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41
Clinical Significance and Characterization of AZT-Resistant Strains of HIV-1
Published 1991-01-01“…In several instances, cross resistance has been observed between AZT and other nucleosides being considered for potential therapy of HIV-1-associated disease.…”
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42
Analysis of the High-Performance Liquid Chromatography Fingerprints and Quantitative Analysis of Multicomponents by Single Marker of Products of Fermented Cordyceps sinensis
Published 2018-01-01“…The relative correction factors (RCF) between adenosine and the other four nucleosides were calculated and investigated using the QAMS method. …”
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43
Development and validation of highly sensitive multiplex real-time RT-PCR assay for detection of classical swine fever virus genome
Published 2024-09-01“…Modified primers (locked nucleic acids containing conformationally blocked nucleosides) providing a higher affinity to the DNA matrix and physico-chemical stability and a FAM-labeled TaqMan probe were selected for 5’-untranslatedregion of the genome. …”
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44
Effects of post-mortem aging process on characteristic water-soluble taste-active precursors in yellow-feathered broilers
Published 2023-01-01“…In order to explore the effect of post-mortem aging on water-soluble flavor precursors of chicken, pH, adenosine triphosphate (ATP) degradation, flavor nucleosides, free amino acids and water-soluble low molecular weight peptides were determined using Qingyuan partridge yellow-feathered broilers as material during 0–4 °C post-mortem aging in 48 h. …”
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45
Decoding oral cancer: insights from miRNA expression profiles and their regulatory targets
Published 2025-01-01“…Functional annotation and pathway enrichment analyses highlighted significant involvement of DEmiRs and their target genes in cell cycle-related processes, including enrichment in the nucleus, transcription factor activity, regulation of nucleosides, nucleotide and nucleic acids, cell growth and/or maintenance, mitotic cell cycle, mitotic M-M/G1 phases an DNA replication. …”
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46
Real-World Analysis of Weight Gain and Body Mass Index Increase Among Patients with HIV-1 Using Antiretroviral Regimen Containing Tenofovir Alafenamide, Tenofovir Disoproxil Fumara...
Published 2022-02-01“…**Objectives:** To evaluate weight-related outcomes among patients with HIV-1 in the United States initiating ART containing different nucleoside reverse transcriptase inhibitors and doses. …”
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47
A Review of Marine Bacterial Intracellular and Extracellular Bioactive Compounds as Novel Antibacterial and Anti-Inflammation Agents
Published 2025-01-01“…A crucial resource in the ongoing search for novel peptides, proteins, lipids, nucleosides, enzymes, alkaloids, polyketides, and terpenoids is the diversity of marine bacterium strains. …”
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48
Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota
Published 2025-01-01“…The treatment altered levels of 39 and 38 metabolites produced during gut microbial and brain tissue metabolism respectively, mainly of amino acids, nucleosides, short-chain fatty acids, and essential fatty acids. …”
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49
Role of bitter contributors and bitter taste receptors: a comprehensive review of their sources, functions and future development
Published 2024-07-01“…The main bitter contributors, including phenolics, terpenoids, alkaloids, amino acids, nucleosides and purines, were summarized. The bioactivities and wide range of beneficial effects of them on anti-cancers, anti-inflammations, anti-microbes, neuroprotection, inhibiting chronic and acute injury in organs, as well as regulating behavior performance and metabolism were reported. …”
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50
Fatal Hepatic Decompensation in a Patient with Hepatitis B Cirrhosis Following Famciclovir Withdrawal
Published 2000-01-01“…No data exist regarding the safety of nucleoside analogue withdrawal in patients treated for HBV cirrhosis. …”
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51
Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe
Published 2007-01-01“…The addition of enfuvirtide and efavirenz to the present patient’s new antiretroviral regimen ensured that two fully active agents were in use in the setting of a moderate degree of nucleoside resistance and a high level of protease resistance, and where non-nucleoside reverse transcriptase inhibitors were still fully active. …”
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52
Urinary Metabolomics on the Biochemical Profiles in Diet-Induced Hyperlipidemia Rat Using Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight SYNAPT High-...
Published 2014-01-01“…Significant differences in fatty acid, amino acid, nucleoside, and bile acid were observed, indicating the perturbations of fatty acid, amino acid, nucleoside, and bile acid metabolisms in diet-induced hyperlipidaemia rats. …”
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53
Real-Life State of Anti-Hepatitis B Virus Drug Choice in Child-Bearing Age Male Patients and Effect on Fertility and Fetal Safety
Published 2019-01-01“…Research on effects of anti-hepatitis B virus (HBV) nucleoside analogs on male fertility and birth defects is limited and safety of nucleoside analogs in pregnancy is still a concern. …”
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54
Challenges in Initiating Antiretroviral Therapy in 2010
Published 2010-01-01“…The mainstay of treatment is either a non-nucleoside reverse transcriptase inhibitor or a ritonavir-boosted protease inhibitor in combination with two nucleoside reverse transcriptase inhibitors. …”
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55
Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
Published 2018-01-01“…Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. …”
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56
Purine but Not Pyrimidine De Novo Nucleotide Biosynthesis Inhibitors Strongly Enhance the Antiviral Effect of Corresponding Nucleobases Against Dengue Virus
Published 2025-01-01“…Nucleobases, the base of a nucleoside without ribose, are understudied as potential treatments for viral infections. …”
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57
Antiviral and Immunoenhancing Properties of 7-Thia-8-Oxoguanosine and Related Guanosine Analogues
Published 1992-01-01“…Immunological studies indicate that the nucleoside induces alpha-interferon and activates B cells, natural killer cells, antibody-dependent cytotoxic cells and macrophages. …”
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58
Chronic glomerulonephritis of the mixed type in patient with HBV-infection (<i>Clinical case</i>)
Published 2013-07-01“…To demonstrate efficacy of nucleoside analogues with high antiviral activity in the treatment of such patients and importance of well-timed prescription of antiviral therapy.Key points. …”
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59
Docking Studies, Synthesis, Characterization and Evaluation of Their Antioxidant and Cytotoxic Activities of Some Novel Isoxazole-Substituted 9-Anilinoacridine Derivatives
Published 2012-01-01“…The docking studies of the synthesized compounds were performed towards the key nucleoside dsDNA by using AutoDock vina 4.0 programme. …”
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60
Treatment of HIV-1 Infection with Combination Therapy: Antiretroviral Agents and Biological Response Modifiers
Published 1994-01-01“…While nucleoside antiretroviral agents are effective in delaying disease progression in human immunodeficiency virus (HIV - infected individuals. their activity is limited in magnitude and duration. …”
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