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861
Weak genetic divergence and signals of adaptation obscured by high gene flow in an economically important aquaculture species
Published 2025-02-01“…The captive population, which was reared for over 25 years was the most genetically distinct population and exhibited reduced nucleotide diversity, attributable to inbreeding. Individuals from populations that were separated both geographically and temporally did not show detectable genetic differences, illustrating the consequences of human intervention in the form translocation of animals between farms, hatcheries and natural settings. …”
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862
Association of P2X7 polymorphisms on Type 2 diabetes mellitus susceptibility and diabetic complications.
Published 2025-01-01“…<h4>Objectives</h4>This case-control study aims to clarify the impact of single nucleotide polymorphisms (SNPs) within the P2X7 gene on susceptibility to type 2 diabetes mellitus (T2DM) and to evaluate their association with diabetic complications.…”
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863
Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase
Published 2022-03-01“…It was shown that the proportion (%) of abortive elongation products of a PGO primer depends on buffer ionic strength, nucleotide sequence of the primer, and the presence and location of phosphoryl guanidine groups in the primer. …”
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864
The Role of Ubiquitin-Like Interferon (IFN)-Stimulated 15 and IFN Gamma Genes Polymorphism with the Severity and Serum Biochemical Markers in COVID-19 Patients
Published 2024-12-01“…Objectives: This study examined the relationships between rs1921 and rs1861494 single nucleotide polymorphisms with the manifestation of coronavirus disease 2019 (COVID-19) symptoms in patients and the status of biochemical markers in previously diagnosed cases. …”
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865
Eilat virus isolated from Culex univittatus mosquitoes from the Namibian Zambezi Region influences in vitro superinfection with alpha- and flaviviruses in a virus-species-dependent...
Published 2024-01-01“…Full genome analysis of MP458-NA-2018 showed 94.5% nucleotide identity to an EILV isolate from Israel. …”
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866
Prevalence, Molecular Epidemiology, and Clinical Characteristics of Human Bocavirus Among Patients with Acute Gastroenteritis in Northern Brazil During 2017–2022
Published 2025-01-01“…PCR and nested-PCR were employed to detect HBoV, followed by nucleotide sequencing to identify viral types. Out of 692 samples, HBoV positivity was detected in 9.2% of cases (64/692). …”
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867
Detection and Whole-Genome Characteristics of <i>Bordetella trematum</i> Isolated from Captive Snakes
Published 2025-01-01“…The whole-genome sequencing and comparison with limited public data revealed a high diversity within <i>B. trematum</i>, reaching >48,000 single nucleotide polymorphisms (SNPs), with 64 SNP differentiating tested snake isolates and thus, being considered epidemiologically unrelated. …”
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868
Attenuation and Immunogenicity of a Live High Pathogenic PRRSV Vaccine Candidate with a 32-Amino Acid Deletion in the nsp2 Protein
Published 2014-01-01“…Moreover, there were one nucleotide deletion and a unique 34-amino acid deletion found at 5′UTR and in nsp2 gene during the attenuation process, respectively. …”
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869
ADIPOQ rs2241766 Gene Polymorphism and Predisposition to Diabetic Kidney Disease
Published 2020-01-01“…This meta-analysis was performed to obtain a more comprehensive estimation of the role of the single nucleotide polymorphism (SNP) rs2241766 in the ADIPOQ gene in the occurrence of diabetic kidney disease (DKD). …”
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870
Short communication: Genomic prediction based on unbiased estimation of the genomic relationship matrix in pigs
Published 2025-02-01“…The simulated dataset encompasses six traits, 900 quantitative trait loci, and 36 000 single nucleotide polymorphisms (SNPs). Two scenarios (small effect genes; major genes and small effect genes) and three heritabilities (0.1, 0.3 and 0.5) were considered. …”
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871
Trajectory of human migration: insights from autosomal and non-autosomal variant clustering patterns
Published 2025-03-01“…Here, we analyzed over 75 million genetic variants (single nucleotide variants (SNVs) and short insertion-deletion (InDels)) within consecutive 2500000 base pair windows in the autosomal as well as non-autosomal chromosomes of 22 populations in four major geographic regions that are cataloged in the 1000 Genomes Project to understand the clustering patterns of the autosomal and non-autosomal variants. …”
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872
Small open reading frames (sORFs): Driving big improvements in plant development and quality
Published 2025-03-01“…Small open reading frames (sORFs) are defined as short nucleotide sequences, typically no longer than 300 base pairs, which have the potential to encode small peptides. …”
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873
Impact of Enzymatic Degradation Treatment on Physicochemical Properties, Antioxidant Capacity, and Prebiotic Activity of Lilium Polysaccharides
Published 2025-01-01“…Importantly, with the reduction in molecular weight, G-LPS(16) also particularly stimulated sphingolipid metabolism, nucleotide metabolism, as well as ascorbic acid and uronic acid metabolism, leading to the significant increase in specific metabolites such as sphingosine. …”
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874
Testing and identification of bovine viral diarrhea virus isolates recovered in Russia between 2019 and 2022
Published 2023-12-01“…Based on the analysis of the nucleotide sequence of genome 5’-untranslated region (5’-UTR) fragment, these isolates were classified as belonging to three genotypes of the virus. …”
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875
X-Linked Lymphoproliferative Syndrome and Common Variable Immunodeficiency May Not Be Differentiated by SH2D1A and XIAP/BIRC4 Genes Sequence Analysis
Published 2011-01-01“…XIAP/BIRC4 sequencing revealed two novel single nucleotide variants (exon 7, 1978G > A, and 1996T > A) in the 3′UTR of the gene in both patient and mother which were not disease causing. …”
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876
Complete Mitochondrial Genome of <i>Niphon spinosus</i> (Perciformes: Niphonidae): Genome Characterization and Phylogenetic Analysis
Published 2025-01-01“…The H-strand encoded 28 genes (14 tRNA, 2 rRNA, and 12 PCGs), and D-loop, whereas the L-strand encoded the remaining 9 genes (8 tRNA and <i>ND6</i>). Its nucleotide composition, gene arrangement, codon usage patterns, and tRNA secondary structures are identical with other members of the Percoidei suborder. …”
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877
Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL
Published 2015-01-01“…The online expression quantitative trait loci database was searched for trans-expression single nucleotide polymorphisms (trans-eSNPs) of ATG5. Tagging trans-eSNPs were genotyped by a custom-made genotyping chip in 280 patients and 199 controls. …”
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878
Pleiotropic Associations of RARRES2 Gene Variants and Circulating Chemerin Levels: Potential Roles of Chemerin Involved in the Metabolic and Inflammation-Related Diseases
Published 2018-01-01“…Clinical and metabolic phenotypes, 13 inflammatory markers, 5 adipokines, and 6 single-nucleotide polymorphisms (SNPs) covering the RARRES2 region were analyzed. …”
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879
Genetic polymorphisms and related risk factors of ischemic stroke in a Mongolian population in China
Published 2017-11-01“…The association was detected with single nucleotide polymorphisms (SNPs) located within genes NINJ2 (rs12425791) and ALDH2 (rs2238151) as well as intergenic rs9536591 were significantly associated with ischemic stroke, of which SNP rs12425791 of the NINJ2 gene was the strongest association. …”
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880
Genome-wide association study of myofiber type composition traits in a yellow-feather broiler population
Published 2025-01-01“…We identified 1 and 18 single-nucleotide polymorphisms (SNPs) significantly and potentially associated with the proportion of slow muscle fibers, respectively, and 1 and 12 SNPs significantly and potentially associated with the area proportion of slow muscle fibers, respectively. …”
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