Genomic analysis and replication kinetics of the closely related EHV-1 neuropathogenic 21P40 and abortigenic 97P70 strains by Eslam Mohamed, Ines Zarak, Nick Vereecke, Sebastiaan Theuns, Kathlyn Laval, Hans Nauwynck

“…Both strains exhibited a nucleotide identity of 99.96%, with only seven genetic mutations in ORFs 13, 24, 30, 32, 40, 65, and 71. …”
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A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism by Shiben Zhu, Ziyu Hao, Qihang Chen, Xiaoliu Liu, Wenyan Wu, Fang Zhang

“…Utilizing 139 genome-wide significant single nucleotide polymorphisms (SNPs) as instrumental variables (IVs) for TL, forward MR analyses indicated a negative causal effect of TL on hyperthyroidism. …”
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Description of a new Ornithodoros (Pavlovskyella) (Ixodida: Argasidae) tick species from Pakistan by Abid Ali, Mehran Khan, Muhammad Numan, Abdulaziz Alouffi, Mashal M. Almutairi, Ronel Pienaar, Minique H. de Castro, Lidia Chitimia-Dobler, Sebastián Muñoz-Leal, Ben J. Mans, Ala Tabor

“…Phylogenetic analyses of the full-length mitochondrial genome and the 18S and 28S ribosomal RNA genes, combined with pairwise nucleotide comparisons of cox1, cox2, atp8, atp6, cox3, nad3, nad5, nad4, nad4L, nad6, cytb, nad1, nad2, 12S rDNA, 16S rDNA, 18S rDNA and 28S rDNA further support that the new species belongs to the Pavlovskyella subgenus, clustering with O. tholozani, Ornithodoros verrucosus and Ornithodoros tartakovskyi.…”
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An initial exploration of core collection construction and DNA fingerprinting in Elymus sibiricus L. using SNP markers by Xinrui Li, Xinrui Li, Xinrui Li, Daping Song, Mingfeng Li, Daxu Li, Minghong You, Yan Peng, Jiajun Yan, Shiqie Bai

“…To more comprehensively aggregate E. sibiricus germplasm resources at a lower cost and to more accurately utilize its genetic variation, this study conducted a preliminary exploration of core germplasm collections and fingerprinting of E. sibiricus using single nucleotide polymorphism (SNP) markers. By combining multiple evaluation measures with weighted processing, we successfully identified 36 materials from 90 wild E. sibiricus samples to serve as a core collection. …”
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The role of VNTR aggrecan gene polymorphism in the development of osteoarthritis in women by D. A. Shapovalova, A. V. Tyurin, S. S. Litvinov, E. K. Khusnutdinova, R. I. Khusainova

“…A study of the aggrecan gene (ACAN) VNTR polymorphism, which is represented by a variable number of 57 nucleotide repeats, was performed. We searched for associations between the VNTR locus and OA in general and with an account of the localization of the pathological process, as well as with the presence of uCTD signs. …”
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GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway by Yaowen Zhang, Yixin Yang, Shanshan Kuang, Yang Zhang, Hancheng Qin, Jisheng Xie

“…Amino acid metabolism, including ATP production, nucleotide synthesis, and redox homeostatic processes, are associated with proliferation and differentiation of tumor cells. …”
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MORPHOLOGY, MOLECULAR IDENTIFICATION, PATHOGENICITY AND FIRST REPORT OF FUSARIUM EQUISETI ASSOCIATED WITH ROOT ROT AND WILT DISEASE OF CATHARANTHUS ROSEUS IN BAGHDAD, IRAQ by Lara B. Yasir, Bushra Subair Abdulsada Almaliky

“…The results of the molecular identification showed that the three isolates FeL1, FeL2 and FeL9 belong to the F. equiseti and they showed a conformity ratio of 99.60, 99.39 and 95.97 respectively when compared with the nucleotide sequences of isolates of F. equiseti gene bank of Brazil JQ936262, Ghana OL998428 and China GU586830 respectively. …”
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Nuclear and chloroplast genome variability in leek (Allium porrum L.) by E. A. Dyachenko, T. M. Seredin, M. A. Filyushin

“…Therefore, in this work, we studied the nuclear variability (AFLP) and the chloroplast (nucleotide sequence analysis) genomes using a broad sample. …”
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Pathway Analysis of Metabolic Syndrome Using a Genome-Wide Association Study of Korea Associated Resource (KARE) Cohorts by Unjin Shim, Han-Na Kim, Yeon-Ah Sung, Hyung-Lae Kim

“…However, GWASs focus more on individual single-nucleotide polymorphisms (SNPs), explaining only a small portion of genetic heritability. …”
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Genetic Variants of SIRT1 Gene Promoter in Type 2 Diabetes by Shuchao Pang, Zhengjun Zhang, Yu Zhou, Jie Zhang, Bo Yan

