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721
Pyruvic Oxime Nitrification and Copper and Nickel Resistance by a Cupriavidus pauculus, an Active Heterotrophic Nitrifier-Denitrifier
Published 2014-01-01“…Neither N2 nor N2O were produced. Nucleotide and phylogenetic analyses indicated that the organism is a member of a genus (Cupriavidus) known for its resistance to metals and its metabolism of xenobiotics. …”
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722
The Development of a One-Step PCR Assay for Rapid Detection of an Attenuated Vaccine Strain of Duck Hepatitis Virus Type 3 in Korea
Published 2024-12-01“…The method was specifically designed to target the critical single-nucleotide polymorphism (SNP) site (T→C at position 1143 in the VP0 gene) unique to the Korean vaccine strain AP04203-P100. …”
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723
Genetic Variations of Cytokines and Cytokine Receptors in Psoriasis Patients from China
Published 2014-01-01“…We genotyped seven single-nucleotide polymorphisms (SNPs) in candidate genes of six ILs: IL4, IL10, IL12B, IL13, IL15, and IL23R, which have been shown in the literature to be associated with psoriasis in other ethnic groups. …”
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724
Detection and Genetic Analysis of Porcine Bocavirus in Different Swine Herds in North Central China
Published 2014-01-01“…All PBoV sequenced in this study belong to PBoV-a–PBoV-d with 90.1% to 99% nucleotide identities. Our results exhibited significant genetic diversity of PBoV and suggested a complex prevalence of PBoV in Chinese swine herds. …”
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725
Structural insights on anti-biofilm mechanism of heated slightly acidic electrolyzed water technology against multi-resistant Staphylococcus aureus biofilm on food contact surface
Published 2024-05-01“…Moreover, signaling pathways involved in amino acid metabolism, energy metabolism, nucleotide synthesis, carbohydrate metabolites, and lipid biosynthesis were functionally disrupted by the SAEW at 40 ℃ treatment. …”
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726
Genetic Variation in Taste Receptor Genes (SCNN1B, TRPV1) and Its Correlation with the Perception of Saltiness in Normotensive and Hypertensive Adults
Published 2021-01-01“…The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) in the salt taste receptor genes SCNN1B and TRPV1 affect salt taste perception among normotensive and hypertensive people. …”
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727
Neurotropic Tick-Borne Flavivirus in Alpine Chamois (<i>Rupicapra rupicapra rupicapra</i>), Austria, 2017, Italy, 2023
Published 2025-01-01“…The virus strains exhibit 94.8–97.3% nucleotide identities to each other and are more closely related to Louping ill viruses (LIV; <i>Orthoflavivirus loupingi</i>; 90–92% identities) than to TBEV-Eur (less than 88%). …”
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728
Comparative analysis of mitochondrial genomes from Buthidae (Scorpiones): gene rearrangement and phylogenetic implications
Published 2025-01-01“…These five mitogenomes had a typical circular structure, with total sizes ranging from 14,504 to 15,083 bp. Nucleotide composition analysis indicated that the sequences were biased toward A and T. …”
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729
Improvements in pig agriculture through gene editing
Published 2022-06-01“…The availability of genome editing tools that allow for the introduction of precise genetic modification at a single nucleotide resolution, while also facilitating large transgene integration in the target population, offers a solution. …”
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730
Research note: A low-density SNP genotyping panel for Chinese native chickens
Published 2025-01-01“…In the present study, we developed a chicken 11 K single nucleotide polymorphism (SNP) genotyping panel for breeding and genetic analysis using genotyping by targeted sequencing (GBTS). …”
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731
Novel Graphical Analyses of Runs of Homozygosity among Species and Livestock Breeds
Published 2016-01-01“…We used genomic profiles based on 698 K single nucleotide polymorphisms (SNPs) from nine breeds of domestic cattle (Bos taurus) and the European bison (Bison bonasus) to investigate how ROH distributions can be compared within and among species. …”
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732
Genetics of Myasthenia Gravis: A Case-Control Association Study in the Hellenic Population
Published 2012-01-01“…A statistical trend of association (P=0.068) between IL-10 promoter single nucleotide polymorphisms (SNPs) and the subgroups of early and late-onset MG patients was revealed. …”
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733
Association Analysis of Polymorphisms with Aspirin-Exacerbated Respiratory Disease in a Korean Population
Published 2014-06-01“…We genotyped 38 TEC single nucleotide polymorphisms in a total of 592 subjects, which comprised 163 AERD cases and 429 aspirin-tolerant asthma controls. …”
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734
The known genetic variants of BRCA1, BRCA2 and NOD2 in pancreatitis and pancreatic cancer risk assessment
Published 2025-01-01“…Abstract The single nucleotide polymorphism in NOD2 (rs2066847) is associated with conditions that may predispose to the development of gastrointestinal disorders, as well as the known BRCA1 and BRCA2 variants classified as risk factors in many cancers. …”
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735
A recent large-scale intraspecific IR expansion and evolutionary dynamics of the plastome of Peucedanum japonicum
Published 2025-01-01“…A total of nine single nucleotide polymorphisms and eight insertions or deletions were identified among the five L-type plastomes, whereas large variations were identified among the five S-type plastomes. …”
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736
DNA-mediated self-assembly oxidative damage amplifier combined with copper and MTH1 inhibitor for cancer therapy
Published 2025-03-01“…However, the efficiency of CDT is severely hampered by the massive presence of glutathione (GSH) in tumor cells and the interference of ROS defense systems, such as Mutt homolog 1 (MTH1) protein sanitizes ROS-oxidized nucleotide pools. In this research, DNA-mediated self-assembly nanoparticles (HTCG@TA NPs) were engineered with high-performance amplified oxidative damage and gene therapy effect for synergistic anti-tumor treatment. …”
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737
Rationale and design of a prospective study evaluating population pharmacokinetics and pharmacodynamics of rivaroxaban in Chinese patients with non-valvular atrial fibrillation
Published 2022-06-01“…Rivaroxaban plasma concentration, factor Xa activity, prothrombin time and single-nucleotide polymorphisms of candidate genes will be evaluated. …”
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738
Xeroderma Pigmentosum with Severe Neurological Manifestations/De Sanctis–Cacchione Syndrome and a Novel XPC Mutation
Published 2017-01-01“…Several genetic disorders caused by defective nucleotide excision repair that affect the skin and the nervous system have been described, including Xeroderma Pigmentosum (XP), De Sanctis–Cacchione syndrome (DSC), Cockayne syndrome, and Trichothiodystrophy. …”
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739
The effects of runs-of-homozygosity on pig domestication and breeding
Published 2025-01-01“…Results Here we integrated a comprehensive dataset comprising 7239 domesticated pigs and wild boars genotyped by single nucleotide polymorphism (SNP) chips, along with phenotypic data encompassing growth, reproduction and disease-associated traits. …”
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740
Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt
Published 2015-01-01“…A selected panel of single nucleotide polymorphisms (SNPs) associated with susceptibility was studied to verify if there was association with poor prognosis. …”
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