A. A. Belous, T. V. Karpushkina, N. A. Svejenceva, N. A. Zinovieva

“…This study confirms the relevance of using the single SNP detection according to the single trait approach in associative studies, even for small sample numbers.…”
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Mortality of elder financial and psychological abuse victims in rural Malaysia: a prospective cohort study by Raudah Mohd Yunus, Farizah Hairi, Noran N Hairi, Wan Yuen Choo, Sajaratulnisah Othman, Rajini Sooryanarayana, Norliana Ismail, Sharifah Nor Ahmad, Inayah Abdul Razak, Devi Peramalah, Awang Bulgiba Awang Mahmud, Halima B Awang, Siti Zaharah Jamaludin, Jamali Samsuddin, Mohammad Mafrukhin Mokhtar, Syed Mohd Fauzi, Zainudin Mohd Ali

“…Individuals with severe cognitive impairment were excluded.Outcome measure Mortality data were provided by the Malaysian National Registration Department and linked to respondents’ national identification numbers. Kaplan-Meier curves and Cox regression were used to examine victims’ survival periods and the impact of abuse on risk of death.Results Overall, 450 respondents (23.4%) died after 7 years. …”
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Impact of Bone Marrow Aspirate Tregs on the Response Rate of Younger Newly Diagnosed Acute Myeloid Leukemia Patients by Mario Delia, Paola Carluccio, Anna Mestice, Claudia Brunetti, Francesco Albano, Giorgina Specchia

“…The possible prognostic value of such an immunological player as BMA Tregs in the diagnostic and successive phases of AML needs to be confirmed in larger patient numbers.…”
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Resistance to P. brasiliensis Experimental Infection of Inbred Mice Is Associated with an Efficient Neutrophil Mobilization and Activation by Mediators of Inflammation by Felipe Fornias Sperandio, Gisele Pesquero Fernandes, Ana Carolina Silvério Cerqueira Mendes, Giulia Maria de Alencar Castro Bani, Vera Lucia Garcia Calich, Eva Burger

“…Susceptible mice produced higher numbers of PMN; however, these cells were less effective in killing the fungi. …”
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Thermocapillary convection in superimposed fluids confined within superhydrophobic surfaces of a microchannel by Radi A. Alsulami, Kanchathan Wasuwatthanakul, Kannan Premnath, Mutabe Aljaghtham, Saad Adam

“…This is achieved by deriving a new analytical solution for thermocapillary convection between two solid walls, uniquely subject to the Navier slip condition and where the bottom surface is heated nonuniformly via a sinusoidal variation, under the limit of zero Reynolds and Marangoni numbers. The derived expressions for the flow field arising from the prevailing surface tension gradient are then explicitly parameterized by a dimensionless slip coefficient obtained by combining the Navier slip length and the wavenumber of the imposed temperature variation on the bottom surface, along with the ratios of the properties of fluids and their thicknesses. …”
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The current and future cancer burden in the Gulf Cooperation Council (GCC) countries by Saleh A. Alessy, Saleh A. Alqahtani, Jerome Vignat, Amid Abuhmaidan, Amani E. L. Basmi, Najla Al Lawati, Ameera Ali A‐Nooh, Wael Shelpai, Samar Alhomoud, Ali Al‐Zahrani, Freddie Bray, Ariana Znaor

“…Methods The estimated numbers of new cancer cases and deaths were extracted from the GLOBOCAN database developed by the International Agency for Research on Cancer; new cancer cases, cancer deaths, and corresponding age‐standardized incidence and mortality rates for the year 2020 are presented. …”
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Cardiac Migration of Endogenous Mesenchymal Stromal Cells in Patients with Inflammatory Cardiomyopathy by Caroline Schmidt-Lucke, Felicitas Escher, Sophie Van Linthout, Uwe Kühl, Kapka Miteva, Jochen Ringe, Thomas Zobel, Heinz-Peter Schultheiss, Carsten Tschöpe

“…A strong correlation was found between the TCG of circulating MSC and numbers of MSC (CD45−CD34−CD90+CD105+) in EMB (r=-0.73, P<0.005). …”
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Foliar application of humic liquid extract from vermicompost improves garlic (Allium sativum L.) production and fruit quality by D. M. Balmori, C. Y. A. Domínguez, C. R. Carreras, S. M. Rebatos, L. B. P. Farías, F. G. Izquierdo, R. L. L. Berbara, Andrés Calderín García

“…The HEVC foliar application in 1:40 v:v ratio was the most promising treatment in terms of increases in fruit quality indices, promoting improvements in bulb caliber, numbers of garlic cloves and internal fruit content. …”
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Simulation of β-induced Alfvén eigenmode instabilities and mode transition for HL-3 hybrid scenario by Yunpeng Zou, Vincent S Chan, Yasushi Todo, Ruirui Ma, Miao Xue, Xiaoran Zhang, Yiren Zhu, Wei Chen

“…A nonlinear simulation with multiple toroidal mode numbers indicates that the n = 2 β -induced AE (BAE) is excited initially in the linear stage and the n = 1 FB mode has the highest nonlinear saturation level. …”
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GastroFuse-Net: an ensemble deep learning framework designed for gastrointestinal abnormality detection in endoscopic images by Sonam Aggarwal, Isha Gupta, Ashok Kumar, Sandeep Kautish, Abdulaziz S. Almazyad, Ali Wagdy Mohamed, Frank Werner, Mohammad Shokouhifar

