Metabolomics reveals the effect of vacuum packaging combined with moderate-temperature preservation on quality changes of tender ginger by Ying-Ying Jing, Fan-Bing Meng, Zhen-Yu Peng, Qing-Zhou Li, Ya-Ting Lei, Yun-Cheng Li

“…The characteristic metabolites were primarily associated with amino acid, lipid and nucleotide metabolism. The metabolic pathways mainly involved linoleic acid metabolism; alanine, aspartate and glutamate metabolism; and purine metabolism. …”
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Using Genome-Wide SNP Discovery and Genotyping to Reveal the Main Source of Population Differentiation in Nothofagus dombeyi (Mirb.) Oerst. in Chile by Rodrigo Hasbún, Jorge González, Carolina Iturra, Glenda Fuentes, Diego Alarcón, Eduardo Ruiz

“…The study of demographic and selection histories in Nothofagus dombeyi requires more informative markers such as single nucleotide polymorphisms (SNP). Genotyping-by-Sequencing tools now allow studying thousands of SNP markers at reasonable prices in nonmodel species. …”
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Live Plague Vaccine Development: Past, Present, and Future by Andrey P. Anisimov, Anastasia S. Vagaiskaya, Alexandra S. Trunyakova, Svetlana V. Dentovskaya

“…In this review, we present our opinion on reasonable tactics for the development and application of live, safe, and protective human plague vaccines causing an enhanced duration of protection and breadth of action against various virulent strains in vaccination studies representing different ages, genders, and nucleotide polymorphisms of the genes responsible for immune response.…”
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GATA4 binding to the Sox9 enhancer mXYSRa/Enh13 is critical for testis differentiation in mouse by Yuya Ogawa, Iku Tsuchiya, Shogo Yanai, Takashi Baba, Ken-Ichirou Morohashi, Takehiko Sasaki, Junko Sasaki, Miho Terao, Atsumi Tsuji-Hosokawa, Shuji Takada

“…This study identified an additional functional sequence by generating mice with partial deletions in mXYSRa/Enh13. Two nucleotide substitutions within the sequence were sufficient for male-to-female sex reversal. …”
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Robust and inducible genome editing via an all-in-one prime editor in human pluripotent stem cells by Youjun Wu, Aaron Zhong, Mega Sidharta, Tae Wan Kim, Bernny Ramirez, Benjamin Persily, Lorenz Studer, Ting Zhou

“…Abstract Prime editing (PE) allows for precise genome editing in human pluripotent stem cells (hPSCs), such as introducing single nucleotide modifications, small insertions or deletions at a specific genomic locus. …”
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Monitoring for respiratory viruses among wild canids, Texas by Lyudmyla V. Marushchak, Laura A. Pulscher, Judith U. Oguzie, Diego B. Silva, Kenneth A. Waldrup, Douglas M. Watts, Gregory C. Gray

“…We used virus molecular techniques, culture and next-generation nucleotide sequencing to search for and characterize viruses in the Coronaviridae and Orthomyxoviridae families. …”
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Research note: Genetically diverse avian hepatitis E virus identified in chickens with hepatitis-splenomegaly syndrome in Guangdong Province, China by Xue-Lian Zhang, Yu-Qian Zhang, Chun-Hong Liu, Yan Ma, Shu-Jian Huang, Jian-Wei Shao

“…Sequence analysis indicated that these strains shared the highest nucleotide sequence identities with genotype 3 strains, and phylogenetic analysis demonstrated that they clustered with strains belonging to avian HEV genotype 3. …”
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Toxicity and Molecular Identification of Green Toadfish Lagocephalus lunaris Collected from Kyushu Coast, Japan by Yuji Nagashima, Takuya Matsumoto, Keisuke Kadoyama, Shoichiro Ishizaki, Makoto Terayama

“…Liquid chromatography/mass spectrometry analysis revealed that TTX was the major toxin. Nucleotide sequence analysis of the 16S rRNA gene fragment of muscle mitochondrial DNA indicated that partial sequences of PCR products of four specimens were identical with that of L. lunaris. …”
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Structural basis for the transport and regulation mechanism of the multidrug resistance-associated protein 2 by Eriko Koide, Harlan L. Pietz, Jean Beltran, Jue Chen

“…In the autoinhibited state, the cytosolic regulatory (R) domain plugs into the transmembrane substrate-binding site and extends into the cytosol to form a composite ATP-binding site at the surface of nucleotide-binding domain 2. Substrate displaces the R domain, permitting conformational changes necessary for transport. …”
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An Update on the Management of Chronic Hepatitis C: Consensus Guidelines from the Canadian Association for the Study of the Liver by Robert P Myers, Alnoor Ramji, Marc Bilodeau, Stephen Wong, Jordan J Feld