“…A total of 20 genetic variants, including 7 single-nucleotide polymorphisms (SNPs), were identified. Five heterozygous genetic variants (g.4114-15InsA, g.4801G > A, g.4816G > C, g.4934G > T, and g.4963_64Ins17bp) and one SNP (g.4198A > C (rs35706870)) were identified in T2D patients, but in none of the controls. …”
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Molecular Epidemiology of Human Norovirus Variants from Outbreaks in Zhejiang Province, China, during 2021 by Yi Sun, Yongjuan Yuan, Haiyan Mao, Lingxuan Su, Qiong Ge, Jian Gao, Changping Xu, Liming Gong

“…Furthermore, the whole genomes of positive samples were sequenced, enabling the characterization of both nucleotide and amino acid differences within the virus. …”
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Comparative Analysis of Seventeen Mitochondrial Genomes of Mileewinae Leafhoppers, Including the Unique Species Mileewa digitata (Hemiptera: Cicadellidae: Mileewinae) From Xizang,... by Hongli He, Bin Yan, Xiaofei Yu, Maofa Yang

“…Gene arrangement among the 17 genomes mirrors that of other Mileewinae species. Analyses of nucleotide diversity and evolutionary rates indicate purifying selection on PCGs, with atp8 exhibiting the greatest variability and evolutionary rate, whereas cox1 shows the least. …”
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Exploration of different quantitative polymerase chain reaction-based genotyping methods to distinguish Apcmin/+ mice from wildtype mice. by Yuting Sun, Tingyu Zhou, Silin Ye, Effie Yin Tung Lau, Yao Zeng, Jessie Qiaoyi Liang

“…Various molecular methods have been established for genotyping single-nucleotide variants (SNVs). However, despite the widespread availability of quantitative polymerase chain reaction (qPCR) instruments in biomedical laboratories, the lack of professional analytical tools impedes the application of qPCR in genotyping. …”
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Analysis of the Genomes and Adaptive Traits of <i>Skermanella cutis</i> sp. nov., a Human Skin Isolate, and the Type Strains <i>Skermanella rosea</i> and <i>Skermanella mucosa</i> by Yujin Choi, Munkhtsatsral Ganzorig, Kyoung Lee

“…Genome sequencing and phylogenomic analyses revealed that the strain TT6^T is most closely related to <i>S. rosea</i> M1^T, with average nucleotide identity and digital DNA–DNA hybridization values of 94.14% (±0.5%) and 64.7%, respectively. …”
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Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease by Nolubabalo Unati Nqebelele, Caroline Dickens, Therese Dix-Peek, Raquel Duarte, Saraladevi Naicker

“…Genome wide association studies identified significant single nucleotide polymorphism (SNP) associations with CKD at the uromodulin (UMOD) locus. …”
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Мutants of inflorescence development in alfalfa (Medicago sativa L.) by N. I. Dzyubenko, E. A. Dzyubenko

“…M. truncatula and alfalfa share highly conserved nucleotide sequences and exhibit nearly perfect  synteny between the two genomes. …”
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Study of Association of Vitamin D Receptor Gene Polymorphisms with Diabetic Nephropathy by Bhuiya Esha, Saravanan Yogaprabhu, Janaki Sneha, Karthick Vijayalakshmi, Viswanathan Mohan, Venkatesan Radha, Dhanasekaran Bodhini

“…The functions of vitamin D are mediated through vitamin D receptor (VDR). Three single nucleotide polymorphisms (SNPs) in VDR gene, namely, TaqI (rs731236), ApaI (rs7975232), and BsmI (rs1544410), have been widely studied in association with diabetes and nephropathy. …”
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In silico analysis of SNPs and miRNAs of KCTD13, CSDE1, SLC6A1 genes associated with autism spectrum disorder by Kübra Çoruh Kınalı, Ebru Özkan Oktay, Mesut Karahan

“…Abstract Background Single nucleotide polymorphism (SNP) is called changes in a single base sequence in DNA between individuals. …”
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MAO-B Polymorphism Associated with Progression in a Chinese Parkinson’s Disease Cohort but Not in the PPMI Cohort by Shi-Shuang Cui, Ling-Yu Wu, Gen Li, Juan-Juan Du, Pei Huang, Jin Liu, Yun Ling, Kang Ren, Zhong-Lue Chen, Sheng-Di Chen

“…A panel containing 30 PD risk single nucleotide polymorphisms was tested. Progression rates of each scale were derived from random-effect slope values of mixed-effects regression models. …”
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Causal effects between gut microbiota and endometriosis: a two-sample Mendelian randomisation study by Tiefeng Cao, Yunfei Wang, Shen Huimin

“…Cochran’s Q statistics was used to test the heterogeneity of instrumental variables (IVs); MR-Egger regression was used to test horizontal pleiotropy; MR-PRESSO and leave-one-out sensitivity analysis were applied to find significant outliers.Result A total of 1131 single nucleotide polymorphisms (SNPs) were collected as IVs for 196 GM taxa with endometriosis as the outcome. …”
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