“…GastroFuse-Net was developed by combining features extracted from two different CNN models with different numbers of layers, integrating shallow and deep representations to capture diverse aspects of the abnormalities. …”
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Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses by Kai Wang, Ling Qin, Huan Lin, Mengke Yao, Junhan Cao, Qing Zhang, Changfeng Qu, Yingying He, Jinlai Miao, Ming Liu

“…M-Gly treatment improved skin appearance and reduced mast cell numbers, while also elevating antioxidant levels, including superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). …”
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Spatial Analysis of Building Density and Liquefaction Spread in Izmit Bay and its Surroundings by Arzu Erener, Metin Aşcı, Gül Gülsoy, Aydın Üstün, Muhammed Ali Güvenaltın, Erman Şentürk, Sefa Yalvaç, Fatma Canaslan Çomut, T. Serkan Irmak, Haluk Konak, Pakize Küreç Nehbit, Efdal Kaya, Burak Kotan, Selin Öye

“…Since December 2017, with the support of Kocaeli Metropolitan Municipality and with the leadership of Kocaeli University Geomatic Department, TÜBİTAK project numbered 117Y155 and titled “Monitoring of Vertical Displacements in East Marmara (Izmit Bay) with Multi-Band InSAR and GNSS Techniques, Investigation of the Relationship Between Ground Collapse and Building Density and Liquefaction" studies have been initiated to determine the risks in the Izmit Bay area. …”
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Evaluating Sampling Designs to Survey Fish Diversity in Lakes From Northern Temperate Zones by Erik García‐Machado, Eric Normandeau, Guillaume Côté, Isabeau Caza‐Allard, Charles Babin, Louis Bernatchez

“…However, we found that, under certain circumstances, stratified sampling outperformed random sampling, requiring lower numbers of samples to detect the same species diversity. …”
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“I definitely cannot afford to be feeling poorly if there’s no need to be”: a qualitative evaluation of antiviral uptake following suspected occupational exposure to avian influenz... by Riinu Pae, Lucy Findlater, Richard Amlôt, Fernando Capelastegui, Gavin Dabrera, Clare Humphreys, Jharna Kumbang, Isabel Oliver

“…Abstract Background Growing numbers of people have been potentially exposed to avian influenza (AI), as the United Kingdom has managed the largest and most sustained series outbreaks in recent years. …”
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The effect of physical cues on platelet storage lesion by Lihan Cheng, Lu Wang, Shichun Wang, Qi Liu, Ronghua Diao, Chunyan Yao

“…Agitation maintains more cell numbers, better cell morphology, and lower metabolism rate in platelets, and keeps the low activation state of platelets throughout the storage period. …”
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Advancing the understanding of Naegleria fowleri: Global epidemiology, phylogenetic analysis, and strategies to combat a deadly pathogen by Awadh Alanazi, Sonia Younas, Hasan Ejaz, Muharib Alruwaili, Yasir Alruwaili, Bi Bi Zainab Mazhari, Muhammad Atif, Kashaf Junaid

“…We identified 488 PAM cases globally, reported since 1962, with the highest numbers in the US, Pakistan, and Australia. A phylogenetic analysis of 41 N. fowleri ITS-1, 5.8S, ITS-2 region-based sequences showed genotypic diversity, with genotypes II and III being the most prevalent in Asia, North America, and Europe. …”
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Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer by Bin Han, Fang-yuan Mao, Yong-liang Zhao, Yi-pin Lv, Yong-sheng Teng, Mubing Duan, Weisan Chen, Ping Cheng, Ting-ting Wang, Zhong-yuan Liang, Jin-yu Zhang, Yu-gang Liu, Gang Guo, Quan-ming Zou, Yuan Zhuang, Liu-sheng Peng

“…The tumor microenvironment can suppress NK cell activity, and there is a great clinical interest in understanding whether modulating tumor-mediated NK cell suppression and/or boosting preexisting NK cell numbers in cancer patients is therapeutically viable. …”
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Efficient biosynthesis of β-caryophyllene by engineered Yarrowia lipolytica by Young-Kyoung Park, Lucie Studena, Piotr Hapeta, Ramdane Haddouche, David J. Bell, Pablo Torres-Montero, Jose Luis Martinez, Jean-Marc Nicaud, Adriana Botes, Rodrigo Ledesma-Amaro

“…Results Two genes, tHMG1 from S. cerevisiae to boost the mevalonate pool and QHS1 from Artemisia annua, were expressed under different promoters and copy numbers in Y. lipolytica. The co-expression of 8UAS pEYK1-QHS1 and pTEF-tHMG1 in the obese strain yielded 165.4 mg/L and 201.5 mg/L of β-caryophyllene in single and double copies, respectively. …”
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Isatidis root polysaccharides ameliorates post-weaning diarrhea by promoting intestinal health and modulating the gut microbiota in piglets by Miao Zhou, Zenghao Yan, Deqin Wang, Chuyuan Li, Leli Wang, Rui Li, Jie Yin, Yulong Yin

“…Key intestinal health parameters, including villus height, villus height-to-crypt depth ratio, and goblet cell numbers, showed linear and quadratic increases in both the jejunum and ileum (p < 0.05), while crypt depth decreased significantly (p < 0.01). …”
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