“…Specifically, direct-acting antiviral agents with dramatically improved rates of virological clearance compared with standard therapy have been developed, and several single nucleotide polymorphisms associated with an increased probability of spontaneous and treatment-induced viral clearance have been identified. …”
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Genetic Variants in SNCA and the Risk of Sporadic Parkinson’s Disease and Clinical Outcomes: A Review by Clarissa Loureiro das Chagas Campêlo, Regina Helena Silva

“…Positive associations of single nucleotide polymorphisms (SNPs) in SNCA and increased risk for PD were found. …”
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Genetic Risk Factors for Metabolic Dysfunction-Associated Steatotic Liver Disease by Yiying Pei, George Boon-Bee Goh

“…Notably, the PNPLA3, TM6SF2, GCKR, MBOAT7 and HSD17B13 single nucleotide polymorphisms have been demonstrated to be robustly associated with MASLD development and disease progression. …”
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Comparison and analysis of phylogenetic relationship based on internal transcribed spacer 1, its-1 fragment of eimeria tenella and eimeria acervulina from broiler chicken in korea by Myung-Jo You

“…<p> <b>Results:</b> About the 273-bp and 147-bp sequence of ITS-1 of E. tenella and E. acervulina in Korea were similar reflected in the phylogram constructed using the partial nucleotide sequences. In case of E. tenella for homology searching the sequences among the same species was 98% and with E. necatrix was 89%. …”
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Plant Growth Promoting of Endophytic Sporosarcina aquimarina SjAM16103 Isolated from the Pneumatophores of Avicennia marina L. by S. Rylo Sona Janarthine, P. Eganathan

“…Endophytic S. aquimarina SjAM16103 was Gram variable, and motile bacterium measured 0.6–0.9 μm wide by 1.7–2.0 μm long and light orange-brown coloured in 3-day cultures on tryptone broth at 26°C. Nucleotide sequence of this strain has been deposited in the GenBank under accession number GU930359. …”
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STUDY OF Bacillus licheniformis BACTERIA AS A BIO-CONTROL AGENT IN REDUCING AFLATOXIN B1 TOXICITY IN DRIED GRAPE SAMPLES by H. Z. Hussein, E. K. Abdul-Karim, M. I. Alghannoum

“…The isolate with the highest toxin production was identified through nucleotide sequences deposited in the World Genomic Organization's Gene Bank under accession number OR192858. …”
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Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside by Rajeshwari D. Koilkonda, John Guy

“…These mutations are located at nucleotide positions 3460, 11778, or 14484 in the mitochondrial genome. …”
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Diversity of Mycobacterium tuberculosis Complex Lineages Associated with Pulmonary Tuberculosis in Southwestern, Uganda by Lisa, Nkatha Micheni, Kennedy, Kassaza, Hellen, W. Kinyi

“…A total of 283 sputum samples from patients with pulmonary tuberculosis were genotyped using specific single nucleotide polymorphism markers for lineages 3 and 4. …”
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Traceback and Testing of Food Epidemiologically Linked to a Norovirus Outbreak at a Wedding Reception by Efstathia Papafragkou, Amanda Kita-Yarbro, Zihui Yang, Preeti Chhabra, Timothy Davis, James Blackmore, Courtney Ziemer, Rachel Klos, Aron J. Hall, Jan Vinjé

“…Norovirus-positive clinical samples (n = 4) were genotyped as GII.4 Sydney and norovirus-positive fruit salad samples (n = 2) confirmed the presence of GII.4 norovirus by Sanger sequencing with 98% nucleotide (n = 236) similarity in 5′ end of ORF2 between fruit salad and clinical specimens. …”
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The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response by Thomas Daniel Kraemer, Orlando Daniel Quintanar Haro, Eugen Domann, Trinad Chakraborty, Svetlin Tchatalbachev

“…Screening of E. faecalis samples revealed that tcpF is more common in isolates from urinary tract infections (UTIs) than in human faecal flora. tcpF alleles showed moderate single nucleotide polymorphism (SNP) among UTI isolates. Infection of mouse RAW264.7 macrophages with a tcpF knock-out mutant led to elevated cytokine response compared to the isogenic wild type E. faecalis strain. …”
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Influence of Genetic Variants of the N-Methyl-D-Aspartate Receptor on Emotion and Social Behavior in Adolescents by Li-Ching Lee, Ying-Chun Cho, Pei-Jung Lin, Ting-Chi Yeh, Chun-Yen Chang, Ting-Kuang Yeh

“…This exploratory study examined the relationship of single-nucleotide polymorphism (SNP) variations in the genes encoding the NMDA receptor (i.e., GRIN1, GRIN2A, GRIN2B, GRIN2C, and GRIN2D) with emotion and social behavior in adolescents. …”
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