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361
Oxidative stress and dysregulated long noncoding RNAs in the pathogenesis of Parkinson’s disease
Published 2025-01-01“…Long noncoding RNAs (lncRNAs), which are more than 200 nucleotides in length, are also involved in the pathogenesis of PD at the transcriptional level via epigenetic regulation, or at the post-transcriptional level by participating in physiological processes, including aggregation of the α-synuclein, mitochondrial dysfunction, oxidative stress, calcium stabilization, and neuroinflammation. …”
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362
On the space of SARS-CoV-2 genetic sequence variants
Published 2023-12-01“…We have developed software capable of loading and analyzing SARS-CoV-2 nucleotide sequences in FASTA format, determining the 5’ and 3’ UTR positions, the number and location of unidentified nucleotides (“N”), performing alignment with the reference sequence by calling the program designed for this, determining mutations, deletions and insertions, as well as calculating various characteris tics of virus genomes with a given time step (days, weeks, months, etc.). …”
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363
Characterizations of cytokines and viral genomes in serum of patients with Dabie bandavirus infection
Published 2025-01-01“…SZ03-TXF was a recombinant strain with the location of possible breakpoints at nucleotides 795 and 1,432 in the CDS region of the L segment.ConclusionA recombination event was identified in SZ03-TXF strain. …”
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364
The Adducts Lipid Peroxidation Products with 2′-DeoxyNucleosides: A Theoretical Approach of Ionisation Potential
Published 2025-01-01“…The electronic properties analysis of 2′-deoxynucleoside adducts with lipid peroxidation products reveals their potential influence on the cells’ antioxidant pool, whereby they can affect the communication process between proteins, lipids, and nucleotides.…”
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365
Genetics polymorphism of poplars from Moscow region based on high-throughput sequencing of ITS
Published 2018-08-01“…For some sites with SNPs, several variants of nucleotides were found in the same individual and the ratio of SNPs was different. …”
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366
Application of the weighted histogram method for calculating the thermodynamic parameters of the formation of oligodeoxyribonucleotide duplexes
Published 2023-12-01“…The feasibility of calculation of ∆H°, ∆S°, and ∆G37° was demonstrated using a representative sample of 21 oligonucleotides 4–16 nucleotides long with a GC content of 14–100 %. Error of the calculation of the thermodynamic parameters was 11.4, 12.9, and 11.8 % for ∆H°, ∆S°, and ∆G37° , respectively, and the melting temperature was predicted with an average error of 5.5 °C. …”
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367
The study of organelle DNA variability in alloplasmic barley lines in the NGS era
Published 2020-03-01“…The nonsynonymous changes of nucleotides were detected in the matK, rpoCI, ndhK, ndhG and infA genes. …”
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368
Establishing a GRU-GCN coordination-based prediction model for miRNA-disease associations
Published 2025-01-01“…Abstract Background miRNAs (microRNAs) are endogenous RNAs with lengths of 18 to 24 nucleotides and play critical roles in gene regulation and disease progression. …”
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369
Biochemistry of the Thrombin-Like TLBpic and Its Purification from Bothrops pictus “Jergon de la Costa” (Reptilia: Viperidae)
Published 2019-01-01“…Within the simple substances, we have free amino acids, peptides, nucleotides, carbohydrates, lipids, and biogenic amines (organic molecules) as well as cations and anions (inorganic constituents). …”
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370
Biochemistry /
Published 2011Table of Contents: “…Carbohydrates, lipids, and amino acids : metabolic fuels and biosynthetic precursors -- Proteins and enzymes -- Membrane biochemistry and signal transduction -- Nutrition -- Generation of energy from dietary fuels -- Carbohydrate metabolism -- Lipid metabolism -- Nitrogen metabolism -- Integration of metabolism -- Nucleotide synthesis and metabolism -- Organization, synthesis, and repair of DNA -- Gene expression -- DNA technology -- Common laboratory values.…”
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371
Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids
Published 2025-02-01“…Whole exome sequencing revealed that over 99% of single nucleotides were shared between the NO and matched BO and there was a 95% overlap in their RNA transcriptomes. …”
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372
Sequence Variation in Toxoplasma gondii rop17 Gene among Strains from Different Hosts and Geographical Locations
Published 2014-01-01“…Sequence analysis identified 33 variable nucleotide positions (2.1%), 16 of which were identified as transitions. …”
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373
Hiperurisemia pada Pra Diabetes
Published 2012-09-01“…<br />Kata kunci: Hiperurisemia, Pra Diabetes<br />Abstract<br />Uric acid (AU) is the end product of the catabolism of adenine and guanine nucleotides derived from the<br />breakdown of purines. …”
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374
Immunonutrition for traumatic brain injury in children and adolescents: protocol for a systematic review and meta-analysis
Published 2020-09-01“…Immune-enhancing nutrition or immunonutrition, referring to the addition of specialised nutrients, including glutamine, alanine, omega-3 fatty acids and nucleotides, to standard nutrition formulas, may improve surgical outcomes in the perioperative period. …”
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375
SGCL-LncLoc: An Interpretable Deep Learning Model for Improving lncRNA Subcellular Localization Prediction with Supervised Graph Contrastive Learning
Published 2024-09-01“…Additionally, we propose a computational method to map the attention weights of the graph nodes to the weights of nucleotides in the lncRNA sequence, allowing SGCL-LncLoc to serve as an interpretable deep learning model. …”
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376
Microscale total genomic DNA was used to explore the complete mitochondrial genomes of two biting midge species of the family Ceratopogonidae (Insecta: Diptera)
Published 2025-01-01“…F. humilavolita and D. bilineata showed highly conserved mitogenomes, with similar gene orders, 37 typical genes and a noncoding A + T-rich region. The nucleotide composition of these genomes was highly biased towards A + T nucleotides (78.15% and 78.25%), and the AT skews (-0.001894 and 0.011999), negative GC skews (-0.535714 and -0.217391), and codon usage were determined. …”
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377
Molecular Identification and Antimicrobial Potential of Streptomyces Species from Nepalese Soil
Published 2020-01-01“…Here, we have also analyzed 16S rRNA in 27 Streptomyces species whose whole-genome sequence is available, which has revealed that some species have multiple copies of the 16S gene (∼1.5 kb) with significant variation in nucleotides. In contrast, some Streptomyces species shared identical DNA sequences in multiple copies of 16S rRNA. …”
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378
Activity of alkanmonooxygenase <i>alk</i>B gene in strains of hydrocarbon-oxidizing bacteria isolated from petroleum products
Published 2022-10-01“…By real-time PCR using a primer with a different sequence of nucleotides to detect the alkB gene, its activity was established in all bacterial strains isolated from gasoline AI-95; besides, the strain Paenibacillus agaridevorans Bi11 was assigned to the group with a high level of its activity (1290 copies/ml). …”
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379
MicroRNA-21 as a biomarker in terminal stage oral squamous cell carcinoma (OSCC) in the South Indian population
Published 2024-03-01“…They are non-coding sequences with limited no of nucleotides and play important role in regulation of genes. …”
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380
Uncovering genetic determinants of antioxidant properties in Thai landrace rice through genome-wide association analysis
Published 2025-01-01“…GWAS analysis detected 336 quantitative trait nucleotides located at 93 loci, 83% of which were consistently mapped to the reported quantitative trait loci of antioxidant traits. …”
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