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501
INFORMACINIS GENOMAS, INDIVIDO IR POPULIACIJOS GENOMAI
Published 2002-01-01“…In the DNA millions of nucleotide long molecule there is encoded cellular, organism and population information. …”
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502
An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice.
Published 2013-01-01“…Thus, there is a pressing need for non-nucleotide antiviral agent from traditional source. …”
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503
Global metabolomic profiling of tumor tissue and paired serum samples to identify biomarkers for response to neoadjuvant FOLFIRINOX treatment of human pancreatic cancer
Published 2025-02-01“…In general, DAMs associated with amino acid and nucleotide metabolism were lower in NAT compared to TN. …”
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504
New insights into the structure domain and function of NLR family CARD domain containing 5
Published 2025-01-01“…NLRC5 is the largest member of the NLR family and contains three domains: an untypical caspase recruitment domain (uCARD), a central nucleotide-binding and oligomerization domain (NOD or NACHT), and a leucine-rich repeat (LRR) domain. …”
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505
GENOME-WIDE SNP ALLELOTYPING OF HUMAN COHORTS BY POOLED DNA SAMPLES
Published 2015-01-01“…The research concerns the task of identification of contrasted single nucleotide polymorphisms (SNPs) obtained in genome-wide pooled allelotyping of 16 human cohorts, comprising healthy and ill persons, by the nested case–control approach. …”
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506
Molecular Mechanisms of the Whole DNA Repair System: A Comparison of Bacterial and Eukaryotic Systems
Published 2010-01-01“…A variety of different DNA repair pathways have been reported: direct reversal, base excision repair, nucleotide excision repair, mismatch repair, and recombination repair pathways. …”
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507
First mitochondrial genome of Lutjanus ehrenbergii_ Peters 1869 (Lutjaniformes: Lutjanidae: Lutjanus) and phylogenetic analysis
Published 2025-01-01“…All of the protein-encoding genes were located on the H chain except ND6. The nucleotide composition was A (28.04%), T (24.84%), C (30.89%) and G (16.23%). …”
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508
High-coverage whole-genome sequencing of a Jakun individual from the “Orang Asli” Proto-Malay subtribe from Peninsular Malaysia
Published 2025-01-01“…We identified approximately 3.6 million single-nucleotide variations (SNVs) and 517,784 small insertions/deletions (indels). …”
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509
Importance of OsRac1 in Signalling of Pigm-1 Mediated Resistance to Rice Blast Disease
Published 2025-01-01“…In rice, leucine-rich repeat nucleotide-binding site (NLR) proteins are pivotal immune receptors in combating <i>Magnaporthe oryzae</i>-triggered rice blast. …”
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510
Efficiency of using SNP markers in the <i>MSTN</i> gene in the selection of the Pushkin breed chickens
Published 2020-01-01“…It was based on selection for single nucleotide polymorphism rs313744840 in the MSTN gene. …”
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511
Three new asexual Kirschsteiniothelia species from Guizhou Province, China
Published 2025-02-01“…Furthermore, the effectiveness of three DNA markers for species-level identification within Kirschsteiniothelia was evaluated using Assemble Species by Automatic Partitioning (ASAP) analysis, which identified the ITS nucleotide sequences as the most reliable marker for species differentiation within the genus.…”
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512
Application of Whole Exome Sequencing to Identify Disease-Causing Variants in Inherited Human Diseases
Published 2012-12-01“…Human genetics is no exception-it has never been easier to interrogate human patient genomes at the nucleotide level to identify disease-associated variants. …”
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513
Relationships between genomic dissipation and de novo SNP evolution.
Published 2024-01-01“…Patterns of single nucleotide polymorphisms (SNPs) in eukaryotic DNA are traditionally attributed to selective pressure, drift, identity descent, or related factors-without accounting for ways in which bias during de novo SNP formation, itself, might contribute. …”
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514
Successful Treatment of Adenovirus Infection with Brincidofovir in an Immunocompromised Patient after Hematological Stem Cell Transplantation
Published 2020-01-01“…Our case describes the successful use of Brincidofovir (CMX001), a lipid-conjugate of the nucleotide analog Cidofovir, in a 9-year-old post-HSCT girl with disseminated adenovirus infection. …”
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515
A High Resolution Melting Analysis (HRM) PCR assay for the detection and identification of Old World Leishmania species.
Published 2024-12-01“…Differentiation was achievable with as little as a single nucleotide difference occurring within or between species. …”
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516
Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats
Published 2025-01-01“…Metabolomics results showed that the potential metabolic pathways of YXRJP in the treatment of DPN mainly involved amino acid metabolism such as arginine, alanine, aspartic acid, lipid metabolism and nucleotide metabolism.Conclusion: YXRJP can effectively improve the symptoms of DPN rats and reduce nerve damage. …”
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517
ANALYSIS OF GENETIC CHARACTERISTICS OF INFLUENZA VIRUS A/CHICKEN/CHELYABINSK/30/2019 H9N2 ISOLATED IN CHELYABINSK OBLAST
Published 2019-12-01“…The complete nucleotide genome sequence of the studied pathogen was determined. …”
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518
Prevalence and Molecular Characterization of Cysticercus tenuicollis Isolated from Some Intermediate Host in Kurdistan-Iraq
Published 2018-09-01“…This result shows no significant differences of C. tenuicollis between sheep and goats (p>0.05). The nucleotide sequence alignment of cytochrome oxidase subunit 1 (CO 1) gene revealed that the amplified DNA fragment is belong to Taenia hydatigena and Echinococcus granulosus and the nucleotide sequences of T. hydatigena deposited in GenBank under accession number (MH638348). …”
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519
Newcastle disease virus genotype VII.1.1 identified from backyard chickens with low antibody titer: Jimma Zone, Southwest Ethiopia.
Published 2025-01-01“…Further, positive swab samples were nucleotide sequenced and genotyped. Results Of the 90 serum samples, 62 (68.8%) were seropositive. …”
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520
Identification of Parkinson’s disease using MRI and genetic data from the PPMI cohort: an improved machine learning fusion approach
Published 2025-02-01“…ObjectiveThis study aim to leverage advanced machine learning techniques to develop and validate novel MRI imaging features and single nucleotide polymorphism (SNP) gene data fusion methodologies to enhance the early identification and diagnosis of Parkinson’s disease (PD).MethodsWe leveraged a comprehensive dataset from the Parkinson’s Progression Markers Initiative (PPMI), which includes high-resolution neuroimaging data, genetic single-nucleotide polymorphism (SNP) profiles, and detailed clinical information from individuals with early-stage PD and healthy controls. …”
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