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461
Plasmidome of Salmonella enterica serovar Infantis recovered from surface waters in a major agricultural region for leafy greens in California.
Published 2024-01-01“…In addition, a second 4-kb plasmid was detected in two strains. Plasmid nucleotide queries did not identify the emerging megaplasmid pESI in the examined Infantis strains; however, the detected plasmids each had similarity to a plasmid sequence already cataloged in the nucleotide databases. …”
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462
PYROSEQUENCING: ITS POTENTIAL AND LIMITATIONS IN DIAGNOSIS OF INHERITED DISEASES IN CATTLE
Published 2019-12-01“…DNA pyrosequencing, being the most convenient technique for the rapid diagnosis of single nucleotide mutations in the bovine genome that are located in the regions with known nucleotide sequence, has a potential for meeting this need. …”
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463
Genetic Association Analysis of Fasting and 1- and 2-Hour Glucose Tolerance Test Data Using a Generalized Index of Dissimilarity Measure for the Korean Population
Published 2016-12-01“…One pair (rs2328549 and rs6486740) has a prominent association, where the two single-nucleotide polymorphism locations are CDKAL1 and GLT1D1. …”
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464
Microcephalic osteodysplastic primordial dwarfism type II in four Indian children with PCNT variants
Published 2025-01-01“…Two mutations, a nonsense c.5299C > T and a frameshift single nucleotide deletion c.4180delG are currently mentioned in few databases only. …”
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465
Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle.
Published 2023-05-01“…Hch1 appears to destabilize Hsp90-nucleotide interaction, hindering formation of the closed conformation, whereas Cpr6 counters the effects of Hch1 by stabilizing the closed conformation. …”
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466
Identifying unstable CNG repeat loci in the human genome: a heuristic approach and implications for neurological disorders
Published 2024-06-01“…Abstract Tandem nucleotide repeat (TNR) expansions, particularly the CNG nucleotide configuration, are associated with a variety of neurodegenerative disorders. …”
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467
Polymorphism of the rps16 gene intron in Malus Mill. and related Rosaceae Juss. species
Published 2017-11-01“…Nucleotide sequences of the rps16 chloroplast gene group II intron from 32 Malus species and 17 related Rosaceae species were amplified, sequenced and their polymorphism was analyzed. …”
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468
Studyof resistance of pathogenic and opportunistic fungi toantimycotics
Published 2022-03-01“…The analysis of gene ERG11 nucleotide sequences of 10 Candida albicans isolates, recovered from different animal species, enabled the division of phenotypically resistant and susceptible strains, but could not differentiate between the strains, which have dose-dependent resistance to azoles. …”
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469
Association between BAFF gene polymorphism and systemic lupus erythematosus: a meta-analysis
Published 2024-12-01“…Abstract Objective To inquire into the association from BAFF gene promoter -871C > T single nucleotide polymorphisms (SNP) to the etiopathogenesis of systemic lupus erythematosus (SLE) and to further discuss the interracial differences through ethnostratified methods. …”
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470
A Survey of Wild Indigenous <i>Cryptostylis ovata</i> Orchid Populations in Western Australia Reveals Spillover of Exotic Viruses
Published 2025-01-01“…The OrMV isolate shared 98–99% nucleotide identity with isolates identified from wild indigenous <i>Lachenalia</i> (Iridaceae) plants in South Africa. …”
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471
BIOINFORMATIC ANALYSIS OF THE GENOME OF THE Geobacillus stearothermophilus 22 STRAIN ISOLATED FROM THE GARGA HOT SPRING, BAIKAL REGION
Published 2015-01-01“…The sequence was subjected to bioinformatic analysis. Nucleotide sequences (contigs) of the strain were found to be similar to the genome of the thermophilic strain G. kaustophilus Y412MC52. …”
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472
Genetic diversity and population structure studies of West African sweetpotato [Ipomoea batatas (L.) Lam] collection using DArTseq.
Published 2025-01-01“…<h4>Results</h4>29,523 Diversity Arrays Technology (DArTseq) single nucleotide polymorphism markers were used to genotype 271 sweetpotato accessions. …”
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473
AGS3-based optogenetic GDI induces GPCR-independent Gβγ signalling and macrophage migration
Published 2025-02-01“…G-protein-coupled receptors (GPCRs) are efficient guanine nucleotide exchange factors (GEFs) and exchange GDP to GTP on the Gα subunit of G-protein heterotrimers in response to various extracellular stimuli, including neurotransmitters and light. …”
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474
Infectious bursal disease virus: identification of the novel genetic group and reassortant viruses
Published 2022-03-01“…The results of the phylogenic analysis of the nucleotide sequence of the IBDV A and B genome segments have been presented. …”
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475
Peste Des Petits Ruminants (PPR) in Dromedary Camels and Small Ruminants in Mandera and Wajir Counties of Kenya
Published 2019-01-01“…The analysis of sequences revealed closest nucleotide identities of obtained sequences from both goat and camel to the lineage III of PPRV albeit with 60.29% of nucleotide identity. …”
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476
Leveraging Next-Generation Sequencing Application from Identity to Purity Profiling of Nucleic Acid-Based Products
Published 2024-12-01“…<b>Results</b>: Our workflow predicted most of the critical quality controls of mRNA vaccine and plasmid DNA samples, especially focusing on the identity and the nucleotide-based impurities. Additionally, NGS data interpretation also assisted in strategic decisions for NAP manufacturing process optimizations. …”
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477
Novel frameshift variant of WNT10A in a Japanese patient with hypodontia
Published 2024-01-01“…Exome sequencing, followed by Sanger sequencing, identified a novel single-nucleotide deletion in WNT10A (NC_000002.12(NM_025216.3):c.802del), which was not found in the healthy parents of the patient. …”
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478
IMPLEMENTATION OF 454 LIFE SCIENCES TECHNOLOGY LABORATORY PRACTICES
Published 2018-04-01“…He article demonstrates possibility of using highly productive pyrophosphate sequencing, also known as 454 Life Sciences technology for investigation of highly variable and understudied infectious viral agents. Genome-wide nucleotide sequences of infectious bronchitis virus, infectious laryngotracheitis virus, fowl adenovirus C, and avian adenoassociated virus were determined. …”
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479
PHYLOGENETIC RELATIONSHIPS AMONG SEVERAL NORTH-ASIAN SPECIES OF THE GENUS AQUILEGIA ACCORDING TO VARIOUS MOLECULAR MARKERS
Published 2015-01-01“…Molecular study of the nucleotide sequence of the rpl32-trnL spacer and the ITS1-ITS2 fragment of rRNA genes in eight species of the genus Aquilegia sampled in Northern Asia has shown that populations of A. borodinii and A. jucunda from various localities are genetically diverse. …”
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480
Formulation and Analysis of Patterns in a Score Matrix for Global Sequence Alignment
Published 2020-01-01“…Global sequence alignment is one of the most basic pairwise sequence alignment procedures used in molecular biology to understand the similarity that arises among the structure, function, or evolutionary relationship between two nucleotide sequences. The general algorithm associated with global sequence alignment is the dynamic programming algorithm of Needleman and Wunsch. …”
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