Functional Genetic Variant in ATG5 Gene Promoter in Acute Myocardial Infarction by Yexin Zhang, Xiaohui He, Jiarui Li, Wentao Yang, Yinghua Cui, Shuchao Pang, Haihua Wang, Bo Yan

“…The results showed that a total of 15 genetic variants including 6 single-nucleotide polymorphisms (SNPs) in the ATG5 gene promoter were found in this study population. …”
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Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location by Christopher Wills, Katie Watts, Amy Houseman, Timothy S. Maughan, David Fisher, Nada A. Al-Tassan, Richard S. Houlston, Valentina Escott-Price, Jeremy P. Cheadle

“…We studied 1899 patients with advanced CRC (514 had proximal colonic, 493 distal colonic and 892 rectal tumours) and carried out genome-wide association studies for survival. Single nucleotide polymorphisms (SNPs) suggestive of association (P < 1.0 × 10–5) were tested for replication in 5078 CRC patients from the UK Biobank. …”
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Identification of genome compositions in allopolyploid species of the genus Elymus(Poaceae: Triticeae) in the Asian part of Russia by CAPS analysis by A. V. Agafonov, E. V. Shabanova (Kobozeva), S. V. Asbaganov, A. V. Mglinets, V. S. Bogdanova

“…Boreal  StH-genomic species endemic for Russia are the least studied. On the basis of nucleotide sequences from public  databases, TaqI restrictase was selected, as it produced patterns of restriction fragments specific for St, H, and Y  haplomes easily recognizable in agarose gel. …”
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Optimization of Silkworm Pupae Fermentation by Response Surface Methodology and Products Taste Characteristics Study by Fangli QIN, Siyuan WANG, Yuxiao ZOU, Erna LI, Lixia MU, Qingrong LI

“…Compared with those in unfermented silkworm pupae, the free amino acid, nucleotide, and organic acid contents in fermented silkworm pupae were significantly increased (P<0.05), reaching 52.19±0.11, 1.01±0.03, and 65.54±1.61 mg/g, respectively. …”
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Polymorphism in the TRP8 gene in Kyrgyz population: putative association with highland adaptation by V. N. Babenko, Ж. Т. Isakova, E. T. Talaibekova, D. A. Asambaeva, V. F. Kobzev, T. A. Potapova, M. I. Voevoda, A. A. Aldashev

“…The structural variability of the TRPM8 gene for five single-nucleotide polymorphisms (SNPs) has been studied in Kyrgyz population. …”
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Preimplantation genetic testing for four families with severe combined immunodeficiency: Three unaffected livebirths by Lingyun Zhang, Lei Feng, Hao Shi, Wenbin Niu, Yanchi Wang, Bei Bu, Yidong Liu, Xiao Bao, Wenyan Song, Haixia Jin, Yingpu Sun

“…The strategy of PGT-M started with a biopsy of the trophectoderm cells of embryos, and the whole genome was amplified by multiple replacement amplification (MDA). Then, the single nucleotide polymorphisms (SNPs) in the region upstream and downstream of the mutation site were subsequently identified via karyomapping, and the results were analyzed via SNPs linkage analysis. …”
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OsLAP3/OsSTRL2, encoding a rice strictosidine synthase, is required for anther cuticle formation and pollen exine patterning in rice by Dai-bo Chen, Ran Zhou, Ran Zhou, Hui-min Wang, Pei-pei Zhang, Zheng-fu Yang, Zheng-fu Yang, Dan-dan Xuan, Ying-xin Zhang, Xiao-deng Zhan, Li-yong Cao, Li-yong Cao, Shi-hua Cheng, Lian-ping Sun, Lian-ping Sun

“…Functional analysis, including complementation and CRISPR/Cas9-based gene editing, confirmed that the 2-nucleotide deletion in the OsLAP3 is responsible for the male sterility phenotype. …”
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Analysis of the relationship between environmental particulate matter exposure and congenital diseases, as well as the epidemiological trends and burden of impact on newborns by Mulati Julaiti, Dilixiati Wubuli, Tingting Cui, Nadire Nijiati, Pengfei Huang, Bowen Hu

“…Methods: The study employed Mendelian randomization, utilizing single nucleotide polymorphisms as instrumental variables, to estimate the causal effect of environmental Particulate on congenital diseases. …”
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Application of alternative <i>de novo</i> motif recognition models for analysis of structural heterogeneity of transcription factor binding sites: a case study of FOXA2 binding sit... by A. V. Tsukanov, V. G. Levitsky, T. I. Merkulova

“…However, this model does not take into account dependencies between nucleotide occurrences in different site positions. …”
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Assessment of Self-Activation and Inhibition of Wheat Coiled-Coil Domain Containing NLR Immune Receptor Yr10_CG by Nan Wu, Wanqing Jiang, Zhaoxia Xiang, Raheel Asghar, Mahinur S. Akkaya

“…Plant immunity is largely governed by nucleotide-binding leucine-rich repeat receptor (NLR). …”
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Endangered Pinto/Northern Abalone (Haliotis kamtschatkana) are Panmictic Across Their 3700 km Range Along the Pacific Coast of North America by J. L. Dimond, J. V. Bouma, F. Lafarga‐De la Cruz, K. J. Supernault, T. White, D. A. Witting

“…We employed reduced representation sequencing (RADseq) to generate single nucleotide polymorphism (SNP) data, assessing population connectivity and potential adaptive variation at 12 locations across the full range from Alaska to Mexico. …”
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Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in ca... by Ghazi Elamin, Ghazi Elamin, Zhichao Zhang, Depika Dwarka, Kabange Kasumbwe, John Mellem, Nompumelelo P. Mkhwanazi, Paradise Madlala, Paradise Madlala, Mahmoud E. S. Soliman

“…Genetic variations and dysregulation of Bcl-2 are particularly significant in cancer, as they disrupt the normal apoptotic machinery, enabling cancer cells to evade programmed cell death. Single nucleotide polymorphisms (SNPs) are considered viable diagnostic and therapeutic biomarkers for various cancers. …”
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First whole genome report of Mangrovibacter phragmitis PSU-3885–11 isolated from a patient in Thailand by Nattarika Chaichana, Thunchanok Yaikhan, Mingkwan Yingkajorn, Nonthawat Thepsimanon, Sirikan Suwannasin, Kamonnut Singkhamanan, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Komwit Surachat

“…Moreover, comparative genomic analysis showed 99.32 % average nucleotide identity (ANI) similar to M. phragmitis MP23, and several antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) were identified in the PSU-3885–11 genome which may contribute to its ability to survive in diverse environments, including human hosts. …”
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Association of Race and Major Adverse Cardiac Events (MACE): The Atherosclerosis Risk in Communities (ARIC) Cohort by Ericha G Franey, Donna Kritz-Silverstein, Erin L Richard, John E Alcaraz, Caroline M Nievergelt, Richard A Shaffer, Vibha Bhatnagar

“…To evaluate the association of self-reported race with major adverse cardiac events (MACE) and modification of this association by paraoxonase gene (PON1, PON2, and PON3) single nucleotide polymorphisms (SNPs). Methods. Included in this longitudinal study were 12,770 black or white participants from the Atherosclerosis Risk in Communities (ARIC) cohort who completed a baseline visit (1987–1989) with PON genotyping. …”
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Search for signals of positive selection of circadian rhythm genes <i>PER1</i>, <i>PER2</i>, <i>PER3</i> in different human populations by A. I. Mishina, S. Y. Bakoev, A. Y. Oorzhak, A. A. Keskinov, Sh. Sh. Kabieva, A. V. Korobeinikova, V. S. Yudin, M. M. Bobrova, D. A. Shestakov, V. V. Makarov, L. V. Getmantseva

“…In this article, we searched for signals of single nucleotide polymorphisms (SNPs) under selection pressure in people of different populations. …”
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Identification of the sex determination region and the development of a marker to distinguish males and females in megai abalone (Haliotis gigantea) by Taito Kina, Motoyuki Hara, Shotaro Hirase, Kiyoshi Kikuchi

“…By calculating the fixation index value between 10 females and 10 males, we identified a genomic region spanning approximately 2 Mb that exhibited nucleotide sequence divergence between the sexes on chromosome 18. …”
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Genetic Variations of Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients by Ji Hyun Yi, Yang-Je Cho, Won-Joo Kim, Min Goo Lee, Ji Hyun Lee

“…We examined the association of ABCC2 single-nucleotide polymorphisms and haplotype frequencies with VPA related to adverse reactions. …”
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Genetic Diversity of <i>Diaphorina citri</i> and Its Endosymbiont Across Diffusion Frontier and Epidemic Areas of Citrus Huanglongbing in China by Jin Yang, Ai-Jun Huang, Jun Zhou, Ping You, Xiang Li, Han Luo, Long Yi

“…</i> C. ruddii in different regions showed low haplotype diversity and nucleotide diversity. While the genetic variation in <i>D. citri</i> populations primarily occurred within populations, the endosymbiont showed contrasting patterns in the HLB epidemic areas. …”
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Gene–Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy by Farzana Jasmine, Armando Almazan, Yuliia Khamkevych, Maria Argos, Mohammad Shahriar, Tariqul Islam, Christopher R. Shea, Habibul Ahsan, Muhammad G. Kibriya

“…From a six-year follow-up study on 7000 adults exposed to As, we reported the associations of single-nucleotide variation in tumor tissue and gene expression. …”
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Salvage pathway of vitamin B12 absorption in chickens with mutant tumor virus a receptor by Yun Ji Shin, Jin-Kyoo Kim, Seung Je Woo, Byung Chul Park, Jae Yong Han

“…We found four TVA variants comprising the wild type (TVAWT), a single nucleotide polymorphism variant (TVASNP), and two partial deletions in the splicing branch point region (TVAR). …”
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